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Medicine and Health Sciences Commons

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Virginia Commonwealth University

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2022

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Articles 31 - 60 of 68

Full-Text Articles in Medicine and Health Sciences

Giving It All You’Ve Got: The Value Of Extending Hours In An Academic Health Sciences Library, G.J. Corey Harmon, Kerry Sewell Jan 2022

Giving It All You’Ve Got: The Value Of Extending Hours In An Academic Health Sciences Library, G.J. Corey Harmon, Kerry Sewell

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Objective

University libraries’ student satisfaction surveys regularly reveal student demand for increased operating hours to accommodate student learning. While academic libraries may provide extended hours, use of such models in academic health sciences libraries appears to be less widely adopted, perhaps due to budgetary concerns and lower general gate counts than academic library counterparts that may already provide extended hours. In the face of student demands, our institution shifted its budget to provide an additional 10 weekend hours, between Friday and Sunday, to help meet these demands. This study assessed the return on investment for those increased hours by tracking …


Mapping It Out: Developing A Library Internship Program, Emily Hurst, Roy E. Brown, John Cyrus Jan 2022

Mapping It Out: Developing A Library Internship Program, Emily Hurst, Roy E. Brown, John Cyrus

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

Newly graduated librarians often do not possess the knowledge and skills essential to practicing in a health sciences library. This mismatch in experience and expectations stems from a lack of exposure to health sciences librarianship and the typically general nature of graduate education in library and information science. This gap in skills and understanding stems from a lack of opportunities to develop in these areas. At the same time, many experienced health sciences librarians do not have the supervisory roles as a regular part of their work, resulting in fewer opportunities to build managerial skills and experience. In 2019 …


Resources For Osteopathic Medicine, Elaine Powers, Jessica Muller Jan 2022

Resources For Osteopathic Medicine, Elaine Powers, Jessica Muller

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background


Collection development for Colleges of Osteopathic Medicine (COMs) has been a challenge since strictly osteopathic resources are somewhat specialized in regard to content and acquisition.

Description

This poster will present a list of textbooks and journals needed to develop an osteopathic library collection. Organizations and publishers with osteopathic resources will also be described.

Conclusions

A “top ten” list of osteopathic titles as well as a comprehensive list of osteopathic books and resources provide collection development guidelines for Colleges of Osteopathic Medicine as well as for librarians in other types of medical facilities. Creation of a QR code will provide …


Adventures By Stepping Out Of The Library, Helen-Ann Brown Epstein Jan 2022

Adventures By Stepping Out Of The Library, Helen-Ann Brown Epstein

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

As a solo hospital librarian with a totally digital library, I am free to step out of the Library. Also, the Library organizationally placed on the Clinical Learning Team presents many interesting adventures for an information professional.

Description

This Lightning Talk will describe an ambitious daily rounding schedule, a month of direct observing to help out during the COVID period, active participation on the Nursing Research Council and Family and Patient Education Committee, work with the Nurse Residents and advising a vendor on a new product.

Conclusions

By stepping out of the Library, the Librarian can show support and …


Successes And Challenges Of Being Interim Leaders During A Pandemic, Roy E. Brown, John Cyrus, Emily Hurst Jan 2022

Successes And Challenges Of Being Interim Leaders During A Pandemic, Roy E. Brown, John Cyrus, Emily Hurst

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

Assuming an interim leadership role presents personal opportunities for professional growth and organizational challenges. These challenges may stem from the temporary nature of the position and a lack of clear direction or decision-making authority. External forces, in this case the COVID-19 pandemic, also contribute to interim leaders' challenges. Library administration at a large public research university with multiple interim positions worked to identify potential challenges and possible solutions for those designated to interim leadership roles.

