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Articles 1 - 30 of 67
Full-Text Articles in Medicine and Health Sciences
Identifying Rural Health Clinics Within The Transformed Medicaid Statistical Information System (T-Msis) Analytic Files, Katherine Ahrens Mph, Phd, Zachariah Croll, Yvonne Jonk Phd, John Gale Ms, Heidi O'Connor Ms
Identifying Rural Health Clinics Within The Transformed Medicaid Statistical Information System (T-Msis) Analytic Files, Katherine Ahrens Mph, Phd, Zachariah Croll, Yvonne Jonk Phd, John Gale Ms, Heidi O'Connor Ms
Rural Health Clinics
Researchers at the Maine Rural Health Research Center describe a methodology for identifying Rural Health Clinic encounters within the Medicaid claims data using Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files.
Background: There is limited information on the extent to which Rural Health Clinics (RHC) provide pediatric and pregnancy-related services to individuals enrolled in state Medicaid/CHIP programs. In part this is because methods to identify RHC encounters within Medicaid claims data are outdated.
Methods: We used a 100% sample of the 2018 Medicaid Demographic and Eligibility and Other Services Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files for 20 states …
Explaining Adult Obesity, Severe Obesity, And Bmi: Five Decades Of Change, Ashley W. Kranjac, Dinko Kranjac
Explaining Adult Obesity, Severe Obesity, And Bmi: Five Decades Of Change, Ashley W. Kranjac, Dinko Kranjac
Sociology Faculty Articles and Research
Obesity rates have increased across all segments of society since the late 1970s, but the reason behind population-level increases in body weight remains unclear. We used the 1971–2020 NHANES data to examine whether the observed trend in obesity prevalence is attributable to changing public health behaviors (i.e., intracohort change) or changing publics (i.e., cohort replacement). We partitioned total change in mean BMI, and rates of obesity and severe obesity, into its IC and CR components using linear and algebraic decomposition methods. We found that the IC mechanism (i.e., broad sectors of individuals changing) plays a dominant role in the overall …
The Association Between College Age Students' Nutrition Intake And Depression, Mackenzie Allen
The Association Between College Age Students' Nutrition Intake And Depression, Mackenzie Allen
Honors Projects
The research performed was to determine a correlation between depression and nutrient intake in college age students. This study used NHANES publicily available data and IBM's SPSS statistical software to analyze a correlation between depression and nutrition/lifestyle variables: vitamin D, vitamin B12, saturated fatty acids, unsaturated fatty acids, fiber, and exercise. The study found that fiber and unsaturated fatty acid intake had a negative correlation with depression, meaning that as the intake of these nutrients increased, depression decreased. This research reveals key factors to improve the nutritional status of college age students, along with their emotional wellbeing.
Deconstructing Sex Differences In C-Reactive Protein Trends Over Time, Ashley W. Kranjac, Dinko Kranjac, Olivia Lounsbury
Deconstructing Sex Differences In C-Reactive Protein Trends Over Time, Ashley W. Kranjac, Dinko Kranjac, Olivia Lounsbury
Sociology Faculty Articles and Research
Objectives
Heightened inflammatory state, as measured by circulating C-reactive protein (CRP) levels, can promote inflammation-mediated disease risk. It is important to account for population fluctuation and sex variation in serum CRP concentrations on overall time trends.
Methods
Using the National Health and Nutrition Examination Survey data, we specify linear and algebraic decomposition models separately by sex to identify the drivers of the changing trends in the distribution of CRP values in the population.
Results
We found a nonsignificant overall increase in CRP, but a significant decrease among women and increase among men, over a 10-year period. We then used linear …
Postoperative Opioid-Prescribing Practices In Nasal Surgery: A Prospective Study, Brian M. Yan, S. Hamad Sagheer, Cory D. Bovenzi, Uche Nwagu, David Cognetti, Howard Krein, Ryan Heffelfinger
Postoperative Opioid-Prescribing Practices In Nasal Surgery: A Prospective Study, Brian M. Yan, S. Hamad Sagheer, Cory D. Bovenzi, Uche Nwagu, David Cognetti, Howard Krein, Ryan Heffelfinger
Phase 1
Introduction: Within facial plastic and reconstructive surgery (FPRS), prescription practices have trended toward prescribing larger amounts of perioperative opioids. However, there is limited literature regarding the postoperative pain experience and opioid consumption for FPRS. The purpose of our study was to investigate opioid prescription and consumption following procedures of the nose, with the aim of developing evidence-based guidelines for postoperative pain management.
