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Articles 301 - 317 of 317
Full-Text Articles in Medicine and Health Sciences
Vection Can Be Induced Without Global-Motion Awareness, Takeharu Seno, Stephen A. Palmisano, Hiroyuki Ito, Shoji Sunaga
Vection Can Be Induced Without Global-Motion Awareness, Takeharu Seno, Stephen A. Palmisano, Hiroyuki Ito, Shoji Sunaga
Faculty of Health and Behavioural Sciences - Papers (Archive)
A new vection illusion is reported. Vection was induced even though there was no consciously perceived global display motion corresponding to the self-motion. The resulting experience can be summarised as: ``I feel that I am moving but I do not know why''.
A Maze Of Metaphors Around Glass Ceilings, Paul Smith, Peter Caputi, Nadia Crittenden
A Maze Of Metaphors Around Glass Ceilings, Paul Smith, Peter Caputi, Nadia Crittenden
Faculty of Health and Behavioural Sciences - Papers (Archive)
Purpose – The purpose of this paper is to review many of the diverse metaphors and labels that are used to highlight insights into glass ceilings – the obstacles hindering women reaching the top levels of organizations.
Design/methodology/approach – The development of metaphors and labels related to theories about the causes and consequences of glass ceilings are discussed. They are classified according to whether or not they infer women play a role in creating glass ceilings.
Findings – It is concluded that most metaphor-linked explanations focus on discrimination and prejudice towards women seeking leadership positions. A small number of metaphors …
Seven Out Of Ten Most Popular Vegetables Remain Top Choice During First 3 Months Of A 12 Month Weight Loss Dietary Intervention Trial, Jane O'Shea, Yasmine Probst, Rebecca Thorne, Sara Grafenauer, Linda Tapsell
Seven Out Of Ten Most Popular Vegetables Remain Top Choice During First 3 Months Of A 12 Month Weight Loss Dietary Intervention Trial, Jane O'Shea, Yasmine Probst, Rebecca Thorne, Sara Grafenauer, Linda Tapsell
Faculty of Health and Behavioural Sciences - Papers (Archive)
Increasing vegetable consumption is part of dietary advice for weight loss, but how this converts to vegetable choices is not known. In this context, our aim was to identify the main vegetable groups reported by the study sample in the Healthy Eating and Lifestyle Trial [ACTRN1260000784011] at baseline (Oct 2010-Feb 2011) and after 3mo (Feb - May 2011). Data from diet histories (DH) were analyzed using the AUSNUT 2007 database in Foodworks (Xyris, version 6.0.2562) to determine the average daily amount (g) of vegetables consumed by the study sample. Baseline DH (n=113 subjects; 85 female) exposed 32 vegetable categories. The …
Functional Connectivity In Brain Networks Underlying Cognitive Control In Chronic Cannabis Users, Ian H. Harding, Nadia Solowij, Ben J. Harrison, Michael Takagi, Valentina Lorenzetti, Dan I. Lubman, Marc L. Seal, Christos Pantelis, Murat Yucel
Functional Connectivity In Brain Networks Underlying Cognitive Control In Chronic Cannabis Users, Ian H. Harding, Nadia Solowij, Ben J. Harrison, Michael Takagi, Valentina Lorenzetti, Dan I. Lubman, Marc L. Seal, Christos Pantelis, Murat Yucel
Faculty of Health and Behavioural Sciences - Papers (Archive)
The long-term effect of regular cannabis use on brain function underlying cognitive control remains equivocal. Cognitive control abilities are thought to have a major role in everyday functioning, and their dysfunction has been implicated in the maintenance of maladaptive drug-taking patterns. In this study, the Multi-Source Interference Task was employed alongside functional magnetic resonance imaging and psychophysiological interaction methods to investigate functional interactions between brain regions underlying cognitive control. Current cannabis users with a history of greater than 10 years of daily or near-daily cannabis smoking (n=21) were compared with age, gender, and IQ-matched non-using controls (n=21). No differences in …
The Challenges And Opportunities For Professional Societies In Higher Education In Australasia: A Pest Analysis, Iain Doherty, Caroline Steel, Dominique Parrish
The Challenges And Opportunities For Professional Societies In Higher Education In Australasia: A Pest Analysis, Iain Doherty, Caroline Steel, Dominique Parrish
Faculty of Health and Behavioural Sciences - Papers (Archive)
Professional societies, established to support academic and professional staff in higher education, need to be vigilant of regional and international trends that affect their core business. In this paper, we provide an analysis of political, economic, social and technological factors that are impacting upon the Australasian higher education environment through considering the case of the Australasian Society for Computers in Learning in Tertiary Education (ascilite). Drawing on two ascilite membership surveys along with the relevant literature we identify significant challenges for professional societies and offer some strategic insights for similar regional societies and their executive teams.
