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Full-Text Articles in Medicine and Health Sciences

Changes In Hemodynamic Responses In Chronic Stroke Survivors Do Not Affect Fmri Signal Detection In A Block Experimental Design, Nutta-On Promjunyakul, Brian D. Schmit, Sheila Schindler-Ivens Sep 2013

Changes In Hemodynamic Responses In Chronic Stroke Survivors Do Not Affect Fmri Signal Detection In A Block Experimental Design, Nutta-On Promjunyakul, Brian D. Schmit, Sheila Schindler-Ivens

Physical Therapy Faculty Research and Publications

The use of canonical functions to model BOLD-fMRI data in people post-stroke may lead to inaccurate descriptions of task-related brain activity. The purpose of this study was to determine whether the spatiotemporal profile of hemodynamic responses (HDRs) obtained from stroke survivors during an event-related experiment could be used to develop individualized HDR functions that would enhance BOLD-fMRI signal detection in block experiments. Our long term goal was to use this information to develop individualized HDR functions for stroke survivors that could be used to analyze brain activity associated with locomotor-like movements. We also aimed to examine the reproducibility of HDRs …


Measuring Use Of Positive Thinking Skills: Psychometric Testing Of A New Scale, Abir K. Bekhet, Jaclene A. Zauszniewski Sep 2013

Measuring Use Of Positive Thinking Skills: Psychometric Testing Of A New Scale, Abir K. Bekhet, Jaclene A. Zauszniewski

College of Nursing Faculty Research and Publications

Positive thinking interventions improve adaptive functioning and quality of life in many populations. However, no direct measure of positive thinking skills taught during intervention exists. This psychometric study of a convenience sample of 109 autism spectrum disorder (ASD) caregivers examined a new eight-item Positive Thinking Skills Scale (PTSS), which measures the frequency of use of positive thinking skills. The PTSS was found to be internally consistent (α = .90). Construct validity was supported by significant correlations (p < .01) with positive cognitions (r = .53), resourcefulness (r = .63), depression (r = −.45), and general well-being (r = .40). The findings …


Methodology Issues In Implementation Science, Robin Newhouse, Kathleen Bobay, Patricia C. Dykes, Kathleen R. Stevens, Marita Titler Apr 2013

Methodology Issues In Implementation Science, Robin Newhouse, Kathleen Bobay, Patricia C. Dykes, Kathleen R. Stevens, Marita Titler

College of Nursing Faculty Research and Publications

Background: Putting evidence into practice at the point of care delivery requires an understanding of implementation strategies that work, in what context and how.

Objective: To identify methodological issues in implementation science using 4 studies as cases and make recommendations for further methods development.

Research Design: Four cases are presented and methodological issues identified. For each issue raised, evidence on the state of the science is described.

Results: Issues in implementation science identified include diverse conceptual frameworks, potential weaknesses in pragmatic study designs, and the paucity of standard concepts and measurement.

Conclusions: Recommendations to advance methods in implementation include developing …