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Full-Text Articles in Medicine and Health Sciences

Impact Of Cardiopulmonary Resuscitation On Survival In Cancer Patients: Do Not Resuscitate Before Or After Cpr?, Dana E Giza, Jordan Graham, Teodora Donisan, Dinu V Balanescu, John Crommet, Gregory Botz, Cristina Gutierrez, Mariberta Vidal, Rodrigo Mejia, Cezar Iliescu Jun 2020

Impact Of Cardiopulmonary Resuscitation On Survival In Cancer Patients: Do Not Resuscitate Before Or After Cpr?, Dana E Giza, Jordan Graham, Teodora Donisan, Dinu V Balanescu, John Crommet, Gregory Botz, Cristina Gutierrez, Mariberta Vidal, Rodrigo Mejia, Cezar Iliescu

Journal Articles

No abstract provided.


Dietary Fat And Sugar Differentially Affect Β-Adrenergic Stimulation Of Cardiac Erk And Akt Pathways In C57bl/6 Male Mice Subjected To High-Calorie Feeding, Sadia Ashraf, Gizem Yilmaz, Xu Chen, Romain Harmancey May 2020

Dietary Fat And Sugar Differentially Affect Β-Adrenergic Stimulation Of Cardiac Erk And Akt Pathways In C57bl/6 Male Mice Subjected To High-Calorie Feeding, Sadia Ashraf, Gizem Yilmaz, Xu Chen, Romain Harmancey

Journal Articles

BACKGROUND: High dietary fat and sugar promote cardiac hypertrophy independently from an increase in blood pressure. The respective contribution that each macronutrient exerts on cardiac growth signaling pathways remains unclear.

OBJECTIVE: The goal of this study was to investigate the mechanisms by which high amounts of dietary fat and sugar affect cardiac growth regulatory pathways.

METHODS: Male C57BL/6 mice (9 wk old; n = 20/group) were fed a standard rodent diet (STD; kcal% protein-fat-carbohydrate, 29-17-54), a high-fat diet (HFD; 20-60-20), a high-fat and high-sugar Western diet (WD; 20-45-35), a high-sugar diet with mixed carbohydrates (HCD; 20-10-70), or a high-sucrose diet …


Reduction In St-Segment Elevation Cardiac Catheterization Laboratory Activations In The United States During Covid-19 Pandemic, S Garcia, Ms Albaghdadi, Pm Meraj, C Schmidt, R Garberich, Fa Jaffer, S Dixon, Jj Rade, M Tannenbaum, Td Henry, +2 Additional Authors Jan 2020

Reduction In St-Segment Elevation Cardiac Catheterization Laboratory Activations In The United States During Covid-19 Pandemic, S Garcia, Ms Albaghdadi, Pm Meraj, C Schmidt, R Garberich, Fa Jaffer, S Dixon, Jj Rade, M Tannenbaum, Td Henry, +2 Additional Authors

Journal Articles

No abstract provided.


Management Of Elective Aortic Valve Replacement Over The Long Term In The Era Of Covid-19, C Basman, Ca Kliger, L Pirelli, Sj Scheinerman Jan 2020

Management Of Elective Aortic Valve Replacement Over The Long Term In The Era Of Covid-19, C Basman, Ca Kliger, L Pirelli, Sj Scheinerman

Journal Articles

No abstract provided.


Covid-19 Leading To Acute Encephalopathy In A Patient With Heart Transplant., K Jang, A Khatri, Dt Majure Jan 2020

Covid-19 Leading To Acute Encephalopathy In A Patient With Heart Transplant., K Jang, A Khatri, Dt Majure

Journal Articles

No abstract provided.