Respiratory Component Of The Orienting Reflex: A Novel Sensitive Index Of Sensory-Induced Arousal In Rats, Eugene Nalivaiko, Evgeny Bondarenko, Andreas Lidstrom, Robert J. Barry
Respiratory Component Of The Orienting Reflex: A Novel Sensitive Index Of Sensory-Induced Arousal In Rats, Eugene Nalivaiko, Evgeny Bondarenko, Andreas Lidstrom, Robert J. Barry
Faculty of Health and Behavioural Sciences - Papers (Archive)
In humans, the integrated response to a novel stimulus (orienting reflex, OR) includes behavioral (head turning etc.) and well-characterized physiological components (changes in heart rate, respiration, skin conductance, and EEG patterns). In rodents, the physiological components of the OR include changes in heart rate and cutaneous vasoconstrictor tone, but respiratory changes have so far not been systematically documented. In the present study conducted in adult male Wistar rats, the OR was elicited by 60-dB acoustic tones while animals were in a whole-body plethysmograph for respiratory recordings. In addition to respiration, in different groups of animals we concurrently recorded either EEG, …
If A Picture Tells A Thousand Words, How Useful Are They As A Teaching Tool? Evaluating A Digital Food Photo Resource Within A First Year Tertiary Nutrition Subject, Joanna Baker, Janaye Fish, Karen L. Walton, Anne Therese Mcmahon, Christine J. Brewer, Fiona Manning, Sara Grafenauer, Meredith A. Kennedy, Yasmine Probst
If A Picture Tells A Thousand Words, How Useful Are They As A Teaching Tool? Evaluating A Digital Food Photo Resource Within A First Year Tertiary Nutrition Subject, Joanna Baker, Janaye Fish, Karen L. Walton, Anne Therese Mcmahon, Christine J. Brewer, Fiona Manning, Sara Grafenauer, Meredith A. Kennedy, Yasmine Probst
Faculty of Health and Behavioural Sciences - Papers (Archive)
Abstract of poster presented at Dietitians Association of Australia 16th International Congress of Dietetics, 5-8 September 2012, Sydney Convention & Exhibition Centre, Sydney, Australia.
Growing Use Of Social Media: How Can Dietitians Embrace This Trend?, Qingcai Peng, Yasmine Probst
Growing Use Of Social Media: How Can Dietitians Embrace This Trend?, Qingcai Peng, Yasmine Probst
Faculty of Health and Behavioural Sciences - Papers (Archive)
No abstract provided.
My Time; Your Time; The Time Of Living With Myeloma, Moira Stephens, Christopher F. Jordens, Ian Kerridge, Stacy J. Carter, Heather Mckenzie, Tracy King
My Time; Your Time; The Time Of Living With Myeloma, Moira Stephens, Christopher F. Jordens, Ian Kerridge, Stacy J. Carter, Heather Mckenzie, Tracy King
Faculty of Health and Behavioural Sciences - Papers (Archive)
Abstract of a poster presentation presented at the Joint Meeting of the COSA 39th Annual Scientific Meeting and IPOS 14th World Congress of Psycho-Oncology, 13-15 November 2012, Brisbane Convention and Exhibition Centre.
