Medicine and Health Sciences Commons^™

In Vivo Measurement Of Color Relationships Between The Maxillary Central Incisor And Canine As A Function Of Age, Marie E. Falcone

Master's Theses

Abstract

Introduction

It has long been taught that the basic shade (hue) of the patient can be taken from the canine (i.e. that tooth thought to have the highest chroma of a particular hue) and then that hue can be applied to other anterior teeth but at a lower chroma. However, this concept does not appear to derive from published measurements or observations. This study documented the color relationship between in vivo maxillary central incisors and canines to examine: (1) whether they share the same hue, but have different chromas (as commonly taught); and, (2) whether color differences (∆E values) …

Ischemia Impairs Vasodilation In Skeletal Muscle Resistance Artery, Kyle Remington Struthers

Master's Theses

Functional vasodilation in arterioles is impaired with chronic ischemia. We sought to examine the impact of chronic ischemia and age on skeletal muscle resistance artery function. To examine the impact of chronic ischemia, the femoral artery was resected from young (2-3mo) and adult (6-7mo) mice and the profunda femoris artery diameter was measured at rest and following gracilis muscle contraction 14 days later using intravital microscopy. Functional vasodilation was significantly impaired in ischemic mice (14.4±4.6% vs. 137.8±14.3%, p<0.0001 n=8) and non-ischemic adult mice (103.0±9.4% vs. 137.8±14.3%, p=0.05 n=10). In order to analyze the cellular mechanisms of the impairment, a protocol was developed to apply pharmacological agents to the experimental preparation while maintaining tissue homeostasis. Endothelial and smooth muscle dependent vasodilation were impaired with ischemia, 39.6 ± 13.6% vs. 80.5 ± 11.4% and 43.0 ± 11.7% vs. 85.1 ± 10.5%, respectively. From this data, it can be supported that smooth muscle dysfunction is the reason for the observed impairment in arterial vasodilation.