Medicine and Health Sciences Commons^™

Frontiers (Summer 2011) - Five Centers Of Excellence: One Source For Comprehensive Care, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.

Advance (Summer 2011) - Finding A Link: Genetics And Concussion, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Advance Research Digest

No abstract provided.

Volume 8, Number 1 (Spring/Summer 2011), Ut Institute Of Agriculture

Tennessee Land, Life and Science Magazine

Issue Highlights:

• Planting a Garden of Hope for Cancer Patients
• In Smith County, a Community Reinvents Itself
• Advancing Tennessee Through Strategic Extension

Why Is There Still So Much Confusion About Vo2 Plateau? A Re-Examination Of The Work Of A.V. Hill, Richard Vincent Castle

Masters Theses

Maximal oxygen uptake (VO_2max) is regarded as the gold standard for assessing aerobic fitness. In 1923, Hill et al. proposed that VO_2max represents the maximal ability of the body to take in and consume O₂ during strenuous exercise. Recently, however, controversy has arisen over the issue of whether a leveling off, or "plateau" in VO₂ is necessary to verify attainment of VO_2max. Purpose: To compare two different VO_2max protocols and determine if both protocols show direct evidence of an upper limit on VO₂. Methods: Nine runners (18-35 years old) completed …

Mechanism Of Phospholipid Induction Of Cell Migration, Dongwei Wu

Doctoral Dissertations

Lysophosphatidic acid (LPA) is a potent bioactive lipid component of oxidized low density lipoproteins (oxLDL). High concentrations of LPA have been detected in human atherosclerotic plaques. Our data has shown that LPA highly induces smooth muscle cell (SMC) migration. Cyr61, a matricellular protein, which also accumulates in human atherosclerotic plaques, has been implicated in the injury-induced neointimal formation. Smooth muscle cell migration is a key event in the development of atherosclerosis, and it contributes to the progressive growth of atherosclerotic lesions. Data generated by this study demonstrate that LPA markedly induces Cyr61 expression in mouse aortic smooth muscle cells (MASMC). …

The Relationship Between Self-Directedness And Health Promotion In The Elderly, Barbara L Hulsman

Doctoral Dissertations

With the number of people living longer and with more chronic problems, it is important that health educators examine who they are educating as well as the methods and circumstances of the education. The purpose of this study was to identify the relationship between self-directedness and health promotion in the elderly. A convenience sample of 108 elders who use Senior Centers in rural East Tennessee comprised the study group. The sample was asked to complete the Self-Directed Learning Readiness Scale, the Health Promoting Lifestyle Profile II, and a demographic information survey at a regular meeting of a Senior Center. A …

Chemical Tools To Characterize Membrane-Protein Binding Interactions Using Synthetic Lipid Probes, Meng Meng Rowland

Doctoral Dissertations

Signaling lipids such as diacylglycerol (DAG) and the phosphatidylinositol polyphosphates (PIP_ns) play crucial roles in numerous cellular pathways. However, characterization of their activities is hindered by the complexity of associated signaling pathways and of the membrane environment. To address this issue, we have developed lipid probes that are effective for characterizing biological events using different applications, including activity-based probing (PIP_ns and DAG) and microarray analysis (PIP_ns). The activity-based probes have been applied to label receptor targets in multiple cancer cell proteomes through photocrosslinking followed by click reactions. The probes were found to label several …

Development Of An Autonomous Mammalian Lux Reporter System, Daniel Michael Close

Doctoral Dissertations

Since its characterization, the definitive shortcoming of the bacterial luciferase (lux) bioluminescent reporter system has been its inability to express at a functional level in the eukaryotic cellular background. While recent developments have allowed for lux function in the lower eukaryote Saccharomyces cerevisiae, they have not provided for autonomous function in higher eukaryotes capable of serving as human biomedical proxies. Here it is reported for the first time that, through a process of poly-bicistronic expression of human codon-optimized lux genes, it is possible to autonomously produce a bioluminescent signal directly from mammalian cells. The low background of …

“It Can Start From Anything”: An Existential Phenomenological Investigation Of Athletes’ Experiences Of Psychological Momentum, Greg Young

Doctoral Dissertations

Psychological Momentum (PM) is a commonly recognized phenomenon in sport, yet remains one of the least understood (Taylor & Demick, 1994). Previous research examined PM using archival data (Gayton & Very, 1993; Gilovich, Vallone, & Tversky, 1985; Koehler & Conley, 2003; Silva, Hardy, & Crace, 1988), hypothetical and contrived scenarios (Eisler & Spink, 1998; Miller & Weinberg, 1991; Perreault, Vallerand, Montgomery, & Provencher, 1998; Vallerand, Colavecchio, & Pelletier, 1988), and actual performance (Mack, et al., 2008). More recently, Jones and Harwood (2008) used semi-structured interviews to examine participants’ …

