Medicine and Health Sciences Commons^™

Supporting Children With Disabilities At School: Implications For The Advocate Role In Professional Practice And Education, Stella Ng Phd

Stella Ng PhD

Purpose: School settings are a common practice context for rehabilitation professionals; health advocacy is a common and challenging practice role for professionals in this context. This study explored how pediatric practitioners advocate for children with disabilities at school. Specifically, we examined everyday advocacy in the context of school-based support for children with disabilities.

Method: Our theoretical framework and methodological approach were informed by institutional ethnography, which maps and makes visible hidden social coordinators of work processes with a view to improving processes and outcomes. We included families, educators, and health/rehabilitation practitioners from Ontario. Of the 37 consented informants, 27 were …

Dsm-5: The Delayed Demise Of Descriptive Diagnosis, Tomi Gomory

Tomi Gomory

In 1980, DSM-III adopted a descriptive approach to psychiatric diagnosis, creating checklists of unwanted behaviors to define and use as required criteria when posing each of several hundred diagnoses. The objective of this novel approach was to validate psychiatry as a scientifically legitimate branch of medicine, by enabling research into hopefully homogeneous groups of patients to pinpoint the implicit hypothesized physiological causes of the disorders the patients were presumably sharing. In each subsequent revision of the DSM including the DSM-5, however, no physiological criteria of any sort are included for any diagnosis, confirming the empirical failure of this attempt to …

Knowledge Of The Animal Welfare Act And Animal Welfare Regulations Influences Attitudes Toward Animal Research, Mitchell M. Metzger

Mitchell Metzger, PhD

No abstract provided.

Super Learner Analysis Of Electronic Adherence Data Improves Viral Prediction And May Provide Strategies For Selective Hiv Rna Monitoring., Maya Petersen, E Ledell, J Schwab, V Sarovar, R Gross, N Reynolds, J Haberer, K Goggin, C Golin, J Arnsten, M Rosen, R Remien, D Etoori, I Wilson, J Simoni, J Erlen, M Van Der Laan, H Liu, D Bangsberg

Maya Petersen

No abstract provided.

Increasing Obesity Awareness By Diagnosis Through Bmi In Primary Care, Ellie Yip

Ellie Yip

No abstract provided.

Addressing Prescription Opioid Abuse Concerns In Context: Synchronizing Policy Solutions To Multiple Public Health Problems, Kelly Dineen

Kelly Dineen

No abstract provided.

Estimating Controlled Direct Effects Of Restrictive Feeding Practices In The `Early Dieting In Girls' Study, Yeying Zhu, Debashis Ghosh, Donna L. Coffman, Jennifer S. Williams

Debashis Ghosh

In this article, we examine the causal effect of parental restrictive feeding practices on children’s weight status. An important mediator we are interested in is children’s self-regulation status. Traditional mediation analysis (Baron and Kenny, 1986) applies a structural equation modelling (SEM) approach and decomposes the intent-to-treat (ITT) effect into direct and indirect effects. More recent approaches interpret the mediation effects based on the potential outcomes framework. In practice, there often exist confounders that jointly influence the mediator and the outcome. Inverse probability weighting based on propensity scores are used to adjust for confounding and reduce the dimensionality of confounders simultaneously. …

Health Disclaimers And Website Credibility Markers: Guidance For Consumer Health Reference In The Affordable Care Act Era, Deborah H. Charbonneau

Deborah H. Charbonneau

This article reports on the current state of health disclaimers, online health resources, and credibility markers provided on public library websites (N = 105) for those seeking health information. In light of the Affordable Care Act (ACA), these findings have implications for consumer health reference services in public libraries. Approximately half of the public library websites in the study sample (n = 52, 49.5%) referred users to the ACA Health Insurance Marketplace website (HealthCare.gov). When referring to online consumer health resources, a small number of public library websites identified the authors of online health content (n = 16, 15.2%) or …

Surrogacy As The Sale Of Children: Applying Lessons Learned From Adoption To The Regulation Of The Surrogacy Industry's Global Marketing Of Children, David M. Smolin

David M. Smolin

This article will argue that most surrogacy arrangements as currently practiced do constitute the “sale of children” under international law, and hence should not be legally legitimated. Hence, maintaining the core legal norm against the sale of children requires rejecting currently constituted claims of a right to procreate through surrogacy. Given the underlying purpose of all human rights law in maintaining the inherent human dignity of all human beings, a claimed legal right built upon the sale of human beings must be rejected.