Description

This session will describe a plan created to facilitate the transition into and out of interim positions, set expectations for these roles, and …


Roll For Initiative! 101 Just Leveled Up: Choosing Intentionality In Course Redesign, Jennifer Monnin, Faythe Thurman, Kelly Diamond, Celia Shi, David Roth, Virginia Desouky Jan 2022

Roll For Initiative! 101 Just Leveled Up: Choosing Intentionality In Course Redesign, Jennifer Monnin, Faythe Thurman, Kelly Diamond, Celia Shi, David Roth, Virginia Desouky

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background:

As demand for the health sciences (HS) section of the Library's introductory credit-bearing information literacy course outpaced available course seats and after a change to the course registration software made the section difficult to locate, a need was identified to update the coursework to be more relevant to HS students' specific learning needs. Three HS librarians and the Libraries' Office of Curriculum and Instructional Support (OCIS) collaborated to revamp this section to better meet the needs of future healthcare professionals. The revamped coursework was instituted beginning Fall 2021, and in Fall 2022 the section became its own unique class. …


Free, Fair, And Fabulous: Five Data Tools To Support Open And Reproducible Research At Your Institution, Christine Nieman, Katie Pierce-Farrier, Sean Corning, Elizabeth Roth Jan 2022

Free, Fair, And Fabulous: Five Data Tools To Support Open And Reproducible Research At Your Institution, Christine Nieman, Katie Pierce-Farrier, Sean Corning, Elizabeth Roth

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

With more publishers and funders requiring data management and sharing plans, it is important for librarians, researchers, and support staff to be aware of the tools available to help them skillfully manage research data. There are a wide variety of tools available, both free and paid, that can work with data but selecting an affordable, accessible tool can be a barrier to use.

Description

This poster seeks to promote awareness of freely available tools for data management, wrangling, and sharing for use in daily work and research projects. The poster will review five data tools (DMPTool, NIH Common Data …


Setting Off On A New Path: Reimaging A Library Department Annual Report, Jackson Hoch, Roy E. Brown, Emily Hurst Jan 2022

Setting Off On A New Path: Reimaging A Library Department Annual Report, Jackson Hoch, Roy E. Brown, Emily Hurst

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

Academic libraries annually produce reports highlighting the previous year's achievements while highlighting new resources, services, and programs. These are intended to communicate with different groups with different interests. The library in these reports must discuss what was done and how those activities provided value to the community of users. The librarians at a large public research university debated the effectiveness of the annual report produced within their department. An internship project was created to rethink the department’s annual report and develop a plan to determine its effectiveness. The project intended to allow the intern to learn more about how …


Book It Forward: An Engaging Community Project, Jessica Bauer, M. J. Tooey Jan 2022

Book It Forward: An Engaging Community Project, Jessica Bauer, M. J. Tooey

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

A two-fold need was identified in our community:

  1. Parents and caregivers frequently have a need to do something with books their children have outgrown or left behind.
  2. Many schools and daycare centers in the local community served by our university don’t have adequate books and reading materials for students and have a need to boost their libraries. Working with the university’s Community Engagement Center, the library launched a two-month book collection drive on campus.

Description

Staff from across the library created announcements and graphics promoting the drive and developed criteria for accepted donations. The team reached out to contacts …


Online Escape Rooms: What Do The Students Think?, Emily Gorman Jan 2022

Online Escape Rooms: What Do The Students Think?, Emily Gorman

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Objective

Gamification is an increasingly popular teaching method for enhancing student engagement during instruction. Multiple learning games have been used over the last several years to introduce first-year pharmacy students to library and drug information resources. The purpose of this study was to evaluate the efficacy of an online escape room-style game and to investigate student perspectives on this style of learning.

Methods

A librarian developed an online escape room-style learning game and facilitated the activity with first-year pharmacy students as part of their introductory laboratory course in Fall 2020. The escape room was adapted from a previously successful in-person …


Adventuring Into A University Common Read Program, Emily Hurst Jan 2022

Adventuring Into A University Common Read Program, Emily Hurst

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

Each year a selection committee at a large urban university selects a book for all first year students. Books are sent out to students and then the title is used throughout many freshman level classes. Librarians are involved in the selection of the book, the creation of a resource guide with related information, and the creation of potential programs to support the themes and topics addressed in the book. The largest event is organized through the common read program and involves a lecture to the university community from the book author. For many years the book and common read …


