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Full-Text Articles in Medicine and Health Sciences

Investigation Of Stilbenoids As Potential Therapeutic Agents For Rotavirus Gastroenteritis, Judith M. Ball, Fabricio Medina-Bolivar, Katelyn D. Defrates, Emily Hambleton, Megan E. Hurlburt, Lingling Fang, Tianhong Yang, Luis Nopo-Olazabal, Richard L. Atwill, Pooj Ghai, Rebecca D. Parr Aug 2015

Investigation Of Stilbenoids As Potential Therapeutic Agents For Rotavirus Gastroenteritis, Judith M. Ball, Fabricio Medina-Bolivar, Katelyn D. Defrates, Emily Hambleton, Megan E. Hurlburt, Lingling Fang, Tianhong Yang, Luis Nopo-Olazabal, Richard L. Atwill, Pooj Ghai, Rebecca D. Parr

Faculty Publications

Rotavirus (RV) infections cause severe diarrhea in infants and young children worldwide. Vaccines are available but cost prohibitive for many countries and only reduce severe symptoms. Vaccinated infants continue to shed infectious particles, and studies show decreased efficacy of the RV vaccines in tropical and subtropical countries where they are needed most. Continuing surveillance for new RV strains, assessment of vaccine efficacy, and development of cost effective antiviral drugs remain an important aspect of RV studies. This study was to determine the efficacy of antioxidant and anti-inflammatory stilbenoids to inhibit RV replication. Peanut (A. hypogaea) hairy root cultures were induced …


Teaching Body Awareness To Students With Visual Impairments And Additional Disabilities, Vicki Depountis, Phoebe Okungu, Tracy Hallak, Jennifer Taylor Apr 2015

Teaching Body Awareness To Students With Visual Impairments And Additional Disabilities, Vicki Depountis, Phoebe Okungu, Tracy Hallak, Jennifer Taylor

Bright Ideas Conference

Body awareness, spatial awareness, and positional language, are essential elements of orientation and mobility (O&M). Typically developing students usually learn these concepts and skills incidentally as they interact with various environments. Students with visual impairments and/or multiple disabilities must be deliberately taught these concepts using research-based strategies. Routine-based learning, integration of music, picture and tactile communication, and physical and verbal guidance have been shown to enhance learning by students with visual impairments and/or multiple disabilities. When these strategies are incorporated into individually designed structured movement routines (SMRs), students are more likely to anticipate movements and connect language to corresponding O&M …


Optimization Of Fluorescent Detection Of Rotavirus Protein Nsp4 And A Cellular Receptor In Two Cell Lines, Katelyn D. Defrates, Rebecca Walker, Ron Havenar, Rebecca D. Parr Apr 2015

Optimization Of Fluorescent Detection Of Rotavirus Protein Nsp4 And A Cellular Receptor In Two Cell Lines, Katelyn D. Defrates, Rebecca Walker, Ron Havenar, Rebecca D. Parr

Bright Ideas Conference

Rotavirus (RV) infections are the most common cause of severe diarrhea in infants and young children worldwide. The two licensed vaccines for RV protect children from common strains of RV, but they are less effective against new emerging RV strains. Therefore, new therapeutics to treat RV infections need to be developed. Recently, we have shown stilbenoids, trans-arachidin-1 (t-A1) and trans-arachidin-3 (t-A3), decrease progeny virus particles by one hundred fold. Likewise, western blot assays show a decrease in the amount of the viral protein NSP4 with the addition of the stilbenoids during a RV infection. This indicates an effect on viral …


Treating Test Anxiety With Diffused Aromatherapy, Carol Athey, Joanie Selman Apr 2015

Treating Test Anxiety With Diffused Aromatherapy, Carol Athey, Joanie Selman

Bright Ideas Conference

Nursing programs educate adult students to the professional nursing role. Student nurses experience stressful learning environments related to advances in technology, patient demographics, national patient safety standards and high expectations in the clinical and classroom settings. One of the barriers to nursing student success is test anxiety, which potentially reduces student retention and graduation rates. Educators need to research and offer anxiety-relieving strategies to students to foster student success.


Integrating Institute Of Medicine (Iom) Core Competency Of Evidence-Based Management Practice With Senior Leadership Nursing Students, Rose Powell, Karen Migl Apr 2015

Integrating Institute Of Medicine (Iom) Core Competency Of Evidence-Based Management Practice With Senior Leadership Nursing Students, Rose Powell, Karen Migl

Bright Ideas Conference

The purpose of this project is to provide an environment for the senior leadership nursing student to analyze a current leadership/management research article and apply the findings to nursing management practice.


