Medicine and Health Sciences Commons^™

Lighting Conditions And Optical Filters Effects On Visual Performance Of Speleologists Exposed To Cave Environments, Carla Costa Lança, Nádia Fernandes, Ana Monteiro, Ana Almeida

International Journal of Speleology

The aim of this study is to evaluate lighting conditions and speleologists’ visual performance using optical filters when exposed to the lighting conditions of cave environments. A cross-sectional study was conducted. Twenty-three speleologists were submitted to an evaluation of visual function in a clinical lab. An examination of visual acuity, contrast sensitivity, stereoacuity and flashlight illuminance levels was also performed in 16 of the 23 speleologists at two caves deprived of natural lightning. Two organic filters (450nm and 550nm) were used to compare visual function with and without filters. The mean age of the speleologists was 40.65 (± 10.93) years. …

Neurophysiological Activity Related To Speech Production: An Erp Investigation, Adithya Chandregowda

USF Tampa Graduate Theses and Dissertations

The event related potential (ERP) technique is enjoying widespread application in neurophysiological research due to its fine temporal resolution. Of relevance to this study are ERPs related to voluntary movements. The precision with which movement related processes could be recorded using the ERP technique was demonstrated by Gilden, Vaughan and Costa (1966) and Kutas and Donchin (1974, 1977, and 1980) who found that the readiness potential (RP) immediately preceding hand movement was larger over the hemisphere contralateral to the responding hand. Given that left hemisphere controls right hand movements and vice versa, their findings confirmed that the lateralized readiness potential …

Lipoproteins And Health Outcomes: Cognitive And Physical Function In Older Adults, Marianne Chanti-Ketterl

USF Tampa Graduate Theses and Dissertations

Cardiovascular health is a major determinant of quality of life and mortality, especially in older adulthood. With the world’s oldest population increasing at expedited rates, challenges from cardiovascular conditions and its implications are spawning. Although it is well known that dyslipidemia may lead to cardiac events, less is known about the effects on cognitive and physical function in older adults. Epidemiological studies show that optimizing current preventive strategies even at older ages may reduce the incidence of cardiovascular comorbidity (e.g. hypertension, stroke) and increase quality of life. Determining the association between lipoproteins and cognitive and functional performance in older adults …

Targeting Autopalmitoylation To Modulate Protein S-Palmitoylation, Laura Dawn Hamel

USF Tampa Graduate Theses and Dissertations

Palmitoylation refers to the covalent attachment of fatty acids, such as palmitate, onto the cysteine residues of proteins. This process may subsequently alter their localization and function. Nearly all of the enzymes that catalyze palmitoylation, zDHHC protein acyl transferases (PATs), are implicated in neurological disorders, infectious diseases, and cancer in humans. Of particular interest to those who study palmitoylation are Ras family GTPas and zDHHC9-GCP16, the zDHHC PAT that palmitoylates Ras proteins. Erf2-Erf4 is the zDHHC PAT that palmitoylates Ras proteins in Saccharomyces cerevisiae. Currently, there are no methods to therapeutically target palmitoylation for the treatment of disease. One …

Molecular And Phenotypic Studies Validating The Role Of The Ecdysone Receptor In The Human Parasite Brugia Malayi, Amruta Mhashilkar

USF Tampa Graduate Theses and Dissertations

Filariasis and onchocerciasis are debilitating diseases affecting 120 million people globally. The massive socio-economic impact of these diseases energized the international community to declare a goal of eliminating filariasis 2020. This resulted in a dramatic increase in the efforts to eliminate filariasis and onchocerciasis, employing a strategy of mass drug administration (MDA). However, these programs rely upon the small arsenal of drugs. This leaves these programs vulnerable to failure in the face of developing resistance and local intolerance to the current drug regimens. Thus, new drugs against these infections are critically needed. A homologue of the ecdysone receptor (EcR), a …

Use Of Spirometry For Medical Clearance And Surveillance In Occupations Requiring Respirator Use, Ushang Prakshbhai Desai