Personalizing Attribution Of Adverse Events In Phase I Oncology Studies, Alexia Iasonos, John O'Quigley

Alexia Iasonos

Background: In Phase I trials, attribution of adverse events (AE) is a complicated process. The current endpoint of dose limiting toxicity (DLT) assumes attribution is known. Such a simplified endpoint ignores individual-specific or drug-specific information. We propose an approach that allows for personalized scores that account for the uncertainty in AE attribution. Methods: The proposed design takes into account possible errors when attributing AE and allows investigators to explicitly express their degree of uncertainty in whether any AE is drug-related or disease-related. A score of 100% means that the AE is certainly drug-related, whereas a score of 0% means that …

The Importance Of Work Or Productive Activity In Life Care Planning And Case Management, Christine Reid, Susan Riddick-Grisham

Christine A. Reid

INTRODUCTION: The importance of work or productive activity for the well-being, community integration, and quality of life of people living with disabilities is addressed, with implications for life care planning and case management. BACKGROUND: The role of work or productive activity in our society, and consequences of deprivation if rehabilitation services do not address vocational effects of disabilities, is explored. A continuum of productivity options is introduced; types of vocational rehabilitation assessment processes and interventions are described. PURPOSE: The role of vocational rehabilitation services in life care planning and case management is discussed, focusing on quality of life for people …

Treatment Of Ebola Virus Disease., Paul E. Kilgore, Jd Grabenstein, Am Salim, M Rybak

Paul E. Kilgore

In March 2014, the largest Ebola outbreak in history exploded across West Africa. As of November 14, 2014, the World Health Organization has reported a total of 21,296 Ebola virus disease (EVD) cases, including 13,427 laboratory-confirmed EVD cases reported from the three most affected countries (Guinea, Liberia, and Sierra Leone). As the outbreak of EVD has spread, clinical disease severity and national EVD case-fatality rates have remained high (21.2-60.8%). Prior to 2013, several EVD outbreaks were controlled by using routine public health interventions; however, the widespread nature of the current EVD outbreak as well as cultural practices in the affected …

Clinical Evaluation Of A Loop-Mediated Isothermal Amplification (Lamp) Assay For Rapid Detection Of Neisseria Meningitidis In Cerebrospinal Fluid, Paul E. Kilgore

Paul E. Kilgore

BACKGROUND: Neisseria meningitidis (Nm) is a leading causative agent of bacterial meningitis in humans. Traditionally, meningococcal meningitis has been diagnosed by bacterial culture. However, isolation of bacteria from patients' cerebrospinal fluid (CSF) is time consuming and sometimes yields negative results. Recently, polymerase chain reaction (PCR)-based diagnostic methods of detecting Nm have been considered the gold standard because of their superior sensitivity and specificity compared with culture. In this study, we developed a loop-mediated isothermal amplification (LAMP) method and evaluated its ability to detect Nm in cerebrospinal fluid (CSF). METHODOLOGY/PRINCIPAL FINDINGS: We developed a meningococcal LAMP assay (Nm LAMP) that targets …

The Future Of Big Data: Innovative Methodological Approaches, Liz Mcconnell, Michelle Birkett, Mona Shattell Phd, Rn, Faan

Mona Shattell

No abstract provided.

Patient Experience Measurement Ignores Mental Health: Suggestions For Healthcare Organizations, Mona Shattell Phd, Rn, Faan, Andrew Gallan Phd

Mona Shattell

No abstract provided.

