Medicine and Health Sciences Commons^™

Can Gait Signatures Provide Quantitative Measures For Aiding Clinical Decision-Making? A Systematic Meta-Analysis Of Gait Variability Behavior In Patients With Parkinson’S Disease, Niklas König Ignasiak

Physical Therapy Faculty Articles and Research

A disturbed, inconsistent walking pattern is a common feature of patients with Parkinson's disease (PwPD). Such extreme variability in both temporal and spatial parameters of gait has been associated with unstable walking and an elevated prevalence of falls. However, despite their ability to discretise healthy from pathological function, normative variability values for key gait parameters are still missing. Furthermore, an understanding of each parameter's response to pathology, as well as the inter-parameter relationships, has received little attention. The aim of this systematic literature review and meta-analysis was therefore to define threshold levels for pathological gait variability as well as to …

Revealing The Quality Of Movement: A Meta-Analysis Review To Quantify The Thresholds To Pathological Variability During Standing And Walking, Niklas König Ignasiak

Physical Therapy Faculty Articles and Research

Neuromotor processes are inherently noisy, which results in variability during movement and fluctu-ations in motor control. Although controversial, low levels of variability are traditionally considered healthy, while increased levels are thought to be pathological. This systematic review and meta-analysisof the literature investigates the thresholds between healthy and pathological task variability.

After examining 13,195 publications, 109 studies were included. Results from over 3000 healthy sub-jects and 2775 patients revealed an overall positive effect size of pathology on variability of 0.59 forwalking and 0.80 for sway. For the coefficient of variation of stride time (ST) and sway area (SA), upperthresholds of 2.6% …

Postural Responses To Perturbations Of The Vestibular System During Walking In Healthy Young And Older Adults, Jung Hung Chien

Theses & Dissertations

It has been shown that approximate one-third of US adults aged 40 years and older (69 million US citizens) have some type of vestibular problems. These declining abilities of the vestibular system affect quality of life. Difficulties in performing daily activities (dressing, bathing, getting in and out of the bed and etc.) have been highly correlated to loss of balance due to vestibular disorders. The exact number of people affected by vestibular disorders is still difficult to quantify. This might be because symptoms are difficult to describe and differences exist in the qualifying criteria within and across studies. Thus, it …

Mobility And Cognition In Seniors. Report From The 2008 Institute Of Aging (Cihr) Mobility And Cognition Workshop, Manuel Montero-Odasso, Louis Bherer, Stephanie Studenski, Karen Gopaul, Afua Oteng-Amoako, Sarah Woolmore-Goodwin, Paul Stoole, Jennie Wells, Timothy Doherty, Aleksandra A. Zecevic, David Galinsky, R. Jane Rylett, Jeffrey Jutai, Susan W. Muir-Hunter, Mark Speechley, Richard Camicioli

Physical Therapy Publications

Background

The annual Scientific Meeting of the Canadian Association on Gerontology was held on October 24 and 25, 2008 in London, Ontario. Prior to the annual meeting, mobility and cognition experts met on October 23, 2008 to engage in a pre-conference workshop.

Methods

Discussions during the workshop addressed novel areas of research and knowledge and research gaps pertaining to the interaction between mobility and cognition in seniors.

Results

Workshop presenters moved from the neuromuscular, biomechanics, and neurology of gait impairments, and falls through the role of cognition and mood on mobility regulation to the whole person in the environment. Research …

Longitudinal Quantitative Analysis Of Gait And Balance In Friedreich's Ataxia, Jeannie B. Stephenson

USF Tampa Graduate Theses and Dissertations

Friedreich's Ataxia (FA) is an autosomal-recessive, neurodegenerative disease characterized by progressive lower extremity muscle weakness and sensory loss, balance deficits, limb and gait ataxia, and dysarthria. FA is considered a sensory ataxia because the dorsal root ganglia and spinal cord dorsal columns are involved early in the disease, whereas the cerebellum is affected later. Balance deficits and gait ataxia are often evaluated clinically and in research using clinical rating scales. Recently, quantitative tools such as the Biodex Balance System SD and the GAITRite Walkway System have become available to objectively assess balance and gait, respectively. However, there are limited studies …

Specific Cognitive Domains Associated With Gait Performance In Mild Cognitive Impairment, Elyse M. Gordon

Electronic Thesis and Dissertation Repository

The study aim was to identify associations between deficits in specific cognitive domains and gait performance in Mild Cognitive Impairment (MCI). Sixty-eight participants with MCI underwent cognitive function testing in executive function (EF), attention, working memory, episodic memory and language domains. Gait was assessed using an electronic walkway (GaitRite®). The means and co-efficient of variation of five gait parameters were evaluated: velocity, stride time, stride length, step width and double support time during single (SG) and dual-task (DT) test conditions Multivariable linear regression analysis demonstrated deficits in EF, working memory and episodic memory were significantly associated with increased gait variability …