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UNO Student Research and Creative Activity Fair

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Full-Text Articles in Medicine and Health Sciences

Effect Of A Passive Exoskeletal Device On Locomotor Adaptive Ability In Healthy Human Subjects, James Nielsen Mar 2017

Effect Of A Passive Exoskeletal Device On Locomotor Adaptive Ability In Healthy Human Subjects, James Nielsen

UNO Student Research and Creative Activity Fair

Background: Functional mobility in stroke survivors is affected by the deterioration in bilateral coordination while walking. A passive exoskeletal device, the Kickstart (Cadence Biomedical, Seattle, WA), that provides assistance during walking may help correct asymmetrical gait patterns by providing different task constraints for each leg during gait training. Methods: 15 healthy young participants walked on a split-belt treadmill where the speed of each belt could be controlled independently. Each participant’s preferred walking speed (PWS), fast walking speed (FWS) and slow walking speed (SWS) was established. Participants then underwent the experimental protocol while either wearing or not wearing the exoskeleton. The …

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Outcomes Of Early Transition From Intravenous To Oral Antimicrobial Treatment In Pediatric Osteomyelitis, Sofia Rahmanzai Mar 2017

Outcomes Of Early Transition From Intravenous To Oral Antimicrobial Treatment In Pediatric Osteomyelitis, Sofia Rahmanzai

UNO Student Research and Creative Activity Fair

The purpose of this clinical study is to determine the effectiveness of the updated treatment for acute osteomyelitis. This treatment plan consists of early transition from intravenous to oral antimicrobial therapy. The efficaciousness of these therapies were compared with post-discharge outcomes and complication rates. This study will utilize patient records during 2011 to 2016 from the University of Nebraska Medical Center and Children’s Hospital and Medical Center. The study includes patients aged from 1 month to 18 years for acute or unspecified osteomyelitis. Excluded patients are children with chronic osteomyelitis, hospitalization of ten or more days, patients with comorbid conditions …

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Construction Of Auxotrophic Strains Of Candida Albicans Clinical Strains, Jenna L. Christiansen Mar 2017

Construction Of Auxotrophic Strains Of Candida Albicans Clinical Strains, Jenna L. Christiansen

UNO Student Research and Creative Activity Fair

Candida albicans is a yeast commonly found in the gastrointestinal and genitourinary tracts of healthy individuals. Although part of the normal human microbiome, C. albicans can be problematic to certain populations such as individuals with compromised immune systems or those taking broad-spectrum antibiotics. C. albicans is the cause of diaper rash, thrush, vaginal yeast infections, and is a leading cause of systemic infections in hospitals. The focus of C. albicans research has almost entirely been focused on a single strain background, SC5314, found in clade I. This research will contribute to a larger project to delete several marker genes (URA3, …

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Meditation As An Intervention For College Students, Ameen Wahba Mar 2017

Meditation As An Intervention For College Students, Ameen Wahba

UNO Student Research and Creative Activity Fair

College students face a variety of stressors and are increasingly susceptible to mental health disorders. Meditation is considered a secular intervention to aid in well-being as well as an aspect of the religious or spiritual experience. In regard to application in daily life, many individuals are unaware of the varieties of meditation available. This work will aim to demystify the practice of meditation in a practical context, specifically focusing its simplicity and lack of cost. Focused Awareness meditation, Open Monitoring Meditation, and Compassion Meditation will be compared and contrasted for their varying benefits in the context of the life of …

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Engagement Of Latino/Hispanic Msm In Hiv Prevention, Natividad Hernandez Mar 2017

Engagement Of Latino/Hispanic Msm In Hiv Prevention, Natividad Hernandez

UNO Student Research and Creative Activity Fair

Nationally, men who have sex with men (MSM) continue to be significantly affected by HIV compared to other populations. Surveillance data indicates that in Nebraska, between 2011 and 2015, over 55% of new HIV cases were MSM.1 More specifically, the majority of new HIV cases in the state of Nebraska are reported in Douglas County.2 The rate of Hispanic Latino males living with an HIV diagnosis is 2.3 times of white males.3 Similarly, the rate of Hispanic/Latina women living with HIV diagnosis is 3.4 times that white females.3 It is important to identify culturally appropriate messages …

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Docking Studies Of Isoform-Selectivity Of Phosphatidylinositol 3-Kinase (Pi3k) Inhibitors, Kaitlin Goettsch Mar 2017

Docking Studies Of Isoform-Selectivity Of Phosphatidylinositol 3-Kinase (Pi3k) Inhibitors, Kaitlin Goettsch

