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Articles 1 - 30 of 137
Full-Text Articles in Medicine and Health Sciences
Does Central Corneal Thickness Correlate With Haemoglobin A1c Level And Disease Severity In Diabetes Type Ii?, Mehmet Özgür Zengi̇n, Zeynep Özbek, Gül Arikan, İsmet Durak, Ali̇ Osman Saatci̇
Does Central Corneal Thickness Correlate With Haemoglobin A1c Level And Disease Severity In Diabetes Type Ii?, Mehmet Özgür Zengi̇n, Zeynep Özbek, Gül Arikan, İsmet Durak, Ali̇ Osman Saatci̇
Turkish Journal of Medical Sciences
To compare central corneal thickness (CCT) values of patients with type II diabetes mellitus with those of healthy subjects, and evaluate the effect of disease duration, retinopathy severity, and HbA1c level on CCT. Materials and methods: One hundred and twenty-six consecutive type II diabetic patients and 36 non-diabetic healthy subjects were included in the study. CCT was measured using the Orbscan II corneal topography system. The effect of disease duration, retinopathy severity, and HbA1c level on CCT was evaluated using analysis of variance (ANOVA) and the independent sample t test. Results: CCT was significantly higher in diabetic patients than in …
Serum Prolidase Activity In Patients With Degenerative And Rheumatic Heart Valve Diseases, Murat Bülent Rabuş, Recep Demi̇rbağ, Yusuf Sezen, Mehmet Taşar, Abdullah Taşkin, Nurten Aksoy, Kaan Kirali̇, Cevat Yakut
Serum Prolidase Activity In Patients With Degenerative And Rheumatic Heart Valve Diseases, Murat Bülent Rabuş, Recep Demi̇rbağ, Yusuf Sezen, Mehmet Taşar, Abdullah Taşkin, Nurten Aksoy, Kaan Kirali̇, Cevat Yakut
Turkish Journal of Medical Sciences
It is known that renin-angiotensin system, inflammation, signaling pathways, and genetic predisposition play a major role in the pathogenesis of heart valve disease. Scarring and collagen deposition in the valves and destruction of myocytes may result from the combined effects of rheumatic and degenerative process in heart valve diseases. Prolidase plays an important role in collagen metabolism, matrix remodeling and cell growth. The aim of the study was to comparatively assess the serum prolidase activity in rheumatic and degenerative heart valve diseases. Materials and methods: The study included 26 patients who had undergone valve replacement due to rheumatic etiology (Group …
The Clinical And Polysomnographic Features In Complex Sleep Apnea Syndrome, Handan İnönü, Tansu Ulukavak Çi̇ftçi̇, Oğuz Köktürk
The Clinical And Polysomnographic Features In Complex Sleep Apnea Syndrome, Handan İnönü, Tansu Ulukavak Çi̇ftçi̇, Oğuz Köktürk
Turkish Journal of Medical Sciences
Complex sleep apnea syndrome (CompSAS) is characterized by the onset of central apneas or a Cheyne-Stokes breathing pattern in some patients with obstructive sleep apnea syndrome (OSAS) who were treated with continuous positive airway pressure (CPAP). The etiology of CompSAS is unclear, but derangement of respiratory control has been proposed. We sought to compare clinical and polysomnography (PSG) features of patients with CompSAS and OSAS. Materials and methods: Records of PSG were evaluated in a total of 270 patients, retrospectively. CPAP titration was prescribed in patients with an apnea-hypopnea index (AHI) of >=15. Patients who developed a central AHI of …
Chronic Pain And Depression: A Descriptive Survey Among Adult Primary Health Care Centre Patients, Nüket Paksoy Erbaydar, Nesri̇n Çi̇li̇ngi̇roğlu
Chronic Pain And Depression: A Descriptive Survey Among Adult Primary Health Care Centre Patients, Nüket Paksoy Erbaydar, Nesri̇n Çi̇li̇ngi̇roğlu
Turkish Journal of Medical Sciences
Knowledge of chronic pain and its relationship to depression among primary health care patients in Turkey is inadequate. The aim of this study was to evaluate the frequency of chronic pain and its relationship to depression. Materials and methods: In this descriptive study, data was collected with a questionnaire based on sociodemographic and pain-related characteristics, which was administered to a study population (n = 259) of primary care patients, 18-64 years old. The Visual Analogue Scale (VAS) (min-max = 0-10) and Beck Depression Inventory (BDI) (min-max = 0-63) were used for the assessment of pain severity and depression. Results: Of …