Engagement As An Element Of Safe Inpatient Psychiatric Environments, Michael Polacek, Diane Allen, Rabecca Damin-Moss, April Schwartz, David Sharpe, Mona Shattell Phd, Rn, Faan, Justin Souther, Kathleen Delaney

Mona Shattell

No abstract provided.

Towards Culturally Competent Professional Practice: Exploring The Concepts Of Independence And Interdependence, Wesam Darawsheh, Gill Chard

Gill Chard

Health and social care practitioners increasingly work with clients from diverse cultural backgrounds. While health and social care systems have emphasized the importance of culturally competent practice, professional practice has been influenced by values such as independence, a western notion that places value on the individual. It has been suggested that interdependence, a notion that places value on the family and/or community, can serve as an alternative to independence in culturally diverse practice. Using interviews

Randomized Phase Iii Trial Of Piroxicam In Combination With Mitoxantrone Or Carboplatin For First-Line Treatment Of Urogenital Tract Transitional Cell Carcinoma In Dogs., Sara D. Allstadt, C O. Rodriquez, B Boostrom, R B. Rebhun, K A. Skorupski

Sara Allstadt, DVM, Diplomate ACVIM (Oncology)

BACKGROUND: Reported response rates of transitional cell carcinoma (TCC) in dogs to piroxicam in combination with either mitoxantrone or carboplatin are similar; however, it is unknown whether either drug might provide superior duration of response. HYPOTHESIS/OBJECTIVES: To determine if the progression-free interval (PFI) of dogs with TCC treated with mitoxantrone and piroxicam was different than that of dogs receiving carboplatin and piroxicam. The hypothesis was that the efficacy of mitoxantrone is no different from carboplatin. ANIMALS: Fifty dogs with TCC without azotemia. METHODS: Prospective open-label phase III randomized study. Either mitoxantrone or carboplatin was administered every 3 weeks concurrently with …

Serum Cortisol Concentrations In Dogs With Pituitary-Dependent Hyperadrenocorticism And Atypical Hyperadrenocorticism, Linda Frank, George A. Henry, Jacqui C. Whittemore, B D. Enders, Dianne I. Mawby, Barton W. Rohrbach

Linda Frank MS, DVM, DACVD

BACKGROUND: Atypical hyperadrenocorticism (AHAC) is considered when dogs have clinical signs of hypercortisolemia with normal hyperadrenocorticism screening tests. HYPOTHESIS/OBJECTIVES: To compare cortisol concentrations and adrenal gland size among dogs with pituitary-dependent hyperadrenocorticism (PDH), atypical hyperadrenocorticism (AHAC), and healthy controls. ANIMALS: Ten healthy dogs, 7 dogs with PDH, and 8 dogs with AHAC. METHOD: Dogs were prospectively enrolled between November 2011 and January 2013. Dogs were diagnosed with PDH or AHAC based on clinical signs and positive screening test results (PDH) or abnormal extended adrenal hormone panel results (AHAC). Transverse adrenal gland measurements were obtained by abdominal ultrasound. Hourly mean cortisol …

Kisspeptin Receptor Agonist (Ftm080) Increased Plasma Concentrations Of Luteinizing Hormone In Anestrous Ewes, Brian K. Whitlock, Joseph A. Daniel, Lisa L. Amelse, Valeria M. Tanco, Kelly A. Chameroy, F Neal Shrick

Valeria M Tanco

Kisspeptin receptor (KISS1R) agonists with increased half-life and similar efficacy to kisspeptin in vitro may provide beneficial applications in breeding management of many species. However, many of these agonists have not been tested in vivo. These studies were designed to test and compare the effects of a KISS1R agonist (FTM080) and kisspeptin on luteinizing hormone (LH) in vivo. In experiment 1 (pilot study), sheep were treated with FTM080 (500 pmol/kg BW) or sterile water (VEH) intravenosuly. Blood was collected every 15 min before (1 hr) and after (1 hr) treatment. In experiment 2, sheep were treated with KP-10 (human Metastin …