Kenshi’S Experiences Of Kendo: A Phenomenological Investigation, Takahiro Sato

Doctoral Dissertations

The aim of this study was to extend existing literature on the martial arts by examining the experience of kendo (Japanese fencing) participants. In-depth, existential phenomenological interviews were conducted with nine (eight males and one female) currently competitive kendo practitioners (i.e., kenshi), ranging in age from 19 to 40 years. All participants were of Japanese descent but resided in the United States at the time of the interviews. Thematic analysis of the transcripts revealed several prominent aspects of the lives and performance experiences of kenshi. The most important finding was the relatively equal emphasis participants placed on the mastery …

Cardiac Kids: Obesity Intervention Program In Elementary School Children, Christen Rose Waddell, Lisa Wagoner, Bonnie Callen, Carolyn Perry-Burst, Aneisa Mcdonald, Marcia Spence

Chancellor’s Honors Program Projects

No abstract provided.

The Therapy Of Humiliation: Towards An Ethics Of Humility In The Works Of J.M. Coetzee, Ajitpaul Singh Mangat

Masters Theses

This work asks how and for whom humiliation can be therapeutic. J. M. Coetzee, in his works Waiting for the Barbarians, Life & Times of Michael K and Disgrace, does not simply critique the mentality of Empire, an “Enlightenment” or colonialist mode of knowing that knows no bounds to reason, but offers an alternative through the Magistrate, Michael K and David Lurie, all of whom are brutally shamed and “abjected”. Each character, I propose, experiences a Lacanian “therapy of humiliation” resulting in a subversion of their egos, which they come to understand as antagonistic, a site of …

Increasing Dietary Linoleic Acid Does Not Increase Tissue Arachidonic Acid Content In Adults Consuming Western- Type Diets, Brian Rett

Masters Theses

Linoleic acid, with a DRI of 12-17g/d, is the most highly consumed polyunsaturated fatty acid in the Western diet and is found in virtually all commonly consumed foods. The concern with dietary linoleic acid, being the metabolic precursor of arachidonic acid, is its consumption may enrich tissues with arachidonic acid and contribute to chronic and overproduction of bioactive eicosanoids. However, no systematic review of human trials regarding linoleic acid consumption and subsequent changes in tissue levels of arachidonic acid has been undertaken. In this study, we reviewed the human literature that reported changes in dietary linoleic acid and its subsequent …

Crossing Borders In La Cocina: Constructing A Bilingual Community-Based Culinary Guide For A Healthier Tomorrow In Knoxville's Lonsdale Community, Erin M. Groh

Chancellor’s Honors Program Projects

No abstract provided.

Having An Elective Cesarean Section: Doing What's Best, Cynthia R Acuff Michaluk

Doctoral Dissertations

The purpose of this study was to discover a theory on how women decide to deliver their babies by cesarean section instead of experiencing a trial of labor and expected vaginal delivery when it is appropriate. The specific goals are to answer the research questions: What is the decision-making process by which healthy, low-risk women choose to deliver their babies by cesarean delivery in the absence of medical indications? What antecedents occur to influence a pregant woman's decision to undergo a maternal request cesaren section? Seven women from the surrounding Knoxville area underwent in-depth interviews. To qualify for the study, …

Proliferation Of Cross Border Trade In Health Services, Kevin Tolliver

Chancellor’s Honors Program Projects

No abstract provided.

When Swallowing Becomes Impossible, Jessica Dowdy

Chancellor’s Honors Program Projects

No abstract provided.

Une Étude Des Systèmes De Santé En France Et Aux États-Unis Et Des Leçons Que Les États-Unis Peuvent Tirer Du Système De Santé Français, Olivia A. Morin

Chancellor’s Honors Program Projects

No abstract provided.

The Effect Of Optimism On Determining Alpha Wave State, David James Dyrek

Chancellor’s Honors Program Projects

No abstract provided.

Omega-3 Polyunsaturated Fatty Acids: Methods To Reduce Atherosclerosis In The Obese Minipig, Mary E. Hall

Chancellor’s Honors Program Projects

No abstract provided.

Curricular Competencies Related To Cultural Competence For The Education And Training Of Registered Dietitians, Tegan Jean Medico

Masters Theses

Increasing demographic diversity, persistent health disparities, and ongoing efforts to reduce health care costs have made cultural and linguistic competence in the United States health care system a premier concern. Integral to improving cultural competence in health care is providing health professionals with adequate education and training in cultural competence. For this reason, there has been increasing attention paid by academia across health-related disciplines and by national organizations and governmental health agencies to delineating what cultural competence in education and training entails. Though a multidisciplinary body of literature on developing curricula related to cultural competence for health professionals exists, still …

"It's All About The Kids”: A Phenomenological Study Of The Experiences Of Special Needs Cheerleading Coaches, Kimberly Nichole Page

