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Full-Text Articles in Medicine and Health Sciences

The Epidemic In Your Medicine Chest, Jeffrey D. Lewis Oct 2013

The Epidemic In Your Medicine Chest, Jeffrey D. Lewis

Pharmacy Practice Faculty Publications

No abstract provided.


Substance Abuse Via Legally Prescribed Drugs: The Case Of Vicodin In The United States, Wendy K. Caldwell, Benjamin Freedman, Luke Settles, Michael M. Thomas, Anarina Murillo, Erika Camacho, Stephen Wirkus Jul 2013

Substance Abuse Via Legally Prescribed Drugs: The Case Of Vicodin In The United States, Wendy K. Caldwell, Benjamin Freedman, Luke Settles, Michael M. Thomas, Anarina Murillo, Erika Camacho, Stephen Wirkus

Faculty Articles

Vicodin is the most commonly prescribed pain reliever in the United States. Research indicates that there are two million people who are currently abusing Vicodin, and the majority of those who abuse Vicodin were initially exposed to it via prescription. Our goal is to determine the most effective strategies for reducing the overall population of Vicodin abusers. More specifically, we focus on whether prevention methods aimed at educating doctors and patients on the potential for drug abuse or treatment methods implemented after a person abuses Vicodin will have a greater overall impact. We consider one linear and two non-linear compartmental …


Carter, Tim Lee, 1910-1987 (Mss 80), Manuscripts & Folklife Archives May 2013

Carter, Tim Lee, 1910-1987 (Mss 80), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid only for Manuscripts Collection 80. Correspondence, photographs, audiotapes, film, clippings, general office files, and records of legislative proceedings relating to the political career of Tim Lee Carter, U.S. Representative (Republican) for Kentucky's Fifth Congressional District, 1965-1981.


Investigating The Main Effects And Interactions Of Induced Mood And Emotional Urgency On Self-Report Cannabis Craving And Consumption, Joseph Anthony De Leo Jan 2013

Investigating The Main Effects And Interactions Of Induced Mood And Emotional Urgency On Self-Report Cannabis Craving And Consumption, Joseph Anthony De Leo

Legacy Theses & Dissertations (2009 - 2024)

The current research investigates the role of induced mood states and emotional urgency - a mood-based facet of impulsivity, on cannabis use behaviors. Specifically, this research aims to extend previous work linking impulsivity and substance use behaviors by examining the relation of `emotional urgency' on cannabis craving and consumption.


Risk Factors For Injection Versus Non-Injection Drug Use Among Men In Kermanshah City, Iran In 2005 : An Observational Study, Kamiar Alaei Jan 2013

Risk Factors For Injection Versus Non-Injection Drug Use Among Men In Kermanshah City, Iran In 2005 : An Observational Study, Kamiar Alaei

Legacy Theses & Dissertations (2009 - 2024)

ABSTRACT


Student-Athletes And Drug Abuse Policies: A Study Of Drug Abuse Policies Of Athletics Departments In A Major Intercollegiate Athletics Conference, Jennifer Hale Jan 2013

Student-Athletes And Drug Abuse Policies: A Study Of Drug Abuse Policies Of Athletics Departments In A Major Intercollegiate Athletics Conference, Jennifer Hale

MPA/MPP/MPFM Capstone Projects

No executive summary.


High-Activity Mutants Of Human Butyrylcholinesterase For Cocaine Abuse Treatment, Liu Xue Jan 2013

High-Activity Mutants Of Human Butyrylcholinesterase For Cocaine Abuse Treatment, Liu Xue

Theses and Dissertations--Pharmacy

Cocaine is a widely abused drug without an FDA-approved medication. It has been recognized as an ideal anti-cocaine medication to accelerate cocaine metabolism producing biologically inactive metabolites via a route similar to the primary cocaine-metabolizing pathway, i.e. butyrylcholinesterase (BChE)-catalyzed hydrolysis. However, the native BChE has a low catalytic activity against cocaine. We recently designed and discovered a set of BChE mutants with a high catalytic activity specifically for cocaine. An ideal, therapeutically valuable mutant of human BChE should have not only a significantly improved catalytic activity against cocaine, but also certain selectivity for cocaine over neurotransmitter acetylcholine (ACh) such …


An Analysis Of Treatment Retention And Attrition In An Australian Therapeutic Community For Substance Abuse Treatment, Mark Robert Porter Jan 2013

An Analysis Of Treatment Retention And Attrition In An Australian Therapeutic Community For Substance Abuse Treatment, Mark Robert Porter

Theses: Doctorates and Masters

Research undertaken in the last three decades has consistently reported that the length of time spent in inpatient and outpatient alcohol and other drug (AOD) treatment programs predicts treatment success (De Leon, Melnick, Kressel, & Jainchill, 1994; Hubbard, Craddock, & Anderson, 2003; Simpson, Joe, Fletcher, Hubbard, & Anglin, 1999). However, treatment attrition rates are high and present a major problem for improving treatment outcomes. Various factors that have been reportedly associated with increased AOD treatment attrition rates include being female, younger clients, clients using methamphetamines, and clients with elevated psychopathology scores. The aim of this thesis is to improve understanding …