Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Philadelphia College of Osteopathic Medicine

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 1 - 30 of 1250

Full-Text Articles in Medicine and Health Sciences

Is Radiofrequency Energy A Safe And Effective Treatment For Reducing Symptoms Of Gastroesophageal Reflux Disease In Patients 18 Years Or Older?, Kristen L. Schaffer Dec 2018

Is Radiofrequency Energy A Safe And Effective Treatment For Reducing Symptoms Of Gastroesophageal Reflux Disease In Patients 18 Years Or Older?, Kristen L. Schaffer

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence based medicine review is to determine whether or not “Is radiofrequency energy a safe and effective treatment for reducing symptoms of gastroesophageal reflux disease in patients 18 years or older?”

STUDY DESIGN: Review of two double-blind, randomized control trials and one double-blind, randomized cross-over study published between 2003 and 2012. All studies were published in the English language in peer reviewed journals.

DATA SOURCES: Two randomized control trials and one randomized cross-over study were found using PubMed.

OUTCOMES MEASURED: The outcomes measured include changes in GERD symptom scores for fourteen symptoms, improvement of ...


Cytoprotective Effects Of Natural Compounds Against Oxidative Stress, Jay Mehta, Srujana Rayalam, Xinyu Wang Oct 2018

Cytoprotective Effects Of Natural Compounds Against Oxidative Stress, Jay Mehta, Srujana Rayalam, Xinyu Wang

PCOM Scholarly Papers

Oxidative stress, an imbalance between reactive oxygen species and antioxidants, has been witnessed in pathophysiological states of many disorders. Compounds identified from natural sources have long been recognized to ameliorate oxidative stress due to their inherent antioxidant activities. Here, we summarize the cytoprotective effects and mechanisms of natural or naturally derived synthetic compounds against oxidative stress. These compounds include: caffeic acid phenethyl ester (CAPE) found in honey bee propolis, curcumin from turmeric roots, resveratrol abundant in grape, and 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl] imidazole (CDDO-Im), a synthetic triterpenoid based on naturally occurring oleanolic acid. Cytoprotective effects of these compounds ...


Germline Sdhb And Sdhd Mutations In Pheochromocytoma And Paraganglioma Patients, Yiqiang Huang, Lin-Ang Wang, Qiubo Xie, Jian Pang, Luofu Wang, Yuting Yi, Jun Zhang, Yao Zhang, Rongrong Chen, Weihua Lan, Dianzheng Zhang, Jun Jiang Oct 2018

Germline Sdhb And Sdhd Mutations In Pheochromocytoma And Paraganglioma Patients, Yiqiang Huang, Lin-Ang Wang, Qiubo Xie, Jian Pang, Luofu Wang, Yuting Yi, Jun Zhang, Yao Zhang, Rongrong Chen, Weihua Lan, Dianzheng Zhang, Jun Jiang

PCOM Scholarly Papers

Pheochromocytoma and paragangliomas (PCC/PGL) are neuroendocrine tumors that arise from chromaffin cells of the adrenal medulla and sympathetic/parasympathetic ganglia, respectively. Of clinical relevance regarding diagnosis is the highly variable presentation of symptoms in PCC/PGL patients. To date, the clear-cut correlations between the genotypes and phenotypes of PCC/PGL have not been entirely established. In this study, we reviewed the medical records of PCC/PGL patients with pertinent clinical, laboratory and genetic information. Next-generation sequencing (NGS) performed on patient samples revealed specific germline mutations in the SDHB (succinate dehydrogenase complex iron-sulfur subunit B) and SDHD(succinate dehydrogenase complex ...


