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Full-Text Articles in Medicine and Health Sciences

A Field Investigation Of Meiofaunal Dispersal: Tidal Resuspension And Implications, Susan S. Bell, K. M. Sherman Oct 1980

A Field Investigation Of Meiofaunal Dispersal: Tidal Resuspension And Implications, Susan S. Bell, K. M. Sherman

Integrative Biology Faculty and Staff Publications

Presence of meiofauna in resuspended sediments was investigated in a tidal creek system employing a specially designed core sampler and quick freezing techniques. Forty core samples were taken during 4 successive ebb tides to determine the distribution of meiofauna in (a) overlying water; (b) resuspended sediment; and (c) undisturbed sediment fractions of each sample. Our experiments demonstrate that 13-44 % of the meiobenthic copepod subcommunity was present in overlying and resuspended sediment fractions, while only a small percentage of nematodes was found simultaneously in these layers. We suggest that selected meiofauna may disperse through tidally coupled mechanisms and that such …


Rat Dendritic Cells Function As Accessory Cells And Control The Production Of A Soluble Factor Required For Mitogenic Responses Of T Lymphocytes., Wolfgang E. Klinkert, Jon H. Labadie, James P. O'Brien, Carl F. Beyer, William E. Bowers Sep 1980

Rat Dendritic Cells Function As Accessory Cells And Control The Production Of A Soluble Factor Required For Mitogenic Responses Of T Lymphocytes., Wolfgang E. Klinkert, Jon H. Labadie, James P. O'Brien, Carl F. Beyer, William E. Bowers

Dartmouth Scholarship

Transformation of T lymphocytes, induced by treatment with periodate or with neuraminidase plus galactose oxidase, requires the participation of accessory cells. Procedures were developed for the fractionation of rat lymph node cells, by which most of the lymphocytes can be recovered as a major population of cells that do not respond to mitogenic stimulation unless accessory cells from a separated minor population are added. Further purification led to a 1000-fold overall increase in accessory activity per cell, with a 50-70% yield. The purest preparations were virtually free of macrophages and contained more than 90% typical dendritic cells. Maximum responses occurred …


Insulin Degradation By Adipose Tissue. Studies At Several Levels Of Cellular Organization, Barry J. Goldstein, James N. Livingston Feb 1980

Insulin Degradation By Adipose Tissue. Studies At Several Levels Of Cellular Organization, Barry J. Goldstein, James N. Livingston

Department of Medicine Faculty Papers

A systematic study of the degradation of physiological concentrations of 125I-labelled insulin was performed in intact fat-pads, isolated adipocytes and subcellular fractions of isolated adipocytes. The findings indicate that insulin is rapidly degraded to low-molecular-weight peptides and/or amino acids by the intact tissue and isolated cells. Of the total insulin-degradation products present after incubation with an intact fat-pad, 94% is recovered in the medium, indicating that these products are not retained by the cells or tissue. The plasma membranes do not degrade insulin significantly in the absence of reduced glutathione, and over 99% of the cellular degradative capacity is …