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A Comparative Study Of Preoperative Versus Intraoperative Meperidine Administration In Patients Receiving General Anesthesia: A Prospective, Randomized Double-Blind Study, Hüseyi̇n Sert, Rüveyda İrem Demi̇rci̇oğlu, Burhanetti̇n Usta, Bünyami̇n Muslu, Ümmügülsüm Yazici, Muhammet Gözdemi̇r, Önder Sürgi̇t

Turkish Journal of Medical Sciences

To evaluate the effects of preoperative and intraoperative administration of intravenous meperidine as a preemptive analgesic. Materials and methods: A total of 50 patients were randomly divided into 2 groups; group P received 1 mg/kg of meperidine intravenously immediately before induction of anesthesia, and group I received the same amount of meperidine 20 min before completion of surgery. Consumption of desflurane, recovery parameters, heart rate, mean arterial pressure, sedation scores, visual analog scale (VAS) scores for pain, analgesic needs, and anesthesia-related complications were recorded for both groups. Results: Time to recovery was significantly shorter in group P than in group …