Giant Bilateral Adrenal Myelolipomas In Two Chinese Families With Congenital Adrenal Hyperplasia, Qiuli Liu, Lin-Ang Wang, Jian Su, Dali Tong, Weihua Lan, Luofu Wang, Gaolei Liu, Jun Zhang, Victor Wei Zhang, Dianzheng Zhang, Rongrong Chen, Qingyi Zhu, Jun Jiang Sep 2018

Giant Bilateral Adrenal Myelolipomas In Two Chinese Families With Congenital Adrenal Hyperplasia, Qiuli Liu, Lin-Ang Wang, Jian Su, Dali Tong, Weihua Lan, Luofu Wang, Gaolei Liu, Jun Zhang, Victor Wei Zhang, Dianzheng Zhang, Rongrong Chen, Qingyi Zhu, Jun Jiang

PCOM Scholarly Papers

CONTEXT AND OBJECTIVES: Congenital adrenal hyperplasia (CAH) is one of the most prevalent, and potentially severe, genetic inborn errors of steroid synthesis directly affecting metabolism. Most patients are diagnosed and treated at an early age. There have been very limited reports of adults with CAH-associated adrenal myelolipomas. We aimed to analyze two families with CAH-associated giant adrenal myelolipomas caused by defects in CYP21A2 and CYP17A1 genes.

PARTICIPANTS AND METHODS: A total of 14 individuals from two unrelated families were identified with either CYP21A2 or CYP17A1 mutations. Of note, 5 patients were found with adrenal myelolipomas. Total DNA isolated from the ...


Management Of Enophthalmos From Silent Sinus Syndrome With A Customized Orbital Implant, Jason E. Cohn, Mofiyinfolu Sokoya, Mohammad Hararah, Sameep Kadakia, Yadranko Ducic Sep 2018

Management Of Enophthalmos From Silent Sinus Syndrome With A Customized Orbital Implant, Jason E. Cohn, Mofiyinfolu Sokoya, Mohammad Hararah, Sameep Kadakia, Yadranko Ducic

Otolaryngology (ENT) Resident Research

Background We describe the surgical treatment of silent sinus syndrome, a disease characterized by progressive enophthalmos and hypoglobus due to orbital floor collapse with opacification of the maxillary sinus, in the presence of chronic maxillary sinusitis.

Methods Case study of a 55-year-old male with persistent diplopia secondary to left-sided esotropia and enophthalmos from chronic maxillary sinusitis.

Results Two stage procedure to treat the sinonasal and orbital symptoms, which include endoscopic sinus surgery to treat the underlying the ostial obstruction along with decompression of maxillary sinus. Then, reconstruction of the orbital floor with a customized implant.

Conclusions Though the treatment of ...


Holmium Laser For Endoscopic Treatment Of Benign Tracheal Stenosis, D J. Verret, Arneya Jategaonkar, Samuel Helman, Sameep Kadakia, Arash Bahrami, Eli Gordin, Yadranko Ducic Jul 2018

Holmium Laser For Endoscopic Treatment Of Benign Tracheal Stenosis, D J. Verret, Arneya Jategaonkar, Samuel Helman, Sameep Kadakia, Arash Bahrami, Eli Gordin, Yadranko Ducic

Otolaryngology (ENT) Resident Research

Introduction Laryngotracheal stenosis is a difficult problem with varied etiology and various treatment options. The holmium laser represents another tool for the treatment of benign tracheal stenosis.

Objectives To determine the utility of holmium laser treatment for benign tracheal stenosis with regards to safety and efficacy.

Methods This was a retrospective case study examining patients with benign tracheal stenosis from 1998–2016 who underwent holmium laser treatment. Determining the safety of this procedure was the primary goal, and complications were monitored as a surrogate of safety.

Results A total of 123 patients who underwent holmium laser treatment for benign tracheal ...


Novel Genotype-Phenotype Correlations In Five Chinese Families With Von Hippel-Lindau Disease., Qiuli Liu, Gang Yuan, Dali Tong, Gaolei Liu, Yuting Yi, Jun Zhang, Yao Zhang, Lin-Ang Wang, Luofu Wang, Dianzheng Zhang, Rongrong Chen, Yanfang Guan, Xin Yi, Weihua Lan, Jun Jiang Jun 2018