The Self-Taught Marketers Guide To Creating An Annual Report, Everly D. Brown, Patrick T. Waugh, Tara R. Wink Jan 2022

The Self-Taught Marketers Guide To Creating An Annual Report, Everly D. Brown, Patrick T. Waugh, Tara R. Wink

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Objective

To produce an easy-to-read, visually appealing, 1-4 page annual report for the University of Maryland, Baltimore’s Health Sciences and Human Services Library (HSHSL). The report should be a mix of interesting statistics, highlights, stories, quotes, and photographs to promote the HSHSL’s annual accomplishments to the campus.

Methods

We gather all of the stories and statistics we think will be eligible material for the annual report, pulling content and ideas from: newsletters, workshops, blog posts, events, exhibits, and meetings with division and department heads. An annual report committee and visual designer decide upon the top stories and statistics, focusing upon …


Foxos Modulate Proteasome Activity In Human-Induced Pluripotent Stem Cells Of Huntington’S Disease And Their Derived Neural Cells, Jefin Jose Jan 2022

Foxos Modulate Proteasome Activity In Human-Induced Pluripotent Stem Cells Of Huntington’S Disease And Their Derived Neural Cells, Jefin Jose

VCU's Medical Journal Club: The Work of Future Health Professionals

FOXO transcription factors have been implicated in modulating proteasome activity. Liu et al. found that Huntington's disease-induced pluripotent stem cells (HD iPSCs) exhibited greater proteasome activity as well as greater FOXO1 and FOXO4 expression. To determine a possible causal relationship, Liu et al. performed shRNA knockout of these two transcription factors and found that only FOXO4 mediated proteasome activity in pluripotent stem cells. Overexpression of FOXO4 rescued proteasomal defect in HD iPSCs-derived neural progenitor cells (NPCs). Overall, Liu et al. found that FOXO4 specifically modulated proteasome activity in HD iPSCs and their derived NPCs.


Slow-Stroke Back Massage Compared With Music Therapy For Leukemia-Related Pain And Fatigue: A Randomized Controlled Trial, Rhea Tammireddi Jan 2022

Slow-Stroke Back Massage Compared With Music Therapy For Leukemia-Related Pain And Fatigue: A Randomized Controlled Trial, Rhea Tammireddi

VCU's Medical Journal Club: The Work of Future Health Professionals

This presentation focused on the effects of nonpharmacological treatments for leukemia-related pain and fatigue. These types of treatments are becoming more prevalent in today's times due to the risk of opioid addictions with increased pain medications. The study looked at two treatments: slow-back massage therapy and music therapy. Both treatments offer various advantages physically and emotionally. The study separated 114 adults with acute myeloid leukemia into the two treatments group and a control group of standard treatment. The results showed back massage therapy had a stronger and longer effect on the reduction of pain and fatigue.


End Stage Recurrent Glioblastoma Treated With A New Noninvasive Non-Contact Oncomagnetic Device, Devam Purohit Jan 2022

End Stage Recurrent Glioblastoma Treated With A New Noninvasive Non-Contact Oncomagnetic Device, Devam Purohit

VCU's Medical Journal Club: The Work of Future Health Professionals

This presentation focused on the use of a noninvasive oncomagnetic device for glioblastoma. This treatment is special because it is noninvasive and doesn't pose the side effects of chemotherapy or surgery. The study looked at how the oncomagnetic device affected the size of the tumor after it reappeared in the patient's brain after being surgically removed initially. The device was tested on one patient and it was able to reduce his tumor by 31%.


