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Full-Text Articles in Medicine and Health Sciences

An Overview Of Dissolved Organic Carbon In Groundwater And Implications For Drinking Water Safety, S. Regan, Paul Hynds, R. Flynn Jan 2017

An Overview Of Dissolved Organic Carbon In Groundwater And Implications For Drinking Water Safety, S. Regan, Paul Hynds, R. Flynn

Articles

Dissolved organic carbon (DOC) is composed of a diverse array of compounds, predominantly humic substances, and is a near ubiquitous component of natural groundwater, notwithstanding climatic extremes such as arid and hyper-arid settings. Despite being a frequently measured parameter of groundwater quality, the complexity of DOC composition and reaction behaviour means that links between concentration and human health risk are difficult to quantify and few examples are reported in the literature. Measured concentrations from natural/unpolluted groundwater are typically below 4 mg C/l, whilst concentrations above these levels generally indicate anthropogenic influences and/or contamination issues and can potentially compromise water safety. …


Evaluation Of Levels Of Antibiotic Resistance In Groundwater-Derived E. Coli Isolates In The Midwest Of Ireland And Elucidation Of Potential Predictors Of Resistance, Jean O'Dwyer, Paul Hynds, Matthieu Pot, Catherine Adley, Michael Ryan Jan 2017

Evaluation Of Levels Of Antibiotic Resistance In Groundwater-Derived E. Coli Isolates In The Midwest Of Ireland And Elucidation Of Potential Predictors Of Resistance, Jean O'Dwyer, Paul Hynds, Matthieu Pot, Catherine Adley, Michael Ryan

Articles

Antibiotic-resistant (pathogenic and non-pathogenic) organisms and genes are now acknowledged as significant emerging aquatic contaminants with potentially adverse human and ecological health impacts, and thus require monitoring. This study is the first to investigate levels of resistance among Irish groundwater (private wells) samples; Escherichia coli isolates were examined against a panel of commonly prescribed human and veterinary therapeutic antibiotics, followed by determination of the causative factors of resistance. Overall, 42 confirmed E. coli isolates were recovered from a groundwater-sampling cohort. Resistance to the human panel of antibiotics was moderate; nine (21.4%) E. coli isolates demonstrated resistance to one or more …


Projections Of Temperature-Related Excess Mortality Under Climate Change Scenarios, Antonio Gasparrini, Yurning Guo, Francesa Sera, Ana Maria Vicedo-Cabrera, Veronika Huber, Shilu Tong, Micheline De Sousa Zanotti Stagliorio Coelho, Paulo Saldiva, Eric Lavigne, Patricia Correa, Nicolas Valdes Ortega, Haidong Kan, Samuel Osorio, Jan Kysely, Ales Urban, Jauni Jaakkola, Niilo Ryti, Mathilde Pascal, Patrick J. Goodman, Ariana Zeka, Paola Michelozzi, Matteo Scortichini, Masahiro Hashizume, Yasushi Honda, Magali Hurtado-Diaz, Julio Cruz, Xerxes Seposo, Ho Kim, Aurelio Tobias, Carmen Iniguez, Bertil Forsberg, Daniel Astrom, Martina Ragettli, Yue Guo, Chang-Fu Wu, Antonella Zaobetti, Joel Schwartz, Michelle Bell, Tran Ngoc Dang, Duong Do Van, Clare Heaviside, Sotiris Vardoulakis, Shakoor Hajat, Andy Haines, Ben Armstrong Jan 2017

Projections Of Temperature-Related Excess Mortality Under Climate Change Scenarios, Antonio Gasparrini, Yurning Guo, Francesa Sera, Ana Maria Vicedo-Cabrera, Veronika Huber, Shilu Tong, Micheline De Sousa Zanotti Stagliorio Coelho, Paulo Saldiva, Eric Lavigne, Patricia Correa, Nicolas Valdes Ortega, Haidong Kan, Samuel Osorio, Jan Kysely, Ales Urban, Jauni Jaakkola, Niilo Ryti, Mathilde Pascal, Patrick J. Goodman, Ariana Zeka, Paola Michelozzi, Matteo Scortichini, Masahiro Hashizume, Yasushi Honda, Magali Hurtado-Diaz, Julio Cruz, Xerxes Seposo, Ho Kim, Aurelio Tobias, Carmen Iniguez, Bertil Forsberg, Daniel Astrom, Martina Ragettli, Yue Guo, Chang-Fu Wu, Antonella Zaobetti, Joel Schwartz, Michelle Bell, Tran Ngoc Dang, Duong Do Van, Clare Heaviside, Sotiris Vardoulakis, Shakoor Hajat, Andy Haines, Ben Armstrong

Articles

Summary Background Climate change can directly affect human health by varying exposure to non-optimal outdoor temperature. However, evidence on this direct impact at a global scale is limited, mainly due to issues in modelling and projecting complex and highly heterogeneous epidemiological relationships across different populations and climates. Methods We collected observed daily time series of mean temperature and mortality counts for all causes or non-external causes only, in periods ranging from Jan 1, 1984, to Dec 31, 2015, from various locations across the globe through the Multi-Country Multi-City Collaborative Research Network. We estimated temperature–mortality relationships through a two-stage time series …


Review: Epidemiological Evidence Of Groundwater Contribution To Global Enteric Disease, 1948–2015, Heather Murphy, Morgan Prioleau, Mark Borchardt, Paul Hynds Jan 2017

Review: Epidemiological Evidence Of Groundwater Contribution To Global Enteric Disease, 1948–2015, Heather Murphy, Morgan Prioleau, Mark Borchardt, Paul Hynds

Articles

Globally, approximately 2.2 billion people rely on groundwater for daily consumption. It is widely accepted that groundwater is more pristine than surface water but while this assumption is frequently the case, groundwater is not ubiquitously free of contaminants; accordingly, this presumption can result in an unfounded and potentially hazardous sense of security among owners, operators and users. The current paper presents a review of published literature providing epidemiological evidence of the contribution of groundwater to global human enteric infection. An emphasis is placed on enteric pathogens transmitted via the faecal-oral route, and specifically those associated with acute gastrointestinal illness (AGI). …