Adrenergic And Cholinergic Responses Of The Tracheal Smooth Muscle Is Enhanced During Estrus Phase In Rat, M. Kasim Çayci, Yasemi̇n Aydin, Kubi̇lay Uzuner
Adrenergic And Cholinergic Responses Of The Tracheal Smooth Muscle Is Enhanced During Estrus Phase In Rat, M. Kasim Çayci, Yasemi̇n Aydin, Kubi̇lay Uzuner
Turkish Journal of Medical Sciences
The aim of this study was to evaluate influences of hormonal changes during rat estrous cycle on airway responsiveness to bronchoconstrictor and bronchodilator agents. Materials and methods: The study was performed in 5 groups of rat tracheal smooth muscle obtained during proestrus, estrus, metestrus, and diestrus phases of the estrous cycle, as well as the ovariectomized group (n:8/group). Cumulative acetylcholine contractions ranging from 10^{-8} to 10^{-3} M bath doses and the cumulative isoproterenol relaxations ranging from 10^{-8} to 10^{-3} M precontracted with 10^{-5} M of acetylcholine were recorded on isolated tracheas placed in a computerized tissue bath system. Results: Acetylcholine-induced …
Effect Of Mechanical Closure Of Dead Space On Seroma Formation In Modified Radical Mastectomy, Ci̇hangi̇r Özaslan, Keri̇m Bora Yilmaz, Lütfi̇ Doğan, Can Atalay, Mehmet Altinok
Effect Of Mechanical Closure Of Dead Space On Seroma Formation In Modified Radical Mastectomy, Ci̇hangi̇r Özaslan, Keri̇m Bora Yilmaz, Lütfi̇ Doğan, Can Atalay, Mehmet Altinok
Turkish Journal of Medical Sciences
Seroma is an important complication of breast surgery. This study investigated the effects of fixation of the flaps and obliterating the dead space on seroma formation. Materials and methods: Patients undergoing modified radical mastectomy were separated into 2 random groups of 50 according to wound closure methods: either flap fixation/mechanical obliteration or standard wound closure group. The fluid that collected under the flaps assessed at the physical examination after the drains were removed was accepted as seroma. The patients' characteristics, duration of the operation, drainage amount, removal time of the drains, flap necroses, and infection were recorded. The groups were …
Comparative Effects Of Levosimendan And Dobutamine Infusion On P Wave Dispersion In Patients With Acute Decompensated Heart Failure, Ati̇la İyi̇soy, Turgay Çeli̇k, Murat Çeli̇k, Bariş Buğan, Hali̇l Yaman
Comparative Effects Of Levosimendan And Dobutamine Infusion On P Wave Dispersion In Patients With Acute Decompensated Heart Failure, Ati̇la İyi̇soy, Turgay Çeli̇k, Murat Çeli̇k, Bariş Buğan, Hali̇l Yaman
Turkish Journal of Medical Sciences
We aimed to evaluate the comparative effects of levosimendan and dobutamine on P-wave dispersion (PWD) in the patients with acute decompensated heart failure (ADHF). Materials and methods: The study population consisted of 40 patients (mean age = 68 years, 23 men, NYHA class III-IV) presented with ADHF. Patients were randomized to intravenous levosimendan (n = 20) or dobutamine (n = 20) groups. The P-wave duration measurements were calculated in 12-lead surface ECG simultaneously and recorded before and after treatment. Manual measurements of P-wave duration were performed with digital calipers on a high resolution computer screen by two cardiologists not aware …
Is The Tanner–Whitehouse (Tw3) Method Sufficiently Reliable For Forensic Age Determination Of Turkish Children?*, Bora Büken, Alp Alper Şafak, Erhan Büken, Burhan Yazici, Zerri̇n Erkol, Ömer Utku Erzengi̇n
Is The Tanner–Whitehouse (Tw3) Method Sufficiently Reliable For Forensic Age Determination Of Turkish Children?*, Bora Büken, Alp Alper Şafak, Erhan Büken, Burhan Yazici, Zerri̇n Erkol, Ömer Utku Erzengi̇n
Turkish Journal of Medical Sciences
