Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- TÜBİTAK (26)
- Western University (8)
- University of Alabama at Birmingham (6)
- Chapman University (5)
- University of Kentucky (5)
-
- Virginia Commonwealth University (4)
- Thomas Jefferson University (3)
- University of Texas Rio Grande Valley (3)
- Valparaiso University (3)
- Wayne State University (3)
- City University of New York (CUNY) (2)
- Edith Cowan University (2)
- LSU Health Science Center (2)
- Ohio Northern University (2)
- Old Dominion University (2)
- SelectedWorks (2)
- University of Nebraska - Lincoln (2)
- University of North Dakota (2)
- University of Vermont (2)
- Aga Khan University (1)
- Al-Azhar University (1)
- California State University, San Bernardino (1)
- Chulalongkorn University (1)
- HCA Healthcare (1)
- James Madison University (1)
- Kutztown University (1)
- Liberty University (1)
- Marshall University (1)
- Northern Illinois University (1)
- Philadelphia College of Osteopathic Medicine (1)
- Publication Year
- Publication
-
- Turkish Journal of Medical Sciences (26)
- Brain and Mind Institute Researchers' Publications (7)
- All ETDs from UAB (6)
- Journal of Mind and Medical Sciences (3)
- Theses and Dissertations (3)
-
- Biomedical Sciences Posters and Presentations (2)
- Food for Health: Publications (2)
- Medical Student Research Symposium (2)
- Neurosurgery Faculty Publications (2)
- Paula Diehr (2)
- Pharmacy and Wellness Review (2)
- Publications and Research (2)
- Research outputs 2014 to 2021 (2)
- School of Medicine Faculty Publications (2)
- School of Medicine Publications and Presentations (2)
- Al-Azhar International Medical Journal (1)
- Biology Faculty Publications (1)
- Chulalongkorn Medical Journal (1)
- Community & Environmental Health Faculty Publications (1)
- DNP Projects (1)
- Department of Biological & Biomedical Sciences (1)
- Department of Medicine Faculty Papers (1)
- Department of Neurosurgery Faculty Papers (1)
- Doctor of Nursing Practice Projects (1)
- Electronic Theses and Dissertations (1)
- Electronic Theses, Projects, and Dissertations (1)
- Electronic Thesis and Dissertation Repository (1)
- English Department: Research for Change - Wicked Problems in Our World (1)
- Family Medicine Clerkship Student Projects (1)
- Graduate College Dissertations and Theses (1)
Articles 31 - 60 of 106
Full-Text Articles in Medicine and Health Sciences
Assessment Of Major Depressive Disorders Through Neuroimaging Studies And Their Treatment Methods, Jevetha Vijayadasan, Diksha Raghunathan, Sivakumar Rajagopal, Rahul Soangra
Assessment Of Major Depressive Disorders Through Neuroimaging Studies And Their Treatment Methods, Jevetha Vijayadasan, Diksha Raghunathan, Sivakumar Rajagopal, Rahul Soangra
Physical Therapy Faculty Articles and Research
Many mental disorders are caused due to improper regulation of the brain and depression is one such. It affects both children and adults and is very common among teenagers. There are many challenges clinicians face regarding the management of this disease. These challenges have prompted the development of various neuroimaging techniques that effectively diagnose the condition. The main techniques are Magnetic resonance imaging (MRI) and Positron emission tomography (PET) which have gained momentum over the years. Advanced MRI techniques help study certain regions of the brain such as hippocampus and amygdala. Effective treatments for depression include antidepressant medications and brain …
Chronic Use Of Non-Medical Abdominal Compressors: Medical And Psychological Implications, Sawsan Edriss, Bushra Azom, Manar Edriss, Mustafa Edriss, Ann-Cathrin Guertler, Eva Waineo Md, Diane L. Levine Md
Chronic Use Of Non-Medical Abdominal Compressors: Medical And Psychological Implications, Sawsan Edriss, Bushra Azom, Manar Edriss, Mustafa Edriss, Ann-Cathrin Guertler, Eva Waineo Md, Diane L. Levine Md
Medical Student Research Symposium
The popularity of waist cinchers, shapewear, abdominal binders, corsets, and waist trainers has increased in the population. Although corsets have been part of western fashion since the 18th century, abdominal compressors remain in style even today. In 2018, sales for shapewear worldwide were estimated at 2.26 billion USD. 1 Despite its popularity, shapewear safety and medical effects have not been widely studied.