West Nile Virus, Sarene Smith, Preston Still Feb 2015

West Nile Virus, Sarene Smith, Preston Still

Infectious Diseases Project 2015

West Nile is a virus which means that West Nile is not a living organism and the only goal the virus has is to reproduce. The virus does this by taking over a host cell, attaching itself to the host cell and takes the cellular machinery needed to replicate itself. Once the virus is done and leaves, the host cell can also be used to infect other cells; therefore spreading the virus throughout the organism. (Campbell, Marfin, Lanciotti & Gubler, 2002).


Chagas Disease: “The Kiss Of Death”, Jessica Rogers, Stacy Castro Feb 2015

Chagas Disease: “The Kiss Of Death”, Jessica Rogers, Stacy Castro

Infectious Diseases Project 2015

Chagas disease is a vector transmitted disease also known as American trypanosomiasis. Chagas disease is classified as a protist or protozoa, which is a simplified version of ‘animal-like single celled organism that is like a multicellular organism’. This is because of the trypanosoma cruzi which is the protist itself (U.S. National Library of Medicine, 2012). This disease’s life cycle is complicated. The trypanosoma cruzi changes forms in its life cycle as it travels from hosts. The disease is first transmitted by the vector as it takes a blood meal. This is where the disease then takes over the cells near …


What Is Dysentery?, Rory Malek, Zach Hutchens Feb 2015

What Is Dysentery?, Rory Malek, Zach Hutchens

Infectious Diseases Project 2015

Dysentery is a disease that affects the digestive system and has many grotesque symptoms, such as diarrhea and vomiting. Dysentery is considered more of a set of symptoms instead of an actual organism, but it is almost always caused by a bacterium.


Yellow Fever, Harrison Gibbs, Emma Ward Feb 2015

Yellow Fever, Harrison Gibbs, Emma Ward

Infectious Diseases Project 2015

Yellow Fever is a disease that is most common in Africa and South America that causes severe discomfort and has a high mortality rate, of the estimated over 200,000 cases of Yellow Fever, 30,000 cases end in death. Since it is so dangerous, it is important to know how to prevent and treat it if someone ever wanted to travel to either of those places. The disease is relatively easy to avoid, all someone really need to do is avoid mosquitoes either by wearing protective clothing or by avoiding high density mosquito areas. If one were get Yellow Fever, they …


H1n1 Influenza Virus, Kail Consford, Drew Patel Feb 2015

H1n1 Influenza Virus, Kail Consford, Drew Patel

Infectious Diseases Project 2015

On April 17, 2009, two patients in the United States were found with Swine-Origin Influenza A (H1N1) virus. This virus was spread to Mexico, Canada, and many other countries. From April 15 through May 5, a total of 642 confirmed cases of H1N1 infection were identified in 41 states. The ages of the patients were from 3 months to 81 years, and 60% of the patients were 18 or younger. Most of these patients recently came from either Mexico or even from school outbreaks. The most common symptoms were fever, cough, and a sore throat. The H1N1 was determined to …


Lyme Disease, Marin Olson Beal Feb 2015

Lyme Disease, Marin Olson Beal

Infectious Diseases Project 2015

When asked to think of headlining diseases, many would choose bubonic plague, smallpox, Ebola, or leprosy. However, Lyme disease makes up for more confirmed diagnostic cases in the United States than all the aforementioned diseases combined. In 2014 alone, in the United States, 119 diagnostic cases were confirmed of bubonic plague, smallpox, Ebola, and leprosy altogether, while there were over 25,000 confirmed cases of Lyme disease (CDC, 2015). More information is needed to understand Lyme disease and how to treat it, before any more lives are lost.


Smallpox Infectious Disease, Miranda Allbee, Brandon Smith Feb 2015

Smallpox Infectious Disease, Miranda Allbee, Brandon Smith

Infectious Diseases Project 2015

Smallpox is a disease similar to chicken pox, but not exactly the same. Smallpox is caused by a virus called Variola and is a member of the genus orthopoxvirus. The virus is a large brick shaped DNA virus. Smallpox spreads by direct, face to face contact with an infected person or by contact with infected body fluids or contaminated objects such as clothing. Smallpox is rarely spread through airborne transmission and is not known to be transmitted by animals or insects. The incubation period lasts from 7 to 17 days, during which infected individuals often show no symptoms and are …


Crimean-Congo Hemorrhagic Fever, Reuben Ninan Feb 2015

Crimean-Congo Hemorrhagic Fever, Reuben Ninan

Infectious Diseases Project 2015

The Crimean-Congo Hemorrhagic Fever (CCHF) is a tick-borne infectious viral disease in the family Bunyaviridae. The disease was first characterized in the Crimea in 1944 and given the name Crimean hemorrhagic fever. CCHF was then later recognized in 1969 as the cause of illness in the Congo, thus resulting in the current name of the disease. CCHF causes severe viral hemorrhagic fever outbreaks (CDC, 2014).


