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Panel On Arteriosclerosis, William Dock

MCV/Q, Medical College of Virginia Quarterly

Panel on Arteriosclerosis held during the Thirty-Sixth annual McGuire Symposium on Hypertension and Arteriosclerosis, Medical College of Virginia, October 7-9, 1964, moderated by William Dock.

Calender [I.E. Calendar] Of Postgraduate Education

MCV/Q, Medical College of Virginia Quarterly

Calendar of postgraduate education for the Medical College of Virginia, Fall 1965.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 1 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

The Treatment Of Chronic Uremia, Belding H. Scribner

MCV/Q, Medical College of Virginia Quarterly

I will begin by telling a little about the development of chronic dialysis. In 1959 we were working on a system to prevent uremia in acute renal failure. We were trying to develop a system to which we could "hook" the patient for as long as a week, so that we would exactly mimic his normal kidney function during the period of acute renal failure, and make his prognosis that of a patient who had kidneys. The system worked reasonably well. We had to make a lot of modifications, such as using a Skeggs-Leonard dialyzer with low resistance. We used …

The Frequency And Natural History Of Urinary Tract Infection In School Children, Calvin M. Kunin

MCV/Q, Medical College of Virginia Quarterly

This presentation reviews briefly investigations of the epidemiology and natural history of urinary tract infections in school children conducted during the past four years in Central Virginia. The results of this work will be summarized and their implications discussed.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 1 No. 4

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Oxygen Affinities And Electrophoretic Patterns Of Hemoglobins In Trout And Basses From Virginia, Jack D. Burke

MCV/Q, Medical College of Virginia Quarterly

Hemoglobin solutions were prepared from pooled samples of blood taken from each of the following species; Salmo gairdneri, the rainbow trout; Salvelinus fontinalis, the brook trout; Salmo trutta, the brown trout; Micropterus dolomieui, the smallmouth bass; Micropterus salmoides, the largemouth bass. Hemoglobin electrophoretic patterns for each species were developed on cellulose acetate membranes. Oxyhemoglobin affinity curves were determined spectrophotometrically on different hemoglobin solutions from each species. Interspecific differences concerned with hemoglobin electrophoretic patterns, oxyhemoglobin affinities, and the Bohr effect were shown for both trout and basses.

Gastric Secretion Mediated By Extravagal Neural Influences, Charles H. Hockman, Ebbe C. Hoff

MCV/Q, Medical College of Virginia Quarterly

In adult cats anesthetized with ether and immobilized with Flaxedil, the effects of electrical stimulation of cerebral loci on gastric secretion were studied. Stimulation of mesencephalic and diencephalic areas increased both the volume and acidity of samples collected hourly. Section of the spinal cord at the level of the second cervical vertebra abolished this secretion; however, subsequent stimulation in the lateral funiculus of the distal end of the severed cord elicited the response. These pilot studies present further evidence for extravagal mediation of gastric secretion.

Radiologic Diagnosis Of Congenital Heart Disease In Children, Richard G. Lester

MCV/Q, Medical College of Virginia Quarterly

The importance of precise anatomic and physiologic diagnosis in congenital heart disease has been emphasized in recent years, because of the increasing possibilities of surgical correction. The x-ray examination is a powerful tool in the evaluation of patients with congenital heart disease. A method of evaluation is presented, using conventional roentgenographic and fluoroscopic examination along with other simple clinical methods. This approach is relatively simple, can be carried out as an office procedure, and yields a firm clinical diagnosis in the majority of cases. Cardiac catheterization and selective angiocardiography may be necessary to give precise information on physiological abnormalities and …

Contributors To This Issue

MCV/Q, Medical College of Virginia Quarterly

List of contributors to this issue includes Alvan R. Feinstein, Frank A. Finnerty, Jr., Edward David Freis, Walter J. Geeraets, Alice C. Goodman, Louis Homer, A. John Honour, Hermes A. Kontos, Richard G. Lester, Joseph H. Magee, James Franklin Oates, III, Sir George White Pickering, David W. Richardson, Edwin F. Rosinski, Ralph M. Scott, Malcolm E. Turner, and Alton R. Sharpe, Jr.

A New Experimental Approach To The Evaluation Of The Effect Of Narcotic Analgesics Upon Respiratory Function, Charles H. Pierce, Richard B. Mchugh, Raymond N. Bieter

Journal of the Minnesota Academy of Science

Experimental models often used to study the effects of drugs upon respiratory function employ anesthetized animals. The present study eliminated the possible interference of anesthetics by using dogs altered only by a Permanent lracheostomy. Respiratory function was evaluated by determining end-expiratory (alveolar) CO, tension. The experimental design, an extension of the cross-over type, permitted the estimation of possible residual effects of the drugs applied in sequence la the same animals. Morphine Sulfate increasingly caused on elevation in alveolar pCO, while Meperidine HCl had no such effect. An antitussive meperidine derivative, WIN 13187, had respiratory effects similar to meperidine.

Accidental Poisoning In Young Children: Its Causes And Its Prevention, Charles H. Pierce, Harold N. Wright

Journal of the Minnesota Academy of Science

Accidents, burns, drownings, and poisonings are the four most frequent causes of death among children. They far exceed the frequency of death from any of childhood's infectious diseases. With reasonable care, death from poisoning is probably the most amenable to prevention. Accidental poisoning, mainly in preschool children, is discussed from the standpoints of the major toxic hazards found around the usual home, their nature, incidence, location, and prevention.

The Abnormal Coxofemoral Articulation In The German Shepherd Dog, Griselda Hanlon

Journal of the Minnesota Academy of Science

A common abnormality among dogs of the coxofemoral articulation, known as developmental hip dysplasia, is discussed with special reference to its occurrence in the German Shepherd breed. Some observations made from serial radiographic studies of the maturation of normal and abnormal coxofemorol articulation of 200 experimental German Shepherd dogs are presented, and a method of measuring the ilio-acetabular angle is described. Further evaluation will be made of the angle as an early predictor in the course of developmental hip dysplasia.