Novel Genotype-Phenotype Correlations In Five Chinese Families With Von Hippel-Lindau Disease., Qiuli Liu, Gang Yuan, Dali Tong, Gaolei Liu, Yuting Yi, Jun Zhang, Yao Zhang, Lin-Ang Wang, Luofu Wang, Dianzheng Zhang, Rongrong Chen, Yanfang Guan, Xin Yi, Weihua Lan, Jun Jiang

PCOM Scholarly Papers

CONTEXT: Von Hippel-Lindau (VHL) disease manifests as a variety of benign and malignant neoplasms. Previous studies of VHL disease have documented several genotype-phenotype correlations; however, many such correlations are still unknown. Increased identification of new mutations and patients with previously described mutations will allow us to better understand how VHL mutations influence disease phenotypes.

PATIENTS AND DESIGN: A total of 45 individuals from five unrelated families were evaluated, of which 21 patients were either diagnosed with VHL disease or showed strong evidence related to this disease. We compared the patients' gene sequencing results with their medical records including computed tomography ...


Effect Of Putative Mitokatp Channel Blocker On Lipopolysaccharide-Induced Effects In Human Umbilical Vein Endothelial Cells, Indranie Ramsaroop Jun 2018

Effect Of Putative Mitokatp Channel Blocker On Lipopolysaccharide-Induced Effects In Human Umbilical Vein Endothelial Cells, Indranie Ramsaroop

PCOM Biomedical Studies Student Scholarship

Heart failure and high mortality rates are associated with severe sepsis. Recently, focus has been on mitochondrial ultrastructural changes and function due to sepsis and sepsis-related pathologies. Chopra et al. (2011) has provided data showing the involvement of the mitochondrial-mediated intrinsic apoptosis cascade in regulating adult rat ventricular myocyte (ARVM) dysfunction in sepsis. Experimental endotoxemia has shown mitochondrial membrane potential collapse, membrane permeability changes and release of cytochrome C to be indicators of mitochondrial dysfunction. Outer mitochondrial membrane (OMM) permeability is controlled by Bax translocation, resulting Voltage Dependent Anion Channels (VDACs) pores in the OMM and activation of mitoKATP channels ...


Art, Technology, Medicine: Creativity And Innovation In The Health Sciences, Skye Bickett, Erica Rosalle, Meghan Di Rito May 2018

Art, Technology, Medicine: Creativity And Innovation In The Health Sciences, Skye Bickett, Erica Rosalle, Meghan Di Rito

Research Day

Objectives: Our goal was to introduce our community to ways that creative or technological arts intersect with the healing arts. The event brought our community together for fun and stress relief, while teaching about different aspects of medical education, patient education, and therapy.

Methods: Drawing on the expertise of staff outside of the Library allowed us to enrich programming and make it interprofessional. The event had four components: Graphic Medicine, Art and Music Therapy, Gaming Technologies, and Health and Wellness. Each station included an example of the component, description of the modality, and a digital literature list.

Results: We asked ...


Assessment Of Appropriate Treatment Of Staphylococcus Aureus Bacteremia, Essie Samuel May 2018

Assessment Of Appropriate Treatment Of Staphylococcus Aureus Bacteremia, Essie Samuel

Research Day

Background: Staphylococcus aureus (S. aureus) when present within the bloodstream can result in increased rates of morbidity and 30-day all-cause mortality. Previous studies have assessed the significance of Methicillin-susceptible S. aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) bacteremia, where the treatment of choice is a β-lactam (or vancomycin if penicillin-allergic) or vancomycin, respectively. Rapid and appropriate antimicrobial selection is crucial for resolution of symptoms and prevention of relapse. For S.aureus bacteremia (SAB) treatment with systemic antibiotics, a short-course (14 days) can be utilized for uncomplicated cases and for patients with complicated SAB, long-course regimens are recommended at ≥ 4 weeks ...