The purpose of our study was to determine the accuracy of Tanner-Whitehouse 3 (TW3-RUS) bone age (BA) assessments for forensic age estimations of Turkish children. Materials and methods: Plain radiographs of left hands and wrists of 324 children were evaluated. Mean chronological age (CA) was compared with mean bone age (BA) according to the TW3 atlas for each sex, and differences by age group were determined. Pearson correlation coefficients and cubic regression were used to determine the differences and model the relationships between mean BA and CA. Statistical analyses were carried out using R-project. Results: The difference between the mean …
Endoscopic Biliary Tract Brush Cytology In 54 Cases, Işin Soyuer, Arzu Taşdemi̇r, Şebnem Gürsoy, Alper Yurci̇, Ertuğrul Mavi̇li̇, Nevzat Özcan
Endoscopic Biliary Tract Brush Cytology In 54 Cases, Işin Soyuer, Arzu Taşdemi̇r, Şebnem Gürsoy, Alper Yurci̇, Ertuğrul Mavi̇li̇, Nevzat Özcan
Turkish Journal of Medical Sciences
Duct brushing cytology is an important tool in the evaluation of the extrahepatic biliary tract. New liquid-based preparations and ancillary tests have emerged with the intent of addressing this issue. Materials and methods: Fifty-four consecutive patients and 68 specimens with a suspected malignant obstruction of the common bile duct were included in a consecutive, nonrandomized order. We selected patients whose follow-up, in the form of either histology (25/54, 46%) or at least 6 months of clinical observation, was available. They underwent sampling during ERCP (33 patients/40 materials) or PTC (21 patients/28 materials) using the brush method. Results: A total of …
Feminizing Genitoplasty: An Evaluation Of 41 Patients In 8 Years, Fati̇h Akbiyik, Hüseyi̇n Tuğrul Ti̇ryaki̇, Emrah Şenel, Ervi̇n Mambet, Yusuf Zi̇ya Li̇vaneli̇oğlu, Hali̇l Faruk Atayurt
Feminizing Genitoplasty: An Evaluation Of 41 Patients In 8 Years, Fati̇h Akbiyik, Hüseyi̇n Tuğrul Ti̇ryaki̇, Emrah Şenel, Ervi̇n Mambet, Yusuf Zi̇ya Li̇vaneli̇oğlu, Hali̇l Faruk Atayurt
Turkish Journal of Medical Sciences
The authors present early results of feminizing genitoplasty procedures. Materials and methods: Medical records of 41 patients who underwent feminizing genitoplasty in between 2001 and 2009 were evaluated retrospectively. Results: Follow-up period was 1 month to 7.5 years. Clitorolabial cosmesis was good in all patients except one. Neither clitoral necrosis nor enlargement was noted in postoperative period. The most common complication observed was vaginal stenosis. For 7 patients with severe stenosis, reoperations are planned at puberty. Conclusion: One-stage or staged genitoplasty is performed for disorders of sexual development (DSD) patients. Although results of clitoroplasty are satisfactory, reoperation rates due to …
Two Siblings With Netherton Syndrome, Selma Emre, Ahmet Meti̇n, D. Deni̇z Demi̇rseren, Ahu Yorulmaz, Aykut Onursever, Burçi̇n Kaftan
Two Siblings With Netherton Syndrome, Selma Emre, Ahmet Meti̇n, D. Deni̇z Demi̇rseren, Ahu Yorulmaz, Aykut Onursever, Burçi̇n Kaftan
Turkish Journal of Medical Sciences
Netherton syndrome (NS) is a rare genodermatosis characterized by autosomal recessive inheritance pattern, unknown etiology, ichthyosiform cutaneous changes, atopic diathesis, and alterations in the hair shaft. As a result of aging coupled with immune deficiency, clinical symptoms may vary. Herein, we present 2 siblings with the characteristic cutaneous symptoms of NS, albeit with some differences between the siblings. Materials and methods: Two sisters presented to our clinic with sparse and brittle hair along with pruritic, erythematous, and scaling cutaneous lesions. Both patients underwent a clinical examination and laboratory analyses. Results: Based on the clinical and laboratory findings, both patients were …
The Association Of Tafi (Thrombin-Activatable Fibrinolysis Inhibitor) With Insulin Resistance And Components Of Metabolic Syndrome In Patients With Metabolic Syndrome, Alev Kural, Ahmet Omma, Hati̇ce Seval, Maci̇t Koldaş, Namik Yi̇ği̇t, Tülay Omma