Amyloid Beta Selectively Modulates Neuronal Trkb Alternative Transcript Expression With Implications For Alzheimer's Disease, J Wong, M Higgins, G Halliday, B Garner
Amyloid Beta Selectively Modulates Neuronal Trkb Alternative Transcript Expression With Implications For Alzheimer's Disease, J Wong, M Higgins, G Halliday, B Garner
Illawarra Health and Medical Research Institute
Dysregulation in brain-derived neurotrophic factor (BDNF)/full-length TrkB (TrkB-TK+) signaling is implicated in promoting neurodegeneration in Alzheimer's disease (AD). BDNF/TrkB-TK+ signaling can be modulated by the presence of truncated TrkB isoforms (TrkB-TK-, TrkB-Shc). All TrkB isoforms are encoded by different alternative transcripts. In this study, we assessed if expression of the three main TrkB alternative transcripts, TrkB-TK+, TrkB-TK-, and TrkB-Shc are altered in AD. Using a cohort of control and AD brains (n=29), we surveyed the hippocampus, temporal cortex, occipital cortex, and cerebellum and found specific increases in TrkB-Shc, a neuron-specific transcript, in the AD hippocampus. No significant changes were detected …
Recent Peritonitis Associates With Mortality Among Patients Treated With Peritoneal Dialysis, Neil Boudville, Anna Kemp, Philip Clayton, Wai Lim, Sunil V. Badve, Carmel M. Hawley, Stephen P. Mcdonald, Kathryn J. Wiggins, Kym M. Bannister, Fiona G. Brown, David W. Johnson
Recent Peritonitis Associates With Mortality Among Patients Treated With Peritoneal Dialysis, Neil Boudville, Anna Kemp, Philip Clayton, Wai Lim, Sunil V. Badve, Carmel M. Hawley, Stephen P. Mcdonald, Kathryn J. Wiggins, Kym M. Bannister, Fiona G. Brown, David W. Johnson
Illawarra Health and Medical Research Institute
Peritonitis is a major complication of peritoneal dialysis, but the relationship between peritonitis and mortality among these patients is not well understood. In this case-crossover study, we included the 1316 patients who received peritoneal dialysis in Australia and New Zealand from May 2004 through December 2009 and either died on peritoneal dialysis or within 30 days of transfer to hemodialysis. Each patient served as his or her own control. The mean age was 70 years, and the mean time receiving peritoneal dialysis was 3 years. In total, there were 1446 reported episodes of peritonitis with 27% of patients having ≥2 …
Srp20 Regulates Trkb Pre-Mrna Splicing To Generate Trkb-Shc Transcripts With Implications For Alzheimer's Disease, Jenny Wong, Brett Garner, Glenda M. Halliday, John B.J Kwok
Srp20 Regulates Trkb Pre-Mrna Splicing To Generate Trkb-Shc Transcripts With Implications For Alzheimer's Disease, Jenny Wong, Brett Garner, Glenda M. Halliday, John B.J Kwok
Illawarra Health and Medical Research Institute
Previously, we reported elevated levels of the neuronspecific tropomyosin receptor kinase B (TrkB) transcript, TrkB- sarc homology containing (Shc) in the hippocampus of Alzheimer’s disease (AD) brains. In this study, we determined how TrkB-Shc transcripts are increased in AD. Utilizing a TrkB minigene transiently transfected into SHSY5Y cells, we found increased exon 19 inclusion in TrkB minigene transcripts (to generate TrkB-Shc) following cellular exposure to amyloid beta 1–42 (Ab42). As this suggested altered TrkB pre-mRNA splicing in AD, we conducted an in silico screening for putative splice regulatory protein-binding sites in the intron/exon splice regulatory regions of exons 18 and …
Functional Expression Of The Damage-Associated Molecular Pattern Receptor P2x7 On Canine Kidney Epithelial Cells, Iman Jalilian, Mari Spildrejorde, Aine Seavers, Belinda L. Curtis, Jason D. Mcarthur, Ronald Sluyter
Functional Expression Of The Damage-Associated Molecular Pattern Receptor P2x7 On Canine Kidney Epithelial Cells, Iman Jalilian, Mari Spildrejorde, Aine Seavers, Belinda L. Curtis, Jason D. Mcarthur, Ronald Sluyter
Illawarra Health and Medical Research Institute
Epithelial cells are important in inflammation and immunity. In this study, we examined if Madin-Darby canine kidney (MDCK) epithelial cells express functional P2X7 receptors, which bind the damage-associated molecular pattern extracellular adenosine 5'-triphosphate (ATP). Reverse transcription (RT)-PCR and immunoblotting revealed the expression of P2X7 in MDCK cells. A flow cytometric assay demonstrated that ATP or 2'(3')-O-(4-benzoylbenzoyl)ATP induced ethidium(+) uptake into MDCK cells, and that this process was impaired by the P2X7 antagonists KN-62 and A438079. RT-PCR also demonstrated the presence of Toll-like receptor 4, NALP3, caspase-1, interleukin-1β and interleukin-18 in MDCK cells, as well as in positive control LPS-primed canine …
