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Raman Microspectroscopy For The Discrimination Of Thyroid And Lung Cancer Subtypes For Application In Clinical Cytopathology, Declan O'Dea

Doctoral

The branch of cytology known as cytopathology, studies and diagnoses diseases at a cellular level, and is a useful method for detecting cancer. The procedures used to attain cytological samples for diagnostic purposes, such as aspiration and exfoliative methods are safe, accurate and cost-effective. Histochemical and immunohistochemical (IHC) techniques are commonly applied to cytological samples to aid cancer diagnosis, however multiple limitations occur using these methods for the diagnosis of thyroid cancer (TC) and non-small cell lung cancer (NSCLC). Fine needle aspiration cytology (FNAC) is the prominent diagnostic method used for the initial investigation of thyroid nodules but is limited …