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MCV/Q, Medical College of Virginia Quarterly

Stoneburner Lecture Series

Publication Year

Articles 1 - 30 of 42

Full-Text Articles in Medicine and Health Sciences

Arteriography Of Cerebrovascular Disease, Frederick S. Vines Jan 1974

Arteriography Of Cerebrovascular Disease, Frederick S. Vines

MCV/Q, Medical College of Virginia Quarterly

The importance of complete angiographic studies in patients suspected of extracranial vascular disease has been emphasized. Examples of a variety of lesions of the intracranial and extracranial circulation have been shown. It is important that the angiographer obtain adequate visualization of the circulation cephalad to the aortic arch with awareness of the type of lesion and technical problems that may be encountered. It is only in this way that further understanding of the "stroke syndrome" can be attained with appropriate therapy.


The Neuro-Ophthalmology Of Cerebrovascular Disease, John W. Harbison Jan 1974

The Neuro-Ophthalmology Of Cerebrovascular Disease, John W. Harbison

MCV/Q, Medical College of Virginia Quarterly

The neuro-ophthalmology of cerebrovascular disease is a vast plain of neuro-ophthalmic vistas, encompassing virtually all areas of disturbances of the eye-brain mechanism. This paper will be restricted to those areas of the neuro-ophthalmology of cerebrovascular disease which one might consider advances in its clinical diagnosis and treatment.


Medical Management Of Cerebral Vascular Disease, William K. Hass Jan 1974

Medical Management Of Cerebral Vascular Disease, William K. Hass

MCV/Q, Medical College of Virginia Quarterly

The judicious mixture of surgical therapy and prophylactic therapy with a safe platelet antiaggregant appears at this time to be the best combination of approaches to the axiom: The best time to treat a stroke is before it happens.


Advances In The Surgical Treatment Of Patients With Extracranial Cerebral Vascular Disease, Thoralf M. Sundt Jr. Jan 1974

Advances In The Surgical Treatment Of Patients With Extracranial Cerebral Vascular Disease, Thoralf M. Sundt Jr.

MCV/Q, Medical College of Virginia Quarterly

Since the subject of surgery for carotid artery occlusive disease is too broad to be covered in its entirety, we will dwell primarily on some results of cerebral blood flow measurements and electroencephalograms performed during this procedure, their meaning and relationship to states of cerebral ischemia, and some controversial aspects of the surgery. An understanding of cerebral hemodynamics and the tolerance of neural tissue to ischemia is of major importance to any surgeon or physician dealing with this illness.


Clinical Advances In The Evaluation Of Deep Coma, Cary Suter Jan 1974

Clinical Advances In The Evaluation Of Deep Coma, Cary Suter

MCV/Q, Medical College of Virginia Quarterly

Today, 1974, in large medical centers, evaluation of the patient in coma is almost a daily necessity, and the need to evaluate the patient in deep coma arises once or twice every week. Even in smaller hospitals the problem is not uncommon. This has come about because many laymen and most medical personnel are now well trained in methods of cardiorespiratory resuscitation. Persons are not allowed to die easily and once resuscitated, are moved to intensive care units where life is maintained. Fortunately, if they do not die of their underlying disease, such as trauma or myocardial infarction, many patients …


Introduction, Donald P. Becker Jan 1974

Introduction, Donald P. Becker

MCV/Q, Medical College of Virginia Quarterly

This issue represents the second part of the 27th Annual Stoneburner Lecture Series delivered at the Medical College of Virginia in February 1974. Here, we are dealing with clinical applications of recent advances in our understanding of brain mechanisms and brain disease processes.


Clinical Advances In The Management Of Patients With Sever Head Injury, Thomas W. Langfitt Jan 1974

Clinical Advances In The Management Of Patients With Sever Head Injury, Thomas W. Langfitt

MCV/Q, Medical College of Virginia Quarterly

Some of the physiological properties of the cerebral circulation, intracranial pressure and brain metabolism, as well as some of the pathophysiological alterations that we see with various types of brain injuries have been discussed in this series. We are going to see how we can apply some of this information clinically.