Guidance For Rebooting Electrophysiology Through The Covid-19 Pandemic From The Heart Rhythm Society And The American Heart Association Electrocardiography And Arrhythmias Committee Of The Council On Clinical Cardiology., Dr Lakkireddy, Mk Chung, Tf Deering, R Gopinathannair, Cm Albert, Lm Epstein, Cv Harding, Jl Hurwitz, Cc Jeffery, Mj Shah, +9 Additional Authors Jan 2020

Guidance For Rebooting Electrophysiology Through The Covid-19 Pandemic From The Heart Rhythm Society And The American Heart Association Electrocardiography And Arrhythmias Committee Of The Council On Clinical Cardiology., Dr Lakkireddy, Mk Chung, Tf Deering, R Gopinathannair, Cm Albert, Lm Epstein, Cv Harding, Jl Hurwitz, Cc Jeffery, Mj Shah, +9 Additional Authors

Journal Articles

No abstract provided.


Effect Of Chloroquine, Hydroxychloroquine, And Azithromycin On The Corrected Qt Interval In Patients With Sars-Cov-2 Infection, M Saleh, J Gabriels, D Chang, Bs Kim, A Mansoor, E Mahmood, P Makker, H Ismail, B Goldner, J Willner, S Beldner, R Mitra, R John, J Chinitz, N Skipitaris, S Mountantonakis, Lm Epstein Jan 2020

Effect Of Chloroquine, Hydroxychloroquine, And Azithromycin On The Corrected Qt Interval In Patients With Sars-Cov-2 Infection, M Saleh, J Gabriels, D Chang, Bs Kim, A Mansoor, E Mahmood, P Makker, H Ismail, B Goldner, J Willner, S Beldner, R Mitra, R John, J Chinitz, N Skipitaris, S Mountantonakis, Lm Epstein

Journal Articles

No abstract provided.


Covid-19 In Recent Heart Transplant Recipients: Clinicopathologic Features And Early Outcomes, B. Lima, G. Gibson, S Vullaganti, K. Malhame, S Maybaum, St Hussain, S Shah, Dt Majure, F Wallach, K Jang, V Bijol, Mj Esposito, Ak Williamson, Rm Thomas, Ta Bhuiya, Ha Fernandez, Gr Stevens Jan 2020

Covid-19 In Recent Heart Transplant Recipients: Clinicopathologic Features And Early Outcomes, B. Lima, G. Gibson, S Vullaganti, K. Malhame, S Maybaum, St Hussain, S Shah, Dt Majure, F Wallach, K Jang, V Bijol, Mj Esposito, Ak Williamson, Rm Thomas, Ta Bhuiya, Ha Fernandez, Gr Stevens

Journal Articles

No abstract provided.


Hypermetabolism And Coronavirus Disease 2019, Pj Yu, H Cassiere, S Derosa, K Bocchieri, S Yar, A Hartman Jan 2020

Hypermetabolism And Coronavirus Disease 2019, Pj Yu, H Cassiere, S Derosa, K Bocchieri, S Yar, A Hartman

Journal Articles

No abstract provided.


Incidence Of Arrhythmias And Electrocardiographic Abnormalities In Symptomatic Pediatric Patients With Pcr-Positive Sars-Cov-2 Infection, Including Drug-Induced Changes In The Corrected Qt Interval, S Samuel, Ra Friedman, C Sharma, M Ganigara, E Mitchell, C Schleien, Ad Blaufox Jan 2020

Incidence Of Arrhythmias And Electrocardiographic Abnormalities In Symptomatic Pediatric Patients With Pcr-Positive Sars-Cov-2 Infection, Including Drug-Induced Changes In The Corrected Qt Interval, S Samuel, Ra Friedman, C Sharma, M Ganigara, E Mitchell, C Schleien, Ad Blaufox

Journal Articles

No abstract provided.


Management Of Acute Myocardial Infarction During The Covid-19 Pandemic., E Mahmud, Hl Dauerman, Fg Welt, Jc Messenger, Sv Rao, C Grines, A Mattu, R Jauhar, P Meraj, Td Henry, +3 Additional Authors Jan 2020

Management Of Acute Myocardial Infarction During The Covid-19 Pandemic., E Mahmud, Hl Dauerman, Fg Welt, Jc Messenger, Sv Rao, C Grines, A Mattu, R Jauhar, P Meraj, Td Henry, +3 Additional Authors

Journal Articles

No abstract provided.