USF Tampa Graduate Theses and Dissertations

Medical certification of workers for respirator use is an important activity of occupational medicine health professionals. Spirometry is a diagnostic tool to evaluate respiratory distress/insufficiency that may affect respirator use. In this study, we analyzed the pulmonary function data of 337 workers from different occupations which required medical evaluation to wear a respirator. The American Thoracic Society and National Fire Protection Association criteria were used to evaluate employees. Of 337 workers who were cleared for respiratory use on the basis of medical questionnaires for respirator compliance, 14 (4.15%) failed to pass respirator compliance on the basis of NFPA criteria and …

Cognitive Load Of Registered Nurses During Medication Administration, Sarah Faith Perron

USF Tampa Graduate Theses and Dissertations

Over 4 million avoidable hospital admissions result from medication errors (IMS Insitute for Healthcare Informatics, 2013). Human error accounts for 80% of all medical errors (Palmieri, DeLucia, Peterson, Ott, & Green, 2008). Medication administration is a complex process. It is important to understand the cognitive load (CL) of Registered Nurses (RNs) working in an electronic health record environment to identify the risk factors of medication errors. The purpose of this study is to investigate the factors that influence the CL of RNs during medication administration who are working in an electronic health record environment. Simulated medication administration scenarios with varying …

Estimating Likelihood Of Having A Brca Gene Mutation Based On Family History Of Cancers And Recommending Optimized Cancer Preventive Actions, Mehrnaz Abdollahian

USF Tampa Graduate Theses and Dissertations

BRCA1 and BRCA2 are gene mutations that drastically increase chances of developing breast and ovarian cancers, up to 20-fold, for women. A genetic blood test is used to detect BRCA mutations. Though these mutations occur in one of every 400 in the general population (excluding Ashkenazi Jewish ethnicity), they are present in most cases of hereditary breast and ovarian cancer patients. Hence, it is common practice for the physicians to require genetic testing for those that fit the rules as recommended by the National Cancer Comprehensive Network. However, data from the Myriad Laboratory, the only provider of the test until …

An Animal Model Of Flashbulb Memory: Insights Into The Time-Dependent Mechanisms Of Memory Enhancement, Laura Ashley Bullard

USF Tampa Graduate Theses and Dissertations

The vivid memory of an emotional event, as well as memory for incidental details associated with the arousing event, has been referred to collectively as a “flashbulb memory”. An important aspect of flashbulb memory in people is that an emotional event enhances memory of contextual details, such as the weather, or clothes one was wearing at the time of the event. Therefore, an emotional event not only produces a detailed memory of the event, itself, but also enhances memory for contextual details that would otherwise not be remembered. The first goal of this work is to describe the development of …

Understanding How Young People Experience Risk With Online-To-Offline Sexual Encounters: A Second Qualitative Phase For The Ch@T Project, Elizabeth Vp Marwah

USF Tampa Graduate Theses and Dissertations

This study investigates how heterosexual young people understand and manage risks related to meeting sexual partners online in the United States. The purpose of this study is to help inform the development of culturally-appropriate sexual risk communication and health promotion messages for young people by linking public health knowledge of adolescent sexual health and eHealth with anthropological theories of risk. With qualitative data from two rounds of semi-structured interviews and two group interviews with university students in central Florida, this study shows how young people experience and prioritize more social-emotional risks in meeting online-to-offline sexual partners compared to physical risks. …

Characterization Of Noise Exposure For High-Volume Restaurant Workers, Desiree Gladieux

USF Tampa Graduate Theses and Dissertations

Occupational hearing loss resulting from noise exposures encountered in the workplace affects millions of workers and costs hundreds of millions of dollars annually in Workers’ Compensation costs in the United States alone. Some industries have been well studied, and the presence of hazardous noise in the work environment established and documented. The restaurant industry is one in which little current data exists, but in which there may be cause for concern.

This work sought to quantify noise exposures for cooks, servers, and dishwashers and to determine whether or not any of these workers are at risk for Noise Induced Hearing …

Factors Associated With Treatment Seeking In Automotive Manufacturing, Khin Thingyan Chit

USF Tampa Graduate Theses and Dissertations

Introduction

The prevalence of work-related musculoskeletal disorders is very common. The main objective of the study was to identify any association between the severity of musculoskeletal symptoms and treatment choice by workers in automobile manufacturing plants.

