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Full-Text Articles in Medicine and Health Sciences
Impact Of Ph On The Activity Of Co-Used Antimicrobials Against Resistant Escherichia Colistrains Of Animal Origin, Murat Cengi̇z, Gülçe Hepbostanci
Impact Of Ph On The Activity Of Co-Used Antimicrobials Against Resistant Escherichia Colistrains Of Animal Origin, Murat Cengi̇z, Gülçe Hepbostanci
Turkish Journal of Veterinary & Animal Sciences
In this study, combination antimicrobial therapy, due to its higher potential against resistant bacteria, was evaluated for the inhibition of multidrug-resistant E. coli strains. The influence of pH as an environmental variable on the activity of antimicrobial combinations was evaluated by calculating the factional concentration indexes at pH values 5.0, 6.0, 7.3, and 8.0. The highest synergistic activity rates of ceftriaxone + colistin, danofloxacin + colistin, danofloxacin + ceftiofur, and ceftiofur + gentamicin combinations were 50%, 33%, 100%, and 50%, respectively measured at ≥7.3 pH. The lowest synergistic activity rates for all combinations were observed at the acidic pH values …
High Level Fluoroquinolone Resistance In Escherichia Coli Isolatedfrom Animals In Turkey Is Due To Multiple Mechanisms, Pinar Şahi̇ntürk, Erdem Arslan, Esra Büyükcangaz, Songül Sonal, Ayşi̇n Şen, Fi̇gen Ersoy, Mark A. Webber, Laura Jv. Piddock, Murat Cengi̇z
High Level Fluoroquinolone Resistance In Escherichia Coli Isolatedfrom Animals In Turkey Is Due To Multiple Mechanisms, Pinar Şahi̇ntürk, Erdem Arslan, Esra Büyükcangaz, Songül Sonal, Ayşi̇n Şen, Fi̇gen Ersoy, Mark A. Webber, Laura Jv. Piddock, Murat Cengi̇z
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to determine the molecular mechanisms of fluoroquinolone resistance in E. Coli isolated from cattle, goats, sheep, cats, and dogs in Turkey. Twenty nonreplicate E. Coli isolates (chosen on the basis of RAPD pattern) from food-producing animals were selected for the study. To identify phenotypic differences between isolates, the sum of the MIC values of 14 antimicrobials was calculated; values ranged from 565 to 2520 μg/mL, indicating the diversity in antimicrobial resistance present in the panel of isolates. PCR and qRT-PCR were used to characterize the presence and expression levels of known molecular mechanisms of …
Radionuclide Exposure In Animals And The Public Health Implications, Roseline Yemisi Olobatoke, Manny Mathuthu
Radionuclide Exposure In Animals And The Public Health Implications, Roseline Yemisi Olobatoke, Manny Mathuthu
Turkish Journal of Veterinary & Animal Sciences
Living tissues are usually exposed to varying degrees of radiation from natural and manmade radioactive substances. Depending on the type of radiation emitted and rate and dose of absorption, all radioactive substances are potentially hazardous. Previous researches on the biological effects of radiation as well as preventive measures have focused on human subjects, being the most radiosensitive species. However, exposure of animals to ionizing irradiation may negatively influence their production performance, resulting in some level of economic loss. In addition, many food animals may represent a significant pathway for transfer of radionuclides to humans, thereby adding to the exposure burden. …
Anticoagulant Rodenticide Intoxication In Animals – A Review, Ivan Valchev, Rumen Binev, Veska Yordanova, Yordan Nikolov
Anticoagulant Rodenticide Intoxication In Animals – A Review, Ivan Valchev, Rumen Binev, Veska Yordanova, Yordan Nikolov
Turkish Journal of Veterinary & Animal Sciences
The newest measures for the control of harmful rodent populations are from the anticoagulant rodenticide group, which are divided into 2 subgroups: first and second generations, and indandione derivatives. Non-target organisms are potentially at risk of direct consumption of baits (primary hazard) and of eating poisoned rodents (secondary hazard). Anticoagulant rodenticides inhibit the enzyme vitamin K-dependent carboxylase and thus impair the reactivation of vitamin K1, indirectly affecting physiological blood coagulation. The diagnosis is made on the basis of clinical signs (massive hemorrhages), laboratory findings, and especially the changes in coagulation markers (APTT, PT, TT, PCT, ACT, FDPs, and PIVKA). The …
Determination Of Some Virulence Factors In Staphylococcus Spp. Isolated From Various Clinical Samples, Süheyla Türkyilmaz, Osman Kaya
Determination Of Some Virulence Factors In Staphylococcus Spp. Isolated From Various Clinical Samples, Süheyla Türkyilmaz, Osman Kaya
Turkish Journal of Veterinary & Animal Sciences
The objectives of this study were to identify staphylococci isolated from different animal clinical samples, to examine some of the virulence factors in the isolates, to determine relationships between these virulence factors and coagulase positive Staphylococcus (CoPS)/coagulase negative Staphylococcus (CoNS) strains. A total of 180 strains of Staphylococcus spp. were isolated from bovine mastitis, dogs with otitis externa and chickens with various infections. The isolates were identified as S. aureus (29.4%), S. hyicus (16.7%), S. intermedius (3.9%), S. chromogenes (16.1%), S. lentus (13.3%), S. epidermidis (11.1%), S. simulans (7.8%) and S. haemolyticus (1.7%). The rate of positiveness for deoxyribonuclease (DNase) …