Life Interrupted: On The Front Lines With Covid-19, E Argulian, Jw Weinsaft, Rc Hendel, Vp Garg, J Kim, Lm Phillips, J H. Mieres, A Abidov, R Blankstein, J Narula, +1 Additional Author Jan 2020

Life Interrupted: On The Front Lines With Covid-19, E Argulian, Jw Weinsaft, Rc Hendel, Vp Garg, J Kim, Lm Phillips, J H. Mieres, A Abidov, R Blankstein, J Narula, +1 Additional Author

Journal Articles

No abstract provided.


North American Covid-19 St-Segment-Elevation Myocardial Infarction (Nacmi) Registry: Rationale, Design, And Implications: Rationale And Design Of Nacmi Registry, P Dehghani, Lj Davidson, Cl Grines, K Nayak, J Saw, P Kaul, A Bagai, R Garberich, P Meraj, Td Henry, +9 Additional Authors Jan 2020

North American Covid-19 St-Segment-Elevation Myocardial Infarction (Nacmi) Registry: Rationale, Design, And Implications: Rationale And Design Of Nacmi Registry, P Dehghani, Lj Davidson, Cl Grines, K Nayak, J Saw, P Kaul, A Bagai, R Garberich, P Meraj, Td Henry, +9 Additional Authors

Journal Articles

No abstract provided.


Spontaneous Coronavirus Disease 2019 (Covid-19)-Associated Luminal Aortic Thrombus, C Mullan, C Powierza, Pe Miller, A Geirsson, P Vallabhajosyula, R Assi Jan 2020

Spontaneous Coronavirus Disease 2019 (Covid-19)-Associated Luminal Aortic Thrombus, C Mullan, C Powierza, Pe Miller, A Geirsson, P Vallabhajosyula, R Assi

Journal Articles

No abstract provided.


Aortic Arch Thrombus And Pulmonary Embolism In A Covid-19 Patient, P. Gandotra, A. Supariwala, S. Selim, G. Garra, L. Gruberg Jan 2020

Aortic Arch Thrombus And Pulmonary Embolism In A Covid-19 Patient, P. Gandotra, A. Supariwala, S. Selim, G. Garra, L. Gruberg

Journal Articles

© 2020 Elsevier Inc. Background: Coronavirus disease 2019 (COVID-19) is associated with endothelial inflammation and a hypercoagulable state resulting in both venous and arterial thromboembolic complications. We present a case of COVID-19-associated aortic thrombus in an otherwise healthy patient. Case Report: A 53-year-old woman with no past medical history presented with a 10-day history of dyspnea, fever, and cough. Her pulse oximetry on room air was 84%. She tested positive for severe acute respiratory syndrome coronavirus 2 infection, and chest radiography revealed moderate patchy bilateral airspace opacities. Serology markers for cytokine storm were significantly elevated, with a serum D-dimer level …


Bradyarrhythmias In Patients With Covid-19: Marker Of Poor Prognosis?, J. S. Chinitz, R. Goyal, M. Harding, G. Veseli, L. Gruberg, R. Jadonath, P. Maccaro, P. Gandotra, L. Ong, L. M. Epstein Jan 2020

Bradyarrhythmias In Patients With Covid-19: Marker Of Poor Prognosis?, J. S. Chinitz, R. Goyal, M. Harding, G. Veseli, L. Gruberg, R. Jadonath, P. Maccaro, P. Gandotra, L. Ong, L. M. Epstein

Journal Articles

No abstract provided.


Cardiac Catheterization Laboratory Volume Changes During Covid-19—Findings From A Cardiovascular Fellows Consortium, S. Kadavath, J. Mohan, S. Ashraf, A. Kassier, D. Hawwass, N. Madan, N. Salehi, M. Bernardo, M. C. Kim, M. C. Alraies, +13 Additional Authors Jan 2020

Cardiac Catheterization Laboratory Volume Changes During Covid-19—Findings From A Cardiovascular Fellows Consortium, S. Kadavath, J. Mohan, S. Ashraf, A. Kassier, D. Hawwass, N. Madan, N. Salehi, M. Bernardo, M. C. Kim, M. C. Alraies, +13 Additional Authors

Journal Articles

No abstract provided.


