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Articles 1 - 30 of 73
Full-Text Articles in Medicine and Health Sciences
Antioxidants And Pain Control In Patients With Chronic Pancreatitis: A Never-Ending Story, Raffaele Pezzilli, Lorenzo Fantini
Antioxidants And Pain Control In Patients With Chronic Pancreatitis: A Never-Ending Story, Raffaele Pezzilli, Lorenzo Fantini
Turkish Journal of Medical Sciences
Chronic pancreatitis is a benign disease often characterized by recurrent episodes of abdominal pain accompanied by progressive pancreatic exocrine and endocrine insufficiency; it sometimes requires multiple hospitalizations. This disease is frequently the result of chronic alcohol abuse, even if other factors such as genetic alterations, autoimmune disorders, and obstructive disease of the biliary tract and the pancreas may cause the disease. The pain can be considered the most important symptom; it significantly modifies the quality of life of patients with chronic pancreatitis and its control represents a challenge in the treatment of the disease. Among the several modalities for controlling …
The Frequency Of Ccr5delta32 Polymorphism In The Central Black Sea Coastal Region In A Healthy Population, Sezgi̇n Özgür Güneş, Nurten Kara, Hasan Bağci
The Frequency Of Ccr5delta32 Polymorphism In The Central Black Sea Coastal Region In A Healthy Population, Sezgi̇n Özgür Güneş, Nurten Kara, Hasan Bağci
Turkish Journal of Medical Sciences
Aim: Delta32 polymorphism in the chemokine receptor 5 (CCR5) gene affects human immune deficiency virus type 1 (HIV-1) entry, transmission, and outcome. The aim of this study was to determine the allelic frequencies of genetic variant CCR5delta32, which influence susceptibility to HIV-1 infection, in a northern Turkish population. Materials and Methods: We determined the allelic frequencies of CCR5delta32 in 449 unrelated healthy individuals from the central Black Sea coastal region without any known history of HIV-1 infection. The polymorphism was analyzed using polymerase chain reaction (PCR). The population was in the Hardy-Weinberg equilibrium. Delta32 allelic frequencies were calculated. Results: The …
Risk Factors For Fecal Carriage Of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli And Klebsiella Spp. In The Community, Özlem Kurt Azap, Hande Arslan, Sedef Ö. Karaman, Turhan Togan
Risk Factors For Fecal Carriage Of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli And Klebsiella Spp. In The Community, Özlem Kurt Azap, Hande Arslan, Sedef Ö. Karaman, Turhan Togan
Turkish Journal of Medical Sciences
Aim: Community-acquired infections caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria are an emerging problem. Digestive tract colonization is a prerequisite for infections by ESBL-producing microorganisms. The aim of this study was to determine the prevalence of and risk factors for fecal carriage of ESBL-producing Escherichia coli (E. coli) or Klebsiella spp. in the community. Materials and Methods: A total of 928 stool samples admitted to the laboratory during a four-month period were included in the study. Samples were diluted in saline and cultured in two EMB agar plates supplemented with either 1 µg/ml cefotaxime or 1 µg/ml ceftazidime. All isolates that …
The Role Of Periodontal Disease On Acute Phase Proteins In Patients With Coronary Heart Disease And Diabetes, Gonca Çayir Keleş, Burcu Özkan Çeti̇nkaya, Selen Burçak Şi̇mşek, Di̇yar Köprülü, Hakki Kahraman
The Role Of Periodontal Disease On Acute Phase Proteins In Patients With Coronary Heart Disease And Diabetes, Gonca Çayir Keleş, Burcu Özkan Çeti̇nkaya, Selen Burçak Şi̇mşek, Di̇yar Köprülü, Hakki Kahraman
Turkish Journal of Medical Sciences
