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Articles 31 - 60 of 120
Full-Text Articles in Medicine and Health Sciences
Nursing Student Perceptions Regarding Simulation Experience Sequencing, Aimee A. Woda, Theresa Gruenke Schnable, Penny Alt-Gehrman, Jamie Hansen
Nursing Student Perceptions Regarding Simulation Experience Sequencing, Aimee A. Woda, Theresa Gruenke Schnable, Penny Alt-Gehrman, Jamie Hansen
College of Nursing Faculty Research and Publications
BACKGROUND:
The use of simulated learning experiences (SLEs) have increased within nursing curricula with positive learning outcomes for nursing students. The purpose of this study is to explore nursing students' perceptions of their clinical decision making (CDM) related to the block sequencing of different patient care experiences, SLEs versus hospital-based learning experiences (HLEs).
METHOD:
A qualitative descriptive design used open-ended survey questions to generate information about the block sequencing of SLEs and its impact on nursing students' perceived CDM.
RESULTS:
Three themes emerged from the data: Preexperience Anxiety, Real-Time Decision Making, and Increased Patient Care Experiences.
CONCLUSION:
Nursing students identified …
Pituitary Adenylate-Cyclase Activating Polypeptide Regulates Hunger- And Palatability-Induced Binge Eating, Matthew M. Hurley, Brian Maunze, Megan E. Block, Michael J. Reilly, Eugene Kim, Yao Chen, Yan Li, David A. Baker, Qing-Song Liu, Sujean Choi
Pituitary Adenylate-Cyclase Activating Polypeptide Regulates Hunger- And Palatability-Induced Binge Eating, Matthew M. Hurley, Brian Maunze, Megan E. Block, Michael J. Reilly, Eugene Kim, Yao Chen, Yan Li, David A. Baker, Qing-Song Liu, Sujean Choi
Biomedical Sciences Faculty Research and Publications
While pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the hypothalamic ventromedial nuclei (VMN) has been shown to regulate feeding, a challenge in unmasking a role for this peptide in obesity is that excess feeding can involve numerous mechanisms including homeostatic (hunger) and hedonic-related (palatability) drives. In these studies, we first isolated distinct feeding drives by developing a novel model of binge behavior in which homeostatic-driven feeding was temporally separated from feeding driven by food palatability. We found that stimulation of the VMN, achieved by local microinjections of AMPA, decreased standard chow consumption in food-restricted rats (e.g., homeostatic feeding); surprisingly, …
Mechanical Properties Of Natural Chitosan/Hydroxyapatite/Magnetite Nanocomposites For Tissue Engineering Applications, Fatemeh Heidari, Mehdi Razavi, Mohammad E. Bahrololoom, Reza Bazargan-Lari, Daryoosh Vashaee, Hari Kotturi, Lobat Tayebi
Mechanical Properties Of Natural Chitosan/Hydroxyapatite/Magnetite Nanocomposites For Tissue Engineering Applications, Fatemeh Heidari, Mehdi Razavi, Mohammad E. Bahrololoom, Reza Bazargan-Lari, Daryoosh Vashaee, Hari Kotturi, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Chitosan (CS), hydroxyapatite (HA), and magnetite (Fe3O4) have been broadly employed for bone treatment applications. Having a hybrid biomaterial composed of the aforementioned constituents not only accumulates the useful characteristics of each component, but also provides outstanding composite properties. In the present research, mechanical properties of pure CS, CS/HA, CS/HA/magnetite, and CS/magnetite were evaluated by the measurements of bending strength, elastic modulus, compressive strength and hardness values. Moreover, the morphology of the bending fracture surfaces were characterized using a scanning electron microscope (SEM) and an image analyzer. Studies were also conducted to examine the biological response …