The Association Of Tafi (Thrombin-Activatable Fibrinolysis Inhibitor) With Insulin Resistance And Components Of Metabolic Syndrome In Patients With Metabolic Syndrome, Alev Kural, Ahmet Omma, Hati̇ce Seval, Maci̇t Koldaş, Namik Yi̇ği̇t, Tülay Omma
Turkish Journal of Medical Sciences
To investigate the association of TAFI with components of metabolic syndrome and insulin resistance in patients with metabolic syndrome. Materials and methods: Patients between 20 and 70 years of age, who met at least 3 of the metabolic syndrome criteria, and had no known coronary artery disease were included in the study. The control group consisted of 20 healthy subjects with demographic characteristics similar to the patients. Fasting blood glucose, HbA1c, lipid profile, insulin, microalbumin, and TAFI Ag levels were investigated in the patients and controls. Insulin resistance was calculated according to the HOMA-IR [(fasting plasma insulin (\muIU/ml) x fasting …
Vitamin C Modulates Oxidative Stress-Induced Colitis In Rats, Mustafa Zeri̇n, Ali̇ Zi̇ya Karakilçik, Muharrem Bi̇ti̇ren, Davut Musa, Abdullah Özgönül, Şehabetti̇n Selek, Yaşar Nazligül, Ali̇ Uzunköy
Vitamin C Modulates Oxidative Stress-Induced Colitis In Rats, Mustafa Zeri̇n, Ali̇ Zi̇ya Karakilçik, Muharrem Bi̇ti̇ren, Davut Musa, Abdullah Özgönül, Şehabetti̇n Selek, Yaşar Nazligül, Ali̇ Uzunköy
Turkish Journal of Medical Sciences
Free radicals are an important factor in the etiopathogenesis of colitis and may increase oxidative damage. The antioxidant vitamin C efficiently scavenges free oxygen radicals. The present study aimed to investigate the probable protective effects of vitamin C on oxidative injury in rats in which colitis was experimentally induced with acetic acid. Materials and methods: This study was conducted with rats for a period of 7 days. Group 1 intrarectally received a placebo (0.9% NaCl) and group 2 intrarectally received 2 mL of 5% acetic acid (AA) and the placebo. Group 3 intrarectally received 2 mL of 5% AA and …
Dermatoglyphics As Markers Of Prenatal Disturbances In Schizophrenia: A Case-Control Study, Bi̇rsen Özyurt, Ahmet Songur, Mustafa Sarsilmaz, Ömer Akyol, Mustafa Namli, Reha Demi̇rel
Dermatoglyphics As Markers Of Prenatal Disturbances In Schizophrenia: A Case-Control Study, Bi̇rsen Özyurt, Ahmet Songur, Mustafa Sarsilmaz, Ömer Akyol, Mustafa Namli, Reha Demi̇rel
Turkish Journal of Medical Sciences
Several studies have reported the importance of dermatoglyphics as markers of a prenatal disturbance in patients with schizophrenia. Due to the fact that finger- and handprints are formed by the end of the second trimester, they may provide clues to disturbances in early development. The aim of this study was to determine specific dermatoglyphical frequencies in a sample of patients with schizophrenia and normal controls. Materials and methods: Fingerprints and palm prints were obtained from 45 schizophrenic patients as well as 45 healthy controls. The dermatoglyphic patterns on the fingers (total finger ridge count [TFRC]) and palms (a-b, b-c, and …
The Effect Of Caffeic Acid Phenethyl Ester On Bacterial Translocation And Intestinal Damage After Intestinal Obstruction, Cengi̇z Ara, Abuzer Di̇ri̇can, Seli̇m Erdoğan, Burhan Ateş, Di̇nçer Özgör, Fai̇k Tatli, M. Sai̇t Tekerekoğlu, Vedat Kirimlioğlu
The Effect Of Caffeic Acid Phenethyl Ester On Bacterial Translocation And Intestinal Damage After Intestinal Obstruction, Cengi̇z Ara, Abuzer Di̇ri̇can, Seli̇m Erdoğan, Burhan Ateş, Di̇nçer Özgör, Fai̇k Tatli, M. Sai̇t Tekerekoğlu, Vedat Kirimlioğlu
Turkish Journal of Medical Sciences
Intestinal obstruction (IO) induces bacterial translocation due to failure of the intestinal barrier function. Following bacterial overgrowth, its degradation products play a decisive role in the development of systemic septic complications. The aim of this study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) on bacterial translocation and intestinal damage in an IO model in rats. Materials and methods: Complete IO was created in the distal ileum of rats by a single 4-0 silk suture. A total of 21 Wistar albino rats were randomized into 3 groups: Group 1, Sham (n = 7); Group 2, IO (n …