Methods: In this prospective single center study, morphine milligram equivalents (MME) consumption and pain scores were collected in 72 patients who underwent nasal surgery. Patient demographics, MME use, and pain scores were examined. MME use was compared …
Electromyographical Assessments Of Recommended Neck And Trunk Positions For Dental Hygienists, Margaret F. Lemaster, Kyle J. Kelleran, Maryam Moeini, Daniel M. Russell
Electromyographical Assessments Of Recommended Neck And Trunk Positions For Dental Hygienists, Margaret F. Lemaster, Kyle J. Kelleran, Maryam Moeini, Daniel M. Russell
Rehabilitation Sciences Faculty Publications
Purpose: Dental professionals are recommended to limit neck and trunk flexion to within 20° of a neutral (0°) body posture, however empirical support for the recommendations is lacking. The purpose of this study was to determine whether there are differences in muscle workload between a range of neck and trunk postures in a population of dental hygiene students.
Methods: Fifteen first semester senior dental hygiene students with no history of neck and trunk injury volunteered to participate. Surface electromyography was used to record muscle activity from two neck extensors muscles, cervical erector spinae (CES) and upper trapezius (UT), and two …
Employability In Academe For Athletic Trainers With The Doctor Of Athletic Training Degree, Bonnie L. Van Lunen, Stephanie H. Clines, Tyler Reems, Lindsey E. Eberman, Dorice A. Hankemeier, Cailee E. Welch
Employability In Academe For Athletic Trainers With The Doctor Of Athletic Training Degree, Bonnie L. Van Lunen, Stephanie H. Clines, Tyler Reems, Lindsey E. Eberman, Dorice A. Hankemeier, Cailee E. Welch
Rehabilitation Sciences Faculty Publications
The doctor of athletic training (DAT) degree has recently been introduced into academe. Limited literature exists regarding how individuals with this degree can become part of an athletic training faculty. To identify department chairs' perceptions of the DAT degree and determine whether they viewed the degree as viable when hiring new faculty within a postbaccalaureate professional athletic training program. Cross-sectional study. Online survey instrument. A total of 376 department chairs who had oversight of Commission on Accreditation of Athletic Training Education athletic training programs were invited to participate. Of these, 190 individuals (50.5%) accessed the survey, and 151 of the …
Attitudes Of Virginia Dentists Toward Dental Therapists: A Pilot Study, Adaira L. Howell, Susan Lynn Tolle, Emily A. Ludwig, Denise M. Claiborne
Attitudes Of Virginia Dentists Toward Dental Therapists: A Pilot Study, Adaira L. Howell, Susan Lynn Tolle, Emily A. Ludwig, Denise M. Claiborne
Dental Hygiene Faculty Publications
Purpose: The purpose of this pilot study was to determine perceptions of Virginia (VA) dentists toward mid-level dental providers, specifically dental therapists (DT), and determine whether membership in the American Dental Association (ADA) membership affected attitudes.
