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Full-Text Articles in Medicine and Health Sciences
Acquired Resilience: An Evolved System Of Tissue Protection In Mammals., Jonathan Stone, John Mitrofanis, Daniel M Johnstone, Benedetto Falsini, Silvia Bisti, Paul Adam, Arturo Bravo Nuevo, Mindy George-Weinstein, Rebecca Mason, Janis Eells
Acquired Resilience: An Evolved System Of Tissue Protection In Mammals., Jonathan Stone, John Mitrofanis, Daniel M Johnstone, Benedetto Falsini, Silvia Bisti, Paul Adam, Arturo Bravo Nuevo, Mindy George-Weinstein, Rebecca Mason, Janis Eells
PCOM Scholarly Works
This review brings together observations on the stress-induced regulation of resilience mechanisms in body tissues. It is argued that the stresses that induce tissue resilience in mammals arise from everyday sources: sunlight, food, lack of food, hypoxia and physical stresses. At low levels, these stresses induce an organised protective response in probably all tissues; and, at some higher level, cause tissue destruction. This pattern of response to stress is well known to toxicologists, who have termed it hormesis. The phenotypes of resilience are diverse and reports of stress-induced resilience are to be found in journals of neuroscience, sports medicine, cancer, …