Anti-Gd2 Antibody Dinutuximab Inhibits Triple-Negative Breast Tumor Growth By Targeting Gd2+ Breast Cancer Stem-Like Cells, Nasser Al-Abdulaly Jan 2022

Anti-Gd2 Antibody Dinutuximab Inhibits Triple-Negative Breast Tumor Growth By Targeting Gd2+ Breast Cancer Stem-Like Cells, Nasser Al-Abdulaly

VCU's Medical Journal Club: The Work of Future Health Professionals

Triple negative breast cancer is an aggressive subtype of breast cancer characterized by its lack of estrogen and progesterone receptors, as well as no or low levels of human epidermal growth factor 2. Ly et al. found that the ganglioside GD2 is highly expressed in a stem cell-like population of triple negative breast cancer tumor and helps with cell adhesion and migration. Using a xenograft model, the researchers determined that targeting this cell population with dinutuximab (anti-GD2 antibody) could prevent tumor growth and metastasis.


Association Of Cag Repeats With Long-Term Progression In Huntington Disease, Jefin Jose Jan 2022

Association Of Cag Repeats With Long-Term Progression In Huntington Disease, Jefin Jose

VCU's Medical Journal Club: The Work of Future Health Professionals

The relationship between CAG repeat length and clinical/morphometric decline in Huntington's disease patients beyond the age of onset has not been well characterized. Some studies argue that CAG repeat length does influence clinical decline after the age of onset, while others do not. Langbehn et al. found that clinical condition correlated quadratically with age for every subject with a pathogenic number of CAG repeats in the TRACK-HD and TRACK-ON datasets. Interestingly, those with a higher CAG repeat length experienced a greater rate of clinical decline at each timepoint. Performing a similar analysis using morphometric data, Langbehn et al. found a …


Dermatologic Manifestations Of Rheumatic Disease: Cutaneous Manifestations Of Sarcoidosis, Sarah Shapiro, Sindhuja Koppu, Mavra Masood, Beth Rubinstein, Huzaefah Syed Jan 2022

Dermatologic Manifestations Of Rheumatic Disease: Cutaneous Manifestations Of Sarcoidosis, Sarah Shapiro, Sindhuja Koppu, Mavra Masood, Beth Rubinstein, Huzaefah Syed

Open and Affordable Course Content at VCU

Cutaneous Manifestations of Sarcoidosis is a Powerpoint based learning module that depicts fictional patient scenarios detailing sarcoidosis and erythema nodosum. It explores other cutaneous and non-cutaneous manifestations, diagnostic criteria, and medical evaluation of sarcoidosis and the possible etiologies, workup, treatment, and prognosis of erythema nodosum. Health and racial disparities experienced by patients with sarcoidosis are also highlighted and discussed. It takes approximately 25 minutes to complete. This module was created for use in the VCU School of Medicine M1 Movement block, Rheumatology and Dermatology sections.

It is part of the Dermatologic Manifestations of Rheumatic Disease project, which provides overviews of …


Cauti: Are We Testing Appropriately?, Christoph Lecznar Jan 2022

Cauti: Are We Testing Appropriately?, Christoph Lecznar

VCU Health Nursing

Purpose: The purpose of this evidence-based quality improvement project was to decrease catheter associated urinary tract infections in a 28 bed Surgical Trauma Intensive Care Unit in a Level One Trauma Academic Medical Center.

Background: Catheter Associated Urinary Tract Infections (CAUTI) are deemed never events by the Centers for Medicare & Medicaid Services. Centers for Disease Control and Prevention estimates 17-69% of CAUTIs are preventable. Current recommendations for CAUTI reduction include: Education strategies, chlorhexidine gluconate bathing and catheter care, catheter avoidance, policies for insertion, and urine culture testing stewardship. Our unit experienced an increase in CAUTI incidence in May and …


Violence Prevention Task Force: A Health System’S Journey Towards Zero, Lisa Davis, Denise Holyoak Jan 2022

Violence Prevention Task Force: A Health System’S Journey Towards Zero, Lisa Davis, Denise Holyoak

VCU Health Nursing

VCU Health's mission is to be the safest most caring hospital with zero events of preventable harm to patients, team members, and visitors. Our goal cannot be achieved if our staff suffer from workplace violence injuries thus, our executive leaders sponsored a Violence Task Force in 2017 comprised of leaders and bedside staff from all disciplines to implement evidence-informed strategies to aid in the prevention, response or recovery to a violent event. Review of data and measures of our outcomes are based on our worker's compensation, behavioral rapid response, and safety culture surveys. Event drill-downs are achieved by our post-assault …


Climate Change And Mental Health: What Can We Do?, Ann N. Welch Jan 2022

Climate Change And Mental Health: What Can We Do?, Ann N. Welch

VCU Health Nursing

Climate change has been described as the defining health issue of this century. Many aspects of mental health are affected by the events related to the earth's warming climate. This poster presentation will identify ways in which climate change affects mental health and suggest concrete actions that can be taken to help to mitigate these effects.


