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Purdue University

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2018

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Articles 1 - 22 of 22

Full-Text Articles in Medicine and Health Sciences

A Comparison Of Student Pharmacist Clinical Interventions During An Internal Medicine Advanced Pharmacy Practice Experience (Appe) In A High-Income Versus Low-Income Setting, Ellen Schellhase, Monica Miller, Shelby Wilkinson, Rakhi Karwa Dec 2018

A Comparison Of Student Pharmacist Clinical Interventions During An Internal Medicine Advanced Pharmacy Practice Experience (Appe) In A High-Income Versus Low-Income Setting, Ellen Schellhase, Monica Miller, Shelby Wilkinson, Rakhi Karwa

Engagement & Service-Learning Summit

Objectives: Compare and contrast the number and type of interventions made by student pharmacists who participated in an adult internal medicine APPE in the US to an internal medicine APPE in Kenya.

Methods: A US-based faculty-led, four-week internal medicine APPE with interprofessional team rounding that provides care for underserved patients in an urban setting and hosts 16 students annually was compared to a faculty-led, eight-week internal medicine APPE in Kenya that hosts on average 24 students annually. Starting May 2017 – January 2018 a standard clinical intervention collection form was used by all students on these two APPEs starting …


Assessment Of Intercultural Learning Within An Interdisciplinary Empathy Course Within An Honors College, Ellen Schellhase, Monica Miller Dec 2018

Assessment Of Intercultural Learning Within An Interdisciplinary Empathy Course Within An Honors College, Ellen Schellhase, Monica Miller

Engagement & Service-Learning Summit

Objective: The objective was to assess the intercultural learning of students enrolled in an interdisciplinary, active learning course with a focus on empathy and healthcare within an Honors College.

Methods:

This 2-credit course met twice weekly for active-learning session for 16 weeks. Topics covered included cultural dimensions, mindfulness, learning styles and four intercultural core competencies. Assignments included an intercultural development plan, on-line discussion board reflections for three required service-learning activities and completion of a Cultural Competence Badge. Students assessed their empathy using several different scales and completed the Intercultural Development Inventory (IDI) assessment at the beginning and end of the …


Construction And Nursing Students, Building A Playground For Bauer Family Services, Daphene Koch, Mary Erin Hoying, Deborah A. Spoerner, Rebecca C. Johnson, Abby Berg Dec 2018

Construction And Nursing Students, Building A Playground For Bauer Family Services, Daphene Koch, Mary Erin Hoying, Deborah A. Spoerner, Rebecca C. Johnson, Abby Berg

Engagement & Service-Learning Summit

Poster Session


Reimagining Print Materials In A Health Science Context: Creating And Marketing A Wellness Collection, Margaret Ansell, Ariel Pomputius Sep 2018

Reimagining Print Materials In A Health Science Context: Creating And Marketing A Wellness Collection, Margaret Ansell, Ariel Pomputius

Charleston Library Conference

In the healthcare field in which out-of-date information can harm patients, the currency and immediacy of digital collections is highly valued. As a result, many health science libraries have deselected much of their print collections (Haapanen, Kultamaa, Ovaska, & Salmi, 2015; Lingle & Robinson, 2009; Tobia & Hunnicutt, 2008; Xiaoli & Kopper, 2005). However, print materials continue to be valued by health science library users for a variety of purposes (Houghton, 2017; Watson, 2016). This paper describes how one academic health science center library found a role for print materials in the context of a wellness initiative, which (1) gave …


Where Are We? Providing Information For The Clinical Enterprise (17th Health Sciences Lively Lunch), Ramune K. Kubilius, Jean Gudenas, Laura Schimming, Jonathan Shank, Vida Vaughn, Neal Nixon Sep 2018

Where Are We? Providing Information For The Clinical Enterprise (17th Health Sciences Lively Lunch), Ramune K. Kubilius, Jean Gudenas, Laura Schimming, Jonathan Shank, Vida Vaughn, Neal Nixon