Evaluation Of Coping Strategies, Social Support, And Depressive Symptoms In Spouses Of Patients With Hematological Cancer, Safi̇ye Özkan, Yasemi̇n Kutlu
Evaluation Of Coping Strategies, Social Support, And Depressive Symptoms In Spouses Of Patients With Hematological Cancer, Safi̇ye Özkan, Yasemi̇n Kutlu
Turkish Journal of Medical Sciences
The purpose of this study was the evaluation of coping strategies, social support, and depressive symptoms in spouses of patients with hematological cancer. Materials and methods: A descriptive design was used in current study. The study was carried out at the hematology clinic of 2 university hospitals located in İstanbul. The convenience sample consisted of 150 spouses of patients who had hematological cancer. The data were collected through structured face-to-face interviews using a questionnaire form, the "Ways of Coping" Questionnaire, the Multidimensional Perceived Social Support Scale, and Beck Depression Inventory. Percentage t-tests and Pearson's product moment correlation were used to …
Histomorphometric Study On The Effect Of Low Dose Deltamethrin On The Developing Cerebellar Cortex, Mohd Asnizam Asari, Mohammad Shukri Abdullah, Zul Izhar Mohd Ismail
Histomorphometric Study On The Effect Of Low Dose Deltamethrin On The Developing Cerebellar Cortex, Mohd Asnizam Asari, Mohammad Shukri Abdullah, Zul Izhar Mohd Ismail
Turkish Journal of Medical Sciences
Deltamethrin is a widely used type II pyrethroid-based insecticide. Studies have indicated that neonatal exposure to deltamethrin, even at relatively low doses, results in behavioral and neurological changes. In the present study, the effect of early neonatal exposure to low doses of deltamethrin on the histogenesis of the cerebellar cortex was investigated. Materials and methods: Sprague Dawley male pups were exposed to deltamethrin daily at a dose of 1 mg/kg via intraperitoneal injection from the 2nd to the 5th postnatal day and sacrificed on postnatal days 6, 14, and 21. Following intracardiac perfusion, the cerebellum was removed, embedded with paraffin …
Prevalence Of Helicobacter Pylori Infection In Healthcare Workers, Maliheh Metanat, Batool Sharifi-Mood, Shahrokh Izadi
Prevalence Of Helicobacter Pylori Infection In Healthcare Workers, Maliheh Metanat, Batool Sharifi-Mood, Shahrokh Izadi
Turkish Journal of Medical Sciences
Helicobacter pylori (H. pylori) is a major factor in inflammatory and malignant diseases of the gastrointestinal tract. The epidemiologic pattern of this infection varies among developed and developing countries, and is related to the general standards of living in each region. In view of the importance of this infection and its different prevalence in different regions of Iran, as well as its long-term complications, this study was conducted to investigate the prevalence of H. pylori infection and its contributing factors in Zahedan. Materials and methods: Ninety-seven healthcare workers without digestive symptoms or a history of H. pylori eradication were randomly …
The Prevalence Of Trichomonas Vaginalis Infection Among Patients That Presented To Hospitals In The Kermanshah District Of Iran In 2006 And 2007, Abdolali Chalechale, Isaac Karimi
The Prevalence Of Trichomonas Vaginalis Infection Among Patients That Presented To Hospitals In The Kermanshah District Of Iran In 2006 And 2007, Abdolali Chalechale, Isaac Karimi
Turkish Journal of Medical Sciences