Aims: Chronic infections such as periodontal disease (PD) have been suggested to be a risk factor for coronary heart disease (CHD). Elevated levels of acute phase proteins are associated with increased risk for cardiovascular events in both healthy individuals and patients with known CHD. This study aimed to investigate the role of PD on C-reactive protein (CRP) and fibrinogen levels in patients with either CHD or type 2 diabetes. Materials and Methods: 80 subjects were evaluated in four groups: individuals with CHD+PD (group 1; n: 20), individuals with type 2 diabetes+PD (group 2; n: 20), individuals with PD without any …
Water Sorption And Solubility Of Different Luting And Restorative Dental Cements, Fi̇li̇z Keyf, S. Hakan Tuna, Murat Şen, Agnes Safrany
Water Sorption And Solubility Of Different Luting And Restorative Dental Cements, Fi̇li̇z Keyf, S. Hakan Tuna, Murat Şen, Agnes Safrany
Turkish Journal of Medical Sciences
Aim: The purpose of this study was to compare the water sorption and solubility of four provisional, three permanent luting cements and five restorative cements. Methods: A split ring mould was fabricated for the preparation of specimen discs which were 15.0 mm in diameter and 1.5 mm thick. All specimens were manipulated according to the manufacturer's instructions and then subjected to water sorption and solubility tests. Data were analysed with Wilcoxon Signed Ranks Test. Scanning electron microscopy was used to evaluate surface topography and roughness. Results: All tested materials demonstrated different degrees of sorption and solubility. The difference between sorption …
The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden
The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden
Turkish Journal of Medical Sciences
Aim: To investigate the clinical implications of serum heart-type fatty acid-binding protein (H-FABP) compared to myoglobin, cardiac troponin I (cTnI), and creatine kinase MB isoenzyme (CK-MB) in patients with early phase acute myocardial infarction (AMI). Material and Methods: Patients were grouped clinically according to the American College of Cardiology/European Society of Cardiology new definition of myocardial infarction (MI) and by clinician diagnosis of MI. Serum concentrations of H-FABP, myoglobin, cTnI, and CK-MB were determined in 21 patients with AMI and 44 non-AMI patients. From each patient 3 blood samples were obtained 1-2, 3, and 6 h after the onset chest …
Comparison Of Conventional Cytogenetic And Fluorescence In Situ Hybridization Results Of Prenatal Aneuploidy Screening, Zerri̇n Yilmaz, Özge Özalp, Ebru Tarim, Ayla Üçkuyu, Vural Dağli, Feri̇de İffet Şahi̇n
Comparison Of Conventional Cytogenetic And Fluorescence In Situ Hybridization Results Of Prenatal Aneuploidy Screening, Zerri̇n Yilmaz, Özge Özalp, Ebru Tarim, Ayla Üçkuyu, Vural Dağli, Feri̇de İffet Şahi̇n
Turkish Journal of Medical Sciences
Background and Aim: Prenatal diagnosis of chromosome abnormalities is usually performed on amniotic fluid samples. Aneuploidy screening by fluorescence in situ hybridization (FISH), although not an alternative for conventional cytogenetics, has become a useful tool. Materials and Methods: We compared the results of FISH and conventional cytogenetic analysis applied on 51 amniotic fluid samples between January 2002 and December 2005, in our Cytogenetics Laboratory. Amniocytes were extracted using 5 cc of the sample, and direct FISH was applied using an AneuVysion Assay Kit (Vysis). The remaining fluid samples were used for chromosome analysis by conventional methods after long-term cell cultures. …
Ghrelin May Be A Universal Peptide In All Living Organisms, Süleyman Aydin
Ghrelin May Be A Universal Peptide In All Living Organisms, Süleyman Aydin
Turkish Journal of Medical Sciences
No abstract provided.