Dental Applications Of Natural-Origin Polymers In Hard And Soft Tissue Engineering, Hossein E. Jazayeri, Mina D. Fahmy, Mehdi Razavi, Brett E. Stein, Aatif Nowman, Radi Masri, Lobat Tayebi
Dental Applications Of Natural-Origin Polymers In Hard And Soft Tissue Engineering, Hossein E. Jazayeri, Mina D. Fahmy, Mehdi Razavi, Brett E. Stein, Aatif Nowman, Radi Masri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Clinical advances in the treatment of dentoalveolar defects continue to evolve with the introduction of new innovations in regenerative medicine and tissue bioengineering. Recent developments in tissue engineering are aimed at safely and effectively regenerating a damaged or necrotic area by replenishing its cells and increasing surrounding gene expression. Various techniques have successfully given rise to porous scaffolds being used by clinicians to treat the defect and initiate the repair process. Tissue reconstruction using bioengineered scaffolds is advantageous over traditional autografting, since it prevents the instigation of pain and donor site morbidity while ultimately creating both the environment and machinery …
Quiet Time For Mechanically Ventilated Patients In The Medical Intensive Care Unit, Natalie S. Mcandrew, Jane Leske, Jill L. Guttormson, Sheryl Talcott Kelber, Kaylen Moore, Sylvia Dabrowski
Quiet Time For Mechanically Ventilated Patients In The Medical Intensive Care Unit, Natalie S. Mcandrew, Jane Leske, Jill L. Guttormson, Sheryl Talcott Kelber, Kaylen Moore, Sylvia Dabrowski
College of Nursing Faculty Research and Publications
Objective: Sleep disruption occurs frequently in critically ill patients. The primary aim of this study was to examine the effect of quiet time (QT) on patient sedation frequency, sedation and delirium scores; and to determine if consecutive QTs influenced physiologic measures (heart rate, mean arterial blood pressure and respiratory rate).
Method: A prospective study of a quiet time protocol was conducted with 72 adult patients on mechanical ventilation.
Setting: A Medical Intensive Care Unit (MICU) in the Midwest region of the United States.
Results: Sedation was given less frequently after QT (p = 0.045). Those who were agitated prior …
Accuracy And Precision Of Occlusal Contacts Of Stereolithographic Casts Mounted By Digital Interocclusal Registrations, Jason T. Krahenbuhl, Seok-Hwan Cho, Jon Patrick Irelan, Naveen K. Bansal
Accuracy And Precision Of Occlusal Contacts Of Stereolithographic Casts Mounted By Digital Interocclusal Registrations, Jason T. Krahenbuhl, Seok-Hwan Cho, Jon Patrick Irelan, Naveen K. Bansal
Mathematics, Statistics and Computer Science Faculty Research and Publications
Statement of problem
Little peer-reviewed information is available regarding the accuracy and precision of the occlusal contact reproduction of digitally mounted stereolithographic casts.
Purpose
The purpose of this in vitro study was to evaluate the accuracy and precision of occlusal contacts among stereolithographic casts mounted by digital occlusal registrations.
Material and methods
Four complete anatomic dentoforms were arbitrarily mounted on a semi-adjustable articulator in maximal intercuspal position and served as the 4 different simulated patients (SP). A total of 60 digital impressions and digital interocclusal registrations were made with a digital intraoral scanner to fabricate 15 sets of mounted stereolithographic …
Current Medical Research Winter/Spring 2016, Richard Fehring
Current Medical Research Winter/Spring 2016, Richard Fehring
College of Nursing Faculty Research and Publications
No abstract provided.