In 1968, “Pantygirdle Syndrome” was described, attributing vulvitis, urethritis, and urinary tract infections to materials used from the “pantygirdle”. 2 The article describes that the girdle caused gastrointestinal symptoms with diaphragmatic and stomach displacement causing gastro-esophageal reflux disease …
Patterns Of Cilia Gene Dysregulations In Major Psychiatric Disorders, Wedad Alhassen, Siwei Chen, Marquis Vawter, Brianna Kay Robbins, Henry Nguyen, Thant Nyi Myint, Yumiko Saito, Anton Schulmann, Surya M. Nauli, Olivier Civelli, Pierre Baldi, Amal Alachkar
Patterns Of Cilia Gene Dysregulations In Major Psychiatric Disorders, Wedad Alhassen, Siwei Chen, Marquis Vawter, Brianna Kay Robbins, Henry Nguyen, Thant Nyi Myint, Yumiko Saito, Anton Schulmann, Surya M. Nauli, Olivier Civelli, Pierre Baldi, Amal Alachkar
Pharmacy Faculty Articles and Research
Primary cilia function as cells' antennas to detect and transduce external stimuli and play crucial roles in cell signaling and communication. The vast majority of cilia genes that are causally linked with ciliopathies are also associated with neurological deficits, such as cognitive impairments. Yet, the roles of cilia dysfunctions in the pathogenesis of psychiatric disorders have not been studied. Our aim is to identify patterns of cilia gene dysregulation in the four major psychiatric disorders: schizophrenia (SCZ), autism spectrum disorder (ASD), bipolar disorder (BP), and major depressive disorder (MDD). For this purpose, we acquired differentially expressed genes (DEGs) from the …
Association Of Physical Frailty With Cognitive Function And Mood In Older Adults Without Dementia And Depression, Rana Tuna Doğrul, Hacer Doğan Varan, Muhammet Cemal Kizilarslanoğlu, Mustafa Kemal Kiliç, Özgür Kara, Güneş Arik, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu
Association Of Physical Frailty With Cognitive Function And Mood In Older Adults Without Dementia And Depression, Rana Tuna Doğrul, Hacer Doğan Varan, Muhammet Cemal Kizilarslanoğlu, Mustafa Kemal Kiliç, Özgür Kara, Güneş Arik, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu
Turkish Journal of Medical Sciences
Background/aim: Physical frailty is thought to be related with a decline in cognitive function, mood, and social activities, especially in patients with depression and dementia. It is not clear whether or not physical frailty is associated with an impairment in cognitive function and mood in patients without dementia and depression. In this study, we evaluated the association of physical frailty with cognitive function and mood in geriatric patients without dementia and depression. Material and methods: In this study, 612 patients aged 65 years and over were evaluated. Physical frailty was assessed by using Fried criteria. Furthermore, comprehensive geriatric assessment was …
Behavioural Phenotyping Of Thunder Mice With A Hypomorphic Mutation Of Heterogeneous Nuclear Ribonuclear Protein L-Like (Hnrnpll) And Reduced T Cell Function, Maarten Van Den Buuse, Paul Halley, Gerard Hoyne
Behavioural Phenotyping Of Thunder Mice With A Hypomorphic Mutation Of Heterogeneous Nuclear Ribonuclear Protein L-Like (Hnrnpll) And Reduced T Cell Function, Maarten Van Den Buuse, Paul Halley, Gerard Hoyne
Medical Papers and Journal Articles
Heterogeneous nuclear ribonuclear protein l-like (hnRNPLL) is an RNA binding protein that regulates alternative splicing of mRNA and is abundantly expressed in memory T lymphocytes of the immune system and in the brain. A hypomorphic allele of the gene encoding hnRNPLL (Hnrpllthunder) selectively reduces T cell accumulation in lymphoid tissues, but little is known about its effects in the brain. Therefore, we exposed Hnrpllthunder mice to a test battery with relevance for a range of psychiatric illnesses. Thunder mice showed enhanced immobility in the tail-suspension test for depression-related behaviours, impaired short-term spatial memory in the Y-maze and reduced …
Diffusion Dispersion Imaging: Mapping Oscillating Gradient Spin-Echo Frequency Dependence In The Human Brain., Aidin Arbabi, Jason Kai, Ali R Khan, Corey A Baron
Diffusion Dispersion Imaging: Mapping Oscillating Gradient Spin-Echo Frequency Dependence In The Human Brain., Aidin Arbabi, Jason Kai, Ali R Khan, Corey A Baron
Brain and Mind Institute Researchers' Publications
PURPOSE: Oscillating gradient spin-echo (OGSE) diffusion MRI provides information about the microstructure of biological tissues by means of the frequency dependence of the apparent diffusion coefficient (ADC). ADC dependence on OGSE frequency has been explored in numerous rodent studies, but applications in the human brain have been limited and have suffered from low contrast between different frequencies, long scan times, and a limited exploration of the nature of the ADC dependence on frequency.