Correlations Of Serum Il-6 Levels And Prolidase Activity Between Bone Turnover Markers And Bone Mineral Density In Postmenopausal Women With And Without Osteoporosis, Aysun Toker, Hülya Aksoy, Bünyami̇n Börekçi̇, Asuman Özkan
Correlations Of Serum Il-6 Levels And Prolidase Activity Between Bone Turnover Markers And Bone Mineral Density In Postmenopausal Women With And Without Osteoporosis, Aysun Toker, Hülya Aksoy, Bünyami̇n Börekçi̇, Asuman Özkan
Turkish Journal of Medical Sciences
Aim: The purpose of this study was to measure serum prolidase activity and interleukin-2 and 6 (IL-2, IL-6) levels and to investigate the relationship of these parameters with bone mineral density (BMD) and bone turnover markers in postmenopausal women with and without osteoporosis. Materials and Methods: 59 postmenopausal women were included in this study (21 women with osteoporosis and 38 without). Serum IL-2 and IL-6 levels, prolidase activity, osteocalcin (OSC), calcium (Ca), alkaline phosphatase (ALP), urinary deoxypyridinoline (DPD) and BMD were measured in postmenopausal women with and without osteoporosis. Results: Serum prolidase activity was slightly higher in postmenopausal nonosteoporotic women …
A Role Of Leptin In Psoriasis?, Şebnem Aktan, Si̇mi̇n Rota, Berna Şanli Erdoğan, Şeni̇z Ergi̇n, Bünyami̇n Kaptanoğlu, Mehmet Bostanci
A Role Of Leptin In Psoriasis?, Şebnem Aktan, Si̇mi̇n Rota, Berna Şanli Erdoğan, Şeni̇z Ergi̇n, Bünyami̇n Kaptanoğlu, Mehmet Bostanci
Turkish Journal of Medical Sciences
Aim: Although there is evidence of a positive association between psoriasis and body mass index (BMI) and leptin is known to play a part in the regulation of the immune system, the relationship between psoriasis and leptin is still not well known. The aim of this study was to evaluate the possible relation between leptin and psoriasis. Materials and Methods: Serum leptin concentrations and BMI in 20 patients with psoriasis were compared to 20 age- and sex-matched healthy volunteers. Results: There was no difference between serum leptin levels of psoriatic patients (32.3 ± 24.9 ng/ml) and controls (36.8 ± 28.2 …
Cobalamin Deficiency During Pregnancy Expressed As Elevated Urine Methylmalonic Acid Levels Determined By A Photometric Assay, Osman Meti̇n İpçi̇oğlu, Mustafa Gültepe, Ömer Özcan
Cobalamin Deficiency During Pregnancy Expressed As Elevated Urine Methylmalonic Acid Levels Determined By A Photometric Assay, Osman Meti̇n İpçi̇oğlu, Mustafa Gültepe, Ömer Özcan
Turkish Journal of Medical Sciences
Aim: Deficiency of cobalamin and folate during pregnancy is associated with megaloblastic anemia. Lower levels of folate and vitamin B12 were reported in mothers whose offspring had neural tube defects compared to unaffected controls. Increased methylmalonic acid (MMA) levels are a sensitive indicator of mild vitamin B12 deficiency and elevated homocysteine levels denote vitamin B12 or folate deficiency. We aimed to evaluate cobalamin state in pregnancy by using urine MMA levels determined by an economic spectrophotometric method. Materials and Methods: For this cross-sectional study, plasma total homocysteine (tHcy), serum folate and vitamin B12, and urine MMA levels were measured in …
Giant Hydronephrosis Mimicking An Intraabdominal Mass, Turgut Yapanoğlu, Fati̇h Alper, İsa Özbey, Yilmaz Aksoy, Azam Demi̇rel
Giant Hydronephrosis Mimicking An Intraabdominal Mass, Turgut Yapanoğlu, Fati̇h Alper, İsa Özbey, Yilmaz Aksoy, Azam Demi̇rel
Turkish Journal of Medical Sciences
Giant hydronephrosis (GH) is a rare entity that may mimic progressive and benign abdominal cystic tumors. Despite the increase in the use of prenatal ultrasound, GH may still be seen in the adult population. We report a case of GH in a 19-year-old female who presented with a progressive abdominal distention and other gastrointestinal symptoms. Diagnostic and therapeutic features of this rare case are discussed in light of the current literature.
