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Is High Dose Intramuscular Alefacept A More Effective And Safe Treatment Option In Visibly Reducing The Severity Of Chronic Plaque Psoriasis In Men And Women 16 Years And Older Compared To Standard Iv And Im Treatment Forms?, Andrew Foster
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not high dose intramuscular alefacept is a more effective and a safe treatment option in visibly reducing the severity of chronic plaque psoriasis in men and women 16 years and older compared to standard IV and IM treatment forms.
Study Design: Review of three dichotomous data, English language, and primary randomized controlled trials published 2003 – 2008.
Data Sources: Randomized, controlled clinical trials comparing alefacept to a control
group were found using PubMed database.
Outcome Measured: Disease improvement and the adverse effect of headache. Disease
improvement was …