THEORY AND METHODS: Multiple frequency OGSE acquisitions were acquired in healthy subjects at 7T to explore the power-law frequency dependence of ADC, the "diffusion dispersion." Furthermore, a …
Scope Of Attention Variation As A Function Of Anxiety And Depression, Kathleen O'Donnell
Scope Of Attention Variation As A Function Of Anxiety And Depression, Kathleen O'Donnell
Electronic Theses, Projects, and Dissertations
As a social species, correct emotional perception is so vital, that the human brain has evolved a mechanism to control attentional choices by exerting a narrowed field of perception during danger, called the scope of attention (SoA). The SoA determines what information will be focused on or ignored by blocking the perception of non-relevant items and increasing selective focus on danger; even if danger is merely a sad-face. The emotional items blocked from perception cannot be remembered because they were never perceived. But, attention-control to emotional stimuli also varies with mood, as seen in mood-disorders. A mood-disorder’s effect upon the …
Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden
Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden
Brain and Mind Institute Researchers' Publications
© 2020 The Author(s) Self-referential processing (i.e., self-schemas that guide processing of self-descriptive information) emerges early in youth, with deeper encoding of negative self-descriptors and/or shallower encoding of positive self-descriptors causally linked to depression. However, the relationship between depressogenic self-schemas and brain structure is unclear. We investigated associations between self-schemas and regional grey matter volume (GMV) in 84 never-depressed preadolescents oversampled for depression risk based on maternal depression history. Self-schemas were assessed using a Self-Referent Encoding Task (SRET) and regional GMV was indexed via voxel-based morphometry analysis of structural magnetic resonance imaging data. Youths’ positive self-schemas were associated with greater …
Orbitofrontal Cortex Grey Matter Volume Is Related To Children's Depressive Symptoms, Matthew R.J. Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R. Daoust, Marc F. Joanisse, Deanna M. Barch, Elizabeth P. Hayden
Orbitofrontal Cortex Grey Matter Volume Is Related To Children's Depressive Symptoms, Matthew R.J. Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R. Daoust, Marc F. Joanisse, Deanna M. Barch, Elizabeth P. Hayden
Brain and Mind Institute Researchers' Publications
© 2020 The Author(s) Adults with a history of depression show distinct patterns of grey matter volume (GMV) in frontal cortical (e.g., prefrontal cortex, orbitofrontal cortex) and limbic (e.g., anterior cingulate, amygdala, hippocampus, dorsal striatum) structures, regions relevant to the processing and regulation of reward, which is impaired in the context of depression. However, it is unclear whether these GMV associations with depression precede depressive disorder onset or whether GMV is related to early emerging symptoms or familial depression. To address these questions, we used voxel-based morphometry (VBM) to examine GMV in 85 community-dwelling children (M = 11.12 years, SD …
The Association Between Temperament Features And Childhood Traumas In Patients With Juvenile Myoclonic Epilepsy, Ali̇şan Burak Yaşar, Ceyhun Sayman, Serap Erdoğan Taycan, Yilmaz Çeti̇nkaya, Anil Gündüz, Hülya Ti̇reli̇
The Association Between Temperament Features And Childhood Traumas In Patients With Juvenile Myoclonic Epilepsy, Ali̇şan Burak Yaşar, Ceyhun Sayman, Serap Erdoğan Taycan, Yilmaz Çeti̇nkaya, Anil Gündüz, Hülya Ti̇reli̇
Turkish Journal of Medical Sciences
