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An Assessment Of Primary Care Physician Opinions About Supporting The Independent Autonomous Practice By Advanced Practice Nurses, James Michael Flanigan Dec 2015

An Assessment Of Primary Care Physician Opinions About Supporting The Independent Autonomous Practice By Advanced Practice Nurses, James Michael Flanigan

Graduate Theses and Dissertations

The Affordable Care Act (ACA) changed the national discussion about who is the decision-maker in healthcare delivery – physicians or others that pay the bill. The federal government is the largest payer of healthcare services while states are responsible for implementing the ACA’s features. Through the ACA, the federal government endorsed non-physician primary care by advanced practice registered nurses (APRN). The research question of this study is: Why do some primary care physicians support independent autonomous practice for advanced practice registered nurses while others do not? The research question should be important to policy-makers because physicians are the predominate purchasers …


The Efficacy Of An Eight-Week Undergraduate Course In Resilience, Asher J. Morgan Dec 2015

The Efficacy Of An Eight-Week Undergraduate Course In Resilience, Asher J. Morgan

Graduate Theses and Dissertations

The purpose of this research was to measure the efficacy of an 8-week undergraduate

course in resilience. Finding useful strategies to understand how college students manage stress

and adversity is important to college administrators. The main topics that were assessed were

resilience, well-being, and assertiveness. Participants for this study included undergraduate

students enrolled either in a 8-week course on Resilience or a Public Health course. The

Connor-Davidson Resilience Scale, Questionnaire for Eudaimonic Well-Being, and the Simple

Rathus Assertiveness Scale were used to determine the efficacy of the 8-week course. Overall,

there was not a significant difference in resilience and well-being, …


Community-Based Rehabilitation Supports For Social Inclusion And Work Participation Of Young Adults With Visual Impairment In Kenya: A Case Study, Philomena Jepkemboi Tanui Dec 2015

Community-Based Rehabilitation Supports For Social Inclusion And Work Participation Of Young Adults With Visual Impairment In Kenya: A Case Study, Philomena Jepkemboi Tanui

Graduate Theses and Dissertations

Young adults with a visual impairment (VI) experience less interaction with the community that impacts the way they relate to the world as they transition to the larger society where they face significant barriers of adjustment, exclusion, and work participation. Young adults with VI contend with cultural stigma, inequality, poor self-esteem caused by marginalization, a low quality of life (QOL), and lack of Social support systems that exist beyond the home. The aim of this study was to understand the perceptions of young adults with VI in Elgeyo-Marakwet and Kisumu Counties of Kenya concerning the barriers to community inclusion and …


A Community-Based Participatory Approach To Understanding Health Beliefs, Policies, Barriers, And Solutions Related To The Health Disparities Of Marshallese Cofa Migrants In Arkansas., Pearl Anna Mcelfish Dec 2015

A Community-Based Participatory Approach To Understanding Health Beliefs, Policies, Barriers, And Solutions Related To The Health Disparities Of Marshallese Cofa Migrants In Arkansas., Pearl Anna Mcelfish

Graduate Theses and Dissertations

Public policies have different effects on different populations groups and can perpetuate health disparities among some populations. My research utilizes community-based participatory approach to research in the examination of one unique population: the Marshallese. This dissertation research presents three papers that are part of a cohesive research agenda predicated on community-based participatory research (CBPR) to facilitate policy-oriented learning. My research can be used to inform health policy, health care services, and health education. Chapter Two presents the article titled: Health Beliefs of US Marshallese Regarding Type 2 Diabetes.

This article explores the research question: what health beliefs related to diabetes …


Reduction Of Campylobacter Jejuni On Chicken Wingettes By Treatment With Caprylic Acid, Chitosan Or Protective Cultures Of Lactobacillus Spp., Ann Nicole Woo-Ming Dec 2015

Reduction Of Campylobacter Jejuni On Chicken Wingettes By Treatment With Caprylic Acid, Chitosan Or Protective Cultures Of Lactobacillus Spp., Ann Nicole Woo-Ming

Graduate Theses and Dissertations

Poultry is one of the main sources of protein in the United States and in 2014 Americans ate approximately 100 lbs per person. However, consumption of poultry products is strongly associated with foodborne illness from Campylobacter. In the first study, chitosan, caprylic acid and their combination were evaluated as a coating treatment for the reduction of Campylobacter jejuni on poultry products. For the initial screening trials, chitosan of three different molecular weights (15-50 kDa, 190-310 kDa and 400-600 kDa) was evaluated at three concentrations (0.5%, 1.0%, 2.0%) and separately, caprylic acid was tested at 0.5%, 1.0% and 2.0% using chicken …