Cognitive Phenotyping Of Amyloid Precursor Protein Transgenic J20 Mice, Tim Karl, Surabhi Bhatia, David Cheng, Woojin Scott Kim, Brett Garner
Cognitive Phenotyping Of Amyloid Precursor Protein Transgenic J20 Mice, Tim Karl, Surabhi Bhatia, David Cheng, Woojin Scott Kim, Brett Garner
Illawarra Health and Medical Research Institute
Transgenic mice that express familial Alzheimer's disease mutant forms of the human amyloid precursor protein (hAPP) have proved to be invaluable in determining the impact that the neurotoxic amyloid-β peptide has in vivo. In addition to the propensity to accumulate cerebral amyloid plaques, a crucial characteristic of hAPP mouse models is their cognitive impairments. To date the most widely used test for analyzing cognitive impairment in hAPP mice is the Morris water maze (MWM) which, due to the fact that mice are not "natural" swimmers, may not always be the ideal paradigm to investigate cognitive behaviours. Furthermore, not all cognitive …
Guidelines For The Management Of Absolute Cardiovascular Disease Risk, Leonard F. Arnolda
Guidelines For The Management Of Absolute Cardiovascular Disease Risk, Leonard F. Arnolda
Illawarra Health and Medical Research Institute
The National Vascular Disease Prevention Alliance (NVDPA) is an alliance of four leading and well-known Australian charities: Diabetes Australia, the National Heart Foundation of Australia, Kidney Health Australia and the National Stroke Foundation. In 2000, these four charities began to work together to reduce the burden of cardiovascular disease in Australia. Much of the work of the NVDPA to date has been to promote the use of an 'absolute risk' approach to predicting risk of cardiovascular disease. The NVDPA advocates to government and professional bodies for a health system that supports an absolute risk approach. The NVDPA aims to raise …
Neurons Derived From Human Embryonic Stem Cells Extend Long-Distance Axonal Projections Through Growth Along Host White Matter Tracts After Intra-Cerebral Transplantation, Mark Denham, Clare L. Parish, Bryan Leaw, Jordan Wright, Christopher Reid, Steven Petrou, Mirella Dottori, Lachlan H. Thompson
Neurons Derived From Human Embryonic Stem Cells Extend Long-Distance Axonal Projections Through Growth Along Host White Matter Tracts After Intra-Cerebral Transplantation, Mark Denham, Clare L. Parish, Bryan Leaw, Jordan Wright, Christopher Reid, Steven Petrou, Mirella Dottori, Lachlan H. Thompson
Illawarra Health and Medical Research Institute
Human pluripotent stem cells have the capacity for directed differentiation into a wide variety of neuronal subtypes that may be useful for brain repair. While a substantial body of research has lead to a detailed understanding of the ability of neurons in fe tal tissue grafts to structurally and functionally integrate after intra-cerebral transplantation, we are only just beginning to understand the in vivo properties of neurons derived from human pluripotent stem cells. Here we have utilised the human embryonic stem (ES) cell line Envy, which constitutively expresses green fluorescent protein (GFP), in order to study the in vivo properties …
Non-Viral Generation Of Neural Precursor-Like Cells From Adult Human Fibroblasts, C Maucksch, E Firmin, C Butler-Munro, J Montgomery, Mirella Dottori, Bronwen Connor
Non-Viral Generation Of Neural Precursor-Like Cells From Adult Human Fibroblasts, C Maucksch, E Firmin, C Butler-Munro, J Montgomery, Mirella Dottori, Bronwen Connor
Illawarra Health and Medical Research Institute
Recent studies have reported direct reprogramming of human fibroblasts to mature neurons by the introduction of defined neural genes. This technology has potential use in the areas of neurological disease modeling and drug development. However, use of induced neurons for large-scale drug screening and cell-based replacement strategies is limited due to their inability to expand once reprogrammed. We propose it would be more desirable to induce expandable neural precursor cells directly from human fibroblasts. To date several pluripotent and neural transcription factors have been shown to be capable of converting mouse fibroblasts to neural stem/precursor-like cells when delivered by viral …