Delayed Severe Drug Induced Cholestasis After Anabolic Steroids Exposure, Rashed A. Alfarra, Haris Hatic, Kelly M. Adkins, Shashi Poddar May 2018

Delayed Severe Drug Induced Cholestasis After Anabolic Steroids Exposure, Rashed A. Alfarra, Haris Hatic, Kelly M. Adkins, Shashi Poddar

Research Day

Anabolic steroids therapy is linked to a distinctive form of acute cholestasis that generally arises within 1 to 4 months of starting therapy but may be delayed to as long as 6 to 24 months in some reported cases. We are presenting an unusual case where acute cholestasis happened 5 weeks after discontinuing short course (7 days) of anabolic steroids.

A 20-year-old African American male without significant past medical history presented with jaundice, mild nausea and generalized pruritis. He admitted to self-initiation of oral Stanozolol 40 mg daily for 7-days about 5 weeks before his admission. No prior incidence and ...


Examining Addiction Treatment Facilities: An Observational Study From The Perspective Of Medical Students, Holly Hagle, Reshma Patel, Nidhi Patel, Abigail Buckholz May 2018

Examining Addiction Treatment Facilities: An Observational Study From The Perspective Of Medical Students, Holly Hagle, Reshma Patel, Nidhi Patel, Abigail Buckholz

Research Day

At the Institute for Research, Education, and Training in Addictions (IRETA), medical students are selected nationwide to learn about addiction and interact with patients undergoing treatment. It is well known that most medical schools do not provide significant training in addiction, and part of IRETA's goal is to remedy this need. In this study, medical students took observational field notes during site visits to various addiction treatment facilities. The data consisted of a comparison of treatment programs, as well as the results of motivational interviewing of patients. A thematic analysis was then conducted by the three students and the ...


Folate Deficiency In May-Thurner Syndrome, Haris Hatic, Suzanne Wang, Prasad S. Garimella May 2018

Folate Deficiency In May-Thurner Syndrome, Haris Hatic, Suzanne Wang, Prasad S. Garimella

Research Day

May–Thurner Syndrome (MTS) is a condition defined by an anatomical variant that results in the compression of the left common iliac vein by the right common iliac artery. This case report describes MTS in a Hispanic female with folate deficiency. 44-year-old Nicaraguan female who is a lifelong nonsmoker without any past medical history presented with left leg pain and swelling for seven days. The patient stated that her whole left leg was edematous without erythema. No recent travel, trauma, surgery or immobilization of the lower extremity. Initial vitals on presentation were unremarkable. Physical exam revealed a tender swollen of ...


Using Educational Board Games Adjunct To Traditional Lectures For Pharmacy Students In Learning Infectious Disease, Sirena Hu, Haley Ethredge, Drew Cates, Essie Samuel May 2018

Using Educational Board Games Adjunct To Traditional Lectures For Pharmacy Students In Learning Infectious Disease, Sirena Hu, Haley Ethredge, Drew Cates, Essie Samuel

Research Day

To determine if the utilization of modified games, such as ID-Candyland and ID-Taboo, are effective methods to reinforce student knowledge gained in traditional infectious diseases (ID) lectures. When confronted with various challenges of learning ID and the associated pharmacotherapy, pharmacy students often have difficulty applying knowledge learned within the traditional lecture setting to clinical practice and real-life situations involving patients. In addition to lectures and reading assignments, the utilization of educational games can extend learning opportunities, reinforce current understanding and promote a fun and competitive environment. Studies have shown that games are a powerful teaching strategy to develop creative learning ...


Implementing A Monitoring Program For Patients On Direct Oral Anticoagulants, Jiehyun Lee, Shally S. Singh, Michael L. Smith May 2018

Implementing A Monitoring Program For Patients On Direct Oral Anticoagulants, Jiehyun Lee, Shally S. Singh, Michael L. Smith

Research Day

Service or Program: The Backus Hospital Medication Management Clinic located in Norwich, CT provides a newly implemented Direct Oral Anticoagulant (DOAC) management service. This service is provided by a clinical pharmacist for patients with non-valvular atrial fibrillation or venous thromboembolism. The clinical pharmacist assists in the initiation, monitors for the efficacy and safety, and provides education on the benefits and risks of DOAC therapy. The clinical pharmacist communicates to the referring physicians on any significant concerns or recommendations with DOAC therapy. Lifestyle, renal function, and other medication use will be evaluated to ensure safety and stability. The referred patients will ...