Continuous Intracranial Pressure Monitoring In Patients With Brain Injury: Technique And Application, John K. Vries Jan 1974

Continuous Intracranial Pressure Monitoring In Patients With Brain Injury: Technique And Application, John K. Vries

MCV/Q, Medical College of Virginia Quarterly

Continuous ICP monitoring using the hollow screw technique has proven itself simple, safe, and reliable. The obvious advantage of continuous ICP monitoring is to provide early warning of developing mass lesions before clinical signs appear and to assess the effectiveness of therapy directed at brain edema. Its most important use, however, may be that it permits the use of depressant medications in these patients. Many of these patients have a marked tendency toward hyperthermia, severe hyperventilation, and erratic blood pressure swings. These tendencies can be most difficult to control with conventional treatment regimens. By sedating these patients, however, it is …


Practical Anticonvulasant Pharmacokinetics, R.B. David, L.K. Garrettson Jan 1974

Practical Anticonvulasant Pharmacokinetics, R.B. David, L.K. Garrettson

MCV/Q, Medical College of Virginia Quarterly

Pharmacokinetics is that area of pharmacology concerned with the absorption, distribution, metabolism, and elimination of drugs. The processes by which absorption, distribution, and elimination take place are referred to as unit processes. These occur independently and concurrently, and involve such activities as absorption into the blood, elimination from the blood, distribution between the blood and tissue, inactivation in tissues, and finally, elimination from the blood. Drug handling by the body can be characterized by the rate for each step or, more often, the rate of all processes. Classification of observed kinetics for these rate processes includes first-order, zero-order, and capacity-limited …


Radical Reconstruction Of Complex Cranio-Orbito-Facial Abnormalities, John A. Jane, Milton T. Edgerton Jan 1974

Radical Reconstruction Of Complex Cranio-Orbito-Facial Abnormalities, John A. Jane, Milton T. Edgerton

MCV/Q, Medical College of Virginia Quarterly

Excellent cosmetic results can be obtained by early intervention in severe cranial-orbital-facial deformity. This intervention should take the form of a combined intracranial and extracranial approach. While the procedure is of great magnitude, the benefits to the patient and to the family seem worth the risk.


Author Index, Volume Ten, 1974. Jan 1974

Author Index, Volume Ten, 1974.

MCV/Q, Medical College of Virginia Quarterly

Author index for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten.


Introduction, Donald P. Becker Jan 1974

Introduction, Donald P. Becker

MCV/Q, Medical College of Virginia Quarterly

Recently, important strides have been made in clinical neurology and clinical neurosurgery, culminating in improved patient care. The last ten years have witnessed a new sophistication in neuroradiology, and the clear development of neuroophthalmology as a subspecialty. It is to these areas that the speakers at the 27th Stoneburner Lecture Series addressed themselves. The first part of the program emphasized cerebral vascular disease, and is presented in this issue. The second part of the program related primarily to the clinical care of patients with mechanical brain injury, brain tumors, and seizures, and will be presented in the following issue of …


The Interrelationship Of Intracranial Pressure, Cerebral Blood Flow, And Brain Metabolism In Experimental Brain Injury, Thomas W. Langfitt Jan 1974

The Interrelationship Of Intracranial Pressure, Cerebral Blood Flow, And Brain Metabolism In Experimental Brain Injury, Thomas W. Langfitt

MCV/Q, Medical College of Virginia Quarterly

This presentation will be concerned with some of the relationships between intracranial pressure, cerebral blood flow, and brain metabolism as defined in animal models. We will also be concerned with the pathophysiological changes that occur among these numerous variables.


Chromosome Abnormalities And Repeated Abortion: A Preliminary Report, Susan English, Deborah W. Heritage, Andrew T. L. Chen, Reuben B. Young Jan 1974

Chromosome Abnormalities And Repeated Abortion: A Preliminary Report, Susan English, Deborah W. Heritage, Andrew T. L. Chen, Reuben B. Young

MCV/Q, Medical College of Virginia Quarterly

In view of the increased frequency of chromosome rearrangements demonstrated in these couples and the importance of counseling for future pregnancies, it would be wise to consider cytogenetic evaluation when all other probable causes for recurrent abortion have been ruled out.


Reconstructive Intracranial Vascular Surgery, John M. Tew Jr. Jan 1974

Reconstructive Intracranial Vascular Surgery, John M. Tew Jr.