A Descriptive Case Study Of Individuals With Presumed Ocular Histoplasmosis Syndrome Utilizing A Facebook Support Group, Lisa Aimee Thompson Dec 2015

A Descriptive Case Study Of Individuals With Presumed Ocular Histoplasmosis Syndrome Utilizing A Facebook Support Group, Lisa Aimee Thompson

Graduate Theses and Dissertations

This dissertation describes the experiences of people diagnosed with presumed ocular histoplasmosis syndrome as they participate in an online peer-support group on Facebook. This is a descriptive case study of factors related to adjustment, treatment, emotional distress, access to services, and online peer support. Participants were interviewed and observed, and documents were collected to describe this phenomenon.


Investigations Into The Cross-Infectivity Of Nematode Parasites Of Cattle And Sheep, Eva Marie Wray Dec 2015

Investigations Into The Cross-Infectivity Of Nematode Parasites Of Cattle And Sheep, Eva Marie Wray

Graduate Theses and Dissertations

The existence of anthelmintic resistance is not singular in parasite species, host species or geographic region. It has become a problem of worldly stature, especially when considering sheep nematodes. Recommendations have been modified from chemical-based control to multipart, managerial intervention. Compared with nematodes of cattle, the worldwide resistance of sheep nematodes to anthelmintic remedies is much more pronounced and urgent. As the resistance to essentially all anthelmintic classes approaches a cautionary level, the implementation of non-chemical controls has grown increasingly essential. Six-6 to 8 month old Holstein steer calves, six-5 month old Katahdin ram lambs and eight-5 month old Suffolk …


Evaluation Of Bacillus Spp Candidates For Aflatoxin B1 Biodegradation In Broiler Chickens, Rosario Galarza Seeber Dec 2015

Evaluation Of Bacillus Spp Candidates For Aflatoxin B1 Biodegradation In Broiler Chickens, Rosario Galarza Seeber

Graduate Theses and Dissertations

Poultry health has been traditionally maintained by hygenic measures, vaccinations, and the use of antibiotics. Modern husbandry management considers the use of probiotics as a natural way to protect birds against many everyday pathogens. Different strains of Bacillus spp. have proved to have beneficial effects in poultry production. However, the most used bacterium in commercial probiotics is Lactobacillus, a vegetative cell. In contrast, Bacillus spp are bacterial spores, highly resistant to harsh conditions, which makes them preferable, in some cases, to Lactobacillus because of shelf life and storage conditions. There is published information regarding mycotoxin detoxification by bacteria. Mycotoxins are …


Preventive Maintenance Decision Modeling In Health And Service Systems, Mahboubeh Madadi Jul 2015

Preventive Maintenance Decision Modeling In Health And Service Systems, Mahboubeh Madadi

Graduate Theses and Dissertations

This dissertation focuses on the preventive maintenance decision modeling in healthcare and service systems. In the first part of this dissertation, some issues in preventive health decisions for breast cancer are addressed, and in the second part, the required characteristics for preventive maintenance of an unreliable queuing system are derived.

Adherence to cancer screening is the first issue that is addressed in this dissertation. Women’s adherence or compliance with mammography screening remained low in the recent years. In this dissertation, we first develop a design-based logistic regression model to quantify the probability of adherence to screening schedules based on women’s …


Understanding Technology Diffusion And Spatial Accessibility In The Home Healthcare Industry, Mehmet Serdar Kilinç Jul 2015

Understanding Technology Diffusion And Spatial Accessibility In The Home Healthcare Industry, Mehmet Serdar Kilinç

Graduate Theses and Dissertations

Home healthcare is becoming an important alternative to institutionalized care. It not only reduces costs but also increases health outcomes and patient satisfaction. However, the availability and efficiency of home healthcare services need to be improved as the aging population increases in the US. Hence, understanding home healthcare utilization and access are the essential steps to develop strategies ensuring effective and sustainable services to patients.

This research aims to study two main issues in the US home healthcare system: diffusion and long-term impacts of home telehealth and potential spatial accessibility of home healthcare services. Home telehealth is a promising technology …


Socially Constructing Drug Addicts From The Poor: A Critical Discourse Analysis, Kalynn Susan Amundson Jul 2015

Socially Constructing Drug Addicts From The Poor: A Critical Discourse Analysis, Kalynn Susan Amundson

Graduate Theses and Dissertations

Welfare drug testing was authorized by the Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) of 1996, and has subsequently garnered extensive legislative interest in numerous states. This policy raises several questions, which are the subjects of the two journal articles and one manuscript included in this dissertation.

