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Clinical Indications Of Premenstrual Disorders And Subsequent Risk Of Injury: A Population-Based Cohort Study In Sweden, Qian Yang, Arvid Sjölander, Yuchen Li, Alexander Viktorin, Elizabeth R. Bertone-Johnson, Weimin Ye, Fang Fang, Unnur A. Valdimarsdóttir, Donghao Lu

Biostatistics and Epidemiology Faculty Publications Series

Background Premenstrual disorders, including premenstrual syndrome and premenstrual dysphoric disorder, are suggested to be correlated with suicidal behavior and accidents in cross-sectional and retrospective studies. However, prospective data are still lacking. Methods We performed a population-based cohort study including 1,472,379 Swedish women of reproductive age who were followed from 2001 to 2012. Within the cohort, we also performed a sibling analysis where we compared the rates of injury between full sisters. By linking to the Patient and the Prescribed Drug Registers, we identified 18,628 women with any clinical indications for premenstrual disorders in the cohort (population analysis) and 7674 women …