Collective Timekeeping Among Cells Of The Master Circadian Clock, Jennifer A. Evans
Collective Timekeeping Among Cells Of The Master Circadian Clock, Jennifer A. Evans
Biomedical Sciences Faculty Research and Publications
The suprachiasmatic nucleus (SCN) of the anterior hypothalamus is the master circadian clock that coordinates daily rhythms in behavior and physiology in mammals. Like other hypothalamic nuclei, the SCN displays an impressive array of distinct cell types characterized by differences in neurotransmitter and neuropeptide expression. Individual SCN neurons and glia are able to display self-sustained circadian rhythms in cellular function that are regulated at the molecular level by a 24h transcriptional–translational feedback loop. Remarkably, SCN cells are able to harmonize with one another to sustain coherent rhythms at the tissue level. Mechanisms of cellular communication in the SCN network are …
Lean Mass Predicts Conditioned Pain Modulation In Adolescents Across Weight Status, Stacy Stolzman, Marie K. Hoeger Bement
Lean Mass Predicts Conditioned Pain Modulation In Adolescents Across Weight Status, Stacy Stolzman, Marie K. Hoeger Bement
Physical Therapy Faculty Research and Publications
Background
There is a wide continuum of conditioned pain modulation (CPM) in adults with older adults experiencing an attenuated CPM response compared with younger adults. Less is known for adolescents and the role of anthropometrics.
Methods
Fifty-six adolescents (15.1 ± 1.8 years; 32 normal weight and 24 overweight/obese; 27 boys) completed in a CPM session that included anthropometric testing. Pressure pain thresholds were measured at the nailbed and deltoid muscle (test stimuli) with the foot submerged in a cool or ice water bath (conditioning stimulus). Weight status, body composition (Dual-energy X-ray absorptiometry scan), physical activity levels and clinical pain were …
Only Women Report Increase In Pain Threshold Following Fatiguing Contractions Of The Upper Extremity, Kathy J. Lemley, Jonathon Senefeld, Sandra K. Hunter, Marie K. Hoeger Bement
Only Women Report Increase In Pain Threshold Following Fatiguing Contractions Of The Upper Extremity, Kathy J. Lemley, Jonathon Senefeld, Sandra K. Hunter, Marie K. Hoeger Bement
Physical Therapy Faculty Research and Publications
Purpose
The perception of pain in response to a noxious stimulus can be markedly reduced following an acute bout of exercise [exercise-induced hypoalgesia (EIH)]. Sex differences in EIH frequently occur after exercise but may be confounded by the sex differences in muscle fatigue. The purpose was to determine if sex differences in pain relief occur after an exercise protocol when muscle fatigue is similar for both young and older men and women.
Methods
Pain perception of 33 men (15 young) and 31 women (19 young) was measured using a pressure pain stimulus on the left index finger before and after …
Wearing Complete Dental Prostheses - Effects On Perioral Morphology, Gregor F. Raschke, Philipp Eberl, Geoffrey A. Thompson, Arndt Guentsch, Andre Peisker, Stefan Schultze-Mosgau, Marta Gomez-Dammeier, Gabriel Djedovic, Ulrich M. Rieger, Florian Beuer
Wearing Complete Dental Prostheses - Effects On Perioral Morphology, Gregor F. Raschke, Philipp Eberl, Geoffrey A. Thompson, Arndt Guentsch, Andre Peisker, Stefan Schultze-Mosgau, Marta Gomez-Dammeier, Gabriel Djedovic, Ulrich M. Rieger, Florian Beuer
School of Dentistry Faculty Research and Publications
Background: To adequately perform rehabilitation of edentulous patients by a complete removable dental prosthesis (CRDP) is from basic interest to dentists to understand the morphologic changes caused by re-establishment of a physiologic jaw relationship. Anthropometric analyses of standardized frontal view and profile photographs may help elucidate such changes. Material and Methods: Photographs of 31 edentulous patients were compared in relaxed lip closure and after insertion of a CRDP in stable occlusion. 2232 anthropometric distances were raised. Eighteen anthropometric indices reflecting the perioral morphology and its integration in the vertical facial harmony were investigated. Results: The intercanthal – mouth width index …
Comparison Of The Transformation Temperatures Of Heat-Activated Nickel-Titanium Orthodontic Archwires By Two Different Techniques, Noor Aminah Obaisi, Maria Therese S. Galang-Boquieren, Carla A. Evans, Tzong Guang Peter Tsay, Grace Viana, David W. Berzins, Spiro Megremis
Comparison Of The Transformation Temperatures Of Heat-Activated Nickel-Titanium Orthodontic Archwires By Two Different Techniques, Noor Aminah Obaisi, Maria Therese S. Galang-Boquieren, Carla A. Evans, Tzong Guang Peter Tsay, Grace Viana, David W. Berzins, Spiro Megremis
School of Dentistry Faculty Research and Publications
Objectives
The purpose of this study was to investigate the suitability of the Bend and Free Recovery (BFR) method as a standard test method to determine the transformation temperatures of heat-activated Ni-Ti orthodontic archwires. This was done by determining the transformation temperatures of two brands of heat-activated Ni-Ti orthodontic archwires using the both the BFR method and the standard method of Differential Scanning Calorimetry (DSC). The values obtained from the two methods were compared with each other and to the manufacturer-listed values.