Methods: A convenience sample of 1208 dentists in the state of VA were invited to participate in an electronic survey. The instrument consisted of 11 Likert type scale questions assessing attitudes toward DTs. Additional items included the appropriate level of education and supervision of a DT, and five demographic questions. Descriptive statistics were used to analyze the data. A one-sample t-test was used to …
Decomposing Differences In Coronavirus Disease 2019-Related Case-Fatality Rates Across Seventeen Nations, Ashley Wendell Kranjac, Dinko Kranjac
Decomposing Differences In Coronavirus Disease 2019-Related Case-Fatality Rates Across Seventeen Nations, Ashley Wendell Kranjac, Dinko Kranjac
Sociology Faculty Articles and Research
As of 1 November 2020, estimated case-fatality rates associated with coronavirus disease 2019 are not uniformly patterned across the world and differ substantially in magnitude. Given the global spatial heterogeneity in case-fatality rates, we applied the Blinder-Oaxaca regression decomposition technique to identify how putative sociodemographic, structural, and environmental sources influence variation in case-fatality rates. We show that compositional and associational differences in country-level risk factors explain a substantial proportion of the coronavirus disease 2019-related case-fatality rate gap across nations. Asian countries fair better vis-à-vis case-fatality rate differences mainly due to variation in returns to sociodemographic, structural, and environmental sources among …
The Effects Of Zoledronate And Sleep Deprivation On The Distal Femur Trabecular Thickness Of Ovariectomized Rats: Application Of Different Statistical Methods, Erin Nolte
Student Scholar Symposium Abstracts and Posters
Osteoporosis is a disease that causes the degradation of bone, leading to an increased risk of fracture. 1 in 3 women over the age of 50 will be affected by Osteoporosis. This study aims to understand how bone is affected by sleep deprivation in estrogen-deficient rats, and how Zoledronate might negate the inimical effects of sleep deprivation on bone. As bone mineral density (BMD) is a crude evaluation of the architectural changes seen in Osteoporosis, trabecular thickness may serve as a better single evaluation of bone health. 31 Wistar female rats were ovariectomized and separated into 4 random groups. The …
Investigating Major League Baseball Pitchers And Quality Of Contact Through Cluster Analysis, Charlie Marcou
Investigating Major League Baseball Pitchers And Quality Of Contact Through Cluster Analysis, Charlie Marcou
Honors Projects
This paper investigates the quality of contact that a pitcher allows. Not much is currently known about quality of contact, but if factors determining quality of contact could be determined it could assist teams in identifying and developing pitching talent. There are many problems that come with investigating the control pitchers have over contact allowed, but one area to investigate is whether quality of contact is a repeatable skill. Furthermore, if it is a repeatable skill, then it is important to investigate what kind of benefit controlling contact allowed brings a pitcher. Along with this, groundball and flyball tendencies, and …
10th Annual Postdoctoral Science Symposium, University Of Texas Md Anderson Cancer Center Postdoctoral Association
10th Annual Postdoctoral Science Symposium, University Of Texas Md Anderson Cancer Center Postdoctoral Association
Annual Postdoctoral Science Symposium Abstracts
The Annual Postdoctoral Science Symposium (APSS) was initiated on August 4, 2011, by the MD Anderson Postdoctoral Association to provide a platform for talented postdoctoral fellows throughout the Texas Medical Center to present their work to a wider audience.
APSS is a scientific symposium organized by postdoctoral fellows from The University of Texas MD Anderson Cancer Center that welcomes submissions and presentations from postdoctoral fellows from all Texas Medical Center affiliated institutions and other Houston area institutions. The APSS provides a professional venue for postdoctoral scientists to develop, clarify and refine their research as result of formal reviews and critiques …
Systemic Th17 Response In The Presence Of Periodontal Inflammation, Lina J Suárez, Daniel E Vargas, Adriana Rodríguez, Roger M Arce, Nelly S Roa
Systemic Th17 Response In The Presence Of Periodontal Inflammation, Lina J Suárez, Daniel E Vargas, Adriana Rodríguez, Roger M Arce, Nelly S Roa
Journal Articles
BACKGROUND: The relationship between periodontitis and the pathogenesis of other inflammatory diseases, such as diabetes, rheumatoid arthritis and obesity has been an important topic of study in recent decades. The Th17 pathway plays a significant role in how local inflammation can influence systemic inflammation in the absence of systemic pathology.
OBJECTIVE: To determine Th17 biased-cells in systemically healthy patients in the presence of generalized chronic periodontitis.