Masters Theses

p { margin-bottom: 0.08in; }a:link { color: rgb(0, 0, 255); Special needs sport literature is narrow-focused and generally focuses on the different disabilities of athletes (Howe & Jones, 2006). Additionally, cheerleading is generally researched in terms of disordered eating and body image (Thompson & Digsby, 2004), high injury risk (Jacobson, Hubbard & Redus, 2004; Jacobson, Redus, & Palmer, 2005), and over-sexualization of youth (Adams & Bettis, 2003). While several websites and resources for coaches of special needs athletes provide information for how a coach should feel, there is a lack of empirical research to support these claims (www.specialolympics.org; …

The Effect Of Midazolam On End-Tidal Concentration Of Isoflurane Necessary To Prevent Movements In Dogs, Reza Seddighi Dvm, Ms, Phd, Dip Acva

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Objective To determine the possible additive effect of midazolam, a GABAA agonist, on the end-tidal concentration of isoflurane that prevents movement (MACNM) in response to noxious stimulation. Study design Randomized crossover experimental study. Animals Six, healthy, adult intact male, mixed-breed dogs. Methods After baseline isoflurane MACNM (MACNM-B) determination, midazolam was administered as a low (LDS), medium (MDS) or high (HDS) dose series of midazolam. Each series consisted of two dose levels, low and high. The LDS was a loading dose (Ld) of 0.2 mg kg-1 and CRI (2.5 μg kg-1 minute-1) (LDL), followed by an Ld (0.4 mg kg-1) and …

Development Of A Mobile Teaching And Learning Module For Vm893 (Field Services) With, Brian K. Whitlock

Animal Science Publications and Other Works

The goal of this project is to develop a teaching and learning module with interactive comprehension assessments that can be used in a mobile (truck) or stationary (classroom) environment. A considerable portion of the Field Services clinical rotation is spent with students driving from the UT Veterinary Medical Center and from farm to farm in a large four-door truck. During these trips a consistent set of relevant topics will be delivered to students by discussing clinical cases. The format will be interactive and students will be equipped with technology allowing an assessment of their comprehension. Students will have day-to-day access …

The Spatial Epidemiology And Clinical Features Of Reported Cases Of La Crosse Virus Infection In West Virginia From 2003 To 2007, Andrew D. Haddow, Danae Bixler, Agricola Odoi

Entomology & Plant Pathology Publications and Other Works

Background

La Crosse virus (LACV) is a major cause of pediatric encephalitis in the United States. Since the mid-1980s, the number of reported cases of LACV infection in West Virginia has continued to rise and the state currently reports the most cases in the United States. The purpose of this study was to investigate and describe the spatial epidemiology and clinical presentation of LACV infection cases reported in West Virginia, as well as to provide a description of the environmental conditions present at the residences of the LACV infection cases.

Methods

Descriptive and spatial analyses were performed on LACV infection …

Protein C Activity In Dogs: Adaptation Of A Commercial Human Colorimetric Assay And Evaluation Of Effects Of Storage Time And Temperature, Michael M. Fry, Karl R. Snyder, Karen M. Tobias, Baye G. Williamson, Ann Reed

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Objectives of this study were to adapt a commercial human protein C (PC) colorimetric assay for use in dogs and to investigate effects of various storage conditions. The human assay was modified by using pooled canine plasma for calibration and by increasing the activation time. PC activity was measured in fresh canine plasma and in plasma stored under various conditions. PC activity of some stored samples was significantly different from that of fresh plasma; however, differences were small. No difference was detected in samples stored under similar conditions but analyzed in different laboratories using similar methodology. Results of this study …

Conceptual Debates And Empirical Evidence About The Peer Review Process For Scholarly Journals, Sandra Thomas

Faculty Publications and Other Works -- Nursing

No abstract provided.

Becoming An Older Volunteer: A Grounded Theory Study., J. W. Brown, S. L. Chen, Linda C. Mefford, A. Brown, B. Callen, P. Mcarthur

Faculty Publications and Other Works -- Nursing

This Grounded Theory study describes the process by which older persons “become” volunteers. Forty interviews of older persons who volunteered for Habitat for Humanity were subjected to secondary content analysis to uncover the process of “becoming” a volunteer. “Helping out” (core category) for older volunteers occurs within the context of “continuity”, “commitment” and “connection” which providemotivation for volunteering.When a need arises, older volunteers “help out” physically and financially as health and resources permit. Benefits described as “blessings” of volunteering become motivators for future volunteering. Findings suggest that older volunteering is a developmental process and learned behavior which should be fostered …

Faculty Scholarship Report - College Of Nursing - 2011, Center For Health Science Research

Nursing Annual Report of Scholarship

The 2011 Faculty Scholarship Report for the College of Nursing highlights the academic and research achievements of the University of Tennessee Nursing faculty during the 2010-2011 fiscal year.

2011 Faculty Scholarship Report - College Of Nursing, Center For Health Science Research

Center for Health Science Research Newsletter

The 2011 Faculty Scholarship Report for the College of Nursing highlights the academic and research achievements of the University of Tennessee Nursing faculty during the 2010-2011 fiscal year.