Methods
Forty heat-activated Ni-Ti archwires from both Rocky Mountain Orthodontics (RMO) and Opal Orthodontics (Opal) were tested using …
Longterm Quality Of Life After Oncologic Surgery And Microvascular Free Flap Reconstruction In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Korosh Roshanghias, Francy Eichmann, Stefan Schultze-Mosgau
Longterm Quality Of Life After Oncologic Surgery And Microvascular Free Flap Reconstruction In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Korosh Roshanghias, Francy Eichmann, Stefan Schultze-Mosgau
School of Dentistry Faculty Research and Publications
Background: Quality of life (QoL) has become increasingly important in cancer treatment. It refers to the patient’s perception of the effects of the disease and therapy, and their impact on daily functioning and general feeling of well being. Material and Methods: In this prospective study, a total of 100 patients treated at our institution, completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and the specific EORTC QLQ-H&N35 module. The questionnaires were distributed to the patients between 12 and 60 months postoperatively. Results: Global QoL score was 58.3 and mean score for functioning scale was 76.7. …
Parents’ Perspectives On Shared Decision Making For Children With Solid Organ Transplants, Stacee M. Lerret, Kristin Haglund, Norah L. Johnson
Parents’ Perspectives On Shared Decision Making For Children With Solid Organ Transplants, Stacee M. Lerret, Kristin Haglund, Norah L. Johnson
College of Nursing Faculty Research and Publications
Introduction
The Institute of Medicine prioritizes active family and clinician participation in treatment decisions, known as shared decision making (SDM). In this article we report the decision-making experiences for parents of children who had a solid organ transplant.
Method
We performed a prospective longitudinal mixed methods study at five major U.S. children's medical centers. Qualitative interview data were obtained at 3 weeks, 3 months, and 6 months after hospital discharge following the child's transplant.
Results
Forty-eight parents participated in the study. Three themes were identified: (a) Parents expect to participate in SDM; (b) parents seek information to support their participation …
Engaging Nursing Staff In Research: The Clinical Nurse Specialist Role In An Academic-Clinical Partnership, Lynn Gettrust, Mary E. Hagle, Lesley Boaz, Margaret J. Bull
Engaging Nursing Staff In Research: The Clinical Nurse Specialist Role In An Academic-Clinical Partnership, Lynn Gettrust, Mary E. Hagle, Lesley Boaz, Margaret J. Bull
College of Nursing Faculty Research and Publications
Purpose: The purpose of this article is to describe the processes of exploring and implementing an academic-clinical study, engaging nursing staff in research, and maintaining their enthusiasm within the context of an academic-clinical research partnership.
Description: The core competencies of the clinical nurse specialist (CNS) role address evidence-based practice, quality improvement, and research. Studies and exemplars of the CNS role in the literature illustrate expert practitioner and facilitator of evidence-based practice, but less attention is given to methods used by the CNS to engage staff in clinical research.