Background/aim: Epilepsy is a common chronic neurological problem that impairs daily activities, functionality, and quality of life. Childhood traumas (CTs) are known to be critical factors in the onset or development of many psychiatric and medical disorders. They also play a critical role in the development of temperament and personality. This study aimed to investigate the association between CTs and common temperament patterns and features seen in epilepsy patients. Materials and methods: The study included 38 patients who were diagnosed with juvenile myoclonic epilepsy (JME) and volunteered to participate in the study. In addition to the sociodemographic form and questions …
Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden
Depressogenic Self-Schemas Are Associated With Smaller Regional Grey Matter Volume In Never-Depressed Preadolescents, Pan Liu, Matthew R.J. Vandemeer, Marc F. Joanisse, Deanna M. Barch, David J.A. Dozois, Elizabeth P. Hayden
Brain and Mind Institute Researchers' Publications
© 2020 The Author(s) Self-referential processing (i.e., self-schemas that guide processing of self-descriptive information) emerges early in youth, with deeper encoding of negative self-descriptors and/or shallower encoding of positive self-descriptors causally linked to depression. However, the relationship between depressogenic self-schemas and brain structure is unclear. We investigated associations between self-schemas and regional grey matter volume (GMV) in 84 never-depressed preadolescents oversampled for depression risk based on maternal depression history. Self-schemas were assessed using a Self-Referent Encoding Task (SRET) and regional GMV was indexed via voxel-based morphometry analysis of structural magnetic resonance imaging data. Youths’ positive self-schemas were associated with greater …
Orbitofrontal Cortex Grey Matter Volume Is Related To Children's Depressive Symptoms, Matthew R.J. Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R. Daoust, Marc F. Joanisse, Deanna M. Barch, Elizabeth P. Hayden
Orbitofrontal Cortex Grey Matter Volume Is Related To Children's Depressive Symptoms, Matthew R.J. Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R. Daoust, Marc F. Joanisse, Deanna M. Barch, Elizabeth P. Hayden
Brain and Mind Institute Researchers' Publications
© 2020 The Author(s) Adults with a history of depression show distinct patterns of grey matter volume (GMV) in frontal cortical (e.g., prefrontal cortex, orbitofrontal cortex) and limbic (e.g., anterior cingulate, amygdala, hippocampus, dorsal striatum) structures, regions relevant to the processing and regulation of reward, which is impaired in the context of depression. However, it is unclear whether these GMV associations with depression precede depressive disorder onset or whether GMV is related to early emerging symptoms or familial depression. To address these questions, we used voxel-based morphometry (VBM) to examine GMV in 85 community-dwelling children (M = 11.12 years, SD …
Subanesthetic Iv Ketamine Reduces Acute Suicidal Ideation In Patients With Mood Disorders, Kimberly Jenko, Jack Anzilotti
Subanesthetic Iv Ketamine Reduces Acute Suicidal Ideation In Patients With Mood Disorders, Kimberly Jenko, Jack Anzilotti
Physician Assistant Capstones, 2016 to 2019
Background. Depression and suicide are common in the United States and present a significant problem in the healthcare landscape. Currently, there are few options that can rapidly reduce suicidal ideation in patients with depression. Ketamine, a glutamate N-methyl-D-aspartate (NMDA) receptor antagonist, has been shown to reduce acute suicidality in patients with depression. Previous studies have a reduction of suicidal ideation compared to saline placebo, but few studies have shown a significant effect compared to a similar psychoactive drug such as midazolam.