Charleston Library Conference

If the past is prologue to the future, where are we today? Though they are diverse, most academic health sciences libraries have historically described and continue to outline their missions as being directed to serving the education, research, and clinical information needs of their user populations. Over the years, Charleston Conference Health Sciences Lively Lunches have covered many themes, and in 2012, the focus was on the point of care information tools landscape. The 2017 17th Health Sciences Lively Lunch focused on issues and challenges of providing clinicians and clinical affiliates with access not only to point of care tools, …


Mass Spectrometry Image Creator (Msic): Ion Mobility / Mass Spectrometry Imaging Workflow In Python, Stephen Creger, Julia Laskin, Daniela Mesa Sanchez Aug 2018

Mass Spectrometry Image Creator (Msic): Ion Mobility / Mass Spectrometry Imaging Workflow In Python, Stephen Creger, Julia Laskin, Daniela Mesa Sanchez

The Summer Undergraduate Research Fellowship (SURF) Symposium

Mass spectrometry (MS) is a powerful characterization technique that enables identification of compounds in complex mixtures. Acquiring mass spectra in a spatially-resolved manner (i.e. over a grid), allows the data to be used to generate images that show the spatial distribution and relative intensities of every compound in a sample. These images can be used to monitor and identify biomarkers, explore the metabolism of compounds within tissues, and much more. However, the limitations of mass spectrometry can result in ambiguous compound identifications. Another characterization tool, ion mobility spectrometry (IM) can be integrated into existing MS routines to address this problem; …


Cost-Effective Paper-Based Diagnostic Using Split Proteins To Detect Yeast Infections, Zachary R. Berglund, Kevin V. Solomon, Mohit S. Verma, Moiz Rasheed, Zachary Hartley, Kevin Fitzgerald, Kok Zhi Lee, Janice Chan, Julianne Dejoie, Makayla Schacht, Alex Zavala Aug 2018

Cost-Effective Paper-Based Diagnostic Using Split Proteins To Detect Yeast Infections, Zachary R. Berglund, Kevin V. Solomon, Mohit S. Verma, Moiz Rasheed, Zachary Hartley, Kevin Fitzgerald, Kok Zhi Lee, Janice Chan, Julianne Dejoie, Makayla Schacht, Alex Zavala

The Summer Undergraduate Research Fellowship (SURF) Symposium

The common yeast infection, vulvovaginal candidiasis, affects three out of four women throughout their lifetime and can be spread to their child in the form of oral candidiasis (thrush). This disease is caused by the fungal pathogen Candida albicans, which is also a major cause of systemic candidiasis, a rarer but deadly disease with up to a 49% lethality rate. Current widely-used diagnostic methods include cell cultures, pH tests, and antibody detection, to assist effective treatment. Despite availability of various diagnostic methods, there is no inexpensive, rapid, and accurate way to detect C. albicans infection. This project aims to …


Polyrotaxane Variants And Their Effects On The Cholesterol Efflux In Patients Suffering From Niemann Pick Type C, Sydney Smith, Zach Struzik, David Thompson Aug 2018

Polyrotaxane Variants And Their Effects On The Cholesterol Efflux In Patients Suffering From Niemann Pick Type C, Sydney Smith, Zach Struzik, David Thompson

The Summer Undergraduate Research Fellowship (SURF) Symposium

Niemann Pick type C disease (NPC) is a rare lysosomal storage disorder characterized by a progressive accumulation of cholesterol in the late endosomal/lysosomes compartment leading to cellular dysfunction and organ failure. Symptoms include ataxia, dysarthria, cognitive dysfunction, and seizures. Although average life expectancy is below 20, there are no FDA approved treatment available making it a serious unmet medical need. Clinical trials with 2-hydroxypropyl-beta-cyclodextrin (HP-beta-CD) has shown promise in cholesterol normalization within NPC cells. However, HP-beta-CD treatment has been shown to cause ototoxicity in NPC patients at high dosages. Supramolecular complexes known as polyrotaxanes have been synthesized in hopes of …


Targeting Pro-Inflammatory Function Of Microglia Using Small Molecules To Combat Neurodegeneration, Gabrielle C. Williams, Priya Prakash, Gaurav Chopra Aug 2018

Targeting Pro-Inflammatory Function Of Microglia Using Small Molecules To Combat Neurodegeneration, Gabrielle C. Williams, Priya Prakash, Gaurav Chopra