Guidance For Rebooting Electrophysiology Through The Covid-19 Pandemic From The Heart Rhythm Society And The American Heart Association Electrocardiography And Arrhythmias Committee Of The Council On Clinical Cardiology: Endorsed By The American College Of Cardiology, D. R. Lakkireddy, M. K. Chung, T. F. Deering, R. Gopinathannair, C. M. Albert, L. M. Epstein, C. V. Harding, J. L. Hurwitz, C. C. Jeffery, A. M. Russo, +9 Additional Authors Jan 2020

Guidance For Rebooting Electrophysiology Through The Covid-19 Pandemic From The Heart Rhythm Society And The American Heart Association Electrocardiography And Arrhythmias Committee Of The Council On Clinical Cardiology: Endorsed By The American College Of Cardiology, D. R. Lakkireddy, M. K. Chung, T. F. Deering, R. Gopinathannair, C. M. Albert, L. M. Epstein, C. V. Harding, J. L. Hurwitz, C. C. Jeffery, A. M. Russo, +9 Additional Authors

Journal Articles

© 2020 The Heart Rhythm Society, the American Heart Association, Inc., and the American College of Cardiology Foundation Coronavirus disease 2019 (COVID-19) has presented substantial challenges to patient care and impacted health care delivery, including cardiac electrophysiology practice throughout the globe. Based upon the undetermined course and regional variability of the pandemic, there is uncertainty as to how and when to resume and deliver electrophysiology services for arrhythmia patients. This joint document from representatives of the Heart Rhythm Society, American Heart Association, and American College of Cardiology seeks to provide guidance for clinicians and institutions reestablishing safe electrophysiological care. To …


Institutional Preparedness Strategies For Heart Failure, Durable Left Ventricular Assist Device, And Heart Transplant Patients During The Coronavirus Disease 2019 (Covid-19) Pandemic, A. Bansal, D. Goldstein, S. Schettle, S. Pepitone, B. Lima, D. T. Pham, J. Cowger, A. Schubert, S. P. Pinney Jan 2020

Institutional Preparedness Strategies For Heart Failure, Durable Left Ventricular Assist Device, And Heart Transplant Patients During The Coronavirus Disease 2019 (Covid-19) Pandemic, A. Bansal, D. Goldstein, S. Schettle, S. Pepitone, B. Lima, D. T. Pham, J. Cowger, A. Schubert, S. P. Pinney

Journal Articles

No abstract provided.


Outcomes In Patients With Severe Covid-19 Disease Treated With Tocilizumab: A Case-Controlled Study, G. Rojas-Marte, M. Khalid, O. Mukhtar, A. T. Hashmi, M. A. Waheed, S. Ehrlich, A. Aslam, S. Siddiqui, C. Agarwal, J. Shani, +8 Additional Authors Jan 2020

Outcomes In Patients With Severe Covid-19 Disease Treated With Tocilizumab: A Case-Controlled Study, G. Rojas-Marte, M. Khalid, O. Mukhtar, A. T. Hashmi, M. A. Waheed, S. Ehrlich, A. Aslam, S. Siddiqui, C. Agarwal, J. Shani, +8 Additional Authors

Journal Articles

© The Author(s) 2020. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For permissions, please email: journals.permissions@oup.com. BACKGROUND: COVID-19 is an ongoing threat to society. Patients who develop the most severe forms of the disease have high mortality. The interleukin-6 inhibitor tocilizumab has the potential to improve outcomes in these patients by preventing the development of cytokine release storm. AIMS: To evaluate the outcomes of patients with severe COVID-19 disease treated with the interleukin-6 inhibitor tocilizumab. METHODS: We conducted a retrospective, case-control, single-center study in patients with severe to critical COVID-19 disease treated …


Response: From Cardiology To Covid The Impact Of A Pandemic On Fellowship Training, J. T. Kuvin Jan 2020

Response: From Cardiology To Covid The Impact Of A Pandemic On Fellowship Training, J. T. Kuvin

Journal Articles

No abstract provided.