Method. A search of PubMed and PsychNET was performed in September 2018 using the terms “ketamine,” “suicide,” …
Burnout, Job Dissatisfaction, And Mental Health Outcomes Among Medical Students And Health Care Professionals At A Tertiary Care Hospital In Pakistan: Protocol For A Multi-Center Cross-Sectional Study, Syed Hamza Mufarrih, Aeman Naseer, Nada Qaisar Qureshi, Zohaib Anwar, Nida Zahid, Riaz Hussain Lakdawala, Shahryar Noordin
Burnout, Job Dissatisfaction, And Mental Health Outcomes Among Medical Students And Health Care Professionals At A Tertiary Care Hospital In Pakistan: Protocol For A Multi-Center Cross-Sectional Study, Syed Hamza Mufarrih, Aeman Naseer, Nada Qaisar Qureshi, Zohaib Anwar, Nida Zahid, Riaz Hussain Lakdawala, Shahryar Noordin
Department of Biological & Biomedical Sciences
Burnout, a state of vital exhaustion, has frequently been related to work-related stress and job dissatisfaction. Given the emotionally and physically challenging nature of their work, high rates of burnout have been reported among health care professionals. This may put them at a higher risk for of suffering from adverse mental health outcomes, including depression, anxiety and stress. In our study, we aim to assess the prevalence i of and associations among burnout and job dissatisfaction and adverse mental health outcomes in a developing country, where the challenges faced by the health care system are unique. Facilities are over-burdened and …
Acute Diagnosis Of Wilson’S Disease In A Teenage Patient, Sarah Irvin, Ryan Mccarthy
Acute Diagnosis Of Wilson’S Disease In A Teenage Patient, Sarah Irvin, Ryan Mccarthy
Marshall Journal of Medicine
Wilson’s Disease, a rare autosomal recessive genetic disease, is caused by a mutation in the ATP7B enzyme gene. Without this enzyme, copper builds up in the brain, liver, and cornea causing a multitude of symptoms. It is important to consider Wilson’s disease because the prognosis is dependent on timely diagnosis. This is an interesting case of a 19-year-old male who presented with suicidal thoughts and rapid weight loss. After many months and an extensive work-up, Wilson’s Disease was diagnosed. Due to his rapid decline, he was transferred to a larger university healthcare center where he is currently enrolled in clinical …
Antidepressant Dosing In Major Depression: A Pharmacogenomic Approach, Morgan Homan, Haval Norman, Victoria Cho, Yousif Rojeab
Antidepressant Dosing In Major Depression: A Pharmacogenomic Approach, Morgan Homan, Haval Norman, Victoria Cho, Yousif Rojeab
Pharmacy and Wellness Review
Major depressive disorder (MDD) is the most predominant mental disorder in the United States, with serious and costly health risks if not successfully managed. Pharmacotherapy is a standard option for MDD treatment, but patients often require extensive therapy adjustments to find a suitable regimen. Pharmacogenomics may enable greater precision in antidepressant therapy. Genotypic variations in CYP2D6 and CYP2C19 metabolic enzymes are reliable predictors of serum drug concentration, but the complex dose-response relationship of antidepressants prevents such variations from predicting therapy success. Additionally, ABCBl has been examined for its role in P-glycoprotein efflux of antidepressants in the brain, yet it is …
Neonatal Abstinence Syndrome From Selective Serotonin Reuptake Inhibitor Use During Pregnancy, Elizabeth Kramer, Maria Patnella, Rachel Bulko, Allie Harrison, Hannah Lamb, Manoranjan D'Souza
Neonatal Abstinence Syndrome From Selective Serotonin Reuptake Inhibitor Use During Pregnancy, Elizabeth Kramer, Maria Patnella, Rachel Bulko, Allie Harrison, Hannah Lamb, Manoranjan D'Souza
Pharmacy and Wellness Review
Neonatal abstinence syndrome (NAS) is a concern for infants born to mothers receiving treatment with a selective serotonin reuptake inhibitor (SSRI) throughout the pregnancy. The risk of NAS associated with SSRI use during pregnancy varies with the specific SSRI that is used by the patient during pregnancy. Common symptoms of NAS include premature delivery, gastrointestinal disturbances, irritability, low birth weight, short length and lack of response to various stimuli. Neonates that present with these symptoms can be scored using either the Finnegan or Lipsitz scoring tools. Neonates experiencing NAS can be calmed or treated using nonpharmacologic methods such as swaddling, …