The Bubonic Plague, Matthew Morin, Ashton Westbrook Feb 2015

The Bubonic Plague, Matthew Morin, Ashton Westbrook

Infectious Diseases Project 2015

The bubonic plague is a very serious infectious disease caused by the bacterium Yersinia pestis. The plague is a zoonotic disease, which means it is usually transmitted to humans by animals. It is commonly transmitted through the bites of infected fleas or coming in direct contact with infected animal tissue (Schoenstadt, 2006). The bacterium can be found in fleas or small rodents such as chipmunks, squirrels, rats, or prairie dogs. The symptoms, including fever, chills, headache, and hemorrhages under the skin causing discoloration, are very harsh and unpleasant. This disease is infectious and extremely severe, and it is deadly if …


Typhoid Fever, Christian Nicholas Feb 2015

Typhoid Fever, Christian Nicholas

Infectious Diseases Project 2015

Typhoid fever is a waterborne disease. There are a reported 16 million illnesses and 600,000 deaths annually (Crump, 2010). Most cases occur in developing countries; however, citizens of developed countries who visit developing ones are at risk of catching this disease (CDC, 2013). The disease is caused by Salmonella typhi, which infects the lymph nodes, necessary for immune response. Basic symptoms include a prolonged fever, interruptions in proper bowel function (constipation and diarrhea), severe cough, and in some cases, rose-colored spots on the patient. Salmonella typhi is a gram-negative bacteria that can only be carried by humans. There is also …


African Trypanosomiasis (Sleeping Sickness), Pedro Garcia, Austin Burton Feb 2015

African Trypanosomiasis (Sleeping Sickness), Pedro Garcia, Austin Burton

Infectious Diseases Project 2015

No abstract provided.


Dengue Fever, Ashley Hernandez, Chris Harkness Feb 2015

Dengue Fever, Ashley Hernandez, Chris Harkness

Infectious Diseases Project 2015

In recent years, the transmission of dengue fever has increased surprisingly fast and has become a major international public health concern. As of today this disease has mainly affected large countries and has become a leading cause of hospitalization and death among children in the certain areas. The amount of people that have got this infection has dramatically increase in recent decades. Over 40% of the world’s population are currently at risk of getting Dengue Fever. There is now an estimate of 50-100 million people that catch this disease every year (World Health Organization, 2002).


A Look Into Tuberculosis, Adrian Vega, Brennan Heath Feb 2015

A Look Into Tuberculosis, Adrian Vega, Brennan Heath

Infectious Diseases Project 2015

Tuberculosis is a Mycobacterium which is a genus classified in the phylum Actinobacteria. This genus is known to cause diseases in mammals. Tuberculosis' scientific name is Mycobacterium tuberculosis. Robert Koch discovered pathogenic bacterial species discovered in 1882 by. M. tuberculosis has a waxy coating on the cell's surface which makes it unable to be Gram stained.(Brennan, 2003). Gram staining is a method to differentiate bacterial species into two groups. This bacterium is Gram-negative because the waxy coating will not absorb the stain. When M. tuberculosis is in the lungs it is engulfed by macrophages trying to eradicate the disease, but …


Ebola Hemorrhagic Fever (Ebolavirus), Katie Mckee, Maria Hernandez Feb 2015

Ebola Hemorrhagic Fever (Ebolavirus), Katie Mckee, Maria Hernandez

Infectious Diseases Project 2015

Without treatment, the Ebola Virus (also known as hemorrhagic fever) has up to a 90% fatality rate. Understanding this disease could help save a person’s life, especially if that person has recently traveled to Africa.


Cholera Research Poster, James Sowards, Mac Duffield Feb 2015

Cholera Research Poster, James Sowards, Mac Duffield

Infectious Diseases Project 2015

Cholera kills 142,000 on average a year, each of these lives being equally important. In Haiti a huge outbreak of cholera occurred. So many people died it made the population unable to recover from such an epidemic. Cholera might not be as important to people that do not live near the area affected but it has changed the lives of many people around the world (WebMD LLC, 1994-2015).