UNO Student Research and Creative Activity Fair

Phosphatidylinositol 3-kinases (PI3Ks) and their related pathways are reputed targets for drug-based anticancer therapies. Mutations in PI3K genes, expression, and pathways are frequent among multiple cancer types. Four isoforms of PI3Ks exist: α, β, γ, & δ and studies have identified several ligands for each isoform which are capable of serving as inhibitory therapeutic compounds. However, the biochemical efficacy of these molecules varies and the isoform selectivity is not well understood. In this study, we applied in silico docking methods and free energy calculation methods to estimate the binding of reported PI3K ligands against 5 PI3K structures: PI3Kα (PBD ID: …

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Range Of Motion And Walking Distances In Subjects With Peripheral Artery Disease, Henamari Ybay Mar 2017

Range Of Motion And Walking Distances In Subjects With Peripheral Artery Disease, Henamari Ybay

UNO Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is caused by blockages in the lower extremity arteries that results in pain during walking known as claudication. Gait variability has emerged as a functional assessment in older and pathological groups1. A healthy gait pattern demonstrates stride-to-stride fluctuations within a certain range of values.2 This study uses standard deviation (SD) and coefficient of variation (CV) to assess the magnitude of variability in the time series. . We compared variability before and after surgery that restores blood flow to the legs of patients with PAD.. Thirty-nine subjects were recruited from the Veteran’s Affairs Medical Center. The setup …

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The Effects Of Walking Speed On Gait Propulsion When Wearing An Ankle-Foot Orthosis, Alli Kalina Mar 2017

The Effects Of Walking Speed On Gait Propulsion When Wearing An Ankle-Foot Orthosis, Alli Kalina

UNO Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is a cardiovascular disease that results from blockage of one or more arteries in the lower extremity. Often, patients with PAD have reduced ability to push off with the foot at the end of the gait cycle. When walking, the ankle contributes the majority of the power to propel the body into the next step. An ankle-foot orthosis (AFO) is a device that aids in ankle propulsion by increasing the energy return, thus decreasing the ankle deficit in pathological individuals. The purpose is to investigate the effect of walking speed on ankle propulsion during walking. Subjects …

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The Effect Of Auditory Stimulation On Human Movement Variability And Associated Cortical Involvement, Samuel Maaiah 9051573 Mar 2017

The Effect Of Auditory Stimulation On Human Movement Variability And Associated Cortical Involvement, Samuel Maaiah 9051573

UNO Student Research and Creative Activity Fair

The Biomechanics Research Building (BRB) is presently using functional near-infrared spectroscopy (fNIRS) to measure and understand brain activity during human movement and exercise. Compared to other brain activity measuring methods, which require subjects to remain very still during recording, fNIRS allows researchers to study brain activity while subjects perform a range of movement tasks. It is consequently a useful tool for studying movements (e.g. walking) that are not conducive to conventional methods of measuring brain activity. Experiments using fNIRS can vary dramatically in duration depending upon the research question. Some experimental methods contain multiple trials for short time intervals, while …

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Modification Of The Ruiz-Moreno Chikungunya Seir Model, Joseph Devlin Mar 2017

Modification Of The Ruiz-Moreno Chikungunya Seir Model, Joseph Devlin

UNO Student Research and Creative Activity Fair

The Ruiez-Moreno CHIKV model predicts the outcome of the Chikungunya disease. Chikungunya, a disease similar to the Zika virus, is vector-borne with very little treatment for patients. This experiment looks to find ways to improve the model. The model will still need further improvement, as there is no model that can predict with full certainty. However, a method of modification has been made to expedite the process, the code has been rearranged for easy input and to minimize possibility of unwanted changes, and the control files for comparison have been created. The method to modify the model can be superimposed …

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Postpartum Physical Activity And Sleep Levels In Overweight And Normal Weight Mothers, Shane Warehime Mar 2017

Postpartum Physical Activity And Sleep Levels In Overweight And Normal Weight Mothers, Shane Warehime

UNO Student Research and Creative Activity Fair

Objective: Objectively examine postpartum mothers’ physical activity (PA) and sleep. Compare PA and sleep of overweight/obese and normal weight postpartum mothers. Setting: A mid-sized city in the Midwestern United States. Participants: Twenty-one mothers who had an infant at least three months old. Participants were classified as normal weight (n = 8) or overweight (n = 13). Methods: PA and sleep levels were gathered for four days at three time intervals in the six months following childbirth. Wrist-worn Actigraph accelerometers were used to collect data. Results: All participants increased PA over time, especially from visit two to visit three. When separated …

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Levodopa-Induced Morot Behavior Alterations In Dosophila Larvae, James Stanton Mar 2017

Levodopa-Induced Morot Behavior Alterations In Dosophila Larvae, James Stanton

UNO Student Research and Creative Activity Fair

Exposing L-Dopa to Drosophila Melanogaster larvae and recording their induced dyskinetic behavior

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