Probiotic Administration As An Adjuvant Therapeutic Treatment For Anxiety, Depression, And Cognitive Impairment Among Hypothyroid Patients, Erin R. Gorman
Probiotic Administration As An Adjuvant Therapeutic Treatment For Anxiety, Depression, And Cognitive Impairment Among Hypothyroid Patients, Erin R. Gorman
Selected Honors Theses
Hypothyroidism is a form of thyroid dysfunction that occurs when the thyroid gland does not make and secrete enough thyroid hormones to regulate certain processes in the body. Because thyroid hormones take part in many bodily functions, hypothyroidism can cause a large range of symptoms. Current research indicates that some strains of probiotics have beneficial effects on certain neurological and inflammatory diseases, leading to the impression that they can be used therapeutically for effective treatment of different mental health issues such as anxiety, stress, depression, and impaired memory. Because hypothyroidism often leads to such mental symptoms, it may be possible …
The Influence Of Unpredictable, Fragmented Parental Signals On The Developing Brain, Laura M. Glynn, Tallie Z. Baram
The Influence Of Unpredictable, Fragmented Parental Signals On The Developing Brain, Laura M. Glynn, Tallie Z. Baram
Psychology Faculty Articles and Research
Mental illnesses originate early in life, governed by environmental and genetic factors. Because parents are a dominant source of signals to the developing child, parental signals - beginning with maternal signals in utero - are primary contributors to children’s mental health. Existing literature on maternal signals has focused almost exclusively on their quality and valence (e.g. maternal depression, sensitivity). Here we identify a novel dimension of maternal signals: their patterns and especially their predictability/unpredictability, as an important determinant of children’s neurodevelopment. We find that unpredictable maternal mood and behavior presage risk for child and adolescent psychopathology. In experimental models, fragmented/unpredictable …
Intensive Care Psychological Assessment Tool (Ipat): Turkish Validity And Reliability Study, Berker Duman, Zeynep Kotan, Vahap Ozan Kotan, Nevzat Mehmet Mutlu, Beyza Doğanay Erdoğan, Damla Sayar Akaslan, Safi̇ye Zeynep Tatli, Hakan Kumbasar
Intensive Care Psychological Assessment Tool (Ipat): Turkish Validity And Reliability Study, Berker Duman, Zeynep Kotan, Vahap Ozan Kotan, Nevzat Mehmet Mutlu, Beyza Doğanay Erdoğan, Damla Sayar Akaslan, Safi̇ye Zeynep Tatli, Hakan Kumbasar
Turkish Journal of Medical Sciences
Background/aim: It is of crucial importantance to be able to detect acute psychological distress in patients. The Intensive Care Psychological Assessment Tool (IPAT) was developed for this purpose in intensive care units. This study aims to evaluate the validity and reliability of the Turkish version of IPAT.Materials and methods: In total, 98 patients were included. To assess concurrent validity, the Intensive Care Experiences Scale (ICES) and the Hospital Anxiety Depression Scale were performed. Cronbach?s alpha coefficient was used to estimate internal consistency. Interitem and item-total score correlations were also performed. Sensitivity and specificity were derived for concurrent anxiety and depression.Results: …
Testing The Efficacy Of Transcranial Magnetic Stimulation (Tms) In Treating Depression In Patients With Cognitive Impairment, Daniel Robert Schaffer
Testing The Efficacy Of Transcranial Magnetic Stimulation (Tms) In Treating Depression In Patients With Cognitive Impairment, Daniel Robert Schaffer
Psychology Theses & Dissertations
The purpose of this study is to (1) examine the efficacy of Transcranial Magnetic Stimulation (TMS) in treating depression among individuals with cognitive impairment and (2) to examine if TMS is capable of facilitating cognitive improvements independent of mood improvements. Mild cognitive impairment (MCI) is often seen as a pre-clinical stage to dementia, and depressive disorders are highly prevalent among both MCI and dementia. There is a large body of research that has linked depressive disorders as a prodromal symptom of MCI and the later development of dementia. While some researchers debate whether or not this link between depression and …