Is Serum Prostate Specific Antigen Level Affected By In-And-Out Urethral Catheterization?, Yilmaz Aslan, Altuğ Tuncel, Ümi̇t Tekdoğan, Osman Özergi̇n, Ali̇ Atan
Is Serum Prostate Specific Antigen Level Affected By In-And-Out Urethral Catheterization?, Yilmaz Aslan, Altuğ Tuncel, Ümi̇t Tekdoğan, Osman Özergi̇n, Ali̇ Atan
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to investigate the effect of in-and-out urethral catheterization on serum total and free prostate specific antigen (PSA) levels and free/total PSA ratio. Materials and Methods: This is a prospective study including 24 patients who admitted with lower urinary tract symptoms and underwent in-and-out urethral catheterization with 18 F Foley catheter inserted for postvoiding residual urine measurement. Blood samples were withdrawn to determine serum total and free PSA levels and free/total PSA ratio immediately before, and at 1, 24 and 72 hours after urethral catheterization. Results: There was no alteration in total and free PSA …
An Investigation On The Natural Radioactivity Of Building Materials, Raw Materials And Interior Coatings In Central Turkey, Arman Erkan
Turkish Journal of Medical Sciences
Aim: The aim of this investigation was to measure the amount of g-decay of several building materials (brick and cement), raw materials (fly-ash and soil), interior coating materials (foam [used as a thermal insulator], water-based paints, solvent-based paints and phosphogypsum) from central Turkey, in terms of Bq kg^{-1}, and to calculate the biological damage caused by this radioactivity. Materials and Methods: Gamma-spectrometry technique has been used throughout the research in order to determine the activity of natural radionuclides. Later, annual doses were calculated. Results: The average radioactivity values were 632.2 Bq kg^{-1}for fly-ash, 4.4 Bq kg^{-1} for brick, 73.3 Bq …
Excretion Rate And Composition Of Skin Surface Lipids On The Foreheads Of Adult Males With Type Iv Hyperlipoproteinemia, Tayfun Güldür, Ni̇hayet Bayraktar, Özgür Kaynar, Gülçi̇n Beker, Muzaffer Koçer, Hamdi̇ Özcan
Excretion Rate And Composition Of Skin Surface Lipids On The Foreheads Of Adult Males With Type Iv Hyperlipoproteinemia, Tayfun Güldür, Ni̇hayet Bayraktar, Özgür Kaynar, Gülçi̇n Beker, Muzaffer Koçer, Hamdi̇ Özcan
Turkish Journal of Medical Sciences
Aim: Most of the lipids of the skin surface come from the sebaceous glands, which secrete an oily substance called sebum. Some of the sebum lipids are synthesized by sebaceous cells while some are reported to be derived from the plasma. The role of blood lipoproteins in sebum secretion rate and composition is unclear. To this end, excretion rate and composition of skin surface lipids in normo- and type IV hyperlipoproteinemic adult male subjects were compared. Materials and Methods: Quantitative analysis of skin surface lipids of subjects with type IV hyperlipoproteinemia (n:21) and normolipoproteinemia (n:15) was performed by three successive …
Spectrum Of Clinical Infectious Diseases In Hospitalized Elderly Patients In The Southeast Of Iran, Batool Sharifi-Mood, Maliheh Metanat
Spectrum Of Clinical Infectious Diseases In Hospitalized Elderly Patients In The Southeast Of Iran, Batool Sharifi-Mood, Maliheh Metanat
Turkish Journal of Medical Sciences
Aim: The elderly have defective host defenses that compromise their ability to ward off infectious agents; factors influencing immunocompetence include impaired host defenses such as diminished cell-mediated immunity, changes in chronic diseases, medications, malnutrition and functional impairments. This study was conducted in order to determine the pattern of clinical infectious diseases in a series of hospitalized elderly patients. Materials and Methods: In this cross-sectional study, all elderly patients who were admitted to our hospital in Zahedan (Southeast Iran) between 2001 and 2006 were evaluated. We retrospectively reviewed the 1278 patients for diagnostic studies, risk factors, treatment options and morbidity and …
Gastric Duplication Cyst Mimicking Pancreatic Pseudocyst/Hydatid Cyst: A Rare Presentation, Prasad Seetharam, Gabriel Rodrigues
Gastric Duplication Cyst Mimicking Pancreatic Pseudocyst/Hydatid Cyst: A Rare Presentation, Prasad Seetharam, Gabriel Rodrigues
Turkish Journal of Medical Sciences
Congenital gastrointestinal duplications are rare, and gastric duplication cysts are even rarer. Most cases are seldom diagnosed preoperatively. We present a case of gastric duplication cyst, which in preoperative imaging studies mimicked a hydatid/pseudocyst of the pancreas. The diagnosis was made only intraoperatively and was confirmed by histopathological examination of the completely excised cyst.