Teaching Orientation And Mobility Skills To Students With Autism And Vision Impairment In Public Schools: A Data-Based Study, Devender, R. Banda, Phoebe A. Okungu Ph.D., Nora Griffin-Shirley, Melanie K. Meeks, Olaya Landa-Vialard Jan 2015

Teaching Orientation And Mobility Skills To Students With Autism And Vision Impairment In Public Schools: A Data-Based Study, Devender, R. Banda, Phoebe A. Okungu Ph.D., Nora Griffin-Shirley, Melanie K. Meeks, Olaya Landa-Vialard

Faculty Publications

Two students with autism, vision impairment, and intellectual disability participated in an orientation and mobility (O&M) intervention to travel in school settings using their folding canes. A multiple-baseline across participants design to determine the effectiveness of the intervention was used. The dependent variable was time taken to travel the specified route. The independent variable was O&M training. Results indicated that both participants took less time to travel during the intervention compared to the baseline. Students with vision impairment and autism can be trained using systematic O&M training. The O&M specialists working with children with autism and vision impairment should collect …


Brief Consultation To Families Of Treatment Refusers With Symptoms Of Obsessive Compulsive Disorder: Does It Impact Family Accommodation And Quality Of Life?, Melanie M. Vandyke, C. Alec Pollard, Jacob Harper, Kyle E. Conlon Jan 2015

Brief Consultation To Families Of Treatment Refusers With Symptoms Of Obsessive Compulsive Disorder: Does It Impact Family Accommodation And Quality Of Life?, Melanie M. Vandyke, C. Alec Pollard, Jacob Harper, Kyle E. Conlon

Faculty Publications

Family members are often directly and significantly impacted by the restrictive demands of OCD, a frequently disabling disorder. Family accommodation behaviors (i.e., doing things for or because of the OCD sufferer that a person would not normally do) are associated with dysfunction, including poorer treatment responses in OCD sufferers and greater distress in family members. Although evidence suggests family-based intervention can reduce symptoms in OCD sufferers who participate in treatment, there is a lack of research documenting the impact of interventions designed for the families of OCD treatment refusers (TR). Brief Family Consultation (BFC) was developed by our clinical team …


Experiences With Weight Loss Triggers In Women Prescribed To Lose Weight By Their Physician, Mark D. Faries, Elizabeth Espie, Erik Gnagy, Kyle P. Mcmorries Jan 2015

Experiences With Weight Loss Triggers In Women Prescribed To Lose Weight By Their Physician, Mark D. Faries, Elizabeth Espie, Erik Gnagy, Kyle P. Mcmorries

Faculty Publications

Background: With the global rise of individuals classified as overweight and obese, weight-related screenings have been promoted to combat their high prevalence and associated health problems. Hopefully, such screenings can act as a ‘trigger’ for health behavior change, however little is known about the experience of weight loss triggers.
Objectives: The aim of this study was to elaborate on the experiences and meanings of weight-control triggers in a sample of overweight women prescribed by their physician to lose weight.
Patients and Methods: We conducted exploratory qualitative interviews, grounded in phenomenological practices, to elaborate on the experience and meaning of weight …


The Relationship Of Female Physical Attractiveness To Body Fatness, Guanlin Wang, Kurosh Djafarian, Chima A. Egedigwe, Asmaa El Hamdouchi, Robert Ojiambo, Harris Ramuth, Sandra Johanna Wallner-Liebmann, Sonja Lackner, Adama Diouf, Justina Sauciuvenaite, Catherine Hambly, Lobke M. Vaanholt, Mark D. Faries, John R. Speakman Jan 2015

The Relationship Of Female Physical Attractiveness To Body Fatness, Guanlin Wang, Kurosh Djafarian, Chima A. Egedigwe, Asmaa El Hamdouchi, Robert Ojiambo, Harris Ramuth, Sandra Johanna Wallner-Liebmann, Sonja Lackner, Adama Diouf, Justina Sauciuvenaite, Catherine Hambly, Lobke M. Vaanholt, Mark D. Faries, John R. Speakman

Faculty Publications

Aspects of the female body may be attractive because they signal evolutionary fitness. Greater body fatness might reflect greater potential to survive famines, but individuals carrying larger fat stores may have poor health and lower fertility in non-famine conditions. A mathematical statistical model using epidemiological data linking fatness to fitness traits, predicted a peaked relationship between fatness and attractiveness (maximum at body mass index (BMI) = 22.8 to 24.8 depending on ethnicity and assumptions). Participants from three Caucasian populations (Austria, Lithuania and the UK), three Asian populations (China, Iran and Mauritius) and four African populations (Kenya, Morocco, Nigeria and Senegal) …