The Summer Undergraduate Research Fellowship (SURF) Symposium

Microglia are the brain’s resident immune cells that are responsible for maintaining homeostasis in healthy conditions. During injury or infection, resting microglia get activated and produce pro-inflammatory cytokines such as IL-1b, IL-1a, IL-6, etc. along with reactive oxygen species like nitric oxide (NO) to combat neuroinflammatory diseases such as Alzheimer’s disease (AD). Inflammation is characterized by the activation of resident-immune cells in the brain called microglia that respond to the eat-me signals released by the toxic amyloid beta peptides as well as the dying neurons in the microenvironment. Recent studies have shown that activated microglia induce neuronal death by secreting …


Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio Aug 2018

Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio

The Summer Undergraduate Research Fellowship (SURF) Symposium

With metastasis accounting for approximately 90% of breast cancer deaths and an alarming number of over 300,000 new breast cancer cases to be diagnosed by the end of 2018, there is growing need to understand the process of breast cancer. Changes in the extracellular matrix (ECM) of the tumor microenvironment play an essential role in this deadly tumor progression. Specifically, the glycoprotein fibronectin (FN), has been identified to be up-regulated in patients with worse clinical outcomes. During tumor progression fibronectin undergoes conformational changes that aid in metastatic dissemination. In order to analyze the dynamic changes in FN expression and evaluate …


Targeting Neuropeptides To Bone Fractures For Accelerated Healing, Nicholas A. Young, Jeffery J. Nielsen, Philip S. Low Aug 2018

Targeting Neuropeptides To Bone Fractures For Accelerated Healing, Nicholas A. Young, Jeffery J. Nielsen, Philip S. Low

The Summer Undergraduate Research Fellowship (SURF) Symposium

In patients over the age of 65 especially, bone fractures represent a significant disease burden. Non-invasive drug therapies are not available for bone fractures which represents a problem for this population. Vasoactive intestinal peptide (VIP) and Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), two neuromodulator peptides in the glucagon superfamily, have demonstrated positive regulation of osteoblast proliferation and activity. Using acidic oligopeptides, we have developed ligands that target to and accumulate at fracture sites. These targeting ligands can be synthesized in sequence with bone anabolic peptides to minimize off target effects and increase potency at the fracture site to create safer and …


Understanding Qualitative 3d Shape From Texture And Shading, Benjamin Kunsberg, Steven W. Zucker May 2018

Understanding Qualitative 3d Shape From Texture And Shading, Benjamin Kunsberg, Steven W. Zucker

MODVIS Workshop

No abstract provided.


An Active Efficient Coding Model Of The Development Of Amblyopia, Samuel Eckmann, Lukas Klimmasch, Bertram Shi, Jochen Triesch May 2018

An Active Efficient Coding Model Of The Development Of Amblyopia, Samuel Eckmann, Lukas Klimmasch, Bertram Shi, Jochen Triesch

MODVIS Workshop

No abstract provided.


Use Of Excel Spreadsheet Calculators In Handling Data Generated From Uv- Spectrometer, Mercy Okezue, Kari Clase, Steve Byrn Mar 2018

Use Of Excel Spreadsheet Calculators In Handling Data Generated From Uv- Spectrometer, Mercy Okezue, Kari Clase, Steve Byrn

BIRS Symposium

To ease the complexities of handling data generated from different analytical procedures, validated excel spreadsheet containing relevant formulas are developed to ensure the process of data handling will consistently produce the expected results. This paper introduces the use of Excel spreadsheets in handling data generated from using a UV-Spectrometer in determination of analyte concentration in various dosage forms


Instituting Process Control Mechanisms In A Quality Control Analytical Chemistry Laboratory, Mercy Okezue, Kari Lynn Clase, Stephen Byrn Mar 2018

Instituting Process Control Mechanisms In A Quality Control Analytical Chemistry Laboratory, Mercy Okezue, Kari Lynn Clase, Stephen Byrn

BIRS Symposium

Statistical Process Control by means of using control charts was a means of monitoring performance of analytical equipment. Quality control checks on test items using these equipment generated data used for plotting X-bar charts. The charts generated had warning and control limits which helped monitor system performance


Approaches To Integrating Service Learning In The Public Health Administration Course, Sandra Liu, Ali Bianco Jan 2018

Approaches To Integrating Service Learning In The Public Health Administration Course, Sandra Liu, Ali Bianco

Engagement & Service-Learning Summit

No abstract provided.