Methods

A cross-sectional study of 1017 production workers in six automobile manufacturing plants was performed. The study included the structured interviews to determine symptoms, preexisting personal risk factors, treatment choices (health care provider or no treatment sought), job strain, and job satisfaction. Nordic style questionnaire for symptoms, Karasek’s Demand Control Model and three job satisfaction questions were used to assign symptom severity, job strain, …

Basal Salivary Oxytocin And Skin To Skin Contact Among Lactating Mothers Of Premature Infants, Jessica Marie Gordon

USF Tampa Graduate Theses and Dissertations

This dissertation research explored mechanisms of human milk (HM) expulsion by describing the effects of skin to skin contact (SSC) on maternal basal oxytocin (OT) secretion among 20 premature mothers with hospitalized premature infants. This one-group, repeated measures design consisted of: 1) daily SSC with covariant data via self-report diary and 2) maternal salivary OT with and without SSC at 4 time points were collected over a 7 day time frame. Results indicate that mean levels of basal OT increase over time (M 234 pg/ml, SD 108 pg/ml time point 1; M 257 pg/ml, SD 125 pg/ml time point 3). …

Implementation Of Medicaid Managed Long-Term Services And Supports For Adults With Intellectual And/Or Developmental Disabilities: A State’S Experience, Heather Jeanne Williamson

USF Tampa Graduate Theses and Dissertations

Background: Individuals with intellectual and/or developmental disabilities (IDD) are experiencing longer life expectancies with the majority requiring the ongoing support of family caregivers into adulthood. Medicaid is the primary funding source for supports and services for adults with IDD. Growing Medicaid expenditures and goals to improve quality of care are driving more states to move their Medicaid fee-for-service programs into a managed care model. The stated goals of Medicaid managed long-term services and supports (MLTSS) are to improve care coordination and access to care while controlling costs, but the evidence regarding these outcomes is limited and mixed. Given the level …

The Concept Of Missing Incidents In Persons With Dementia, Meredeth Rowe, Amy M. Houston, Victor A. Molinari, Tatjana Bulat, Mary E. Bowen, Heather Spring, Sandra Mutolo, Barbara Mckenzie

Nursing Faculty Publications

Behavioral symptoms of dementia often present the greatest challenge for informal caregivers. One behavior, that is a constant concern for caregivers, is the person with dementia leaving a designated area such that their whereabouts become unknown to the caregiver or a missing incident. Based on an extensive literature review and published findings of their own research, members of the International Consortium on Wandering and Missing Incidents constructed a preliminary missing incidents model. Examining the evidence base, specific factors within each category of the model were further described, reviewed and modified until consensus was reached regarding the final model. The model …

Applying Voronoi Tessellations As A Non-Orthogonal Grid Methodology To Inform Public-Private Mix Efforts In Nigeria: An Examination Of The Distribution Of Private Healthcare Providers In Six States And The Covariates Underlying Their Utilization, Trinadh Dontamsetti

USF Tampa Graduate Theses and Dissertations

TB care and prevention is led by the public sector, but many TB symptomatics first seek care in the private sector, highlighting the importance of engaging these facilities. This report examines basic TB epidemiology (such as the gap in case finding that could be addressed in part via private sector activities), health-seeking behaviors (HSB) and diagnostic delays, the size of the private sector, activities of professional societies, and financing. It examines the potential utility of integrating Voronoi tessellations as a GIS-based method for informing and improving Public-Private Mix (PPM) efforts throughout six states in Nigeria. Further, it explores a potential …

The Influence Of Relationship Status On Hpv Vaccine Decision-Making Among Young Adult Women, Erika L. Thompson

USF Tampa Graduate Theses and Dissertations

Background: The HPV vaccine is a primary prevention method available to reduce the burden of HPV-related cancers and genital warts. The vaccine is currently approved for catch-up vaccination among women 18 to 26 years of age. Despite this recommendation, the rate of vaccine uptake among this group is considerably low (~34% uptake). One demographic characteristic that is consistently reported as a risk factor for non-vaccination is relationship status, specifically married or monogamous relationships. While the epidemiological data confirm this association, there is a lack of understanding how this risk factor operates. By elucidating the mechanism for this risk factor, …

Informing The Design And Deployment Of Health Information Technology To Improve Care Coordination, Diego A. Martinez