The first article addresses the question of a possible confluence of War on Drugs and Welfare Reform policies as evidenced through welfare drug testing policy, and indicated by continuity in policymakers’ rhetoric. This study examines federal-level policymakers’ debate discourse in these two policy streams. The analysis finds themes of the Social pathology, …


Development And Preliminary Validation Of A Nonmedical Prescription Drug Motives Questionnaire, Lauren Ashleigh Milner Jul 2015

Development And Preliminary Validation Of A Nonmedical Prescription Drug Motives Questionnaire, Lauren Ashleigh Milner

Graduate Theses and Dissertations

The prevalence of nonmedical prescription drug (NMPD) use continues to increase among emerging adult populations; however, little is known about the motivations behind this use. The current study aimed to extend previous research by developing and validating the first known comprehensive NMPD motives measure. As such, the primary focus of the current study was to examine evidence for the reliability and validity of the NMPD Motives Questionnaire by assessing the factor structure, internal consistency, and construct validity of the motives scale. Participants were drawn from a larger study of college student substance use behaviors and attitudes (N = 1,427; Mage= …


Shiga Toxin-Producing Escherichia Coli (Stec) Detection Strategies With Formalin-Fixed Stec Cells, Christopher Adam Baker Jul 2015

Shiga Toxin-Producing Escherichia Coli (Stec) Detection Strategies With Formalin-Fixed Stec Cells, Christopher Adam Baker

Graduate Theses and Dissertations

Certain pathogenic Escherichia coli known as Shiga toxin (Stx)-producing Escherichia coli (STEC) are commensals in cattle, and typically cause bloody diarrhea in humans once the Stx toxin is secreted in invaded intestinal epithelial cells. Infections with STEC cells can lead to hemolytic uremic syndrome, which is commonly associated with kidney failure. Several STEC serogroups have been declared adulterants in raw, non-intact ground meat, and future regulations could potentially lead to a higher number of STEC serogroup detection strategies for these pathogenic microorganisms. Microbiological research laboratories may benefit from formalin-fixed STEC cells for periodic (daily, weekly, monthly, among others) instrument validation/calibration …


Numerical Simulation Of Terahertz Wave Interaction With Breast Cancer Tumor Tissue Sections, Abayomi Omotola Omolewu Jul 2015

Numerical Simulation Of Terahertz Wave Interaction With Breast Cancer Tumor Tissue Sections, Abayomi Omotola Omolewu

Graduate Theses and Dissertations

This thesis presents numerical simulation of terahertz (THz) wave interaction with breast cancer tumor tissue sections. The obtained results are expressed in THz images of heterogeneous material that mimics the excised breast cancer tissue sections. The finite-element software package ANSYS High Frequency Structural Simulator (HFSS) was used in this work. HFSS is a full wave frequency domain three-dimensional (3D) electromagnetic simulation package. In this work, four breast cancer tissue models based on pathology images were simulated and images of the models were obtained at 1 THz. An incident Gaussian beam was raster scanned over tissue model configurations and the reflected …


Students' Perspectives After Participation In A Mandated College Level Alcohol Intervention Program: A Phenomenological Study, Suzanna L. Guizar Jul 2015

Students' Perspectives After Participation In A Mandated College Level Alcohol Intervention Program: A Phenomenological Study, Suzanna L. Guizar

Graduate Theses and Dissertations

Alcohol abuse among college students continues to be a significant problem by which the consequences impact the student, their peers, and the university. Although quantitative research with volunteer participants supports the use of enhanced brief motivational interventions and cognitive behavioral skills training in reducing risky drinking behavior (binge drinking), research with mandated students has shown inconsistent findings. The current study is a phenomenological qualitative study exploring the students’ perspectives after attending a mandated college-level alcohol intervention program. Mandated students are students who have been referred to an alcohol intervention as a result of violating an alcohol related policy on campus. …


The Effects Of Alcohol On The Interpretation Of Social And Emotional Cues: A Field Study Of College Student Drinking, Emotion Recognition, And Perceptions Of A Hypothetical Sexual Assault, Alexander James Melkonian Jul 2015

The Effects Of Alcohol On The Interpretation Of Social And Emotional Cues: A Field Study Of College Student Drinking, Emotion Recognition, And Perceptions Of A Hypothetical Sexual Assault, Alexander James Melkonian