METHODOLOGY: A total of 28 patients were recruited without systemic inflammatory pathology, which was determined by clinical history, the Health Assessment Questionnaire (HAQ) and rheumatoid factor detection. Of these patients, 13 were diagnosed as …
External Barriers For Including Parents Of Preterm Infants In A Randomised Clinical Trial In The Neonatal Intensive Care Unit In Sweden: A Descriptive Study, Evalotte Mörelius, Emma Olsson, Charlotte Sahlén Helmer, Ylva Thernström Blomqvist, Charlotte Angelhoff
External Barriers For Including Parents Of Preterm Infants In A Randomised Clinical Trial In The Neonatal Intensive Care Unit In Sweden: A Descriptive Study, Evalotte Mörelius, Emma Olsson, Charlotte Sahlén Helmer, Ylva Thernström Blomqvist, Charlotte Angelhoff
Research outputs 2014 to 2021
© Author(s) (or their employer(s)) 2020. Objectives Performing randomised controlled trials (RCTs) in neonatal intensive care is challenging in many ways. While restrictive inclusion criteria or busy study protocols are obvious barriers, external barriers leading to termination of a study are seldom discussed. The aim of this study was to describe barriers for inclusion of families in neonatal intensive care in an RCT aiming to evaluate the effects of continuous skin-to-skin contact on mood and sleep quality in parents of preterm infants, as well as the quality of parent-infant interaction and salivary cortisol concentrations at the time of discharge. Design …
9th Annual Postdoctoral Science Symposium, University Of Texas Md Anderson Cancer Center Postdoctoral Association
9th Annual Postdoctoral Science Symposium, University Of Texas Md Anderson Cancer Center Postdoctoral Association
Annual Postdoctoral Science Symposium Abstracts
The mission of the Annual Postdoctoral Science Symposium (APSS) is to provide a platform for talented postdoctoral fellows throughout the Texas Medical Center to present their work to a wider audience. The MD Anderson Postdoctoral Association convened its inaugural Annual Postdoctoral Science Symposium (APSS) on August 4, 2011.
The APSS provides a professional venue for postdoctoral scientists to develop, clarify, and refine their research as a result of formal reviews and critiques of faculty and other postdoctoral scientists. Additionally, attendees discuss current research on a broad range of subjects while promoting academic interactions and enrichment and developing new collaborations.
Predictive Diagnostic Analysis Of Mammographic Breast Tissue Microenvironment, Dexter G. Canning
Predictive Diagnostic Analysis Of Mammographic Breast Tissue Microenvironment, Dexter G. Canning
Honors College
Improving computer-aided early detection techniques for breast cancer is paramount because current technology has high false positive rates. Existing methods have led to a substantial number of false diagnostics, which lead to stress, unnecessary biopsies, and an added financial burden to the health care system. In order to augment early detection methodology, one must understand the breast microenvironment. The CompuMAINE Lab has researched computational metrics on mammograms based on an image analysis technique called the Wavelet Transform Modulus Maxima (WTMM) method to identify the fractal and roughness signature from mammograms. The WTMM method was used to color code the mammograms …
Assessment Of Physical Fitness After Bariatric Surgery And Its Association With Protein Intake And Type Of Cholecalciferol Supplementation, Hendrika J M Smelt, Sjaak Pouwels, Alper Celik, Adarsh Gupta, Johannes F Smulders
Assessment Of Physical Fitness After Bariatric Surgery And Its Association With Protein Intake And Type Of Cholecalciferol Supplementation, Hendrika J M Smelt, Sjaak Pouwels, Alper Celik, Adarsh Gupta, Johannes F Smulders
Rowan-Virtua School of Osteopathic Medicine Faculty Scholarship
Background: Several studies showed that there is a relationship between vitamin and mineral status and muscle strength. In particular this is the case for handgrip strength (HS) and vitamin D deficiency. In bariatric surgery there is a risk of decrease in muscle strength after surgery and also vitamin and mineral deficiencies are not uncommon. The aim of this study is to assess the effect of low vitamin 25 (OH) cholecalciferol levels, high dose cholecalciferol supplementation regime and protein intake on physical fitness, measured using handgrip strength (HS) and the shuttle walk run test (SWRT). Methods: For this retrospective …
Do Patient Reported Outcome Measurement Information System (Promis) Scales Demonstrate Responsiveness As Well As Disease-Specific Scales In Patients Undergoing Knee Arthroscopy?, Raymond J. Kenney, Jeff Houck, Brian D. Giordano, Judith F. Baumhauer, Meghan Herbert, Michael D. Maloney
Do Patient Reported Outcome Measurement Information System (Promis) Scales Demonstrate Responsiveness As Well As Disease-Specific Scales In Patients Undergoing Knee Arthroscopy?, Raymond J. Kenney, Jeff Houck, Brian D. Giordano, Judith F. Baumhauer, Meghan Herbert, Michael D. Maloney
Faculty Publications - College of Physical Therapy
Background: The Patient Reported Outcomes Information System (PROMIS) is an efficient metric able to detect changes in global health. Purpose: To assess the responsiveness, convergent validity, and clinically important difference (CID) of PROMIS compared with disease-specific scales after knee arthroscopy. Study Design: Cohort study (Diagnosis); Level of evidence, 2.