Adenovirus Nephritis In Kidney Transplant Recipients: Clinical Features And Management, Osamuyi Idubor May 2018

Adenovirus Nephritis In Kidney Transplant Recipients: Clinical Features And Management, Osamuyi Idubor

Research Day

Background: Adenoviruses (AdV) are double-stranded DNA viruses that are well recognized as cause of significant morbidity and allograft dysfunction in transplant recipients. Adenovirus nephritis (AdN) can present with hemorrhagic cystitis or tubulointerstitial nephritis. Histological evaluation demonstrates interstitial inflammation, granulomas. Here we report 8 cases of AdN in kidney transplant recipients and their clinical course, management, and outcomes.

Methods: A retrospective search to identify cases of AdN in renal transplant recipients from 2009-2016 at the Emory Transplant Center.

Results: The diagnosis of AdN was confirmed by immunostaining on kidney transplant. All patients presented with complaints of constitutional symptoms; fever, dysuria, hematuria ...


A Correlative Blood Assay To Monitor Patients At Risk For Chemotherapy-Induced Peripheral Neuropathy, Angeleah Dadivas, Kinjal Parikh, John Kennedy, Amy Brady, Margaretha Wallon May 2018

A Correlative Blood Assay To Monitor Patients At Risk For Chemotherapy-Induced Peripheral Neuropathy, Angeleah Dadivas, Kinjal Parikh, John Kennedy, Amy Brady, Margaretha Wallon

Research Day

Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling side effect of platinum-based chemotherapies like cis-, oxali- and carboplatin. While not all patients experience this effect, those that do are at risk for lifelong neuropathy. Platinum-based therapies cause bursts of reactive oxygen species (ROS), which can trigger structural changes in peripheral nerves including neuronopathy, axonopathy and/or myelinopathy. Glutathione, an antioxidant, plays an important role in redox homeostasis. The recycling of glutathione can be determined by the ChemoTox assay and the aim of this study was to examine its ability to predict CIPN.

Methods: Blood drawn from consented and chemotherapy naïve ...


Penoscrotal Transposition: A Cadaveric Review, Paul Lecker, Dominic Parfianowicz, Jayaram Kumaraswamy, Sean Deangelo, Michael Mcguinness May 2018

Penoscrotal Transposition: A Cadaveric Review, Paul Lecker, Dominic Parfianowicz, Jayaram Kumaraswamy, Sean Deangelo, Michael Mcguinness

Research Day

Introduction: With only 20 documented cases, the congenital malformation known as complete extreme penoscrotal transposition with an intact scrotum, midline raphe, and absence of hypospadias is an extremely rare abnormality. Penoscrotal transposition occurs when the scrotum fuses above the penis for a complete abnormality or does not fuse at all for an incomplete abnormality. This failure of the scrotum to descend below the penis occurs during development, when the genital swellings fail to descend below the penis and fuse. The irregularity has been known to follow an X-linked recessive pattern in some cases. In others, it results from a defect ...


The Effect Of Caffeic Acid Phenethyl Ester (Cape) On H2o2-Induced Oxidative Stress In Cultured H9c2 Cells Compared To Common Antioxidants, Dylan Lefkowitz, Robinderpal Sandhu, Alisa Kim, Andrew Castellano, Peter Wieczorek, Robert J. Barsotti, Lindon H. Young, Qian Chen May 2018

The Effect Of Caffeic Acid Phenethyl Ester (Cape) On H2o2-Induced Oxidative Stress In Cultured H9c2 Cells Compared To Common Antioxidants, Dylan Lefkowitz, Robinderpal Sandhu, Alisa Kim, Andrew Castellano, Peter Wieczorek, Robert J. Barsotti, Lindon H. Young, Qian Chen

Research Day

Caffeic Acid Phenethyl Ester (CAPE) is a natural compound that has previously exhibited anti-proliferative, anti-inflammation and antioxidant activities. However, CAPE’s effects have not been fully elucidated in myoblasts under oxidative stress. We compared the effects of 24 hour pretreatment of CAPE to several known antioxidants (caffeic acid, vitamin C, and trolox) in H9c2 cells following oxidative injury by hydrogen peroxide (H2O2). H9c2 cells incubated with H2O2 treatment (100-700 μM, n=4) for 24 hours dose-dependently reduced cell viability (assessed by a cell counting assay). Compared to the reduction in viability from H2O2 500 μM treatment (22 ± 4%), H9c2 cell ...