To determine the prevalence of Trichomonas vaginalis (Tv) among women that presented to hospitals in the Kermanshah district of Iran in 2006 and 2007. Materials and methods: This retrospective study included 33.690 women that presented to primary pathology laboratories in Kermanshah. Vaginal and cervical swabs were collected, and then stained with Papanicolaou (Pap) stain. Additionally, seasonal variations in the prevalence rate were compared to identify significant differences in the prevalence of Tv according to season. Results: Among the 33,690 women, 300 were infected with Tv (a prevalence rate of 0.9%). The 30-39-year-old age group had a significantly higher prevalence of …
Atypical Clinical Manifestation Of Dementia: A Progressive Visuospatial Deficit, Mehmet Güney Şenol, Hakan Tekeli̇, Erdem Toğrol, Mehmet Saraçoğlu
Atypical Clinical Manifestation Of Dementia: A Progressive Visuospatial Deficit, Mehmet Güney Şenol, Hakan Tekeli̇, Erdem Toğrol, Mehmet Saraçoğlu
Turkish Journal of Medical Sciences
Clinically and neuropathologically dementia is a very heterogeneous disease. Alzheimer's disease (Alzheimer disease, AD), the most common cause of dementia, is an acquired cognitive and behavioral impairment of sufficient severity that markedly interferes with social and occupational functioning. This disease may be manifested as progressive memory problems, visuospatial deterioration, aphasia and/or deficits of executive functions. The patient we report here is a 73-year-old female patient with loss of ability of finding directions and understanding the shapes of materials. Her complaints increased progressively during the last two years. Even if she had retired from tailoring, she had deterioration in the visuospatial …
Underlying Diseases Of Recurrent Pneumonia In Turkish Children*, Osman Özdemi̇r, Si̇nan Sari, Arzu Bakirtaş, Peli̇n Zorlu, Ülker Ertan
Underlying Diseases Of Recurrent Pneumonia In Turkish Children*, Osman Özdemi̇r, Si̇nan Sari, Arzu Bakirtaş, Peli̇n Zorlu, Ülker Ertan
Turkish Journal of Medical Sciences
The aim of the present study was to determine the relative frequency of recurrent pneumonia in children and to describe its underlying illnesses. Materials and methods: Children between 3 months and 16 years old who had a history of 2 or more episodes of pneumonia per year, or 3 or more episodes in a lifetime were investigated retrospectively at Doctor Sami Ulus Children's Training and Research Hospital between January 2002 and December 2004. Results: Out of 595 children admitted for pneumonia, 62 (10.42%) met the criteria for recurrent pneumonia. An underlying illness was demonstrated in 56 patients (90.32%). In this …
The Effects Of Adding Methylprednisolone To Low-Potassium Dextran Solution On Preserved Ischemic Lungs, Ali̇ Yegi̇nsu, Makbule Ergi̇n, Hüseyi̇n Özyurt, Çi̇ğdem Elmas, Güleser Çağlar Göktaş
The Effects Of Adding Methylprednisolone To Low-Potassium Dextran Solution On Preserved Ischemic Lungs, Ali̇ Yegi̇nsu, Makbule Ergi̇n, Hüseyi̇n Özyurt, Çi̇ğdem Elmas, Güleser Çağlar Göktaş
Turkish Journal of Medical Sciences
To investigate the effects of adding methylprednisolone to low-potassium dextran solution on cold-preserved ischemic lungs. Materials and methods: The study included 42 rat lung blocks that were divided into 7 groups (n = 6). Lung blocks were preserved in 40 mL of cold Perfadex solution, to which 5, 15, 30, 60, and 120 mg kg-1 (approximately 40, 120, 240, 480, and 960 mg L-1) of methylprednisolone were added. After a 24-h preservation period, the lungs were removed from the solution and examined. Results: As compared to the Perfadex only group, cell death and degeneration were significantly higher in the Perfadex …
Comparison Of Serum Levels Of Il-6, Il-8, Tnf-Α, C Reactive Protein And Heat Shock Protein 70 In Patients With Active Or Inactive Behçet’S Disease, Remzi̇ Karadağ, Cemi̇le Koca, Yüksel Totan, Ramazan Yağci, Murat Aydin, Ayşe Serap Karadağ, Celi̇le Gülfer Akbay, Hati̇ce Meral Ekşi̇oğlu, Muhammet Ramazan Yi̇ği̇toğlu
Comparison Of Serum Levels Of Il-6, Il-8, Tnf-Α, C Reactive Protein And Heat Shock Protein 70 In Patients With Active Or Inactive Behçet’S Disease, Remzi̇ Karadağ, Cemi̇le Koca, Yüksel Totan, Ramazan Yağci, Murat Aydin, Ayşe Serap Karadağ, Celi̇le Gülfer Akbay, Hati̇ce Meral Ekşi̇oğlu, Muhammet Ramazan Yi̇ği̇toğlu
