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Rehabilitation Practice and Science
Axonal degeneration;diabetes mellitus;neuropathy;single fiber electromyography
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Axonal Degeneration In Diabetic Neuropathy: An Assessment Of Single Fiber Electromyography, Chein-Wei Chang, Lee-Ming Chuang, I-Nan Lien
Axonal Degeneration In Diabetic Neuropathy: An Assessment Of Single Fiber Electromyography, Chein-Wei Chang, Lee-Ming Chuang, I-Nan Lien
Rehabilitation Practice and Science
Peripheral neuropathy is an important complication of diabetes mellitus. However, neuropathological changes in diabetic neuropathy with axonal degeneration or segmental demyelination are still unclear. By using a newly developing electrodiagnostic method of single fiber electromyography (SFEMG) with a computer-aided program, mean jitter value and muscle fiber density were measured in extensor digitorum communis (EDC) and anterior tibial (AT) muscles from 36 diabetic patients with neuropathy (group 1) and 12 patients without neuropathy (group Ⅱ) proved by nerve conduction study. The results showed an increased mean jitter value, fiber density and abnormal percentage both in EDC and AT muscles in group …