Using Silicone Mesh To Mitigate Risk Of Forehead Pulse Ox Pressure Injuries, Patrick Alridge Jan 2022

Using Silicone Mesh To Mitigate Risk Of Forehead Pulse Ox Pressure Injuries, Patrick Alridge

VCU Health Nursing

Introduction

In the intensive care unit (ICU) setting, patients may require the use of a pulse ox probe on the forehead to obtain an appropriate oxygenation saturation reading. The pulse ox probe has two clear plastic sensors, through which the infrared light travels to measure oxygenation. Despite applying the sensor per manufacturer’s instructions and rotating the device location on the forehead more frequently than manufacturer recommendations, the sensor can still cause a medical device-related pressure injury.

Methods

Silicone mesh dressing is commonly used under wet to dry dressings or under negative pressure wound therapy dressings to prevent adherence of the …


What Matters Most: Cna Perspectives On Workforce Education, Professional Identity And Age-Friendly Care, Shannon Arnette, Annie Rhodes, Kimberly Ivey, Christian Bergman, Leland "Bert" Waters Jan 2022

What Matters Most: Cna Perspectives On Workforce Education, Professional Identity And Age-Friendly Care, Shannon Arnette, Annie Rhodes, Kimberly Ivey, Christian Bergman, Leland "Bert" Waters

Case Studies from Age in Action

Learning Objectives

1. Identify the gaps in current Certified Nursing Assistant (CNA) training in relation to Delirium, Dementia(s), and Depression (3D’s).

2. Identify CNA learning preferences.

3. Review the constructed tele-education training sessions that incorporate age-friendly care and What Matters Most (WMM) to participants in regards to the 3D’s.

4. Increase the CNAs’ competency and level of comfort working with individuals living with the 3D’s.


Recognizing And Responding To Abuse In Later Life: Feedback From Virginia’S Frontline, Sarah A. Marrs, Courtney O'Hara Jan 2022

Recognizing And Responding To Abuse In Later Life: Feedback From Virginia’S Frontline, Sarah A. Marrs, Courtney O'Hara

Case Studies from Age in Action

Learning Objectives

1. To describe a research project aimed at understanding the recognition of and response to abuse in later life in the greater Richmond area

2. To discuss the structural factors that contribute to underidentification and under-resourcing of services that address abuse in later life

3. To discuss the relationship between ageism and abuse in later life


Coping With Macular Degeneration: Three Case Studies, Ajit D. Tiwari Jan 2022

Coping With Macular Degeneration: Three Case Studies, Ajit D. Tiwari

Case Studies from Age in Action

Educational Objectives

1. Learn about the diagnosis and available treatments for Age Related Macular Degeneration (AMD).

2. Explain the differences between Dry and Wet AMD.

3. Understand the impact of vision loss on the lives of older adults.


Adult-Onset Alexander Disease Uncovered In A Previously Healthy Patient Presenting With Acute Stroke-Like Symptoms, Usaamah M. Khan, Matthew Barrett, Alex Dworetz Do Jan 2022

Adult-Onset Alexander Disease Uncovered In A Previously Healthy Patient Presenting With Acute Stroke-Like Symptoms, Usaamah M. Khan, Matthew Barrett, Alex Dworetz Do

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Alexander Disease is a rare, often fatal, leukoencephalopathy of early childhood associated with a heterozygous mutation of the glial fibrillary acid protein (GFAP) gene. Adult-Onset Alexander Disease (AOAD) is an exceptionally rare leukoencephalopathy that often presents with slowly progressive brainstem and cervical cord dysfunction features. Acute onset of AOAD has only ever been reported three times in the literature. We report a case of acute onset AOAD in a patient that presented with bulbar symptoms and left hemiplegia initially concerning for acute stroke.