Turkish Journal of Medical Sciences
The aim of this study was to elucidate serum levels of IL-6, IL-8, TNF-\alpha, CRP, and HSP 70 in patients with active or inactive Behçet's disease. Materials and methods: The study included 50 patients who met the International Study Group criteria for Behçet's disease. Of these, 26 had active disease and 24 had inactive disease. The control group was comprised of 25 age- and sex-matched healthy participants. Serum levels of IL-6, IL-8, TNF-\alpha, CRP, and HSP 70 were measured. Results: In patients with active disease, significantly higher mean serum levels of IL-6, IL-8, TNF-\alpha, and CRP were found compared to …
The Effect Of Intradialytic Food Intake On The Urea Reduction Ratio And Single-Pool Kt/V Values In Patients Followed-Up At A Hemodialysis Center*, Belgüzar Kara, Cengi̇z Han Açikel
The Effect Of Intradialytic Food Intake On The Urea Reduction Ratio And Single-Pool Kt/V Values In Patients Followed-Up At A Hemodialysis Center*, Belgüzar Kara, Cengi̇z Han Açikel
Turkish Journal of Medical Sciences
This study was conducted to determine the effect of intradialytic food intake on the urea reduction rate (URR) and single-pool Kt/V (spKt/V) values in hemodialysis (HD) patients. Materials and methods: The study was designed as a quasiexperiment. Twenty-five patients were enrolled in this study. The patients' mean age was 56.5 ± 13.0 years and median time on HD was 63 months. In the first stage of the study, patients were given a standard meal after the first hour of the treatment. The same study group underwent HD without intradialytic food intake 1 week later. Predialysis and postdialysis blood samples for …
Nitric Oxide And Trace Metals In Relation To Haemoglobin F Concentration In Nigerian Sickle Cell Disease Patients, John Ayodele Olaniyi, Olatubosun Ganiyu Arinola
Nitric Oxide And Trace Metals In Relation To Haemoglobin F Concentration In Nigerian Sickle Cell Disease Patients, John Ayodele Olaniyi, Olatubosun Ganiyu Arinola
Turkish Journal of Medical Sciences
Sickle cell disease (SCD) is an inherited haemoglobin (Hb) disorder associated with vaso-occlusive events, oxidative stress, high energy demand, and endothelial dysfunction. The endothelium plays a central role in the regulation of vascular homeostasis by releasing nitric oxide (NO) among other factors. Therefore, the objective of this study was to measure plasma levels of NO, trace metals, and HbF in SCD patients. Materials and methods: Plasma levels of NO, Zn, Mg, Mn, Se, Cu, Fe, Haemoglobin F (HbF) were measured in 59 steady state SCD patients referred to the Department of Haematology, University College Hospital, Ibadan, Nigeria and 35 age/sex …
Familial Amyloidosis Cutis Dyschromica, Ayşe Serap Karadağ, Gülçi̇n Güler Şi̇mşek
Familial Amyloidosis Cutis Dyschromica, Ayşe Serap Karadağ, Gülçi̇n Güler Şi̇mşek
Turkish Journal of Medical Sciences
Primary cutaneous amyloidosis is a rare progressive disease that is characterized with the deposition of amyloid under the skin instead of internal organs. Major types are the macular, papular, nodular types. Amyloidosis cutis dyschromica is a very rare specific type of vitiliginous amyloidosis. A 16 year-old female patient and 22 year-old male patient, siblings, referred to the hospital with the complaint of non-pruritic diffuse hyperpigmentation beginning from trunk and spreading to all body. The histopathologic findings and crystal violet stain were consistent with amyloidosis cutis dyschromica. All other investigations were normal. There are few reported cases related with this amyloidosis …
Cancer And Ovarian Tissue Cryopreservation, Yavuz Emre Şükür, Batuhan Özmen, Murat Sönmezer
Cancer And Ovarian Tissue Cryopreservation, Yavuz Emre Şükür, Batuhan Özmen, Murat Sönmezer
Turkish Journal of Medical Sciences
