Medicine and Health Sciences Commons^™

Impact Of Submaximal Versus Supramaximal High-Intensity Interval Training On Blood Glucose Regulation In Type 2 Diabetes Mellitus: A Systematic Review And Meta-Analysis, Jennifer A. Weil, Daryl Lee Parker

International Journal of Exercise Science: Conference Proceedings

High-intensity interval training (HIIT) is an efficient form of exercise that can potentially induce significant and clinically meaningful blood glucose improvements in patients with Type 2 diabetes mellitus (T2DM). It is unknown whether certain HIIT interval intensities may be more effective than others in combating hyperglycemia in T2DM. PURPOSE: The purpose of this study was to determine if submaximal or supramaximal HIIT reduces blood glucose or improves markers of insulin resistance more than the other in T2DM patients using a systematic review and meta-analytical approach. METHODS: Three databases (Embase/MEDLINE, CENTRAL, and PubMed) were systematically searched in July 2021 …

Development Of A Medication Compliance Determinant Instrument For Low-Middle Literate Patients With Type 2 Diabetes Mellitus, Ivans Panduwiguna, Rani Sauriasari, Ratu Ayu Dewi Sartika, Woro Riyadina, Fransiskus Samuel Renaldi

Kesmas

Diabetes, a leading cause of 6.7 million deaths in 2021, poses a significant challenge despite existing interventions. Non-adherence to treatment remains a barrier to diabetes management. However, a comprehensive instrument to assess medication adherence determinants in diabetes patients’ population in Indonesia with low-medium literacy levels and following the sociocultural characteristics of Indonesian society has been lacking. This study aimed to develop and evaluate a valid and reliable instrument for measuring medication adherence in type 2 diabetes mellitus patients based on the Borg and Gall model. Through the input of an expert panel, a valid and reliable instrument was developed, which …

Development Of A Comprehensive Staff Development Program About Outpatient Diabetes Clinic Care For Patients With Type 1 And Type 2 Diabetes Mellitus, Cynthia G. Sanders

Electronic Theses and Dissertations

The purpose of this DNP project was to evaluate if focused staff education about the many aspects of outpatient diabetes care has the potential to increase knowledge and impact attitudes about diabetes in staff providing care to patients with type 1 and type 2 diabetes mellitus. Diabetes is a disease with wide ranging implications, in terms of cost, consumer health, and quality of life, for populations worldwide, including the United States. It is critical that staff who participate in the care of patients with diabetes mellitus have a role-specific educational foundation to support their contribution to patient care. The researcher …

Abo Blood Group Type And The Risks Of Peripheral Artery Disease In Type Ii Diabetes Mellitus, Dedy Pratama, Adi N.D Puruboyo

The New Ropanasuri Journal of Surgery

Introduction. Peripheral artery disease (PAD) is a common complication of diabetes mellitus (DM), affecting up to 20% of people over 65. Blood type is hypothesized to influence PAD, although it has yet to be extensively studied. We aim to investigate the correlation between ABO blood group type and the severity of PAD in patients with type II DM.

Methods. We conducted a cross-sectional study on DM type II patients with PAD at the Cipto Mangunkusumo National Hospital in Indonesia between January 2022 to June 2022. PAD was diagnosed based on the ankle-brachial index (ABI) measurement. The PAD severity was grouped …

Quality Of Glycemic Control In Type 2 Diabetes Mellitus (T2dm) And Its Association With Markers Of Coagulation And Inhibitors Of Fibrinolysis: A Case–Control Study In The Upper West Region, Ghana, Peter K. Selleh, Enoch O. Anto, Wina I. O. Boadu, Benedict Sackey, Lilian A. Boateng, Charles Nkansah, Frederick Nsafoah, Abdul R. Saasi, Selina Mintaah, Yaw A. Wiafe, Charles Derigubah, Emmanuel E. Korsah, Joseph Frimpong, Ezekiel Ansah, Valentine C. K. T. Tamakloe, Patrick Adu, Joseph Boachie, Otchere Addai-Mensah

Research outputs 2022 to 2026

Background and Aims: Type 2 diabetes mellitus (T2DM) individuals are at a higher risk of developing diabetes complications, with approximately 80% complication-related mortality. The increased morbidity and mortality among T2DM patients are partly due to dysregulated hemostasis. This study determined the quality of glycemic control in T2DM and its association with markers of coagulation and inhibitors of fibrinolysis. Methods: This case–control study recruited 90 participants involving: 30 T2DM patients with good glycemic control, 30 with poor glycemic control, and 30 nondiabetic subjects as controls at a Municipal Hospital in Ghana. Fasting blood glucose, glycated hemoglobin, activated partial thromboplastin time (APTT), …