Outcome: The CNS was successful in obtaining staff engagement in the research …
Pilot Testing The Debriefing For Meaningful Learning Evaluation Scale, Cynthia Sherraden Bradley, Kristina Dreifuerst
Pilot Testing The Debriefing For Meaningful Learning Evaluation Scale, Cynthia Sherraden Bradley, Kristina Dreifuerst
College of Nursing Faculty Research and Publications
Background
Debriefing for Meaningful Learning (DML), an evidence-based debriefing method, promotes thinking like a nurse through reflective learning. Despite widespread adoption of DML, little is known about how well it is implemented. To assess the effectiveness of DML implementation, an evaluative rubric was developed and tested.
Sample
Three debriefers who had been trained to use DML at least 1 year previously, submitted five recorded debriefings each for evaluation.
Methods
Three raters who were experts in DML scored each of the 15 recorded debriefing session using DML Evaluation Scale (DMLES). Observable behaviors were scored with binary options. These raters also assessed …
Nurses' Own Birth Experiences Influence Labor Support Attitudes And Behaviors, Ann P. Aschenbrenner, Lisa Hanson, Teresa S. Johnson, Sheryl Talcott Kelber
Nurses' Own Birth Experiences Influence Labor Support Attitudes And Behaviors, Ann P. Aschenbrenner, Lisa Hanson, Teresa S. Johnson, Sheryl Talcott Kelber
College of Nursing Faculty Research and Publications
Objective
To describe the attitudes of intrapartum nurses about the importance of and intent to provide professional labor support (PLS); barriers to PLS, such as perceived subjective norms and perceived behavioral control; and relationships among attitudes, behaviors, and nurse and site characteristics.
Design
A cross-sectional, mixed-methods, descriptive design was guided by the Theory of Planned Behavior.
Setting
Three hospital sites in one region of a single Midwestern state.
Participants
Sixty intrapartum nurses participated.
Methods
The Labor Support Questionnaire and demographic questionnaire were administered online. The Labor Support Questionnaire is used to measure attitudes about the importance of and intended behaviors …
Evaluation Of An Oral Health Education Session For Early Head Start Home Visitors, Kevin Glatt, Christopher Okunseri, Diane Flanagan, Pippa Simpson, Yumei Cao, Earnestine Willis
Evaluation Of An Oral Health Education Session For Early Head Start Home Visitors, Kevin Glatt, Christopher Okunseri, Diane Flanagan, Pippa Simpson, Yumei Cao, Earnestine Willis
School of Dentistry Faculty Research and Publications
Objectives
Home visiting programs promote the education and health of Early Head Start (EHS) children and pregnant women. However, EHS's oral health component is unevenly implemented. We conducted an educational intervention to improve oral health knowledge and motivational interviewing techniques among Wisconsin EHS home visitors.
Methods
A questionnaire assessing oral health-related knowledge and confidence was administered to home visitors before and after an educational session. Changes between pre/post-responses were analyzed with McNemar's test and Wilcoxon Signed Rank test.
Results
After the intervention there were increases in both knowledge and confidence related to oral health communication. Knowledge increases were observed in …
Shared Care Contributions To Self-Care And Quality Of Life In Chronic Cardiac Patients, Margaret Sebern, Roger Brown, Patricia Flatley Brennan
Shared Care Contributions To Self-Care And Quality Of Life In Chronic Cardiac Patients, Margaret Sebern, Roger Brown, Patricia Flatley Brennan
College of Nursing Faculty Research and Publications
Shared care is an interpersonal interaction system composed of communication, decision making, and reciprocity; it is used by patients and family caregivers (care dyads) to exchange social support. This study’s purpose was to describe the contributions of shared care to outcomes for individuals with cardiac disease. A secondary data analysis was used to answer the following questions. What is the association between elements of shared care and patient outcomes? Do dyad perceptions of shared care differentially contribute to patient outcomes? Participants in this study were 93 individuals with a cardiac disease and 93 family caregivers. Composite index structured equation modeling …
Transition Of Experienced And New Graduate Nurses To A Pediatric Hospital, Carol Klingbeil, Rachel F. Schiffman, Carolyn Ziebert, Joan P. Totka, Catherine A. Schmitt, Lynn Doyle, Ashley Stelter, Alice V. Stonek, Weiming Ke, Norah L. Johnson
Transition Of Experienced And New Graduate Nurses To A Pediatric Hospital, Carol Klingbeil, Rachel F. Schiffman, Carolyn Ziebert, Joan P. Totka, Catherine A. Schmitt, Lynn Doyle, Ashley Stelter, Alice V. Stonek, Weiming Ke, Norah L. Johnson
College of Nursing Faculty Research and Publications
This study reports on the 3-, 6-, 12-, and 18-month outcomes of 118 newly hired registered nurses (RNs) who completed a 12-month transition-to-practice program at a pediatric hospital. Experienced RNs (n = 42) and new graduate RNs (n = 76) showed improved organization, prioritization, communication, and leadership skills over time. The experienced RNs reported better communication and leadership skills than the new graduate nurses. Results inform transition program development for both new and experienced nurses.
