Medicine and Health Sciences Commons^™

The Safety And Efficacy Of Physical Agents On Cancer Survivors: An Update, Katelyn Ratliff Spt, Gentry Ensign Spt, Kathryn Flyte Spt, Michael Moore Spt, Ann Wilson Pt, M.Ed., Gcs

Physical Therapy Research Symposium

Title: The Safety and Efficacy of Physical Agents on Cancer Survivors: An Update

Authors: Gentry Ensign, SPT¹; Kathryn Flyte, SPT¹; Michael Moore, SPT¹; Katelyn Ratliff, SPT¹; Ann Wilson, P.T., M.Ed., GCS¹

Affiliations: 1. School of Physical Therapy, University of Puget Sound

Theory: Cancer patients are often referred to physical therapy to treat impairments associated with cancer, its treatment, and the disease progression. Physical therapists sometimes use physical agents as part of a complete rehabilitation program for the purpose of decreasing pain, increasing strength, and facilitating tissue healing while avoiding possible malignant …

Rok And Rac Mediation Of Prl-1 Function In The Wings Of Drosophila Melanogaster, Rosemary Dinkins

Honors Program Theses

By the time a cancer metastasizes it has reached its most deadly stage. It therefore is essential that the underpinning mechanisms promoting metastasis are understood. Phosphatases of regenerating liver (PRL) have been repeatedly connected to cancer metastasis when overexpressed. However, little is yet known about the normal PRL function and biological pathways let alone the PRL pathway promoting metastasis. The current study explores the relationship between PRL-1 and two other genes, ROK and Rac,that have also been implicated in cell migration and metastasis. Increased PRL-1 function in conjunction with increased or decreased Rac function was forced to the dorsal half …

Prl-1’S Inhibition Of Drosophila Melanogaster Cell Growth Is Dependent On The Caax Membrane Localization Domain, Bryce Bunn

Summer Research

The human body exhibits a spectacular collection of cells, integrated with seemingly infinite communication techniques and control mechanisms. Cancer’s disastrous influence on this complex system proves difficult to map. The shotgun clinical trial testing of human cancers has provided a feast of proteins suspected of encouraging cancerous cell behavior. One, Phosphatase of Regenerating Liver protein-1 (PRL-1), has been found to encourage cancerous growth while localizing in a variety of subcellular locations within metastasizing human tumor cells. However, PRL-1 has also been found to act as a tumor suppressor while localizing to the cell membrane in mammalian and insect models. In …