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Homocysteine, Vitamin B12, And Folic Acid Levels In Alzheimer's Disease, Mild Cognitive Impairment, And Healthy Elderly: Baseline Characteristics In Subjects Of The Australian Imaging Biomarker Lifestyle Study., Noel Faux, Kathryn Ellis, Lorine Porter, Chris Fowler, Simon Laws, Ralph Martins, Kelly Pertile, Alan Rembach, Chris Rowe, Rebecca Rumble, Cassandra Szoeke, Kevin Taddei, Tania Taddei, Brett Trounson, Victor Villemagne, Vanessa Ward, David Ames, Colin Masters, Ashley Bush
Homocysteine, Vitamin B12, And Folic Acid Levels In Alzheimer's Disease, Mild Cognitive Impairment, And Healthy Elderly: Baseline Characteristics In Subjects Of The Australian Imaging Biomarker Lifestyle Study., Noel Faux, Kathryn Ellis, Lorine Porter, Chris Fowler, Simon Laws, Ralph Martins, Kelly Pertile, Alan Rembach, Chris Rowe, Rebecca Rumble, Cassandra Szoeke, Kevin Taddei, Tania Taddei, Brett Trounson, Victor Villemagne, Vanessa Ward, David Ames, Colin Masters, Ashley Bush
Simon Laws
There is some debate regarding the differing levels of plasma homocysteine, vitamin B12 and serum folate between healthy controls (HC), mild cognitive impairment (MCI), and Alzheimer's disease (AD). As part of the Australian Imaging Biomarker Lifestyle (AIBL) study of aging cohort, consisting of 1,112 participants (768 HC, 133 MCI patients, and 211 AD patients), plasma homocysteine, vitamin B12, and serum and red cell folate were measured at baseline to investigate their levels, their inter-associations, and their relationships with cognition. The results of this cross-sectional study showed that homocysteine levels were increased in female AD patients compared to female HC subjects …