The Role Of Autophagy During Myocardial Ischemia/Reperfusion Injury, Aloysius Ibe, Alisa Kim, Hannah Kim, Marquese Daniels, Lindon H. Young, Robert J. Barsotti, Qian Chen May 2018

The Role Of Autophagy During Myocardial Ischemia/Reperfusion Injury, Aloysius Ibe, Alisa Kim, Hannah Kim, Marquese Daniels, Lindon H. Young, Robert J. Barsotti, Qian Chen

Research Day

Autophagy is a housekeeping process to remove damaged cytoplasmic constituents. However, a debate persists on whether autophagy is beneficial or detrimental when an ischemic/reperfusion (I/R) insult occurs in the heart. This study tested the effects of autophagy enhancers (e.g. rapamycin and trehalose) and autophagy inhibitor (e.g. 3-methyladenine) on heart function and infarct size after global I (30 minutes) and R (45 minutes) when given prior to ischemia (pre-treatment) or at the beginning of reperfusion (post-treatment). We found that Rapamycin (25nM) pre-treatment and post-treatment significantly restored final left ventricular developed pressure (LVDP) to 75.4±9.1 ...


Modulation Of Nitric Oxide Release In Cultured Human Umbilical Vein Endothelial Cells By Myristoylated-Pkc Epsilon Activator/Inhibitor Peptides, George Ajene, Tameka Dean, Chantel Thompson, Wesley Hwang, Francis Jenney, Robert J. Barsotti, Qian Chen, Lindon H. Young May 2018

Modulation Of Nitric Oxide Release In Cultured Human Umbilical Vein Endothelial Cells By Myristoylated-Pkc Epsilon Activator/Inhibitor Peptides, George Ajene, Tameka Dean, Chantel Thompson, Wesley Hwang, Francis Jenney, Robert J. Barsotti, Qian Chen, Lindon H. Young

Research Day

Protein kinase C epsilon (PKCε) is known to increase endothelial nitric oxide synthase (eNOS) activity and subsequent nitric oxide (NO) release via phosphorylation at serine 1177 of eNOS in previous in vitro and in vivo animal studies under normoxic conditions. However, the role of PKCε regulating eNOS activity and NO release is not well known in human endothelial cells. Moreover, understanding the role of PKCε in regulating eNOS activity would be essential in the clinical setting of myocardial infarction. Re-establishing blood flow after thrombus removal results in endothelial dysfunction and is characterized by decreased NO bioavailability and excess reactive oxygen ...


Bioactive Peptides™ To Aid In Healing Of Chronic Skin Wounds And Tissue Repair, Elizabeth Brehman, Jonathan Mclaughlin, Stephanie Scianni, Charlotte H. Greene Phd, George Petito May 2018

Bioactive Peptides™ To Aid In Healing Of Chronic Skin Wounds And Tissue Repair, Elizabeth Brehman, Jonathan Mclaughlin, Stephanie Scianni, Charlotte H. Greene Phd, George Petito

Research Day

When wound healing of cutaneous tissue becomes problematic, it increases patient morbidity associated with increased infection, demand on medical resources, and asserts a profound detrimental effect on the individual’s quality of life. Currently, there are limited effective strategies for addressing chronic cutaneous wounds. The study reported here is based upon the understanding that individual skin wounds may preferentially require differing proteinaceous precursors during specific phases of skin wound repair and calls attention to the possibilities in the reexamination of traditional treatments such as plant and animal-derived substances among many others. This study aimed to determine if, and which, amino ...