Although ovarian tissue cryopreservation is still accepted as an experimental procedure, it has recently become an increasingly resorted technique in highly specialized in vitro fertilization (IVF) clinics. Its indications include many childhood cancers, breast cancer, some autoimmune diseases, hematopoietic stem cell transplantation, and pelvic radiation therapy due to solid tumors. The chemotherapeutics and radiation therapy may diminish ovarian reserve and cause premature ovarian failure. It currently seems as the only option for fertility preservation in children where ovulation induction is ethically not acceptable, and for those when cytotoxic therapy is urgent. There are 2 main methods for transplantation of frozen-thawed …
Small-For-Gestational-Age Newborns Need A Special Fluid Therapy Strategy, Alparslan Tonbul, Cüneyt Tayman, Ahmet Karadağ, Hali̇se Akça, Nurdan Uras, Mustafa Mansur Tatli
Small-For-Gestational-Age Newborns Need A Special Fluid Therapy Strategy, Alparslan Tonbul, Cüneyt Tayman, Ahmet Karadağ, Hali̇se Akça, Nurdan Uras, Mustafa Mansur Tatli
Turkish Journal of Medical Sciences
To determine the fluid requirement of small-for-gestational-age (SGA) newborns and to compare them with that of appropriate for gestational age (AGA) newborns in the first 5 days of life. Materials and methods: The present study was conducted from January 2007 to August 2007, including newborns with a gestation age of 32-40 weeks, with respiratory problems, feeding problems, and prematurity, and required intravenous fluid for at least 3 days. Two study groups were established: SGA (group 1) and AGA (group 2) according to the Lubchenco scale. All newborns were cared at an ambient humidity of 40% in an incubator and received …
Serum Nitric Oxide And Peroxynitrite Levels In Adult Sero-Positive Rheumatoid Arthritis Treated With Disease Modifying Antirheumatic Drugs: A Preliminary Report, Marwan S.M. Al-Nimer, Samir Abdul-Hassan Al-Obaidi, Khalid S. Al-Dulaimi
Serum Nitric Oxide And Peroxynitrite Levels In Adult Sero-Positive Rheumatoid Arthritis Treated With Disease Modifying Antirheumatic Drugs: A Preliminary Report, Marwan S.M. Al-Nimer, Samir Abdul-Hassan Al-Obaidi, Khalid S. Al-Dulaimi
Turkish Journal of Medical Sciences
The contribution of inducible nitric oxide synthase (iNOS) to oxidative/nitrative stress is well documented in inflamed joints. Nitric oxide stimulates the synthesis of proinflammatory mediators and cytotoxic molecules with a pivotal role in apoptosis at the joint of rheumatoid arthritis. This study aimed to assess the serum levels of nitric oxide and peroxynitrite in sero positive rheumatoid patients treated with disease modifying antirheumatic drugs. Materials and methods: Sixteen known patients with sero-positive rheumatoid arthritis fulfilling the criteria of the American College of Rheumatology and on disease modifying antirheumatic drugs were allocated from the consultant clinic of rheumatology at Al-Yarmouk Teaching …
Assessment Of Procalcitonin And Other Inflammatory Markers In Peritoneal Dialysis-Related Peritonitis*, Reyhan Öztürk, Gül R. Yilmaz, Cemal Bulut, Hülya Parpucu, Sami̇ Kinikli, Murat Duranay, Ali̇ Pekcan Demi̇röz
Assessment Of Procalcitonin And Other Inflammatory Markers In Peritoneal Dialysis-Related Peritonitis*, Reyhan Öztürk, Gül R. Yilmaz, Cemal Bulut, Hülya Parpucu, Sami̇ Kinikli, Murat Duranay, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
It is demonstrated that in end-stage renal failure without an infectious pathology conventional laboratory parameters such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) or other acute-phase proteins increase non-specifically. We aimed to evaluate procalcitonin (PCT) and other inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in patients with continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis. Materials and methods: A case-control study was conducted in a 600-bed tertiary hospital. Fifty patients with CAPD-related peritonitis constituting the study group and 50 CAPD patients without infection as the control group were included in the study between February 2006 …