Medicine and Health Sciences Commons^™

Bridging Conflicting Ideologies: The Origins Of American And British Occupational Therapy., Ruth L. Schemm

Department of Occupational Therapy Faculty Papers

Occupational therapy practice has bridged two contradictory value systems for more than 100 years. This article describes the origins of practice ideas in both the United States and Britain and demonstrates that founding members of the occupational therapy profession all shared a core of humanistic beliefs while embracing the emerging paradigm of scientific medicine. The result has been an intellectual tension between the biological and the psychosocial aspects of practice. For more than 75 years, occupational therapists struggled to balance the art and science of patient care; recent debates on modalities, practice domains, and research priorities indicate that the unifying …

Nurses Alumni Association Bulletin, Fall 1994, Alice C. Boehret, Nancy E. Powell, Pamela G. Watson, Betty Piersol, Margaret Summers, Mildred Greenlee Durham, Dorothy Ranck Long, Jane Dietrich, Paula J. Levine, Doris E. Bowman, Lorraine Mccall

Nursing Alumni Bulletins

1994-1995 Meeting Dates Calendar

1995 Annual Luncheon - Meeting Notice

Officers and Committee Chairs

Bulletin Publication Committee

1994-1995 Meeting Dates Calendar

The President's Message

Treasurer's Report

News About Our Graduates

Fiftieth Anniversary

Resume of Minutes of Alumni Association Meetings

Department of Nursing 1993-1994

Alumni Office News

Jefferson 2000 Fund

The Women's Center for Health Promotion

Discount Parking for Alumni

Cadet Nurse Corps

Medical Anecdotes of Faith

Ukranian-American Teacher Exchange

Happy Birthday

Committee Reports

In Memoriam, Names of Deceased Graduates

Luncheon Photos

Class News

Jefferson Alumni Identification Card

Relief Fund Application

Scholarship Application

Membership Application

Pins, Transcripts, Class Address Lists, Change …

Jefferson Alumni Bulletin – Volume Xliii, Number 3, Fall 1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 3, Fall 1994 Diary of an SCI, page 5 Colleagues honor Cotler with portrait, page 7 Neurosensory institute is established, department of neurosurgery expands, page 7 Teaching molecular medicine, preparing for practice in the 21st Century, page 8 On campus, page 11 Jefferson Research, page 12 Giving to Jefferson, page 14 Obituaries, page 16 Class notes, page 18

Epidermal Growth Factor Coordinately Regulates The Expression Of Prostaglandin G/H Synthase And Cytosolic Phospholipase A2 Genes In Embryonic Mouse Cells., Kenneth P. Chepenik, Arturo Diaz, Sergio A. Jimenez

Department of Medicine Faculty Papers

Confluent, primary cultures of mouse embryo palate mesenchyme (MEPM) cells are refractory to activation of phospholipase A2 (PLA2) by the calcium ionophore A23187. However, treatment of these cultures with epidermal growth factor (EGF) permits the cells to activate PLA2 in response to A23187. We have developed this finding by exploring molecular mechanisms by which growth factors modulate mobilization and metabolism of arachidonic acid. We found chronic treatment (> 6 h) of confluent MEPM cells with EGF (a) increases their ability to metabolize exogenous arachidonic acid to prostaglandin E2 (PGE2) and (b) stimulated constitutive expression of activities of PLA2 and cyclooxygenase …

A Randomized Comparison Of Coronary-Stent Placement And Balloon Angioplasty In The Treatment Of Coronary Artery Disease. Stent Restenosis Study Investigators., David L. Fischman, Martin B. Leon, Donald S. Baim, Richard A. Schatz, Michael P. Savage, Ian Penn, Katherine Detre, Lisa Veltri, Donald Ricci, Masakiyo Nobuyoshi, Michael Cleman, Richard Heuser, David Almond, Paul S. Teirstein, R. David Fish, Antonio Colombo, Jeffrey Brinker, Jeffrey Moses, Alex Shaknovich, John Hirshfeld, Stephen Bailey, Stephen Ellis, Randal Rake, Sheldon Goldberg

Department of Medicine Faculty Papers

BACKGROUND: Coronary-stent placement is a new technique in which a balloon-expandable, stainless-steel, slotted tube is implanted at the site of a coronary stenosis. The purpose of this study was to compare the effects of stent placement and standard balloon angioplasty on angiographically detected restenosis and clinical outcomes.

METHODS: We randomly assigned 410 patients with symptomatic coronary disease to elective placement of a Palmaz-Schatz stent or to standard balloon angioplasty. Coronary angiography was performed at base line, immediately after the procedure, and six months later.