Pharmacy Practice And Research: The Development Of A University Collaboration In Colombia, Ellen Schellhase Jan 2018

Pharmacy Practice And Research: The Development Of A University Collaboration In Colombia, Ellen Schellhase

Engagement & Service-Learning Summit

No abstract provided.


Water Supply In Developing Countries, Jason K. Hawes, Ernest R. Blatchley Iii, Audrey Caprio, Andrew T. Kanach Jan 2018

Water Supply In Developing Countries, Jason K. Hawes, Ernest R. Blatchley Iii, Audrey Caprio, Andrew T. Kanach

Engagement & Service-Learning Summit

No abstract provided.


Safety And Service-Learning: Engaging Pharmacy Students To Make Safer Communities, Patricia Darbishire, Chelsea Anderson Jan 2018

Safety And Service-Learning: Engaging Pharmacy Students To Make Safer Communities, Patricia Darbishire, Chelsea Anderson

Engagement & Service-Learning Summit

Poster Abstract

Objective:

To evaluate student perceptions of a service-learning experience for potential implementation in the curriculum.

Method:

A new 3-week intensive elective course was piloted in the Spring of 2017 at Purdue University College of Pharmacy. Seven third professional year students were included in the pilot and were divided into three groups. Each group of 2-3 students was assigned to one of 3 predetermined community partner sites. Students were taught how to perform a needs assessment and then designed a project targeted to improve safety at their site. Students completed a pre-post questionnaire that assessed their perceptions of the …


Implementation Of A Low-Cost Unna Boot Alternative As Adjunctive Treatment For Kaposi Sarcoma, Alexander Robert Mills, Edith Tonui, Sonak Pastakia, Rakhi Karwa, Phelix Were Jan 2018

Implementation Of A Low-Cost Unna Boot Alternative As Adjunctive Treatment For Kaposi Sarcoma, Alexander Robert Mills, Edith Tonui, Sonak Pastakia, Rakhi Karwa, Phelix Were

Engagement & Service-Learning Summit

There are 6 million people living with HIV; 70% reside in Sub-Saharan Africa (SSA). Furthermore, 1.1 million deaths occur due to opportunistic infections (OIs) that can be minimized with antiretroviral therapy. In Kenya, Kaposi Sarcoma (KS) is an especially debilitating OI that presents with dermatologic lesions; magnifying the stigma that patients with HIV face physically and psychosocially. Dermatology research is underway to determine the effectiveness of an unna boot (medicated, layered compression dressing) to speed the healing of these lesions with anecdotal success. Commercially available unna boot products are too expensive and not readily available in SSA. Clinicians from Purdue …


Expansion Of Pharmacy Students’ Involvement In Global Health And International Clinical Rotations, Alice C. Chang, Monica L. Miller, Ellen M. Schellhase Jan 2018

Expansion Of Pharmacy Students’ Involvement In Global Health And International Clinical Rotations, Alice C. Chang, Monica L. Miller, Ellen M. Schellhase

Engagement & Service-Learning Summit

No abstract provided.


Making Music To Enhance Mental Health In Eldoret, Kenya, Michael Peters, Ethan Wahle, Ellen Schellhase Jan 2018

Making Music To Enhance Mental Health In Eldoret, Kenya, Michael Peters, Ethan Wahle, Ellen Schellhase

Engagement & Service-Learning Summit

After attending this session, participants will be appreciate the power of music and witness the level of engagement that street youth in a resource-limited country have as they unite behind a common goal. Street youth in Eldoret, Kenya are at a high risk of experiencing psychological conditions like Post-traumatic Stress Disorder with contributing factors including homelessness, an unstable family structure, and exposure to alcoholism and drug abuse in parent figures. Music therapy has shown benefits in children to alleviate and manage some of the symptoms of emotional disturbances. The goal was to create a sustainable music program in Eldoret, Kenya …