MCV/Q, Medical College of Virginia Quarterly

It is scarcely less than two decades since the initial cautious explorations of reconstructive surgery for the prevention of cerebral infarction caused by extracranial vascular disease began. The next years recorded an accumulative experience in the field of vascular surgery. Early clinical investigations led to the discovery that extracranial vascular disease is a major cause of cerebral infarction or stroke. Estimates indicate, however, that only 30-40% of the patients with cerebrovascular insufficiency have significant extracranial occlusive disease. For this larger group of patients, previous surgical methods offer no hope. It is the purpose of this report to review the current …


Advances In The Management Of Pituitary Tumors, Charles B. Wilson Jan 1974

Advances In The Management Of Pituitary Tumors, Charles B. Wilson

MCV/Q, Medical College of Virginia Quarterly

A new development in the management of pituitary tumors is the transsphenoidal technique. It will be my purpose to show that it provides an elegant way of handling the great majority of pituitary problems, at least the ones that I have encountered, although it has its shortcomings as well as its advantages.


Advances In The Medical And Surgical Management Of Intractable Partial Complex Seizures, Hooshang Hooshmand Jan 1974

Advances In The Medical And Surgical Management Of Intractable Partial Complex Seizures, Hooshang Hooshmand

MCV/Q, Medical College of Virginia Quarterly

Seizures can be due to a variety of acute, subacute, or chronic diseases with different etiologies. Clinically, they may manifest as focal or generalized phenomena. Whereas the majority of the patients suffering from partial seizures are easily controlled with medications, in a small number of patients treatment may fail. The failure may be due to incorrect diagnosis or incorrect therapy. The efficacy of medical treatment for seizure disorder depends upon six factors: 1) dosage; 2) the size of the patient; 3) drug interaction; 4) drug specificity for the disease; 5) the nature of the disease for which the drug is …


Advances In The Treatment Of Patients With Benign Brain Tumors, Harold F. Young Jan 1974

Advances In The Treatment Of Patients With Benign Brain Tumors, Harold F. Young

MCV/Q, Medical College of Virginia Quarterly

Reliable ICP measurement allows an exact quantitation and management of intracranial pressure. This precise assessment of ICP is a valuable adjunct in the management of anesthesia for brain tumor patients. The proper combination of ICP and anesthesia management enables the surgeon to use the operating microscope to approach previously inaccessible areas of the brain and to perform meticulous surgery with a better prognosis for the brain tumor patient.


Progress And Problems In The Rehabilitation Of Patients With Central Nervous System Injuries, L.D. Amick Jan 1974

Progress And Problems In The Rehabilitation Of Patients With Central Nervous System Injuries, L.D. Amick

MCV/Q, Medical College of Virginia Quarterly

Let us briefly consider the general nature of contemporary rehabilitation with highlights of its progress and problems. Paraplegia and hemiparesis may be thought of as the models of neurologic impairment.


Table Of Contents, Volume Ten, 1974. Jan 1974

Table Of Contents, Volume Ten, 1974.

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten.


Neuro-Ophthalmology In Severe Head Injury, John W. Harbison Jan 1974

Neuro-Ophthalmology In Severe Head Injury, John W. Harbison

MCV/Q, Medical College of Virginia Quarterly

If asked what the significance of neuro-ophthalmology is in the evaluation of severe head injury, many medical and surgical practitioners of neurology would promptly reply that it consists of monitoring pupillary reactivity in anticipation of the uncal herniation syndrome. A discussion of two broad premises of a factual nature, however, should easily convince these same practitioners that the neuro-ophthalmic evaluation of patients with severe head injuries offers far more than the Hutchinson pupil.


Advances In Neuroradiology, Frederick S. Vines, Charles Bonstelle Jan 1974

Advances In Neuroradiology, Frederick S. Vines, Charles Bonstelle

MCV/Q, Medical College of Virginia Quarterly

The development of two new radiological techniques has significantly enhanced the performance of neuroradiological diagnostic procedures. The first of these was installed as the prototype unit at the Medical College of Virginia in November of 1972 and has marked advantages for the performance of encephalography, angiography, and air myelography. The present communication will relate the experiences of the author during the initial 15 months of clinical evaluation. The second technique is an entirely new concept of obtaining further information from the data provided by the penetration of x-ray photons. Each of these units will be discussed briefly with an outline …


Advances In The Management And Surgical Treatment Of Intracranial Aneurysms, Thoralf M. Sundt Jr. Jan 1974

Advances In The Management And Surgical Treatment Of Intracranial Aneurysms, Thoralf M. Sundt Jr.