Methods: A prospective institutional review board–approved study collected PROMIS Physical Function (PF), PROMIS Pain Interference (PI), International Knee Documentation Committee (IKDC), and Knee injury and Osteoarthritis Outcome Score (KOOS) results in patients undergoing knee arthroscopy. The change from preoperative to longest follow-up was used in analyses performed to determine responsiveness, convergent …
Artificial Intelligence: Practical Primer For Clinical Research In Cardiovascular Disease, Nobuyuki Kagiyama, Sirish Shrestha, Peter D. Farjo, Partho P. Sengupta
Artificial Intelligence: Practical Primer For Clinical Research In Cardiovascular Disease, Nobuyuki Kagiyama, Sirish Shrestha, Peter D. Farjo, Partho P. Sengupta
Faculty & Staff Scholarship
No abstract provided.
Response Shift After A 4-Week Multimodal Intervention For Chronic Ankle Instability, Cameron J. Powden, Matthew C. Hoch, Beth E. Jamali, Johanna M. Hoch
Response Shift After A 4-Week Multimodal Intervention For Chronic Ankle Instability, Cameron J. Powden, Matthew C. Hoch, Beth E. Jamali, Johanna M. Hoch
Rehabilitation Sciences Faculty Publications
Context The accurate evaluation of self-reported changes in function throughout the rehabilitation process is important for determining patient progression. Currently, how a response shift (RS) may affect the accuracy of self-reported functional assessment in a population with chronic ankle instability (CAI) is unknown.
Objective To examine the RS in individuals with CAI after a 4-week multimodal rehabilitation program.
Design Controlled laboratory study.
Setting Laboratory.
Patients or Other Participants Twenty adults (5 men, 15 women; age = 24.35 ± 6.95 years, height = 169.29 ± 10.10 cm, mass = 70.58 ± 12.90 kg) with self-reported CAI participated. Inclusion criteria were at …
School‐Level Body Mass Index Shapes Children's Weight Trajectories, Ashley W. Kranjac
School‐Level Body Mass Index Shapes Children's Weight Trajectories, Ashley W. Kranjac
Sociology Faculty Articles and Research
BACKGROUND
Embedded within children's weight trajectories are complex environmental contexts that influence obesity risk. As such, the normative environment of body mass index (BMI) within schools may influence children's weight trajectories as they age from kindergarten to fifth grade.
METHODS
I use 5 waves of the ECLS‐K—Kindergarten Class 1998‐1999 data and a series of multilevel growth models to examine whether attending schools with higher overall BMI influences children's weight status over time.
RESULTS
Results show that, net of child, family, and school sociodemographic characteristics, children who attend schools with higher rates of obesity have increased weight compared to children who …
Parametric And Nonparametric Tests In Spine Research: Why Do They Matter?, Sarah Hopkins, Joseph R Dettori, Jens R Chapman
Parametric And Nonparametric Tests In Spine Research: Why Do They Matter?, Sarah Hopkins, Joseph R Dettori, Jens R Chapman
Articles, Abstracts, and Reports
No abstract provided.
