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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
Impaired Fast-Spiking, Suppressed Cortical Inhibition, And Increased Susceptibility To Seizures In Mice Lacking Kv3.2 K+ Channel Proteins, David Lau, Eleazar Vega-Saenz De Miera, Diego Contreras, Alan Chow, Richard Paylor, Christopher S. Leonard, Bernardo Rudy
Impaired Fast-Spiking, Suppressed Cortical Inhibition, And Increased Susceptibility To Seizures In Mice Lacking Kv3.2 K+ Channel Proteins, David Lau, Eleazar Vega-Saenz De Miera, Diego Contreras, Alan Chow, Richard Paylor, Christopher S. Leonard, Bernardo Rudy
NYMC Faculty Publications
Voltage-gated K(+) channels of the Kv3 subfamily have unusual electrophysiological properties, including activation at very depolarized voltages (positive to -10 mV) and very fast deactivation rates, suggesting special roles in neuronal excitability. In the brain, Kv3 channels are prominently expressed in select neuronal populations, which include fast-spiking (FS) GABAergic interneurons of the neocortex, hippocampus, and caudate, as well as other high-frequency firing neurons. Although evidence points to a key role in high-frequency firing, a definitive understanding of the function of these channels has been hampered by a lack of selective pharmacological tools. We therefore generated mouse lines in which one …
Chironian Fall/Winter 2000, New York Medical College
Chironian Fall/Winter 2000, New York Medical College
The Chironian
No abstract provided.
Chironian Spring/Summer 2000, New York Medical College
Chironian Spring/Summer 2000, New York Medical College
The Chironian
No abstract provided.
1997 - 2000 Touro University College Of Osteopathic Medicine Yearbook, Touro University College Of Osteopathic Medicine
1997 - 2000 Touro University College Of Osteopathic Medicine Yearbook, Touro University College Of Osteopathic Medicine
Yearbooks and Newsletters
1997 - 2000 Touro University College of Osteopathic Medicine Yearbook.