Efficacy Of The Mnemonic Device “March Paws” As A Checklist For Pararescuemen During Tactical Field Care And Tactical Evacuation, Stephen Rush, John Kosequat, Alex Scott, Isabelle Gallo, Kent Swats, Ian Simonsen May 2018

Efficacy Of The Mnemonic Device “March Paws” As A Checklist For Pararescuemen During Tactical Field Care And Tactical Evacuation, Stephen Rush, John Kosequat, Alex Scott, Isabelle Gallo, Kent Swats, Ian Simonsen

Research Day

Background: The application of TCCC represents evidence-based medicine to improve survival in combat. Over the past several years, USAF Pararescuemen (PJs) have expanded the mnemonic device “MARCH” to “MARCH PAWS” for use during tactical field care and tactical evacuation. It stands for massive bleeding, airway, respiration, circulation, head and hypothermia, pain, antibiotics, wounds, and splinting. We undertook this performance improvement project to determine the efficacy of this device as a treatment checklist.

Methods: The mission reports of a sixteen PJs’ combat rescue deployment to OEF from January through June 2012 were reviewed. The triage category, mechanism of injury, injury, and ...


Clinical Assessment Of 4th Year Osteopathic Medical Students: Outdoor Medicine Rotation, Erik E. Langenau, Sarah Blazovic, Ashley Cochran, Sarah Corcoran, Elisa Guisto, Austin Sorchik, Cameron Williams May 2018

Clinical Assessment Of 4th Year Osteopathic Medical Students: Outdoor Medicine Rotation, Erik E. Langenau, Sarah Blazovic, Ashley Cochran, Sarah Corcoran, Elisa Guisto, Austin Sorchik, Cameron Williams

Research Day

Introduction: Securing clinical training sites remains a challenge for medical educators who often resort to paying preceptors or searching for new clinical training sites which haven’t traditionally taken students. We describe a unique partnership between the Boy Scouts of America and PCOM, providing a clinical training opportunity for OMS4 students at PCOM: Outdoor Clinical rotation the Summit Bechtel Family National Boy Scout Reserve in rural West Virginia at the National Scout jamboree, serving 35,000 scouts.

Methods and Curricular Design: By the end of the rotation, each PCOM student was able to (1) provide urgent care for common ...


A Case Of Persistent Median Artery Splitting The Median Nerve, Nicolette Alberti, Ilana Anmuth, Justin Canakis, David Bigley, Maryanne Lubas, Kevin Amuquandoh, Michael Mcguinness May 2018

A Case Of Persistent Median Artery Splitting The Median Nerve, Nicolette Alberti, Ilana Anmuth, Justin Canakis, David Bigley, Maryanne Lubas, Kevin Amuquandoh, Michael Mcguinness

Research Day

Introduction: Development of vascular abnormalities throughout the body are not uncommon. Little insight can be found regarding the clinical manifestations and development of these irregularities in the current data, indicating that further research needs to be done in order to gain full understanding of their implications. In the current case presentation, a persistent median artery (PMA) was identified in the left forearm of a cadaver. Normal vasculature of the forearm proceeds as follows; the brachial artery splits into the radial and ulnar arteries. The common interosseous artery branches off of the ulnar artery and then splits into an anterior and ...


Filming Trauma Simulations For Medical Education: A Comparison Of First-Person View Vs. Remotely Shot Video, Christopher Capicotto, Memu-Lye Kamara, John Krutsick, Arthur Sesso May 2018

Filming Trauma Simulations For Medical Education: A Comparison Of First-Person View Vs. Remotely Shot Video, Christopher Capicotto, Memu-Lye Kamara, John Krutsick, Arthur Sesso

Research Day

With advancements in video technology, first-person view places observers in the vantage point of the camera operator. Lightweight wearable products, such as GoPro cameras, are capable of capturing high-resolution footage. In a 3-phase project, first-person view (FPV) footage was compared to remotely-shot video (RSV) of identical trauma scenarios viewed by medical students and residents at PCOM.

