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Histiocytosis X: Review Literature And A Case Report(โรคฮิสติโอไซโตซิส เอ็กซ์ : รายงานผู้ป่วยและบทความปริทัศน์), Kittipong Dhanuthai, Wichit Tharanon

Chulalongkorn University Dental Journal

Histiocytosis X encompasses three clinical entities: eosinophilic granuloma, Hand-Schüller-Christian disease, and Letterer-Siwe disease. It usually occurs in young-aged group and is characterized by the proliferation of Langerhans cells and a collection of eosinophils Radiographically, it appears as single or multiple areas of well-defined radiolucencies or the appearance of teeth floating in the air in severe cases. Because of its varied oral manifestations which can result in potential diagnostic problem, the importance of biopsy, especially the demonstration of Langerhans cells, is stressed. Surgery is the preferred treatment for most of the jaws lesions while radiotherapy and chemotherapy should be reserved for …