Anxiety And Depression States Of Adolescents With Polycystic Ovary Syndrome, Hamdi̇ Ci̇han Emeksi̇z, Aysun Bi̇deci̇, Burçi̇n Nalbantoğlu, Ayşi̇n Nalbantoğlu, Cem Çeli̇k, Yasemi̇n Yulaf, Mahmut Orhun Çamurdan, Peyami̇ Ci̇naz
Anxiety And Depression States Of Adolescents With Polycystic Ovary Syndrome, Hamdi̇ Ci̇han Emeksi̇z, Aysun Bi̇deci̇, Burçi̇n Nalbantoğlu, Ayşi̇n Nalbantoğlu, Cem Çeli̇k, Yasemi̇n Yulaf, Mahmut Orhun Çamurdan, Peyami̇ Ci̇naz
Turkish Journal of Medical Sciences
Background/aim: Various studies have shown that adult patients with polycystic ovary syndrome (PCOS) have higher levels of anxiety and depression compared to their normal counterparts. However, it is still unclear whether these mood disorders already exist in adolescents affected by PCOS. The aim of the present study is to assess differences in anxiety and depression levels between adolescents with PCOS and age- and body mass index (BMI)-matched controls and to determine the possible factor(s) impacting these psychological parameters in adolescents with PCOS. Materials and methods: The study included 80 adolescents with PCOS and 50 age- and BMI-matched controls. All participants …
Early Diagnosis And Nutritional Treatment Stabilizes Neuropsychiatric Disorders, Ian James Martins
Early Diagnosis And Nutritional Treatment Stabilizes Neuropsychiatric Disorders, Ian James Martins
Research outputs 2014 to 2021
The reliable diagnostic identification of neuropsychiatric disorders such as schizophrenia, bipolar disease, and depression has been associated with some biological markers (genomics, proteomics, metabolomics) but to date, these markers do not have the sensitivity/specificity of a diagnostic test. Biomarker tests that are relevant to global chronic disease are now applicable to neuropsychiatric diseases to prevent autoimmune disease, endoplasmic reticulum stress associated mitophagy with relevance to neuron apoptosis. Metabolic abnormalities has been linked to neuropsychiatric disorder with the careful nutritional assessment of patients reported in many published studies. Early interventions with genomic medicine now assist in the prevention of autoimmune disease …
Factors Associated With Social Anxiety Disorder In A Group Of Obese Turkish Female Patients, Akatli Kürşad Özşahi̇n, Ebru Altintaş
Factors Associated With Social Anxiety Disorder In A Group Of Obese Turkish Female Patients, Akatli Kürşad Özşahi̇n, Ebru Altintaş
Turkish Journal of Medical Sciences
Background/aim: Mental disorders may accompany obesity. is study aims to evaluate the association between social anxiety disorder (SAD) and obesity and the risk factors for SAD in obese female patients. Materials and methods: A total of 114 obese patients and 110 healthy controls were included. The Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), State and Trait Anxiety Inventory (STAI I-II), and Liebowitz Social Anxiety Scale (LSAS) were administered to assess anxiety, depression, and social anxiety levels. Scale scores were analyzed statistically. Results: The rate of SAD in obese female patients was found to be 8.8%. Anxiety, depression, and social …
The Effects Of Ketamine And Other Rapid Antidepressants On Hippocampal Circuits, Allie J. Widman
The Effects Of Ketamine And Other Rapid Antidepressants On Hippocampal Circuits, Allie J. Widman
All ETDs from UAB
Major Depressive Disorder (MDD) in a common mental disorder that can impair cognitive functioning and negatively impact hippocampus. While several pharmacological treatments are currently available for MDD, most target the monoamine system, providing little variety in approaching treatment. Additionally, a large percentage of people with MDD have an inadequate response to this drug class, leaving them with little optimism of a full functional recovery. Recently, low-dose ketamine, an open-channel N-methyl D-aspartate receptor (NMDAR) antagonist, produced rapid antidepressant effects in humans, including people who do not respond to monoamine-based therapies, that lasted for days. The antidepressant-like behavioral effect of ketamine is …
The Association Of Hormonal Contraception With Depression, Pamela Derickson
The Association Of Hormonal Contraception With Depression, Pamela Derickson
Family Medicine Clerkship Student Projects