USF Tampa Graduate Theses and Dissertations

In the United States, the health care sector is 20 years behind in the use of information technology to improve the process of health care delivery as compared to other sectors. Patients have to deliver their data over and over again to every health professional they see. Most health care facilities act as data repositories with limited capabilities of data analysis or data exchange. A remaining challenge is, how do we encourage the use of IT in the health care sector that will improve care coordination, save lives, make patients more involved in decision-making, and save money for the American …

Structure Based Drug Design Targeting Bacterial Antibiotic Resistance And Alzheimer's Disease, Eric Michael Lewandowski

USF Tampa Graduate Theses and Dissertations

Structure based drug design is a rapidly advancing discipline that examines how protein targets structurally interact with small molecules, or known inhibitors, and then uses this information to lead inhibitor optimization efforts. In the case of novel inhibitors, protein structural information is first obtained via X-ray crystallography, NMR studies, or a combination of both approaches. Then, computational molecular docking is often used to screen, in silico, millions of small molecules and calculate the potential interactions they may have with the target protein’s binding pocket, in hopes of identifying novel low affinity inhibitors. By examining the interactions these small, low affinity, …

Role Of The Slingshot-Cofilin And Ranbp9 Pathways In Alzheimer's Disease Pathogenesis, Jung A Woo

USF Tampa Graduate Theses and Dissertations

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by two major pathological hallmarks, amyloid plaques and neurofibrillary tangles. The accumulation of amyloid-β protein (Aβ) is an early event associated with synaptic and mitochondrial damage in AD. Therefore, molecular pathways underlying the neurotoxicity and generation of Aβ represent promising therapeutic targets for AD. Recent studies have shown that actin severing protein, Cofilin plays an important role in synaptic remodeling, mitochondrial dysfunction, and AD pathogenesis. However, whether Cofilin is an essential component of AD pathogenesis and how Aβ induced neurotoxicity impinges its signals to Cofilin are unclear.

In my dissertation studies, we …

“Principal Component Analysis And The Cumulative Gait Index: Translational Tools To Assess Gait Impairments In Rats With Olivocerebellar Ataxia”, Chase Lambert

USF Tampa Graduate Theses and Dissertations

Numerous studies suggest that modulation of the cholinergic system through the use of nicotinic agonists can improve motor function in humans or animals with motor disorders. Specifically, although there are no approved therapeutics for patients with ataxia, the nicotinic receptor agonist varenicline has demonstrated efficacy to improve coordination and gait in several groups of patients with different subtypes of ataxia. Importantly, the mechanism underlying the varenicline’s mechanism of action to improve motor function remains to be elucidated. Thus, the purpose of these experiments was to first quantify gait impairments in rats with olivocerebellar ataxia utilizing an objective treadmill-based system to …

Enc 2210 Technical Writing For Health Science, Johanna Hillen

Service-Learning Syllabi

No abstract provided.

The Effects Of Parent-Adolescent Communication And Parenting Style On The Physical Activity And Dietary Behaviors Of Latino Adolescents, Dianna Mary Boone

USF Tampa Graduate Theses and Dissertations

The obesity epidemic among children and adolescents has been growing rapidly over the past 10 years, particularly in Latino children. Multiple researchers have found support for positive associations between parent-child communication and healthy nutrition and exercise behaviors. The present study examined the relations between parent-adolescent communication and parenting style and the dietary and exercise behaviors of Latino adolescents. The study included 79 adolescents between the ages of 13 and 18 years and their parents (100% are Latino). Correlation and hierarchical regression analyses were conducted to determine which parenting style and communication variables are significantly associated with adolescents’ dietary and physical …

The Durational Effects Of A Free Operant Condition On Automatically Maintained Stereotypic Behavior And Discrete Trial Task Responding, Shikika Sade Young

USF Tampa Graduate Theses and Dissertations

This study examined the effects of three fixed-duration free operant access conditions on rates of automatically maintained stereotypic behavior and correct task responding during discrete trial training (DTT) with two children diagnosed with autism. Following a functional analysis, confirming automatic function, interviews/observations were conducted to identify behavioral indicators of satiation and an average satiation level. In this endeavor, participants were exposed to a free operant condition to validate satiation of stereotypic responding. Once satiation level was averaged, two durational conditions were computed: Long (75% access) and Short (25% access). A third condition, Deprivation, involved blocking all attempts at the stereotypic …