Graduate Theses and Dissertations

Alcohol use and abuse among emerging adults is highly correlated with increased risk for sexual victimization. Alcohol myopia theory has been used to explain impairments in Social information processing resulting in decreased attention to environmental Social cues including risk factors for sexual assault as well as facial emotional recognition. Those with deficits in Social information processing may be at particular risk for the misperception of salient risk factors for sexual assault by victims, perpetrators, and bystanders when intoxicated. In this naturalistic field study, participants who had been consuming alcohol were recruited to engage in tasks of facial emotion recognition and …


Is The Geriatric Impact Ipad Test A Valid Measurement Of Cognitive Function In Older Adults?, Heather Elise O'Dell Jul 2015

Is The Geriatric Impact Ipad Test A Valid Measurement Of Cognitive Function In Older Adults?, Heather Elise O'Dell

Graduate Theses and Dissertations

The number of older adults will rapidly increase within the next generation (Brookmeyer, Johnson, Ziegler-Graham, & Arrighi, 2007). Alzheimer’s disease risk increases with age, especially after age 60 (NIA, n.d.). Aging leads to a decrease in functional independence, and this side effect is exacerbated by cognitive decline (Johnson, Lui, & Yaffe, 2007). Executive function is a predictor of Alzheimer’s disease onset and progression (Zhang, Han, Verhaeghen, & Nilsson, 2007). The Geriatric ImPACTTM test is a potential new and more convenient testing methods than traditional methods used. The purpose of this research is to validate the Geriatric ImPACTTM test by comparing …


Investigating The Theory Of Ambiguous Loss: The Role Of Ambiguity Tolerance In Pre-Death Grief For Caregivers Of Individuals With Dementia, Megan Kale-Cheever May 2015

Investigating The Theory Of Ambiguous Loss: The Role Of Ambiguity Tolerance In Pre-Death Grief For Caregivers Of Individuals With Dementia, Megan Kale-Cheever

Graduate Theses and Dissertations

This thesis sought to investigate the relationship between ambiguity tolerance and caregiver grief within the framework of ambiguous loss theory. Thirty-one family caregivers completed a quantitative survey comprising two pre-existing scales and several demographic questions designed to assess level of ambiguity tolerance, level of grief, caregiver age and gender, type of relationship to the care recipient, living situation, length of caregiving career, level of Social support and frequency of difficult behaviors. Quantitative data analysis revealed that while no relationship existed between total ambiguity tolerance and total caregiver grief, a modest, inverse relationship exists between tolerance toward general-type ambiguity and burden, …


The Production Of Biobutanol From Biomass Via A Hybrid Biological/Chemical Process, Thomas Melvin Potts May 2015

The Production Of Biobutanol From Biomass Via A Hybrid Biological/Chemical Process, Thomas Melvin Potts

Graduate Theses and Dissertations

Biobutanol use as a fuel began in the late 19th century. Problems remain in economic viability. A review of the state of the art and need for technical advances is presented.

The technical potential of producing biofuel from a naturally occurring macroalgae was studied. The algae grow in Jamaica Bay, New York City, in contaminated water. The process consisted of mechanical harvesting, drying, grinding, and acid hydrolysis to form an algal sugar solution. Clostridium beijerinckii and C. saccharoperbutylacetonicum were used in an acetone butanol ethanol (ABE) fermentation to make butanol. Fermentation was followed by distillation Butanol concentrations during fermentation reached …


Effects Of Mild Hypohydration And Hyperthermia On Cognition And Mood In Obese And Non-Obese Females, Jenna Marie Burchfield May 2015

Effects Of Mild Hypohydration And Hyperthermia On Cognition And Mood In Obese And Non-Obese Females, Jenna Marie Burchfield

Graduate Theses and Dissertations

INTRODUCTION: Information regarding effects of hypohydration (HY) and hyperthermia (HT) on cognition, mood and development of symptoms is conflicting since the two conditions often confound each other. Further, although obese individuals may have physiological impairments during heat stress, whether psychological impairments occur with HY and HT is unknown. PURPOSE: To assess the independent and combined effects of mild HY and HT on cognition, mood, and the development of symptoms in obese and non-obese females. METHODS: Twenty-two healthy females (11 non-obese, 22±2y, 61±6kg, 25±4% body fat; 11 obese, 22±2y, 80±18kg, 44±5% body fat) volunteered in two randomized, repeated-measures trials, involving passive …