Case Of Tuberous Sclerosis With Pulmonary Involvement, Arzu Balkan, Cantürk Taşci, Carl R. Fuhrman
Case Of Tuberous Sclerosis With Pulmonary Involvement, Arzu Balkan, Cantürk Taşci, Carl R. Fuhrman
Turkish Journal of Medical Sciences
Tuberous sclerosis is a rare genetic disorder. The diagnosis of tuberous sclerosis requires the presence of two major or one major and two minor features. Pulmonary involvement has been reported to occur in less than 1% in patients and carries a poor prognosis. We present a female tuberous sclerosis patient with pulmonary involvement, evaluated for a positive PPD reaction.
Plasma Thrombin Activitable Fibrinolysis Inhibitor Levels In Behçet´S Disease, Mehmet Ali̇ Özcan, Servet Akar, İnci̇ Alacacioğlu, Özden Pi̇şki̇n, Fai̇ze Yüksel, Oğuz Gürler, Nurullah Akkoç, Fati̇h Demi̇rkan, Güner Hayri̇ Özsan, Şebnem Özkan, Fatoş Önen, Bülent Ündar
Plasma Thrombin Activitable Fibrinolysis Inhibitor Levels In Behçet´S Disease, Mehmet Ali̇ Özcan, Servet Akar, İnci̇ Alacacioğlu, Özden Pi̇şki̇n, Fai̇ze Yüksel, Oğuz Gürler, Nurullah Akkoç, Fati̇h Demi̇rkan, Güner Hayri̇ Özsan, Şebnem Özkan, Fatoş Önen, Bülent Ündar
Turkish Journal of Medical Sciences
Aim: The precise pathogenetic mechanisms causing thrombotic complications in Behçet´s disease (BD) are still not known. To explain the pathogenesis with coagulation induction or a defective fibrinolysis superimposed on endothelial dysfunction, various hemostatic parameters were studied. Thrombin activatable fibrinolysis inhibitor (TAFI), downregulating plasmin generation and fibrinolysis, is a novel risk factor for thrombotic disorders. We studied plasma TAFI levels in BD in comparison with healthy controls. Materials and Methods: Twenty-three patients with BD (mean age: 38.3 ± 10.83, M/F: 5/18) diagnosed according to the criteria of the International Study Group and 20 healthy volunteers (mean age: 38.05 ± 6.29, M/F: …
Effects Of Acute Fenthion Toxicity On Liver And Kidney Function And Histology In Rats, Mustafa Kerem, Nurdan Bedi̇rli̇, Nesli̇han Gürbüz, Özgür Eki̇nci̇, Abdulkadi̇r Bedi̇rli̇, Taylan Akkaya, Ömer Şakrak, Hati̇ce Paşaoğlu
Effects Of Acute Fenthion Toxicity On Liver And Kidney Function And Histology In Rats, Mustafa Kerem, Nurdan Bedi̇rli̇, Nesli̇han Gürbüz, Özgür Eki̇nci̇, Abdulkadi̇r Bedi̇rli̇, Taylan Akkaya, Ömer Şakrak, Hati̇ce Paşaoğlu
Turkish Journal of Medical Sciences
Aim: The aim of this study was to investigate the dose-related effects of fenthion on the liver and kidney and the correlation between severity of organ damage and serum butyrylcholinesterase (BChE) enzyme levels. Materials and Methods: Ninety rats were randomly subdivided into control group and 4 study groups. Control group was administered 1 ml of saline intraperitoneally. Study groups received 25, 50, 75 and 100 mg/kg of fenthion, intraperitoneally. Blood samples and renal and hepatic tissues were collected 24 h after dosing and survival was monitored for 7 days. Results: Mortality was observed in 2 rats receiving 75 mg/kg fenthion …
