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Pregravid Weight, Prenatal Weight Gain And Maternal Age As Risk Factors In Pregnancy-Induced Hypertension Development, Maryellen C. Remich Apr 1986

Pregravid Weight, Prenatal Weight Gain And Maternal Age As Risk Factors In Pregnancy-Induced Hypertension Development, Maryellen C. Remich

Nursing Theses & Dissertations

This study examined whether the factors of pregravid weight, total prenatal weight gain at twenty-eight weeks and maternal age correlated with the development of pregnancy-induced hypertension in the third trimester. An ex post facto chart review of low risk primigravidas attending a public health maternity clinic was performed. A multiple regression correlation procedure demonstrated no significant correlation between the variables. Significant results of Chi-sguare tests of independence were demonstrated between low maternal age and pregnancy-induced hypertension development and between the failure of the mean arterial pressure to decrease in the second trimester and the development of pregnancy-induced hypertension in the …


Evidence Against The Hypothesis That Prostaglandins Are The Vasodepressor Agents Of Pregnancy. Serial Studies In Chronically Instrumented, Conscious Rats., Kirk P. Conrad, Mary C. Colpoys Jan 1986

Evidence Against The Hypothesis That Prostaglandins Are The Vasodepressor Agents Of Pregnancy. Serial Studies In Chronically Instrumented, Conscious Rats., Kirk P. Conrad, Mary C. Colpoys

Dartmouth Scholarship

Renal hemodynamics increase dramatically during pregnancy, and pressor responsiveness to exogenous administration of vasoconstrictors is attenuated. We investigated whether or not vasodilatory prostaglandins mediate these phenomena. Trained, chronically instrumented, conscious pregnant rats were used. Control values of glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were elevated at midgestation (P less than 0.01 and P = 0.05 from prepregnant means, respectively), and effective renal vascular resistance was decreased (P = 0.05). Indomethacin (4.5-6.5 mg/kg body weight [BW]) failed to decrease renal hemodynamics at this stage of pregnancy; in fact, it raised GFR somewhat further (P less than 0.05). …