Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 4 of 4

Full-Text Articles in Medicine and Health Sciences

Treatment Of Periodontitis Affecting Human Primary Teeth—A Systematic Review, Protyusha Guha Biswas, Anusha Mohan, Eswar Kandaswamy Jul 2023

Treatment Of Periodontitis Affecting Human Primary Teeth—A Systematic Review, Protyusha Guha Biswas, Anusha Mohan, Eswar Kandaswamy

School of Dentistry Faculty Publications

The aim of this systematic review is to report the treatment options (Intervention) and outcomes (O) for primary teeth affected by periodontitis (Population) and if the treatment of primary teeth can prevent the spread of periodontitis to permanent teeth (Outcomes). The following databases were searched for papers published before December 2022: PubMed, Embase, Web of Science, and Ebscohost. Studies on children affected by periodontitis involving the primary teeth were included and those on children who presented with periodontitis as a manifestation of systemic disease were excluded. Narrative synthesis and methodological quality assessments were performed for the included studies. Three interventional …


Serum Leptin Levels And Their Proportional Relationship With Pro- And Antiinflammatory Mediators In Aggressive Periodontitis: Preliminary Report, Zuhal Yetki̇n Ay, Recep Sütcü, Havva Koçak, Fatma Yeşi̇m Kirzioğlu Jan 2013

Serum Leptin Levels And Their Proportional Relationship With Pro- And Antiinflammatory Mediators In Aggressive Periodontitis: Preliminary Report, Zuhal Yetki̇n Ay, Recep Sütcü, Havva Koçak, Fatma Yeşi̇m Kirzioğlu

Turkish Journal of Medical Sciences

To investigate the serum level of leptin (OB) and its relationship with pro- and antiinflammatory cytokines/mediators in aggressive periodontitis (AP) patients. Materials and methods: The study population (n = 12) comprised 6 AP patients and 6 periodontally healthy subjects (HC). The fasting venous serum samples were used to determine the OB and the cytokines/mediators belonging to the Th1/Th2/Th17 cells. The correlations among the OB and cytokines/mediators in the serum and clinical periodontal parameters were also investigated. Results: The AP group presented significantly higher serum TGF-\beta1 and IL-2 concentrations (pg/mL) and lower IL-4, IL-5, IL-12, IL-13, and IL-17A concentrations than the …


Frequency Of Tlr-2, 4, 9 And Cd14 Polymorphisms In Aggressive Periodontitis Population In African-Americans, Melanie Chou Jun 2009

Frequency Of Tlr-2, 4, 9 And Cd14 Polymorphisms In Aggressive Periodontitis Population In African-Americans, Melanie Chou

Theses and Dissertations

Aim: The aim of this study is to determine the frequency of single nucleotide polymorphisms (SNPs) in various pattern recognition receptor (PRR) genes, including Toll like receptors (TLR) -2, -4, -9, and CD14 in chronic (CP), localized (LAP) and generalized aggressive (GAP) periodontitis and periodontally healthy (NP) patients in an African American population. Methods: A total of 205 subjects were involved in the study. The LAP group consists of 25 subjects, the GAP group 50 subjects, the CP group 73 subjects and the NP group 57subjects. Genotyping was performed in TLR2 (G2408A), TLR4 (A896G),TLR9 (T1486C) and CD14 (C260T) genes by …


C-Reactive Protein Levels In Generalized Aggressive Periodontitis Patients, Trang Nguyen Salzberg Jan 2004

C-Reactive Protein Levels In Generalized Aggressive Periodontitis Patients, Trang Nguyen Salzberg

Theses and Dissertations

Background: There is mounting evidence to indicate that periodontitis may be a risk factor for cardiovascular disease (CVD). Periodontitis may be linked to CVD as either an etiologic mechanism or a predisposing factor that can hasten disease progression. Proinflammatory cytokines, elevated fibrinogen, and platelet aggregation are all potential mechanisms. The purpose of this study is to compare and review the serological differences in subjects with severe periodontitis, some of which involve established risk factors for atherosclerosis, particularly heightened C-reactive protein levels. Methods: A total of 184 subjects, comprising of two periodontal subgroups, non-periodontal (NP = 91) and generalized aggressive periodontitis …