Virginia Dental Journal (Vol. 42, No. 4, 1965)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 42, No. 3, 1965)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 42, No. 5, 1965)

Virginia Dental Journal

No abstract provided.

The Effect Of Idoxuridine (Idu) On Corneal Stromal Cells In Tissue Culture, Walter J. Geeraets, Guy Wong, Dupont Guerry Iii

MCV/Q, Medical College of Virginia Quarterly

Corneal stromal cells were cultured in vitro and exposed to various concentrations of idoxuridine (IDU), ranging from 0 to 1,000 μg of IDU per ml of medium. Inhibition of cell multiplication occurred with concentrations of 0.1 μg per ml. With concentrations of 1.0 μg per ml and greater, there was no increase in cell number from the time of exposure to IDU.

The Interdependence Of Pulmonary Structure And Function: A Synopsis, Norman C. Staub

MCV/Q, Medical College of Virginia Quarterly

It is a great pleasure to participate in the 1964 Stoneburner lectures and to present some recent views on the structure and function of the lung. In this report I will give a brief summary and show you three pictures to indicate some of the inter-relationships that exist.

Central Nervous Control Of Blood Pressure In Man; Preliminary Report, David W. Richardson, A. J. Honour, A. C. Goodman

MCV/Q, Medical College of Virginia Quarterly

Electrical activity of the brain, eye movements, arterial pressure, heart rate, and respiratory rate and depth have been recorded continuously during a night of sleep not induced by drugs in 22 healthy subjects, two hypertensive patients, and one anephric man who was awaiting renal transplantation. Sleep was associated with reduction in arterial pressure averaging 50 mm Hg systolic and 30 mm Hg diastolic. Dreams, although occasionally associated with marked elevation of blood pressure, were usually accompanied by no change or a slight fall in pressure. The dramatic paroxysmal electroencephalographic alterations termed K complexes, occurring spontaneously or after a noise in …

Γ-Guanidinobutyric Acid: An Inhibitor Of Clot Formation And Of Clot Lysis, Phyllis S. Roberts

MCV/Q, Medical College of Virginia Quarterly

During a study of the effects of a series of guanidine compounds on the esterolytic activities of thrombin, plasmin, and streptokinase plus plasmin or plasminogen, it was found that one of these compunds, γ-guanidinobutyric acid (GGBA), acted in several ways like ε-aminocaproic acid (EACA). Neither compound had any inhibiting effects on the rate of hydrolysis of TAMe (p-toluenesulfonyl-L-arginine methyl ester), but both inhibited the activation of plasminogen by streptokinase. EACA was the more potent inhibitor. Since EACA has been shown to inhibit the lysis of fibrin, primarily because it inhibits the activation of plasminogen (Ablondi et al., 1959, Alkjaersig, Fletcher, …

Panel On The Maintenance Of Life In Uremia, David M. Hume

MCV/Q, Medical College of Virginia Quarterly

Panel on the Maintenance of Life in Uremia held at the Second Annual Kidney Symposium, Virginia Chapter of the National Kidney Disease Foundation, Richmond, October 16, 1964. Moderated by David M. Hume.

Pulmonary Surfactant And Its Relation To Disease, Sami I. Said

MCV/Q, Medical College of Virginia Quarterly

Perhaps the most important advance in respiratory physiology during the past decade is the discovery of the role of surface phenomena. This has been in large measure the result of pioneer work by Pattle, in England, and Clements, in the United States. The following is a simplified and brief review of present knowledge of surface tension, as it relates to normal and abnormal pulmonary function.

Calendar Of Postgraduate Education

MCV/Q, Medical College of Virginia Quarterly

Calendar of postgraduate education for the Medical College of Virginia, Spring 1965.

Books

MCV/Q, Medical College of Virginia Quarterly

Reviews of the following books: Curiosities of Medicine, An Assembly of Medical Diversions, 1552-1962, Berton Roueché, ed.; Body Fluids and the Acid-Base Balance, Halvor N. Christensen; and Respiratory Function in Disease, An Introduction to the Integrated Study of the Lung, David V. Bates and Ronald V. Christie.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 1 No. 1

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Sheep Breeding Problems In W.A. : The Industry's View, Stanley M. Dennis

Journal of the Department of Agriculture, Western Australia, Series 4

IN 1963 a short questionnaire was distributed to farmers and pastoralists seeking information about sheep breeding problems and lamb losses.

This was a fore-runner to the Department of Agriculture survey into the causes of abortion and lamb mortality which is reported elsewhere in this issue.

Pullorum Tested Poultry Flocks, 1965, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

PULLORUM disease has been virtually eliminated from breeding and hatchery poultry flocks in Western Australia by the annual blood-testing of all birds and the destruction of reactors.

Virginia Dental Journal (Vol. 42, No. 1, 1965)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 42, No. 6, 1965)

Virginia Dental Journal

No abstract provided.

The Modern Treatment Of Respiratory Failure, David V. Bates

MCV/Q, Medical College of Virginia Quarterly

I suppose it is appropriate that we come to respiratory failure at the end of a longish day. The definition of respiratory failure has an interesting history. Barcroft, 30 to 40 years ago, understood respiratory failure as a tissue phenomenon. He would have described cyanide poisoning to you as an example of respiratory failure. "Ventilatory failure" came into fashion but is not a very good term because total ventilation may be fine but gas exchange may be very poor. Europeans have invented various terms like "global insufficiency," which sounds very impressive in German, but always sounds to me more like …