Is There A Correlation Between Extroversion Personality Characteristics Of Medical Students And Awareness Of Works Of Art?, Sare Alkan, Musaci̇de Zehra Ordulu, Yi̇ği̇t Sezer, Emi̇n Soyer, Di̇lek Aslan, İskender Sayek
Is There A Correlation Between Extroversion Personality Characteristics Of Medical Students And Awareness Of Works Of Art?, Sare Alkan, Musaci̇de Zehra Ordulu, Yi̇ği̇t Sezer, Emi̇n Soyer, Di̇lek Aslan, İskender Sayek
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to assess the relation between extroversion personality characteristics and awareness of works of art among a group of university students. Materials and Methods: One hundred thirty-five phase II students of the Medical Faculty of Hacettepe University registered in the 2005-2006 academic year participated in this descriptive study. In order to assess extroversion personality characteristics, Eysenck Extroversion Personality Scale was used. For determining awareness of works of art on the campus, researchers photographed selected works of arts and presented them for evaluation by the participants in a questionnaire. Four categories were determined as follows: category …
Anesthesia For An Adult Patient With Congenital Diaphragmatic Eventration, Hale Yarkan Uysal, Solmaz Günal, Ahmet Ş. Uyar, Hülya Başar
Anesthesia For An Adult Patient With Congenital Diaphragmatic Eventration, Hale Yarkan Uysal, Solmaz Günal, Ahmet Ş. Uyar, Hülya Başar
Turkish Journal of Medical Sciences
Congenital diaphragmatic eventration is an uncommon condition in adults and is defined as an abnormal elevation of the diaphragm. In adults, diaphragmatic eventration causes respiratory impairment that is associated with severe dyspnea, orthopnea and hypoxia. Most of the symptomatic patients may survive with supportive therapy without any need for surgical correction, though they are at risk of spontaneous diaphragm rupture. Spontaneous diaphragmatic rupture may develop in a patient with diaphragmatic eventration as a result of any event that leads to increase in intraabdominal pressure. In this case report, we present the anesthetic management of an adult patient with congenital diaphragmatic …
A Real-Time Transthoracic Echocardiographic Imaging Of Pulmonary Embolism In A Patient With Suspected Primary Antiphospholipid Syndrome, Hasan Kocatürk, M. Cengi̇z Çolak, Mustafa Yilmaz, Ednan Bayram, Sebahatti̇n Ateşal
A Real-Time Transthoracic Echocardiographic Imaging Of Pulmonary Embolism In A Patient With Suspected Primary Antiphospholipid Syndrome, Hasan Kocatürk, M. Cengi̇z Çolak, Mustafa Yilmaz, Ednan Bayram, Sebahatti̇n Ateşal
Turkish Journal of Medical Sciences
Clinical manifestations of antiphospholipid syndrome (APS) include repeated episodes of arterial and/or venous thrombosis, recurrent fetal wastage, and premature births. Correct diagnosis of APS requires identification of lupus anticoagulant (LA) and anticardiolipin antibodies (aCL). Other antibodies such as anti-b2 glycoprotein-I have also been detected. A 32-year-old man presented with acute left-sided hemiplegia and was admitted with a possible diagnosis of primary APS. A pulmonary embolus-in-transit was captured incidentally by transthoracic echocardiographic study.