RESULTS: The patients who underwent stenting had a higher rate of procedural success than those who …

Molecular Cloning And Expression Of A Unique Receptor-Like Protein-Tyrosine-Phosphatase In The Leucocyte-Common-Antigen-Related Phosphatase Family, Wei-Ren Zhang, Naotake Hashimoto, Faiyaz Ahmad, Wendi Ding, Barry J. Goldstein

Department of Medicine Faculty Papers

Protein-tyrosine-phosphatases (PTPases) have been implicated in the regulation of certain tyrosine kinase growth factor receptors in that they dephosphorylate the activated (autophosphorylated) form of the receptors. In order to identify PTPases that potentially act on receptor targets in liver, we used the human leucocyte common antigen-related PTPase (LAR) cDNA [Streuli, Krueger, Hall, Schlossman and Saito (1988) J. Exp. Med. 168, 1523-1530] and isolated two closely related transmembrane PTPase homologues from a rat hepatic cDNA library. Both PTPases had large extracellular domains that contained three immunoglobulin-like repeats and eight type-III fibronectin repeats. Both enzymes had tandem homologous PTPase domains following a …

Jefferson Alumni Bulletin – Volume Xliii, Number 4, Summer 1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 4, Summer 1994

The social transformation of practice, page 8

How medicine is taught differently now, page 8

The only constant is change, page 8

Medicine is being challenged and physicians must respond, page 8

Vascular Ectasias of the colon, page 9

Jefferson and AIDS care in Uganda, page 10

Laparoscopic cholecystectomy at Pennsylvania hospital, page 10

Nintendo comes to medicine: 3-D MRI of congenital heart disease, page 11

Imaging of psychiatric conditions, page 12

Effects of space flight on human physiology: A Jefferson Study, page 12

Aesthetic considerations after trauma, page 13 …

Department Of Radiology-Annual Report-July 1, 1993 To June 30, 1994, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1993 to June 30, 1994. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 107 pages.

The Board Of Trustees: An Indispensable Asset, Frederick B. Wagner, Jr.

Jefferson History Books

A history of Thomas Jefferson University's Board of Trustees, from 1826-1994.

Functional Analysis Of Human Alpha 1(I) Procollagen Gene Promoter. Differential Activity In Collagen-Producing And -Nonproducing Cells And Response To Transforming Growth Factor Beta 1., Sergio A. Jimenez, John A. Varga, Anne Olsen, Liye Li, Arturo Diaz, Janet Herhal, Julie Koch

Department of Medicine Faculty Papers

To gain a further understanding of the regulation of human type I collagen gene expression under physiologic and pathologic conditions, we characterized 5.3 kilobase pairs (kb) of the human alpha 1(I) procollagen gene promoter. A series of deletion constructs containing portions of the alpha 1(I) procollagen 5'-flanking region (with end points from -5.3 kb to -84 base pairs (bp)) ligated to the chloramphenicol acetyltransferase (CAT) reporter gene were transiently transfected into NIH/3T3 cells. Maximal CAT activity was observed with constructs having 5' end points from -804 to -174 bp. A further 5' deletion to -84 bp caused a marked reduction …

Elevated Expression Of Type Vii Collagen In The Skin Of Patients With Systemic Sclerosis. Regulation By Transforming Growth Factor-Beta., Lidia Rudnicka, John Varga, Angela M. Christiano, Renato V. Iozzo, Sergio A. Jimenez, Jouni Uitto

Department of Dermatology and Cutaneous Biology Faculty Papers

A hallmark of systemic sclerosis (SSc) is the development of tissue fibrosis. Excessive production of several connective tissue components normally present in the dermis, including type I, III, V, and VI collagens as well as fibronectin and proteoglycans, is a consistent finding in the skin of SSc patients. Type VII collagen is a major constituent of anchoring fibrils, present in the skin at the dermal-epidermal basement membrane zone. TGF-beta has been shown to upregulate the expression of the type VII collagen gene. In this study, we assessed the expression of type VII collagen and TGF-beta in the skin of patients …

Jefferson Alumni Bulletin – Volume Xliii, Number 3, Spring 1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 3, Spring 1994

Anesthesiology is never at rest, page 2

The medical college’s past ten years and its future, page 8

New health care climate, page 13

Student life, page 15

Books, page 14

Albuterol may increase the effectiveness of Parkinson’s disease therapy, page 16

NIH Continues support for scleroderma research, page 16

Faculty number among area’s most cited scientists, page 16

On campus, page 16

Class notes, page 22

Management Decisions Made By Caregiver Spouses Of Persons With Alzheimer's Disease., Mary A. Corcoran

Department of Occupational Therapy Faculty Papers

OBJECTIVES: As the incidence of Alzheimer's disease increases, so does the effect on families and friends who assume caregiving responsibilities. Despite the proliferation of caregiving studies reported in the literature, little is known of the day-to-day management styles and preferences of caregivers. To develop, implement, and test interventions designed to sustain caregivers in their role, more information is needed about the caregiving experience. Results of a descriptive study are presented as a first step in understanding the complex process of choosing, organizing, and implementing everyday caregiving tasks.

METHOD: Subjects of the study were 26 persons who provide care for a …

Jefferson Alumni Bulletin – Volume Xliii, Number 2, Winter 1993-1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 2, Winter 1993-1994

Strong surgical staff broadens research, page 3

PHO will merge the faculty and the hospital into one legal entity, page 8

How health care reform may impact teaching and research, page 8

M.D. /M.B.A. and M.D. /M.H.A. will be offered, page 8

Jefferson will work closely with Pennsylvania hospital, page 9

Someone will chair neurosurgery, page 9

On campus, page 11

Research, page 12

Chemotherapy prior to surgery helps at stage III, page 12

Lumpectomy combined with radiation implants, page 12

Elections/Appointments, page 14

Class notes, page 21