MCV/Q, Medical College of Virginia Quarterly

Patients who have sustained a spontaneous subarachnoid hemorrhage are victims of a very serious illness. Not only are they subject at all times to the potentially catastrophic results of a recurrent bleed, but they are faced with the manifestations of the irritative effects of blood in the subarachnoid space where the blood may function as a poison to the vessel wall. These acutely ill individuals may suffer a composite of secondary effects from a bleed which may include a communicating hydrocephalus, cerebral edema (ischemic or chemically induced), sterile meningitis, inappropriate ADH syndrome (osmotic effects of blood in the cerebrospinal fluid), …


Advances In The Management Fo Patients With Malignant Brain Tumors, Charles B. Wilson Jan 1974

Advances In The Management Fo Patients With Malignant Brain Tumors, Charles B. Wilson

MCV/Q, Medical College of Virginia Quarterly

In describing what is new in the management of malignant brain tumors, I shall confine myself largely to chemotherapy and shall outline what we think is important based on our own experience, what we have achieved with single and multiple agents, and where we are going. We have just reviewed our five-year experience and find that chemotherapy, perhaps, is the only thing that is new.


Cerebral Blood Flow Studies In Stroke, John Stirling Meyer Jan 1974

Cerebral Blood Flow Studies In Stroke, John Stirling Meyer

MCV/Q, Medical College of Virginia Quarterly

This consideration of the relationship of neuro-transmitters not only to cerebral infarction but also to subarachnoid hemorrhage is, to my mind, the most promising area of investigation over the next decade. There is also a quantity of evidence that neurotransmitters play a large part in spasm following subarachnoid hemorrhage and in the disturbance of neurological function in that situation. Following subarachnoid hemorrhage, some remediable medical problems arise. Apart from clipping of the aneurysm, which the neurosurgeons are able to do, there is the problem of communicating hydrocephalus, which is extremely common in about 40% of patients. It can be discerned …


Clinical Advances In The Diagnosis Of Cerebral Vascular Disease, John Stirling Meyer Jan 1974

Clinical Advances In The Diagnosis Of Cerebral Vascular Disease, John Stirling Meyer

MCV/Q, Medical College of Virginia Quarterly

I have chosen some thoughts about recent clinical advances in the diagnosis of cerebral vascular disease, which I feel are appropriate for this paper, confining my discussion to the signs, symptoms, natural history, and risk factors of cerebral vascular disease.


Contents Jan 1973

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1973, Volume Nine, Number Three.


Psychiatric Problems In Urology, James L. Mathis Jan 1973

Psychiatric Problems In Urology, James L. Mathis

MCV/Q, Medical College of Virginia Quarterly

In summary, the urologist cannot escape from a major responsibility for his patients' emotional components. The very area of his work is highly charged with emotional potential, primarily of a sexual nature. A careful sexual history is essential to the full understanding of the symptoms of many urological complaints and is equally necessary for the prevention of emotional complications to genital surgery.


The Urologist And The Law, Jack B. Russell Jan 1973

The Urologist And The Law, Jack B. Russell

MCV/Q, Medical College of Virginia Quarterly

Some of the matters I have referred to may seem unusual or unlikely and thus may not be long remembered. Let me reiterate, however, the importance of two items in particular. If nothing else remains long in your minds, do not forget that complete and adequate records are essential, both in the hospital and in the office. Nothing else will take their place when they are needed. Finally, keep in mind always the significance of informed consent. It is a rapidly changing principle and one which touches literally every field of medicine. It may be difficult to accept in all …


Renal Hypertension, Eugene F. Poutasse Jan 1973

Renal Hypertension, Eugene F. Poutasse

MCV/Q, Medical College of Virginia Quarterly

The advances in our knowledge of renal hypertension over the last 75 years represents outstanding accomplishments in experimental and clinical medicine. A review of the highlights of this important investigation in hypertension should begin with Tigerstedt and Bergman's work in Scandinavia which demonstrated in 1898, that extracts of kidney possessed a hypertensive action. They gave the name "renin" to the impure substance which produced this effect. For the next 30 years much work was done on the vasoconstrictor action of extracts of the adrenal medulla, the nervous system and the kidney.