Does Lanz® Endotracheal Tube Offer Advantage In Nitrous Oxide Anesthesia?, Özgün Cuvaş, Fatma Dokumaci, Mehmet Aki̇f Yazar, Hülya Başar
Does Lanz® Endotracheal Tube Offer Advantage In Nitrous Oxide Anesthesia?, Özgün Cuvaş, Fatma Dokumaci, Mehmet Aki̇f Yazar, Hülya Başar
Turkish Journal of Medical Sciences
Aim: Increasing intracuff pressure and postoperative laryngotracheal complications are the important issues in nitrous oxide anesthesia. The Lanz® endotracheal tube is a new kind of tube with a pressure-regulating valve. We aimed to investigate whether or not this tube may be useful in nitrous oxide anesthesia in terms of postoperative laryngotracheal complications. Materials and Methods: The study included 70 female patients, aged 18-60 years. Patients were intubated with the standard endotracheal tube in Group S (n = 35) and the Lanz® endotracheal tube in Group M (n = 35). The intracuff pressures were monitored with a manometer during general anesthesia. …
Levels Of Protein C And Protein S, Tissue-Plasminogen Activator, And Fibrinogen During Cardiopulmonary Bypass, Yahya Ünlü, Sali̇m B. Teki̇n, Hi̇kmet Koçak
Levels Of Protein C And Protein S, Tissue-Plasminogen Activator, And Fibrinogen During Cardiopulmonary Bypass, Yahya Ünlü, Sali̇m B. Teki̇n, Hi̇kmet Koçak
Turkish Journal of Medical Sciences
Aim: The exposure of blood to foreign surfaces during cardiopulmonary bypass (CPB) leads to an activation of the coagulation system. The goal of this study was to evaluate the levels of protein C and protein S, tissue-plasminogen activator (t-PA) and fibrinogen before, during and after CPB. Materials and Methods: Thirty-three patients undergoing elective coronary artery bypass grafting (CABG) and 11 patients undergoing non-cardiac surgery (control group) were included in this study. Blood samples were taken at different time intervals preoperatively, before, during and after CPB, and in the postoperative period. Protein C and protein S, t-PA and fibrinogen levels were …
The Investigation Of Nasal Mrsa Carriage And Colonization Of Nasopharyngeal Pathogens At A Primary School In Düzce, Mustafa Yildirim, İdri̇s Şahi̇n, Semra Başak, Şükrü Öksüz, Çi̇ğdem Özaydin, Selda Acar, İrfan Şencan, Oğuz Karabay
The Investigation Of Nasal Mrsa Carriage And Colonization Of Nasopharyngeal Pathogens At A Primary School In Düzce, Mustafa Yildirim, İdri̇s Şahi̇n, Semra Başak, Şükrü Öksüz, Çi̇ğdem Özaydin, Selda Acar, İrfan Şencan, Oğuz Karabay
Turkish Journal of Medical Sciences
Aim: The aim of the study was to investigate nasopharyngeal colonization of respiratory tract pathogens and nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in healthy schoolchildren (6-14 years old). Materials and Methods: The present study was conducted at Konuralp Primary School by Düzce University and 484 healthy children were included. Isolates obtained from nasal and nasopharyngeal cultures were identified by conventional microbiological procedures and Api 20 strep, NH. Results: 56.6% of healthy schoolchildren had at least one nasopharyngeal potential bacterial pathogen. Isolated bacteria species were as follows: 6% group A streptococcus (GAS), 5.0% S. pneumoniae, 33.1% M. catarrhalis, and 34.9% …
An Unusual Presentation Of Extrapulmonary Tuberculosis In An Adolescent: Isolated Unilateral Inguinal Lymphadenitis, Ekrem Güler, Selma Güler, Hasan Uçmak, Canan Eren Dağli, Mehmet Davutoğlu
An Unusual Presentation Of Extrapulmonary Tuberculosis In An Adolescent: Isolated Unilateral Inguinal Lymphadenitis, Ekrem Güler, Selma Güler, Hasan Uçmak, Canan Eren Dağli, Mehmet Davutoğlu
Turkish Journal of Medical Sciences