Use Of A Smartwatch For Assessment Of The Qt Interval In Outpatients With Coronavirus Disease 2019., J. S. Chinitz, R. Goyal, D. C. Morales, M. Harding, S. Selim, L. M. Epstein Jan 2020

Use Of A Smartwatch For Assessment Of The Qt Interval In Outpatients With Coronavirus Disease 2019., J. S. Chinitz, R. Goyal, D. C. Morales, M. Harding, S. Selim, L. M. Epstein

Journal Articles

The coronavirus disease 2019 (COVID-19) pandemic has necessitated rapid implementation of innovative strategies to manage patients remotely to help reduce the risk of community and nosocomial transmission. This case demonstrates the use of an Apple Watch (Apple, Cupertino, CA, USA) to monitor for arrhythmias and QT prolongation in a patient with COVID-19 during home isolation.


Usefulness Of Elevated Troponin To Predict Death In Patients With Covid-19 And Myocardial Injury., D. T. Majure, L. Gruberg, S. G. Saba, C. Kvasnovsky, J. S. Hirsch, R. Jauhar, Northwell Health Covid-19 Research Consortium Jan 2020

Usefulness Of Elevated Troponin To Predict Death In Patients With Covid-19 And Myocardial Injury., D. T. Majure, L. Gruberg, S. G. Saba, C. Kvasnovsky, J. S. Hirsch, R. Jauhar, Northwell Health Covid-19 Research Consortium

Journal Articles

Elevations in troponin levels have been shown to predict mortality in patients with coronavirus disease 2019 (COVID-19). The role of inflammation in myocardial injury remains unclear. We sought to determine the association of elevated troponin with mortality in a large, ethnically diverse population of patients hospitalized with COVID-19, and to determine the association of elevated inflammatory markers with increased troponin levels. We reviewed all patients admitted at our health system with COVID-19 from March 1 to April 27, 2020, who had a troponin assessment within 48 hours of admission. We used logistic regression to calculate odds ratios (ORs) for mortality …


We May Develop Medications Effective Against Covid-19, But Can We Distribute Them Equitably?, D. J. Kersten, A. N. Makaryus Jan 2020

We May Develop Medications Effective Against Covid-19, But Can We Distribute Them Equitably?, D. J. Kersten, A. N. Makaryus

Journal Articles

No abstract provided.


Impact Of Covid-19 Pandemic On Stemi Care: An Expanded Analysis From The United States., S. Garcia, L. Stanberry, C. Schmidt, S. Sharkey, M. Megaly, M. S. Albaghdadi, P. M. Meraj, R. Garberich, H. Khalili, T. D. Henry, +20 Additional Authors Jan 2020

Impact Of Covid-19 Pandemic On Stemi Care: An Expanded Analysis From The United States., S. Garcia, L. Stanberry, C. Schmidt, S. Sharkey, M. Megaly, M. S. Albaghdadi, P. M. Meraj, R. Garberich, H. Khalili, T. D. Henry, +20 Additional Authors

Journal Articles

OBJECTIVE: To evaluate the impact of COVID-19 pandemic migitation measures on of ST-elevation myocardial infarction (STEMI) care.

BACKGROUND: We previously reported a 38% decline in cardiac catheterization activations during the early phase of the COVID-19 pandemic mitigation measures. This study extends our early observations using a larger sample of STEMI programs representative of different US regions with the inclusion of more contemporary data.