The American Association of Colleges of Nursing (2012) predicts that, without a multifaceted approach, a national nursing shortage will occur by 2020. Many nurses leave …
Submaximal Oxygen Uptake Kinetics, Functional Mobility, And Physical Activity In Older Adults With Heart Failure And Reduced Ejection Fraction, Scott L. Hummel, John Herald, Craig Alpert, Kimberlee A. Gretebeck, Wendy S. Champoux, Donald R. Dengel, Peter V. Vaitkevicius, Neil B. Alexander
Submaximal Oxygen Uptake Kinetics, Functional Mobility, And Physical Activity In Older Adults With Heart Failure And Reduced Ejection Fraction, Scott L. Hummel, John Herald, Craig Alpert, Kimberlee A. Gretebeck, Wendy S. Champoux, Donald R. Dengel, Peter V. Vaitkevicius, Neil B. Alexander
College of Nursing Faculty Research and Publications
Background: Submaximal oxygen uptake measures are more feasible and may better predict clinical cardiac outcomes than maximal tests in older adults with heart failure (HF). We examined relationships between maximal oxygen uptake, submaximal oxygen kinetics, functional mobility, and physical activity in older adults with HF and reduced ejection fraction.
Methods: Older adults with HF and reduced ejection fraction (n = 25, age 75 ± 7 years) were compared to 25 healthy age- and gender-matched controls. Assessments included a maximal treadmill test for peak oxygen uptake (VO2peak), oxygen uptake kinetics at onset of and on recovery from a submaximal treadmill test, …
Microfluidic Manipulation Of Core/Shell Nanoparticles For Oral Delivery Of Chemotherapeutics: A New Treatment Approach For Colorectal Cancer, Mohammad Mahdi Hasani-Sadrabadi, Shahrouz Taranejoo, Erfan Dashtimoghadam, Ghasem Bahlakeh, Fatemeh Sadat Majedi, Jules John Vandesarl, Mohsen Janmaleki, Fatemeh Sharifi, Arnaud Bertsch, Kerry Hourigan, Lobat Tayebi, Phillippe Renaud, Karl I. Jacob
Microfluidic Manipulation Of Core/Shell Nanoparticles For Oral Delivery Of Chemotherapeutics: A New Treatment Approach For Colorectal Cancer, Mohammad Mahdi Hasani-Sadrabadi, Shahrouz Taranejoo, Erfan Dashtimoghadam, Ghasem Bahlakeh, Fatemeh Sadat Majedi, Jules John Vandesarl, Mohsen Janmaleki, Fatemeh Sharifi, Arnaud Bertsch, Kerry Hourigan, Lobat Tayebi, Phillippe Renaud, Karl I. Jacob
School of Dentistry Faculty Research and Publications
A microfluidics approach to synthesize core–shell nanocarriers with high pH tunability is described. The sacrificial shell protects the core layer with the drugs and prevents their release in the severe pH conditions of the gastrointestinal tract, while allowing for drug release in the proximity of a tumor. The proposed nanoparticulate drug-delivery system is designed for the oral administration of cancer therapeutics.