Hormonal contraceptives are widely used by women during their reproductive years. Currently, over 100 million women worldwide use the pill, and 82% of sexually active women in the USA will use oral contraceptive pills at some time during their reproductive years (Carrol, 2017). Oral contraceptive use, especially among adolescents, is associated with subsequent use of antidepressants and a first diagnosis of depression, suggesting depression may be a potential adverse effect of hormonal contraceptive use (Skovlund, 2016). This project focused on educating health care providers at the Community Health Center of Burlington, VT (CHCB) about the association of depression and oral …
The Impact Spectrum Of Head Injuries On The Sport Of Hockey, Caleb W. Neal
The Impact Spectrum Of Head Injuries On The Sport Of Hockey, Caleb W. Neal
Senior Honors Projects
The Center for Disease Control and Prevention (CDC) estimates there are between 1.6-3.8 million sports and recreation related concussions per year. In fact there are over 4 million concussions (including non-sports related) in total each year. A concussion is defined as a serious brain injury caused by the rapid movement (linear front-to-back, side-to-side) or rotational (angular) movement of the brain inside the skull, which results in damage and disruption to the brain cell function, causing brain trauma (sports concussion library). Sports-related concussions (SRCs) are concussions that are specifically sustained during a sporting event. The sport with the highest incidence of …
Research Methods In Occupational Health Psychology, Irvin Sam Schonfeld, Chu-Hsiang Chang
Research Methods In Occupational Health Psychology, Irvin Sam Schonfeld, Chu-Hsiang Chang
Publications and Research
http://www.springerpub.com/occupational-health-psychology.html
Occupational Health Psychology (OHP) is a rapidly expanding interdisciplinary field that focuses on the science and practice of psychology in promoting and developing workplace health- and safety-related initiatives. This comprehensive text for undergraduate and graduate survey courses is the first to encompass a wide range of key issues in OHP. It draws from the domains of psychology, public health, preventive medicine,nursing, industrial engineering, law, and epidemiology to focus on the theory and practice of protecting and promoting the health, well-being, and safety of individuals in the workplace and improving the quality of work life.
The text addresses key psychosocial …
Sleep Disturbances And Depression: The Role Of Genes And Trauma, Mackenzie J. Lind
Sleep Disturbances And Depression: The Role Of Genes And Trauma, Mackenzie J. Lind
Theses and Dissertations
Sleep disturbances and insomnia are prevalent, with around 33% of adults indicating that they experience at least one main symptom of insomnia, and bidirectional relationships exist with common psychopathology, particularly major depressive disorder (MDD). However, genetic and environmental (e.g., traumatic event exposure) contributions to the etiology of these phenotypes are not yet well understood. A genetically informative sample of approximately 12,000 Han Chinese women aged 30-60 (50% with recurrent MDD) was used to address several gaps within the sleep literature. Sleep disturbances were assessed in all individuals using a general item addressing sleeplessness (GS). A sleep within depression sum score …
Cross-Cultural Adaptation And Psychometric Assessment Of The Turkishversion Of The Vulnerability To Abuse Screening Scale, Güler Duru Aşi̇ret, Gülcan Bağçi̇van, Münevver Özcan, Beste Başak Eröksüz, Nalan Akbayrak, Nuran Akdemi̇r
Cross-Cultural Adaptation And Psychometric Assessment Of The Turkishversion Of The Vulnerability To Abuse Screening Scale, Güler Duru Aşi̇ret, Gülcan Bağçi̇van, Münevver Özcan, Beste Başak Eröksüz, Nalan Akbayrak, Nuran Akdemi̇r
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate the reliability and validity of the Turkish version of the Vulnerability to Abuse Screening Scale (VASS). Materials and methods: This was a methodological study. The sample included 140 elderly individuals. Data were collected by using a questionnaire form, the VASS, and the Geriatric Depression Scale (GDS). The Cronbach alpha value was calculated and test?retest reliability was tested for the reliability analyses. Results: The Cronbach alpha value calculated for the VASS (12 items) was 0.819. There was no difference between test and retest mean scores of the VASS. A statistically significantly positive …