METHODS: Data from 18 hospitals or healthcare systems in the US from January 2019 to April 2020 were collecting including number activations for STEMI, the number of activations leading to angiography and primary percutaneous coronary intervention (PPCI), …


Management Of Covid-19 Myopericarditis With Reversal Of Cardiac Dysfunction After Blunting Of Cytokine Storm: A Case Report., A. Li, Y. Garcia-Bengochea, R. Stechel, B. M. Azari Jan 2020

Management Of Covid-19 Myopericarditis With Reversal Of Cardiac Dysfunction After Blunting Of Cytokine Storm: A Case Report., A. Li, Y. Garcia-Bengochea, R. Stechel, B. M. Azari

Journal Articles

Background:Coronavirus disease 2019 (COVID-19) is a syndrome that has been associated with multiple cardiac complications including myopericarditis. The pathophysiology and treatment for myopericarditis in the setting of COVID-19 infection is still under investigation. Case summary:We present a case of a 60-year-old male admitted for dyspnoea due to COVID-19. He developed new ST-segment elevation, elevated cardiac enzymes, severe left ventricular dysfunction, and high inflammatory markers in the setting of haemodynamic and respiratory collapse from the viral illness. He was diagnosed with COVID-19-induced myopericarditis. He showed rapid clinical improvement with a rapid wean off pressure support, resolution of electrocardiogram (ECG) findings, and …


Diagnostic And Treatment Utility Of Echocardiography In The Management Of The Cardiac Patient, A. Khalili, J. Drummond, N. Ramjattan, R. Zeltser, A. N. Makaryus Jan 2020

Diagnostic And Treatment Utility Of Echocardiography In The Management Of The Cardiac Patient, A. Khalili, J. Drummond, N. Ramjattan, R. Zeltser, A. N. Makaryus

Journal Articles

© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. BACKGROUND Echocardiograms are an incredibly useful diagnostic tool due to their lack of harmful radiation, the relative ease and speed with which they can be performed, and their almost ubiquitous availability. Unfortunately, the advantages that support the use of echocardiography can also lead to the overuse of this technology. We sought to evaluate the physician perceived impact echocardiography has on patient management. AIM To evaluate the physician perceived impact echocardiography has on patient management. METHODS Surveys were distributed to the ordering physician for echocardiograms performed at our …


Preoperative Nuclear Stress Testing In The Very Old Patient Population, A. N. Makaryus, J. N. Makaryus, J. A. Diamond Jan 2020

Preoperative Nuclear Stress Testing In The Very Old Patient Population, A. N. Makaryus, J. N. Makaryus, J. A. Diamond

Journal Articles

© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. BACKGROUND Elderly patients awaiting moderate to high-risk surgery may undergo nuclear stress testing (NST) in order to evaluate their cardiovascular risk. The prognostic utility of such testing in the very elderly (≥ 85 years) has yet to be fully evaluated. Octogenarians and nonogenarians frequently have a number of concurrent conditions including a high rate of coronary disease, and therefore the prognostic value of NST for their preoperative risk assessment has been questioned. Our evaluation assesses the ability of nuclear stress testing to predict peri-operative cardiac outcomes in …


Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic, N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. I. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors Jan 2020

Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic, N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. I. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors

Journal Articles

No abstract provided.


Impact Of Cardiologist Intervention On Guideline-Directed Use Of Statin Therapy, M. Cassagnol, O. Hai, S. A. Sherali, K. D'Angelo, D. Bass, R. Zeltser, A. N. Makaryus Jan 2020

Impact Of Cardiologist Intervention On Guideline-Directed Use Of Statin Therapy, M. Cassagnol, O. Hai, S. A. Sherali, K. D'Angelo, D. Bass, R. Zeltser, A. N. Makaryus

Journal Articles

© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. BACKGROUND Statins have an important and well-established role in the prevention of atherosclerotic cardiovascular disease (ASCVD). However, several studies have reported widespread underuse of statins in various practice settings and populations. Review of relevant literature reveals opportunities for improvement in the implementation of guideline-directed statin therapy (GDST). AIM To examine the impact of cardiologist intervention on the use of GDST in the ambulatory setting. METHODS Patients with at least one encounter at the adult Internal Medicine Clinic (IMC) and/or Cardiology Clinic (CC), who had an available serum …