Mentors And Role Models: Two Approaches For Inspiration, Gary L. Stafford
Mentors And Role Models: Two Approaches For Inspiration, Gary L. Stafford
School of Dentistry Faculty Research and Publications
No abstract provided.
Removable Partial Dentures Vs Overdentures In Children With Ectodermal Dysplasia: Two Case Reports, Georgios Maroulakos, Ioli I. Artopoulou, Matina V. Angelopoulou, Dimitris Emmanouil
Removable Partial Dentures Vs Overdentures In Children With Ectodermal Dysplasia: Two Case Reports, Georgios Maroulakos, Ioli I. Artopoulou, Matina V. Angelopoulou, Dimitris Emmanouil
School of Dentistry Faculty Research and Publications
Ectodermal dysplasia (ED) represents a disorder group characterised by abnormal development of the ectodermal derivatives. Removable partial dentures (RPD), complete dentures (CD) or overdentures (OD) are most often the treatment of choice for young affected patients. Prosthetic intervention is of utmost importance in the management of ED patients, as it resolves problems associated with functional, aesthetic, and psychological issues, and improves a patient’s quality of life. However, few studies present the principles and guidelines that can assist in the decision-making process of the most appropriate removable prosthesis. The purpose of this study was to suggest a simple treatment decision-making algorithm …
Effects Of Laryngeal Restriction On Pharyngeal Peristalsis And Biomechanics: Clinical Implications, Rita Shaker, Patrick Sanvanson, Gokulakrishnan Balasubramanian, Mark Kern, Ashley Wuerl, Allison Hyngstrom
Effects Of Laryngeal Restriction On Pharyngeal Peristalsis And Biomechanics: Clinical Implications, Rita Shaker, Patrick Sanvanson, Gokulakrishnan Balasubramanian, Mark Kern, Ashley Wuerl, Allison Hyngstrom
Physical Therapy Faculty Research and Publications
To date, rehabilitative exercises aimed at strengthening the pharyngeal muscles have not been developed due to the inability to successfully overload and fatigue these muscles during their contraction, a necessary requirement for strength training. The purpose of this study was to test the hypothesis that applying resistance against anterosuperior movement of the hyolaryngeal complex will overload the pharyngeal muscles and by repetitive swallowing will result in their fatigue manifested by a reduction in pharyngeal peristaltic amplitude. Studies were done in two groups. In group 1 studies 15 healthy subjects (age: 42 ± 14 yr, 11 females) were studied to determine …
Intersubunit Interactions At Putative Sites Of Ethanol Action In The M3 And M4 Domains Of The Nmda Receptor Glun1 And Glun2b Subunits, Robert W. Peoples, Hong Ren, Yulin Zhao
Intersubunit Interactions At Putative Sites Of Ethanol Action In The M3 And M4 Domains Of The Nmda Receptor Glun1 And Glun2b Subunits, Robert W. Peoples, Hong Ren, Yulin Zhao
Biomedical Sciences Faculty Research and Publications
Background and Purpose: The N-methyl-D-aspartate (NMDA) receptor is an important target of alcohol action in the brain. Recent studies in this laboratory have demonstrated that alcohol-sensitive positions in the intersubunit interfaces of the M3 and M4 domains of GluN1 and GluN2A subunits interact with respect to ethanol sensitivity and receptor kinetics, and that alcohol-sensitive positions in the M domains of GluN2A and GluN2B subunits differ. In this study we tested for interactions among alcohol-sensitive positions at the M domain intersubunit interfaces in GluN1/GluN2B NMDA receptors.