Patient And Provider-Level Factors That Underlie Alcohol Use Disorder Treatment Offer And Acceptance In Veterans With Cirrhosis, Nikki Duong Jan 2022

Patient And Provider-Level Factors That Underlie Alcohol Use Disorder Treatment Offer And Acceptance In Veterans With Cirrhosis, Nikki Duong

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Background: Untreated alcohol use disorder (AUD) is associated with poor cirrhosis outcomes. We evaluated factors associated with AUD treatment discussions and initiation in the Veterans Health Administration.

Methods: Chart reviews were conducted for veterans with International Classification of Diseases codes for both cirrhosis and AUD who were receiving care at one of three large medical centers in 2020. Factors associated with a 1-year offer of AUD treatment and its acceptance were assessed using regression models, which included as covariates demographic characteristics, comorbidities, and depression, as measured by the patient health questionnaire (PHQ-2) from the electronic health record.

Results: The cohort …


Characterizing Abdominal Pain In Patients With Gastroparesis, Dylan Vainer, Henry Parkman, Dariush Shahsavari Jan 2022

Characterizing Abdominal Pain In Patients With Gastroparesis, Dylan Vainer, Henry Parkman, Dariush Shahsavari

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

TITLE: CHARACTERIZING ABDOMINAL PAIN IN PATIENTS WITH GASTROPARESIS

AUTHORS (LAST NAME, FIRST NAME): Vainer, Dylan1; Shahsavari, Dariush2; Parkman, Henry P.2

INSTITUTIONS (ALL): 1. Section of Gastroenterology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States. 2. Temple University Health System Inc, Philadelphia, PA, United States.

ABSTRACT BODY: Introduction: Patients with gastroparesis (Gp) typically present with nausea, vomiting, and early satiety. Abdominal pain can be present in Gp. The cause of abdominal pain in patients with Gp is often unknown. In patients whose predominant symptom is abdominal pain, other causes of abdominal pain …


Lessons Learned From Inspire Super-Performers, Thomas H. Fitzpatrick Iv, Ryan S. Nord Jan 2022

Lessons Learned From Inspire Super-Performers, Thomas H. Fitzpatrick Iv, Ryan S. Nord

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Objective: The purpose of this study is to examine what demographic factors correlate with greater rates of upper airway stimulation adherence and efficacy.

Study Design: Case control study

Introduction:

Upper airway stimulation (UAS) is emerging as an effective procedure for select patients with obstructive sleep apnea. As initially studied, this procedure is reserved for those exhibiting body mass index (BMI)

Methods:

We queried a single surgeon’s database of UAS cases, totaling 97 at the time of study. The electronic medical record (EMR) was queried for each patient and pertinent demographics were recorded. We began by defining cohorts: super-adherers were …


Antinociceptive Effects Of G-Protein Biased Mu Opioid Receptor Agonists In Male And Female Rats With Chemotherapy-Induced Neuropathy, Tilak Patel Md Jan 2022

Antinociceptive Effects Of G-Protein Biased Mu Opioid Receptor Agonists In Male And Female Rats With Chemotherapy-Induced Neuropathy, Tilak Patel Md

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Aim: Mu-opioid receptor (MOR) agonists are often prescribed for the treatment of chemotherapy-induced neuropathy (CIN). Recent drug development strategies have focused on opioids with signaling profiles that “bias” activation of specific intracellular pathways (e.g., G-protein signaling) over others with the aim of increasing therapeutic selectivity. However, it is unknown if the variances in these signaling profiles at the MOR differentially modulate the antinociceptive effects of MOR agonists against neuropathic pain. In the present study, we tested a series of MOR agonists of varying G-protein signaling bias in a rat model of CIN. Methods: CIN was induced in male and female …