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Full-Text Articles in Medicine and Health Sciences
Basement Membrane And Repair Of Injury To Peripheral Nerve: Defining A Potential Role For Macrophages, Matrix Metalloproteinases, And Tissue Inhibitor Of Metalloproteinases-1, Monique La Fleur, Johnnie L. Underwood, Daniel A. Rappolee, Zena Werb
Basement Membrane And Repair Of Injury To Peripheral Nerve: Defining A Potential Role For Macrophages, Matrix Metalloproteinases, And Tissue Inhibitor Of Metalloproteinases-1, Monique La Fleur, Johnnie L. Underwood, Daniel A. Rappolee, Zena Werb
Department of Obstetrics and Gynecology Research Publications
Injury to a peripheral nerve is followed by a remodeling process consisting of axonal degenera- tion and regeneration. It is not known how Schwann cell–derived basement membrane is pre- served after injury or what role matrix metalloproteinases (MMPs) and their inhibitors play in axonal degeneration and regeneration. We showed that the MMPs gelatinase B (MMP-9), stromelysin-1 (MMP-3), and the tissue inhibitor of MMPs (TIMP)-1 were induced in crush and distal segments of mouse sciatic nerve after injury. TIMP-1 inhibitor activity was present in excess of proteinase activity in extracts of injured nerve. TIMP-1 protected basement mem- brane type IV collagen …
Competitive Orientations And Motives Of Adult Sport And Exercise Participants, Diane L. Gill, Lavon Williams, Deborah A. Dowd, Christina M. Beaudoin, Jeffrey J. Martin
Competitive Orientations And Motives Of Adult Sport And Exercise Participants, Diane L. Gill, Lavon Williams, Deborah A. Dowd, Christina M. Beaudoin, Jeffrey J. Martin
Kinesiology, Health and Sport Studies
Participants in four different adult sport and exercise programs (running club, exercise classes, cardiac rehabilitation program, senior games) completed measures of competitive orientation and participation motivation. Our samples were older and more diverse than samples of previous research, and their competitive orientations and motives were similarly diverse. Multivariate analyses revealed gender and sample differences. Males were higher than females on competitiveness and win orientation, and runners were less win-oriented than other groups, but overall, all groups were similar to previous college-age samples in competitive orientation. Groups varied on specific motives, with females rating fitness, flexibility, affiliation, and appearance higher than …
When Are Research Findings Ready For Use?, Judith A. Floyd
When Are Research Findings Ready For Use?, Judith A. Floyd
Nursing Faculty Research Publications
No abstract provided.
Hepatocyte Growth Factor And Its Receptor Are Expressed In Cardiac Myocytes During Early Cardiogenesis, Daniel A. Rappolee, Anand Iyer, Yogesh Patel
Hepatocyte Growth Factor And Its Receptor Are Expressed In Cardiac Myocytes During Early Cardiogenesis, Daniel A. Rappolee, Anand Iyer, Yogesh Patel
Department of Obstetrics and Gynecology Research Publications
In the mouse, the heart primordium arises when mesodermis set aside during gastrulation, is induced by pharyngeal endoderm, migrates ventrally to the midline of the embryo, forms a tube, and begins beating. Little is known of the molecular mechanisms that mediate the determination, mitosis, differentiation, and migration that lead to the beating heart. Transcripts for hepatocyte growth factor/scatter factor (HGF) and its receptor are coexpressed transiently and dynamically in the premyocardium but not in other heart progenitor cells. Transcripts for HGF ligand and receptor are first detected before cardiac function and looping and persist through the first looping stage, when …
Social Support Mechanisms Among Athletes With Disabilities, Jeffrey J. Martin, Carol Adams Mushett
Social Support Mechanisms Among Athletes With Disabilities, Jeffrey J. Martin, Carol Adams Mushett
Kinesiology, Health and Sport Studies
The purpose of this investigation was to describe social support mechanisms of swimmers with disabilities and examine relationships among social support, self-efficacy, and athletic satisfaction. Results indicated that athletes felt satisfied with the social support they received. Mothers and friends provided primary support in a variety of areas requiring non-sport-related knowledge. Additionally, there were important secondary sources of support in areas requiring sport-specific knowledge. Coaches were primary sources of support in areas that required sport expertise. Fathers were also important sources of secondary support in areas that required both sport expertise and nonsport expertise. Correlational results suggested that athletes who …