Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Abscess (1)
- Adult (1)
- Antitubercular Agents (1)
- Ascorbic acid (1)
- Biopsy (1)
-
- Biopsy, Fine-Needle (1)
- Department of Medical Oncology (1)
- Department of Surgery (1)
- Diagnosis (1)
- Diagnosis, Differential (1)
- Differential (1)
- Drainage (1)
- Endoscopy (1)
- Endosonography (1)
- Erlotinib (1)
- Fever (1)
- Fine-Needle (1)
- Follow-Up Studies (1)
- Gemcitabine (1)
- Humans (1)
- Intravenous (1)
- Male (1)
- Metastic cancer (1)
- Mycobacterium tuberculosis (1)
- Myrna Brind Center of Integrative Medicine (1)
- Pancreatic Pseudocyst (1)
- Pancreatic cancer (1)
- Pancreatitis (1)
- Phase I study (1)
- Risk Assessment (1)
- File Type
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Tubercular Pancreatic Abscess Presenting As Fever And Cystic Pancreatic Lesion With Endoscopic Management., Jonathan Fenkel, Maya Spodik, Bheema Singu, Anthony Infantolino, Sandeep Deshmukh, David Loren
Tubercular Pancreatic Abscess Presenting As Fever And Cystic Pancreatic Lesion With Endoscopic Management., Jonathan Fenkel, Maya Spodik, Bheema Singu, Anthony Infantolino, Sandeep Deshmukh, David Loren
Sandeep Deshmukh
Isolated pancreatic tuberculosis is a rare presentation of tubercular infection. There are few reported cases of pancreatic tuberculosis diagnosed by endoscopic ultrasound with fine-needle aspiration (EUS FNA), though EUS is often used in the evaluation of pancreatic cystic lesions. We present a case of a tubercular pancreatic abscess presenting as a cystic lesion in a patient with undiagnosed immunodeficiency. The abscess was aspirated by EUS FNA and treated with endoscopic drainage and anti-mycobacterial medications.
Phase I Evaluation Of Intravenous Ascorbic Acid In Combination With Gemcitabine And Erlotinib In Patients With Metastatic Pancreatic Cancer., Daniel A. Monti, Md, Edith Mitchell, Anthony J Bazzan, Susan Littman, George Zabrecky, Charles J Yeo, Madhaven V Pillai, Andrew B Newberg, Sandeep Deshmukh, Mark Levine
Phase I Evaluation Of Intravenous Ascorbic Acid In Combination With Gemcitabine And Erlotinib In Patients With Metastatic Pancreatic Cancer., Daniel A. Monti, Md, Edith Mitchell, Anthony J Bazzan, Susan Littman, George Zabrecky, Charles J Yeo, Madhaven V Pillai, Andrew B Newberg, Sandeep Deshmukh, Mark Levine
Sandeep Deshmukh
BACKGROUND: Preclinical data support further investigation of ascorbic acid in pancreatic cancer. There are currently insufficient safety data in human subjects, particularly when ascorbic acid is combined with chemotherapy. METHODS AND FINDINGS: 14 subjects with metastatic stage IV pancreatic cancer were recruited to receive an eight week cycle of intravenous ascorbic acid (three infusions per week), using a dose escalation design, along with standard treatment of gemcitabine and erlotinib. Of 14 recruited subjects enrolled, nine completed the study (three in each dosage tier). There were fifteen non-serious adverse events and eight serious adverse events, all likely related to progression of …