The Intensity Of Free Radical Processes And Chaperone Activity In The Saliva Of Patients With Type 2 Diabetes, Anna A. Cheprasova, Sergey S. Popov, Alexander N. Pashkov, Aleksei N. Verevkin, Valentina O. Mittova, Konstantin K. Shulgin

BioMedicine

Introduction: Saliva is a clinically informative biological fluid that contains many biomarkers, allowing multiple analyses to be performed. Aim: The objectives of this study were the assessment of the serum and saliva levels of biochemical parameters and intensity of free radical processes in T2DM patients and the identification of the correlation between certain criteria. Methods: This case-control study included 40 T2DM patients, which were compared with 40 healthy individuals. The levels of glucose, cholesterol triglycerides, total protein, diene conjugates, and chaperone activity were measured using the spectrophotometric method. The concentration of 8-oxo-2'-deoxyguanosine was assessed by competitive enzyme-linked immunosorbent assay. Results: …

Telehealth And Its Impact On The Management Of Type 2 Diabetes Mellitus, Melissa N. Toulios

Evidence-Based Practice Project Reports

Diabetes mellitus type 2 (T2DM) is a growing epidemic that affects millions of people throughout the world. The recent COVID-19 pandemic has created many new challenges, including access to health care for treatment of chronic diseases, such as diabetes (Robson & Hosseinzadeh, 2021). Telehealth has offered a promising approach to improve the management of diabetes(Bellman, 2021). People with diabetes are less likely to manage their diabetes through the usual care because of risk of contracting COVID-19 (CDC, 2022). The purpose of this EBP project was to evaluate the effectiveness of T2DM management through a telehealth approach. This project has addressed …

A Prescription For Diabetes Self-Management Education: Best Practice For Persons With Type Ii Diabetes Mellitus, Ashley J. Milcarek

Evidence-Based Practice Project Reports

Diabetes self-management education and support (DSMES) programs have been shown to improve patient outcomes and lower hemoglobin A1c (Hgb A1c) levels in those who are diagnosed with type two diabetes mellitus (T2DM). However, these programs are often underutilized and have low referral rates, despite the known benefits (Powers et al., 2020). The purpose of this patient-centered EBP project was to evaluate the effectiveness of a patient-driven questionnaire, completed by patients with T2DM during routine office visits, in increasing the percentage of patients referred to DSMES by their provider. Specifically, this project addressed the following PICOT question: In adults who have …

Metformin-Associated Lactic Acidosis: A Case Report, Joshua Santoli, Jamie Lee Aldakkour, Hossein Tohidi, Yizhi Lin

HCA Healthcare Journal of Medicine

Introduction

Metformin is considered a first-line therapy for patients with diabetes secondary to its cost efficiency, minimal side effects, and marked improvement in one’s hemoglobin A1c; however, metformin is avoided in patients with renal insufficiency out of concern for drug accumulation and lactic acidosis. In fact, there is a black box warning for metformin, identifying lactic acidosis as the inciting trigger for fatal arrhythmias and death.

Case Presentation

A 62-year-old male presented with multiple episodes of nausea, vomiting, abdominal pain, and decreased urine output for 3 days after working on a roof, all day in the summer heat. He did …

A Case Of Unilateral Jerking Movements In A Patient With Uncontrolled Type 2 Diabetes Mellitus, Mark Cheneler, Tapannita Padhi, Khizir Qureshi, Carlos Bahrami

North Texas GME Research Forum 2023

Hemichorea-hemiballismus (HCHB) syndrome is a syndrome characterized by choreic movements which are irregular, nonrepetitive, and random movements and ballismus which are spontaneous, violent movements. HCHB syndrome is a rare presentation which can be precipitated by uncontrolled diabetes and is thought to have multiple plausible mechanisms. One mechanism of HCHB with uncontrolled diabetes is ischemic injury in the basal ganglia causing impaired gross motor control. Presented here is a case of HCHB syndrome initially seen on imaging and later correlated with physical examination. This patient presented for nonspecific complaints of fatigue, generalized weakness, and lower extremity weakness. On evaluation by EMS …

Risk Factor Analysis Of Hospital Readmissions At St. Petersburg General Hospital, Vincent Wu, Sean Quinonez, My Myers, Kyle Borodunovich, Aisha Shamsi, Patrick Stocker, Bryan Fink, Steven Ferreira

