Medicine and Health Sciences Commons^™

A Comparison Of Three Bicycle Pedal Types And Power Output, Brandon Kuhn

Master's Theses

The purpose of this study was to examine the power output over a 30-second maximum effort bicycle sprint with three different pedal types; clipless, toe-strap, and flat. The participants for this investigation were eight (7 males and 1 female) mountain bikers with ages between 20 and 55 ( Age = 40) from the Central Kansas Mountain Bike Club. Each participant was required to provide his or her own bicycle and the researchers provided the training stand, Saris CycleOps PowerTap rear wheel, and Garmin Edge 500 cycling computer used for data collection. Testing procedure consisted of a warmup, 30- second maximal …

Resveratrol + Ethanol Preconditioning And Neuroprotection, Nastaran Khodaie

Master's Theses

Our lab established that moderate ethanol preconditioning (MEP) for 6 days blocked the Aâ25-35 toxicity in cerebellar mixed cell cultures and It has been shown that MEP cause the up regulation of the pre-survival enzymes such as proxiredoxin2 (PRX2), which suggests MEP can activate the cell survival pathways against upcoming toxins.

This study was performed to verify the possible combinatory effect of ethanol and resveratrol against Aâ25-35 toxicity. Both ethanol and resveratrol sub-protective concentrations were detected against Aâ25-35 in cerebellar mixed cell cultures. The combination of sub-protective levels of ethanol and resveratrol showed the significantly reduction in number of Aâ25-35 …

The Impact Of Algal Community Succession, Taxonomic Composition And Biomass Accrual, On Denitrification Potential Of Stream Periphyton, Allison Daley

Master's Theses

We investigated the relationship between algal taxonomy, community succession and biomass accrual and denitrification potential (DNP) within stream periphyton. Field research was conducted in 6 DuPage County, II forest preserve streams with diverse physical and chemical characteristics and in an experiment in the artificial stream facility at Loyola University Chicago in which 2 sets of streams were amended with nutrients and compared to an unamended set of streams. Algal communities in the field study streams were sampled over 12 weeks late spring/summer and NMDS ordination plots identified 4 distinct communities. Correlations with algal community NMDS axis scores and the relative …

Determination Of The Molecular Mechanisms Of Hyperglycemia-Induced Changes In Cav3.2 Calcium Channel Properties, Ginny Marie Keeling

Master's Theses

Hyperglycemia can cause altered excitability due to increased CaV3.2 T-type calcium channel function, bestowing diabetics an increased neuropathy risk. The objective of this study was to understand the molecular mechanisms of increased CaV3.2 function during hyperglycemia in vitro, which leads to a 58% increase in current density and increased channel open probability (PO), among other changes. Two major findings are reported in this study:

1) The enzymatic elimination of extracellular N-acetylneuraminic acid (NANA) moieties reversed the increase in current density and the shift in PO, showing that hyper-glycosylation alters channel function in disease.

2) Treatment with GM1 (a ganglioside highly …