Reporting Practices, Knowledge And Opinion Of Policy Regarding Drivers With Dementia Among Arkansas Neurologists And Geriatricians, Erika Martin Gergerich May 2015

Reporting Practices, Knowledge And Opinion Of Policy Regarding Drivers With Dementia Among Arkansas Neurologists And Geriatricians, Erika Martin Gergerich

Graduate Theses and Dissertations

Background: States have various policies regarding a physician's ability or responsibility to report at-risk drivers with dementia to the Department of Motor Vehicles (DMV). Some states have mandatory reporting policies, others have optional reporting policies and some have no policy regarding this issue. Arkansas has no reporting policy regarding drivers with dementia to the DMV. Therefore, physicians in Arkansas face the risk of liability if they report a patient against their will to the DMV in good faith. Neurologists and geriatricians are often in a position to diagnose and treat individuals with dementia. Research Questions: The following three research questions …


The Role Of Stress: Low Birth Weight And Preterm Birth For African American Women, Tionna Latrice Jenkins May 2015

The Role Of Stress: Low Birth Weight And Preterm Birth For African American Women, Tionna Latrice Jenkins

Graduate Theses and Dissertations

This population-based study evaluates the impact that psychoSocial stress has on adverse birth outcomes of low birth weight (LBW) and pre-term birth (PTB) among African American mothers in Arkansas. The relationship between adverse birth outcomes in African American women and stress in comparison to non-Hispanic Caucasian women data was evaluated from the Pregnancy Risk Assessment Monitoring System (PRAMS) quantitative survey. Data from 2005 through 2010 was reviewed to show the impact that psychoSocial stress has on adverse birth outcomes. The study sample was comprised of 14,196 participants.

Ethnic group status is the key maternal-level independent variable in this study. Of …


An Examination Of Psychoeducation And Its Potential Modifying Influence On Alcohol Use Patterns Among Adults Reporting Co-Occurring Posttraumatic Stress Symptoms And Hazardous Alcohol Consumption, Sarah Jo Bujarski May 2015

An Examination Of Psychoeducation And Its Potential Modifying Influence On Alcohol Use Patterns Among Adults Reporting Co-Occurring Posttraumatic Stress Symptoms And Hazardous Alcohol Consumption, Sarah Jo Bujarski

Graduate Theses and Dissertations

Research has suggested that consumption of alcohol in the presence of elevated posttraumatic stress symptom (PTSS) may serve an avoidant function to cope with negative emotions. These coping-related motives for use are theorized to both maintain PTSS and relate to poorer prognoses in treatment for alcohol use disorders (AUDs). Treatments utilizing coping skills training, which typically also involves educating clients about the negative consequences of drinking alcohol to cope, suggest the utility of targeting coping behaviors to reduce alcohol use. These studies, however, have not attempted to isolate the effects of psychoeducation on alcohol-related factors. The current study investigated the …


The Effect Of Balance-Based Torso-Weighting On Mobility, Gait, Balance, Postural Control, And Falls Efficacy In Mobility Limited Older Adults, Jennifer L. Vincenzo May 2015

The Effect Of Balance-Based Torso-Weighting On Mobility, Gait, Balance, Postural Control, And Falls Efficacy In Mobility Limited Older Adults, Jennifer L. Vincenzo

Graduate Theses and Dissertations

Exercise is a known intervention to prevent fall risk among older adults; however, adherence is poor. Therefore, it is of interest to determine if other interventions improve function and decrease fall risk among older adults. Balance-Based Torso-Weighting (BBTW) is a non-exercise intervention that improves functional measures among adults with multiple sclerosis, yet the effectiveness of BBTW has not been assessed among older adults without progressive neurological disorders. We conducted a double-blind, randomized study to analyze the effect of BBTW on functional measures and falls efficacy among community-dwelling, mobility limited older adults after 5 days of wearing BalanceWear® for 4 hours …


The Role Of Attention In Ego-Depletion, Garrett Pollert May 2015

The Role Of Attention In Ego-Depletion, Garrett Pollert

Graduate Theses and Dissertations

The resource model of ego-depletion is unable to account for the results of several ego-depletion studies, whereas a recent mechanistic revision by Inzlicht and Schmeichel (2012) has focused on the role of attention and motivation in an effort to explain the phenomenon. Assessment of attention's role in restrained and unrestrained eaters may provide evidence that motivation and attention work in tandem to affect one's ability to exert self-control. In this experiment, college-aged females participated in two studies to examine the role of attention in ego-depletion effects. Study 1 evaluated the effect of ego depletion on attention via a dot probe …