HCA Healthcare Journal of Medicine

Background

Decreased readmission rates are largely seen as an indicator of effective care and improved resource management. The case management team at St. Petersburg General Hospital in St. Petersburg, Florida identified chronic obstructive pulmonary disease (COPD) exacerbation, pneumonia, and sepsis as 3 of the leading diagnoses on index admission that later led to 30-day readmissions. By examining patients with these 3 diagnoses on index admission, we decided to investigate potential readmission risk factors including patient age, sex, race, body mass index (BMI), length of stay during the index admission, insurance type during index admission, discharge placement after index admission, coronary …

Impact Of Perioperative Dexamethasone On Hospital Length Of Stay And Glycemic Control In Patients With Type 2 Diabetes Undergoing Total Hip Arthroplasty, Vanessa Williams, Mohammad J. Uddin Ansari, Amruta Jaju, Stacey Ward, Daniel O'Keefe, Jumana Abdelkarim, Nicole Montes, Ula Tarabichi, Albert Botchway, Michael G. Jakoby Iv

Journal of Patient-Centered Research and Reviews

Purpose: This study aimed to evaluate effects of perioperative dexamethasone on hospital length of stay (LOS) and glycemic control for patients with type 2 diabetes mellitus undergoing total hip arthroplasty (THA).

Methods: We performed retrospective case review of THA performed in adults (≥ 18 years old) with type 2 diabetes at Springfield Memorial Hospital (Springfield, IL) immediately before (2013), during (2014), and after (2015) publication of consensus guidelines for use of perioperative dexamethasone. Hospital LOS was the primary endpoint. Capillary blood glucose by hospital day, proportion of patients treated with insulin, and median insulin dose by hospital day …

Association Of Igg N-Glycomics With Prevalent And Incident Type 2 Diabetes Mellitus From The Paradigm Of Predictive, Preventive, And Personalized Medicine Standpoint, Xiaoni Meng, Fei Wang, Xiangyang Gao, Biyan Wang, Xizhu Xu, Youxin Wang, Wei Wang, Qiang Zeng

Research outputs 2022 to 2026

Objectives:

Type 2 diabetes mellitus (T2DM), a major metabolic disorder, is expanding at a rapidly rising worldwide prevalence and has emerged as one of the most common chronic diseases. Suboptimal health status (SHS) is considered a reversible intermediate state between health and diagnosable disease. We hypothesized that the time frame between the onset of SHS and the clinical manifestation of T2DM is the operational area for the application of reliable risk assessment tools, such as immunoglobulin G (IgG) N-glycans. From the viewpoint of predictive, preventive, and personalized medicine (PPPM/3PM), the early detection of SHS and dynamic monitoring by glycan biomarkers …

Vitamin K-1 Intake And Incident Diabetes In The Danish Diet, Cancer, And Health Study, Pratik Pokharel, Jamie W. Bellinge, Frederik Dalgaard, Kevin Murray, Marc Sim, Bu B. Yeap, Emma Connolly, Lauren C. Blekkenhorst, Catherine P. Bondonno, Joshua R. Lewis, Gunnar Gislason, Anne Tjønneland, Kim Overvad, Jonathan M. Hodgson, Carl Schultz, Nicola P. Bondonno

Research outputs 2022 to 2026

Context: Observational studies have reported lower risks of type 2 diabetes with higher vitamin K1 intake, but these studies overlook effect modification due to known diabetes risk factors. Objective: To identify subgroups that might benefit from vitamin K1 intake, we examined associations between vitamin K1 intake and incident diabetes overall and in subpopulations at risk of diabetes. Methods: Participants from the prospective cohort, the Danish Diet, Cancer, and Health Study, with no history of diabetes were followed up for diabetes incidence. The association between intake of vitamin K1, estimated from a food frequency questionnaire completed at baseline, and incident diabetes …

The Effect Of Regular Consumption Of Reformulated Breads On Glycemic Control: A Systematic Review And Meta-Analysis Of Randomized Clinical Trials, Alena M. Schadow, Ingrid Revheim, Ulrike Spielau, Jutta Dierkes, Lukas Schwingshackl, Jan Frank, Jonathan M. Hodgson, André Moreira-Rosário, Chris J. Seal, Anette E. Buyken, Hanne Rosendahl-Riise

Research outputs 2022 to 2026

Bread is a major source of grain-derived carbohydrates worldwide. High intakes of refined grains, low in dietary fiber and high in glycemic index, are linked with increased risk for type 2 diabetes mellitus (T2DM) and other chronic diseases. Hence, improvements in the composition of bread could influence population health. This systematic review evaluated the effect of regular consumption of reformulated breads on glycemic control among healthy adults, adults at cardiometabolic risk or with manifest T2DM. A literature search was performed using MEDLINE, Embase, Web of Science and the Cochrane Central Register of Controlled Trials. Eligible studies employed a bread intervention …