Common Pitfalls In Analysis Of Tissue Scores, David K. Meyerholz, Nathan L. Tintle, Amanda P. Beck
Common Pitfalls In Analysis Of Tissue Scores, David K. Meyerholz, Nathan L. Tintle, Amanda P. Beck
Faculty Work Comprehensive List
Histopathology remains an important source of descriptive biological data in biomedical research. Recent petitions for enhanced reproducibility in scientific studies have elevated the role of tissue scoring (semiquantitative and quantitative) in research studies. Effective tissue scoring requires appropriate statistical analysis to help validate the group comparisons and give the pathologist confidence in interpreting the data. Each statistical test is typically founded on underlying assumptions regarding the data. If the underlying assumptions of a statistical test do not match the data, then these tests can lead to increased risk of erroneous interpretations of the data. The choice of appropriate statistical test …
Fast And Powerful Genome Wide Association Of Dense Genetic Data With High Dimensional Imaging Phenotypes, Habib Ganjgahi, Anderson M. Winkler, David C. Glahn, John Blangero, Brian Donohue, Peter Kochunov, Thomas E. Nichols
Fast And Powerful Genome Wide Association Of Dense Genetic Data With High Dimensional Imaging Phenotypes, Habib Ganjgahi, Anderson M. Winkler, David C. Glahn, John Blangero, Brian Donohue, Peter Kochunov, Thomas E. Nichols
School of Medicine Publications and Presentations
Genome wide association (GWA) analysis of brain imaging phenotypes can advance our understanding of the genetic basis of normal and disorder-related variation in the brain. GWA approaches typically use linear mixed effect models to account for non-independence amongst subjects due to factors, such as family relatedness and population structure. The use of these models with high-dimensional imaging phenotypes presents enormous challenges in terms of computational intensity and the need to account multiple testing in both the imaging and genetic domain. Here we present a method that makes mixed models practical with high-dimensional traits by a combination of a transformation applied …
Indicators For Early Assessment Of Palliative Care In Lung Cancer Patients: A Population Study Using Linked Health Data, Maria Kelly, Katie M. O'Brien, Michael Lucey, Kerri Clough-Gorr, Ailish Hannigan
Indicators For Early Assessment Of Palliative Care In Lung Cancer Patients: A Population Study Using Linked Health Data, Maria Kelly, Katie M. O'Brien, Michael Lucey, Kerri Clough-Gorr, Ailish Hannigan
Department of Mathematics Publications
Analysing linked, routinely collected data may be useful to identify characteristics of patients with suspected lung cancer who could benefit from early assessment for palliative care. The aim of this study was to compare characteristics of newly diagnosed lung cancer patients dying within 30 days of diagnosis (short term survivors) with those surviving more than 30 days. To identify indicators for early palliative care assessment we distinguished between characteristics available at diagnosis (age, gender, smoking status, marital status, comorbid disease, admission type, tumour stage and histology) from those available post diagnosis. A second aim was to examine the association between …
Statistical Forecasting Models Used To Predict Daily Patient Volumes In The Emergency Department: A Proposal For A Systematic Review, Jon White
Interprofessional Research and Innovations Council
Statistical Forecasting Models Used to Predict Daily Patient Volumes in the Emergency Department: A Proposal for a Systematic Review
Jon White, MS, BSN, RN, CCRN
Background: The existing and projected worldwide shortage of nurses requires numerous distinct solutions to prevent a healthcare crisis. Proposed solutions typically address the situation from different angles, including identifying ways to add new nurses to the workforce, or finding new ways to work with limited resources. This review examines the efficacy of forecasting demand in one area of the hospital, understanding the potential of its uses for short-term resource balancing and projection of need.
This …
The Effect Of Tackling Training On Head Accelerations In Youth American Football, Eric Schussler, Richard J. Jagacinski, Susan E. White, Ajit M. Chaudhari, John A. Buford, James A. Onate
The Effect Of Tackling Training On Head Accelerations In Youth American Football, Eric Schussler, Richard J. Jagacinski, Susan E. White, Ajit M. Chaudhari, John A. Buford, James A. Onate
Rehabilitation Sciences Faculty Publications
Background: Many organizations have introduced frameworks to reduce the incidence of football related concussions through proper equipment fitting, coach education, and alteration of tackling technique.