Experimental Approach: We used whole-cell patch-clamp recording in tsA201 cells expressing tryptophan substitution mutants at …
Three-Dimensional Bioprinting Materials With Potential Application In Preprosthetic Surgery, Mina D. Fahmy, Hossein E. Jazayeri, Mehdi Razavi, Radi Masri, Lobat Tayebi
Three-Dimensional Bioprinting Materials With Potential Application In Preprosthetic Surgery, Mina D. Fahmy, Hossein E. Jazayeri, Mehdi Razavi, Radi Masri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Current methods in handling maxillofacial defects are not robust and are highly dependent on the surgeon’s skills and the inherent potential in the patients’ bodies for regenerating lost tissues. Employing custom-designed 3D printed scaffolds that securely and effectively reconstruct the defects by using tissue engineering and regenerative medicine techniques can revolutionize preprosthetic surgeries. Various polymers, ceramics, natural and synthetic bioplastics, proteins, biomolecules, living cells, and growth factors as well as their hybrid structures can be used in 3D printing of scaffolds, which are still under development by scientists. These scaffolds not only are beneficial due to their patient-specific design, but …
Spirituality And Religiosity In Adolescents Living With Sickle Cell Disease, Dora L. Clayton-Jones, Kristin Haglund, Ruth Belknap, Jame Schaefer, Alexis A. Thompson
Spirituality And Religiosity In Adolescents Living With Sickle Cell Disease, Dora L. Clayton-Jones, Kristin Haglund, Ruth Belknap, Jame Schaefer, Alexis A. Thompson
College of Nursing Faculty Research and Publications
This study purports to address paucity in the literature regarding how adolescents with sickle cell disease (SCD) describe and experience spirituality and religiosity (S/R). This was a qualitative descriptive study. Two semi-structured interviews were conducted with nine adolescents (Mage = 16.2 years). Data were analyzed using a template analysis style and a concurrent analysis process of data reduction. Three major themes encompassed the participants’ descriptions of the relationships between S/R, health and illness in their lives including S/R as sources for coping, influence of S/R beliefs on health and illness, and sharing S/R with Health Care Providers (HCPs). …
Educating Family Caregivers For Older Adults About Delirium: A Systematic Review, Margaret J. Bull, Lesley Boaz, Martha G. Jermé
Educating Family Caregivers For Older Adults About Delirium: A Systematic Review, Margaret J. Bull, Lesley Boaz, Martha G. Jermé
College of Nursing Faculty Research and Publications
Background
Delirium in older adults is considered a medical emergency; it contributes to a cascade of functional decline and to increased mortality. Early recognition of delirium symptoms is critical to prevent these negative consequences. Family caregivers who are educated about delirium could partner with nurses and other healthcare professionals in early recognition of delirium symptoms. Before implementing such partnership models, it is important to examine the effectiveness of educating family caregivers about delirium.
Aims
To examine whether providing education on delirium to family caregivers improved their knowledge, emotional state, or response in reducing the incidence of delirium in older adults. …
Reliability And Validity Of Ratings Of Perceived Exertion In Persons With Multiple Sclerosis, Brice T. Cleland, Benjamin A. Ingraham, Molly C. Pitluck, Alexander V. Ng
Reliability And Validity Of Ratings Of Perceived Exertion In Persons With Multiple Sclerosis, Brice T. Cleland, Benjamin A. Ingraham, Molly C. Pitluck, Alexander V. Ng
Exercise Science Faculty Research and Publications
Objective: To test the reliability and validity of using the Borg rating of perceived exertion (RPE) scale (ratings 6e20) in persons with multiple sclerosis (PwMS).
Design: Nonrandomized repeated measures.
Setting: Research laboratory.
Participants: Volunteer sample (N=27) comprised of 16 PwMS (10 women) and 11 age-matched persons without multiple sclerosis (MS) (6 women). Clinical measures included symptomatic fatigue, depression, and MS functional capacity.
Interventions: A submaximal cycling test was performed to estimate maximal capacity. Participants then pedaled for 2 minutes at 50% and 60% of predicted maximal oxygen consumption per unit time (V̇O2), and physiological measures and RPE were …