Assessing The Occupational Nosie Exposure Of Bartenders, Adrianna J. Woltman

USF Tampa Graduate Theses and Dissertations

The Occupational Safety and Health Administration estimates that each year, approximately 30 million people are occupationally exposed to hazardous noise. While many are aware of the noise exposure associated with industrial occupations, there has been little research conducted on bartenders who often work in environments that have high levels of noise. The majority of current published research on occupational noise exposure of bartenders has only evaluated noise levels on one night of business. Bartenders often work multiple days per week, which vary in the amount of patrons and entertainment provided, this variation in business leads to variation in the amount …

Rape, Race, And Capital Punishment In North Carolina: A Qualitative Approach To Examining An Enduring Cultural Legacy, Douglas Wholl

USF Tampa Graduate Theses and Dissertations

Despite positive steps toward the suppression of racial discrimination in the United States capital punishment process, the enduring effects of a cultural legacy of Black oppression (e.g., slavery; segregation; lynching) and historic and systemic racial discrimination in the criminal justice system have persisted to the present day. The purpose of the current study is to explore whether this enduring cultural legacy still exists by examining whether juries in rape-involved capital murder trials in North Carolina are more likely to recommend a sentence of death when the defendant is a Black male and the victim is a White female (compared to …

Evaluation Of Soil As A Risk Indicator For Human Leptospirosis In Coastal, Rural Ecuador, Chad Allen Weddell

USF Tampa Graduate Theses and Dissertations

Leptospirosis, a zoonotic disease caused by pathogenic spirochete bacteria (family Leptospiraceae, genus Leptospira), is endemic in developing tropical regions of the world. It occurs in epidemics and is endemic in Ecuador where environmental conditions are ideal for maintenance. The role of soil as a long term reservoir has been previously been documented. Geographic Information System (GIS) and Remote Sensing (RS) technology was used in our study to further explore the role of soil as an environmental reservoir and its potential use as a static risk indicator for disease. Red, Green, Blue (RGB) spectral band data from known leptospire …

A Socio-Ecological Model Of Affordable Care Act Acceptance, Pratiksha Vaghela

USF Tampa Graduate Theses and Dissertations

Background: Since 1965, there have not been any major revisions of the healthcare laws in the United States, until the recent implementation of the Affordable Care Act (ACA). However, ACA is not well understood and is often controversial. The purpose of this study is to: (1) evaluate the relationship between the employers’ and the employees’ perceptions regarding the ACA mandates for small businesses, (2) evaluate the relationship between the self-reported and the tested knowledge of individuals regarding the ACA mandates for small businesses, and (3) determine if socio-demographic factors influence individual’s perception of the law. Based on the gathered information, …

A Comparison Of Quality Of Life Between Intense And Non-Intense Treatment For Patients With Acute Myeloid Leukemia And High-Risk Myelodysplastic Syndrome, Sara Marie Tinsley

USF Tampa Graduate Theses and Dissertations

Acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) are hematologic malignancies that occur most frequently in the sixth and seventh decades of life. Both disorders are associated with a poor prognosis, with median survival of one year or less. An overall five-year survival rate for both disorders, regardless of treatment, is less than 10%. A primary goal of treatment is to improve quality of life (QOL) because cure is improbable. The purpose of this longitudinal cohort study was to compare QOL between groups, intensive, non-intensive therapy, and supportive care. The sample consisted of 85 patients with high risk MDS …

A Community Of Isolation: An Ethnographic Examination Of Mothering In Poverty And Its Impact On Food Security In Pinellas County, Florida, Amanda M. Terry

USF Tampa Graduate Theses and Dissertations

The objective of this dissertation is to document the lived experience of mothering in poverty and the unique challenges the role of mother presents to maintaining food security. Millions of households in the United States are struggling to put food on the table, a problem made worse by the current economic recession and high food prices. Among them, households with children and specifically, single mothers, report the highest prevalence of food insecurity. While Federal food assistance programs are available to help alleviate this issue, the continued problem of hunger is a very real and pervasive concern for millions of American …