Purpose: The purpose of this study was to examine the effects of training in a vertical, head up tackling style on the number of head accelerations experienced while tackling in a controlled laboratory situation. The authors hypothesized that training in a head up tackling technique would reduce the severity of head acceleration experienced by participants.
Design: Controlled Laboratory Study.
Methods: Twenty-four participants (11.5 ± 0.6 years old, 60.5 ± 2.2 in, 110 ± 18.4 lbs.) …
Current Research And Statistical Practices In Sport Science And A Need For Change, Jake R. Bernards, Kimitake Sato, G. Gregory Haff, Caleb D. Bazyler
Current Research And Statistical Practices In Sport Science And A Need For Change, Jake R. Bernards, Kimitake Sato, G. Gregory Haff, Caleb D. Bazyler
ETSU Faculty Works
Current research ideologies in sport science allow for the possibility of investigators producing statistically significant results to help fit the outcome into a predetermined theory. Additionally, under the current Neyman-Pearson statistical structure, some argue that null hypothesis significant testing (NHST) under the frequentist approach is flawed, regardless. For example, a p-value is unable to measure the probability that the studied hypothesis is true, unable to measure the size of an effect or the importance of a result, and unable to provide a good measure of evidence regarding a model or hypothesis. Many of these downfalls are key questions researchers strive …
Degree Of Twisting And Duration Of Symptoms Are Prognostic Factors Of Testis Salvage During Episodes Of Testicular Torsion, Adam S. Howe, Vinaya Vasudevan, Michael Kongnyuy, Kevin Rychik, Lisa A. Thomas, Maria Matuskova, Steven C. Friedman, Jordan S. Gitlin, Edward F. Reda, Lane S. Palmer
Degree Of Twisting And Duration Of Symptoms Are Prognostic Factors Of Testis Salvage During Episodes Of Testicular Torsion, Adam S. Howe, Vinaya Vasudevan, Michael Kongnyuy, Kevin Rychik, Lisa A. Thomas, Maria Matuskova, Steven C. Friedman, Jordan S. Gitlin, Edward F. Reda, Lane S. Palmer
Publications and Research
Background: Testicular torsion is surgical emergency. Prompt diagnosis and treatment of testicular torsion is essential for testicular viability. At surgical exploration, the spermatic cord is seen twisted a variable number of times around its longitudinal axis. There is scant data regarding the degree of twisting and its association with testis outcomes. The purpose of our study is to explore how the degree of torsion factors into testicular outcome using follow-up data.
Methods: We retrospectively reviewed the records of adolescent males who presented with testicular torsion to our institution, looking at duration of pain symptoms, degree of torsion documented in the …
Gene-Set Meta-Analysis Of Lung Cancer Identifies Pathway Related To Systemic Lupus Erythematosus, Albert Rosenberger, Melanie Sohns, Stefanie Friedrichs, Rayjean J. Hung, Gord Fehringer, John Mclaughlin, Christopher I. Amos, Paul Brennan, Angela Risch, Irene Bruske, Neil E. Caporaso, Maria Teresa Landi, David C. Christiani, Yongyue Wei, Heike Bickeboller
Gene-Set Meta-Analysis Of Lung Cancer Identifies Pathway Related To Systemic Lupus Erythematosus, Albert Rosenberger, Melanie Sohns, Stefanie Friedrichs, Rayjean J. Hung, Gord Fehringer, John Mclaughlin, Christopher I. Amos, Paul Brennan, Angela Risch, Irene Bruske, Neil E. Caporaso, Maria Teresa Landi, David C. Christiani, Yongyue Wei, Heike Bickeboller
Dartmouth Scholarship
Introduction: Gene-set analysis (GSA) is an approach using the results of single-marker genome-wide association studies when investigating pathways as a whole with respect to the genetic basis of a disease. Methods: We performed a meta-analysis of seven GSAs for lung cancer, applying the method META- GSA. Overall, the information taken from 11,365 cases and 22,505 controls from within the TRICL/ILCCO consortia was used to investigate a total of 234 pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. Results: META-GSA reveals the systemic lupus erythematosus KEGG pathway hsa05322 , driven by the gene region 6p21-22, as also …