Emr Training Tactics: A Case Study Of Clinical Staff Training Experiences, Needs And Perceptions, Victoria Leaann Miller May 2015

Emr Training Tactics: A Case Study Of Clinical Staff Training Experiences, Needs And Perceptions, Victoria Leaann Miller

Graduate Theses and Dissertations

Electronic medical record systems have become essential for giving patient care at health care institutions. The purpose of this study was to explore the training provided to staff at the University of Arkansas for Medical Sciences Northwest Family Medical Center in an effort to identify participant training experiences, needs, and perceptions. This study included qualitative, case study research. There were fourteen participants in the study. A focus group interview was conducted with eight administrative and training participants. Interviews and observations were conducted with six staff members.

The literature review of this study discussed educational theories including andragogy and training techniques. …


Investigations Into The Incidence And Control Of Selected Parasites And Pathogens Which Infect Arkansas Horses, Stephanie Ann O'Berg Rainbolt May 2015

Investigations Into The Incidence And Control Of Selected Parasites And Pathogens Which Infect Arkansas Horses, Stephanie Ann O'Berg Rainbolt

Graduate Theses and Dissertations

Parasite control is an important aspect of health management of horses, particularly the control of gastrointestinal (GI) parasites. Recently, treatment recommendations have involved selective use of anthelmintics in horses with fecal egg counts (FEC) greater than a specified threshold. The objectives of this study were; (1) to determine the prevalence of helminths in our area by egg and L3 determinations, (2) to determine if certain horses maintained low FEC, therefore eliminating the need to treat them on a year-round basis and (3) to determine the effectiveness of four common treatments (moxidectin, ivermectin (pioneer and generic), fenbendazole and pyrantel tartrate) via …


Assessing Vocabulary Of Children: Investigating The Evaluation And Instruction Of Basic Concepts, Rebecca Elizabeth Smith May 2015

Assessing Vocabulary Of Children: Investigating The Evaluation And Instruction Of Basic Concepts, Rebecca Elizabeth Smith

Graduate Theses and Dissertations

Vocabulary knowledge of preschool children is a key factor in predicting literacy success in elementary school (Hammer, Farkas, & Maczuga, 2010). However, few deliberate attempts to teach basic concept vocabulary have been studied (Bowers & Schwarz, 2013; Wilson, 2004). The purpose of this research is to determine if large group explicit instruction with interactive activities of specific basic concept vocabulary will increase preschool children's understanding of basic concept terms when measured by a standardized basic concept assessment. This research will also assess the validity of a basic concept-curriculum based measure (BC-CBM) as an efficient tool to monitor a child's understanding …


Intestinal Inflammation Model Inducing Gut Leakage By Different Methods In Broiler Chickens Using Fitc-D As A Marker, Eduardo Vicuna May 2015

Intestinal Inflammation Model Inducing Gut Leakage By Different Methods In Broiler Chickens Using Fitc-D As A Marker, Eduardo Vicuna

Graduate Theses and Dissertations

Traditionally, antibiotic growth promoters (AGP) have been used in food animals to reduce enteric inflammation and maintain intestinal homeostasis, thus improving performance. Due to increasing restrictions regarding the use of AGP, precise and high throughput enteric inflammation models and markers to search for effective alternatives are urgently needed. Oral administration of fluorescein isothiocyanate dextran (FITC-d) and its passage into blood can be used as a marker for tight junction permeability. FITC-d is a large molecule (3-5 kDa) which does not usually leak through the intact gastrointestinal tract barrier. However, when conditions disrupt the tight junctions between epithelial cells, the FITC-d …


The Paleoepidemiology Of Malaria In The Ancient Near East, Nicole Elizabeth Smith May 2015

The Paleoepidemiology Of Malaria In The Ancient Near East, Nicole Elizabeth Smith

Graduate Theses and Dissertations

The end of the Late Bronze Age in the Near East (1300 - 1200 BCE) saw the widespread collapse of several large cultural centers, the reasons for which are a subject of continued debate. Evidence from events leading up to this cultural collapse suggest epidemic disease may have factored into the eventual downfall of these early civilizations. Recent DNA analysis from Egyptian mummies who lived during the period leading up to the Late Bronze Age collapse identified malaria in several elite individuals, suggesting the widespread prevalence of this infectious disease in Egypt. However, the exact prevalence, antiquity, and dynamics of …