Students responded to a trauma simulation by assessing the patient, obtaining a history and stabilizing the patient. This scenario was run once using RSV and again using FPV to capture the encounter. Both formats were screened for medical students in Phase I and Phase ...


Connecting Homeless Women To Primary Care Providers: The Effects Of A Student Advocacy Model, Hillary Brown, Rachael Blackmon, Christopher Gable, Jenny Glusman, Kerin M. Claeson May 2018

Connecting Homeless Women To Primary Care Providers: The Effects Of A Student Advocacy Model, Hillary Brown, Rachael Blackmon, Christopher Gable, Jenny Glusman, Kerin M. Claeson

Research Day

Introduction: The negative impact of homelessness on health, and the barriers that homeless individuals must overcome to access healthcare are well-documented. Primary care physicians often express difficulty in maintaining stable relationships with homeless patients, and access to free care clinics alone does not predict successful adherence to medical treatment. Motivation to seek care is also often cited as a barrier to adequate care.

Methods: The current study assesses the effects of a student-driven, decentralized primary care, and advocacy model on the chronic health conditions and task motivation of female patients. We do this through a pre/post model survey for ...


Comprehensive User Engagement Sites (Cues): Is This A Viable Option For The Opioid Epidemic In Philadelphia?, Siddardth Umapathy, Samuel Schadt, John Dubensky, Matthew Dimeglio, Sonul Gulati, Kevin Cooney, Olivia Nguyen, Priscilla Rodriguez, Marvin Lee, Peter Clark May 2018

Comprehensive User Engagement Sites (Cues): Is This A Viable Option For The Opioid Epidemic In Philadelphia?, Siddardth Umapathy, Samuel Schadt, John Dubensky, Matthew Dimeglio, Sonul Gulati, Kevin Cooney, Olivia Nguyen, Priscilla Rodriguez, Marvin Lee, Peter Clark

Research Day

INTRODUCTION: Opioid drug abuse has become an increasing concern throughout the United States, especially within the Philadelphia region. In 2017, the number of deaths by drug overdose were four times that of deaths by homicide. In addition, a total of 935 cases of secondary conditions due to needle sharing such as HIV and HCV occurred during the past year. The opioid epidemic has caused a public health emergency and any measures that could decrease the morbidity and mortality associated with opioid abuse are vital. A current proposal to combat this issue in Philadelphia is the implementation of a Comprehensive User ...


Evaluating The Impact Of Collaborative Care And Rehabiliation On Concussion Patients: Clinical Observations And Literary Review, Kevin Charan, Sarah Levin Allen May 2018

Evaluating The Impact Of Collaborative Care And Rehabiliation On Concussion Patients: Clinical Observations And Literary Review, Kevin Charan, Sarah Levin Allen

Research Day

Current research suggests that 1.6 - 3.8 million people each year suffer from concussions (Chin et al. 2016). The impact of concussions on the brain cannot be seen with traditional brain imaging, but screening tools can indicate whether the physical and cognitive symptoms presented are consistent with a concussion diagnosis. In addition to physical symptom reporting, concussion rehabilitation has shifted to focus on additional mental health factors. The aims of this capstone project were to gain a more in-depth understanding of the neurobiological and psychosocial factors influencing the recovery from a concussion, understand the rehabilitative process of a concussion ...


Evaluating The Neuropsychological Presentation Of Traumatic Brain Injuries, Eric Boxer, Sarah Levin Allen May 2018

Evaluating The Neuropsychological Presentation Of Traumatic Brain Injuries, Eric Boxer, Sarah Levin Allen

Research Day

This Neurobehavioral Capstone focused on traumatic brain injury (TBI), which is one of the leading causes of death and disability in the United States for children and young adults. TBI refers to a disruption of the brain’s normal functioning as a result of an acute external force. The most common causes for a TBI include falls, vehicular accidents, struck by or against an object, and assaults. The incidence for each cause of a TBI changes with respect to age. Severity of a TBI is determined using the Glasgow Coma Scale, which monitors the patient’s eye movements, verbal response ...