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Full-Text Articles in Medicine and Health Sciences

Scholarship Reconsidered: Implications For Reward And Recognition Of Academic Staff In Schools Of Nursing And Beyond, Kylie Smith, Patrick Crookes, Fabienne Else, Ellie Crookes Oct 2015

Scholarship Reconsidered: Implications For Reward And Recognition Of Academic Staff In Schools Of Nursing And Beyond, Kylie Smith, Patrick Crookes, Fabienne Else, Ellie Crookes

Ellie Crookes

Aims This paper discusses the issues facing the nursing academic workforce and the development of a project at the University of Wollongong in Australia which attempts to address this problem. Background The project draws on Boyers work around scholarship reconsidered to enable new ways of thinking about the nature of research and how the work of a diversifying workforce can be recognized and rewarded within institutions. Methods We conducted a series of interviews with senior university staff to identify key issues around academic promotion processes. Feedback from these interviews, along with extensive internal and external consultation and benchmarking, will be …


Bra-Breast Forces Generated In Women With Large Breasts While Standing And During Treadmill Running: Implications For Sports Bra Design, Deirdre Mcghee, Julie Steele, William Zealey, George Takacs Jul 2013

Bra-Breast Forces Generated In Women With Large Breasts While Standing And During Treadmill Running: Implications For Sports Bra Design, Deirdre Mcghee, Julie Steele, William Zealey, George Takacs

George Takacs

This study aimed to determine the bra–breast forces generated in women with large breasts while these women wore different levels of breast support during both upright standing and treadmill running. The mean bilateral vertical component of the bra–breast force in standing was 11.7 ± 4.6 N, whereas during treadmill running the mean unilateral bra–breast force was 8.7 ± 6.4 N and 14.7 ± 10.3 N in the high and low support conditions, respectively. Furthermore, breast mass was significantly correlated with vertical breast displacement (R2 = 0.62) in the high support condition. The wide range of breast masses of women with …


Dietary Consequences Of Recommending Reduced-Fat Dairy Products In The Weight-Loss Context: A Secondary Analysis With Practical Implications For Registered Dietitians, Deborah Nolan-Clark, Elizabeth Mathers, Yasmine Probst, Karen Charlton, Marijka Batterham, Linda Tapsell Apr 2013

Dietary Consequences Of Recommending Reduced-Fat Dairy Products In The Weight-Loss Context: A Secondary Analysis With Practical Implications For Registered Dietitians, Deborah Nolan-Clark, Elizabeth Mathers, Yasmine Probst, Karen Charlton, Marijka Batterham, Linda Tapsell

Karen E. Charlton

Replacing full-fat dairy products with reduced-fat varieties is a dietetic strategy for reducing energy intake while maintaining nutritional adequacy. This study aimed to explore the dietary outcomes of this recommendation in the context of weight loss. This study involved a secondary analysis of diet-history data for 86 adults (23 males and 63 females; body mass index=31.1±3.4) who had completed 3 months of a weight-loss trial in 2009, including advice to consume reduced-fat dairy products. Dairy food intake was categorized using the Australian 1995 National Nutrition Survey food hierarchy. Paired t tests and Wilcoxon signed rank tests determined dairy product consumption …


Aripiprazole Differentially Affects Mesolimbic And Nigrostriatal Dopaminergic Transmission: Implications For Long-Term Drug Efficacy And Low Extrapyramidal Side-Effects, Xu-Feng Huang, Chao Deng, Mei Han Sep 2012

Aripiprazole Differentially Affects Mesolimbic And Nigrostriatal Dopaminergic Transmission: Implications For Long-Term Drug Efficacy And Low Extrapyramidal Side-Effects, Xu-Feng Huang, Chao Deng, Mei Han

Xu-Feng Huang

Aripiprazole has been used effectively to treat schizophrenia in the clinic ; however, its mechanisms ofaction are not clear. This study examined how short- and long-term aripiprazole treatment affects dopaminergic transmission in mesolimbic and nigrostriatal pathways. For comparison, the effects of haloperidol and olanzapine treatment were also examined. Aripiprazole significantly increased D2 receptor mRNA expression and decreased tyrosine hydroxylase (TH) mRNA expression in the ventral tegmental area (VTA) after 1- and 12-wk treatment, but had no effect in substantia nigra (SN) and nucleus accumbens (NAc). Aripiprazole also decreased dopamine transporter (DAT) binding density in NAc (for 1- and 12- wk …


Rapid Cortico-Limbic Alterations In Ampa Receptor Densities After Administration Of Pcp: Implications For Schizophrenia., Van Nguyen, Kelly Newell, Xu-Feng Huang, Katerina Zavitsanou, P Ballantyne Sep 2012

Rapid Cortico-Limbic Alterations In Ampa Receptor Densities After Administration Of Pcp: Implications For Schizophrenia., Van Nguyen, Kelly Newell, Xu-Feng Huang, Katerina Zavitsanou, P Ballantyne

Xu-Feng Huang

Phencyclidine (PCP), a non-competitive NMDA/glutamate receptor antagonist, is a psychotomimetic drug that produces a syndrome in normal humans that resembles schizophrenia. The present study investigated the mechanisms of PCP actions by examining the density of glutamate and muscarinic receptors in the rat brain 4 h after a single injection of PCP. We used receptor autoradiography and [3H]MK801, [3H]AMPA, [3H]pirenzepine and [3H]AFDX384 to target glutamate NMDA, glutamate AMPA and muscarinic M1 and M2 receptors, respectively. The major outcome from the present study was an overall decrease in levels of the glutamate AMPA receptor density (F = 14.5, d.f. = 1, p …


Systematic Review And Individual Patient Data Meta-Analysis Of Diagnosis Of Heart Failure, With Modelling Of Implications Of Different Diagnostic Strategies In Primary Care, J. Mant, J. Doust, A. Roalfe, P. Barton, M. Cowie, P. Glasziou, D. Mant, R. Mcmanus, R. Holder, J. Deeks, K. Fletcher, M. Qume, S. Sohanpal, S. Sanders, F. Hobbs Dec 2008

Systematic Review And Individual Patient Data Meta-Analysis Of Diagnosis Of Heart Failure, With Modelling Of Implications Of Different Diagnostic Strategies In Primary Care, J. Mant, J. Doust, A. Roalfe, P. Barton, M. Cowie, P. Glasziou, D. Mant, R. Mcmanus, R. Holder, J. Deeks, K. Fletcher, M. Qume, S. Sohanpal, S. Sanders, F. Hobbs

Jenny Doust

Objectives: To assess the accuracy in diagnosing heart failure of clinical features and potential primary care investigations, and to perform a decision analysis to test the impact of plausible diagnostic strategies on costs and diagnostic yield in the UK health-care setting. Data sources: MEDLINE and CINAHL were searched from inception to 7 July 2006. ‘Grey literature’ databases and conference proceedings were searched and authors of relevant studies contacted for data that could not be extracted from the published papers. Review methods: A systematic review of the clinical evidence was carried out according to standard methods. Individual patient data (IPD) analysis …