Isolated tuberculous inguinal lymphadenitis is a rare entity and is usually bilateral. A 16-year- old male presented with anorexia, nocturnal sweating and painless soft right inguinal lymph nodes. The patient underwent excision of lymph nodes and a Ziehl-Neelsen stain revealed the presence of acid-fast bacilli, but cultures of the lymph nodes were negative. Histological sections showed the presence of caseous necrosis and epithelioid cell granuloma. He had a positive tuberculin skin test (Mantoux) with 22 mm diameter. The patient was diagnosed as tuberculous lymphadenitis with these findings. Tuberculosis should be included in the differential diagnosis in any case of isolated …
An Impulse Control Disorder Case With Penile Fracture And Trichotillomania, Bi̇rgül Elbozan Cumurcu, Burhanetti̇n Kaya, Feryal Çam Çeli̇kel, Ahmet Soylu, Fi̇kret Erdemi̇r
An Impulse Control Disorder Case With Penile Fracture And Trichotillomania, Bi̇rgül Elbozan Cumurcu, Burhanetti̇n Kaya, Feryal Çam Çeli̇kel, Ahmet Soylu, Fi̇kret Erdemi̇r
Turkish Journal of Medical Sciences
Penile fractures are classically described as presenting with rapid detumescence of an erection associated with blunt trauma. This clinical finding is due to a tear in the tunica albuginea surrounding the corpora cavernosum. In this study, we report and discuss a case of trichotillomania and penile bending impulse resulting in penile fracture, which was operated in the urology clinic. The possible psychological and psychiatric problems underlying the impulsive behavior are discussed, and the value of a psychiatric evaluation is emphasized.
Increased Lipid Peroxidation And Decreased Antioxidant Response In Serum And Cerebrospinal Fluid In Acute Ischemic Stroke, Abdulkadi̇r Yildirim, Di̇lcan Kotan, Serap Yildirim, Recep Aygül, Fati̇h Akçay
Increased Lipid Peroxidation And Decreased Antioxidant Response In Serum And Cerebrospinal Fluid In Acute Ischemic Stroke, Abdulkadi̇r Yildirim, Di̇lcan Kotan, Serap Yildirim, Recep Aygül, Fati̇h Akçay
Turkish Journal of Medical Sciences
Background and Aim: The pathogenesis of brain damage in ischemic stroke is highly complex. The aim of the present study was to investigate the presence of oxidative stress in ischemic stroke and to determine whether the measured oxidative stress markers in serum and cerebrospinal fluid (CSF) were associated with infarction volume, and the Glasgow Coma Scale (GCS) and Glasgow Outcome Scale (GOS). Materials and Methods: The study included 32 patients with acute ischemic stroke within 48 h of onset and 18 suitable controls. Superoxide dismutase (SOD) and glutathione peroxidase (GPX) activity, glutathione (GSH) and malondialdehyde (MDA) level, and total antioxidant …
A Copper Determination Method Based On The Reaction Between 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N- Sulfopropylamino) Phenol (Nitro-Paps) And Copper For Use In Urine Copper Measurement And Application To Automation, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe
A Copper Determination Method Based On The Reaction Between 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N- Sulfopropylamino) Phenol (Nitro-Paps) And Copper For Use In Urine Copper Measurement And Application To Automation, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe
Turkish Journal of Medical Sciences
Aim: To develop a sensitive automated colorimetric urine copper determination method using a water soluble compound, 2-(5-nitro-2-pyridylazo)-5-(N-propyl-N-sulfopropylamino) phenol (nitro-PAPS), as a ligand. Materials and Methods: The new photometric method using sodium dodecyl sulfate (SDS)-ascorbic acid to dissociate copper from proteins in acetate buffer (pH 3.2) and nitro-PAPS as ligand was also adapted to an automated analyzer. Copper concentrations were determined by atomic absorption spectrophotometric method and by photometric method in 24 h urine samples of patients (n = 100) with various types of diseases including Wilson's disease (n = 12), diabetes mellitus (n = 34), osteoporosis (n = 27), nephrotic …