Medicine and Health Sciences Commons^™

A New Project Echo Focused On Clinical Research In Development By The Nne-Ctr, Ivette Emery, Kerri Barton, Meredith Oestreicher, Neil Korsen, Irwin Brodsky

Costas T. Lambrew Research Retreat 2021

I diagram presented for the project by the NNE-CTR

Phq 9 Utilization In Maine Health, Steven Gerrish, Kerri Barton, Neil Korsen

Costas T. Lambrew Research Retreat 2021

The PHQ is a brief patient survey for diagnosing depression and monitoring response to treatment.

Notch Signaling Regulates Perivascular Adipose Tissue (Pvat) Function During Diet-Induced Obesity, C Yang, A Harrington, L Ryzhova, L Liaw

Costas T. Lambrew Research Retreat 2021

Objectives:

-To test the hypothesis that canonical Notch signaling influence vascular function by regulating PVAT-derived vascular relaxation factors.

-To determine how overexpression of Notch signaling or loss of the key Notch signaling component influence PVAT function.

Improving Diabetic Retinopathy Screening Rate In A Rural Primary Care Setting Using Point Of Care Ai Technology, Shane Kirkegaard

Costas T. Lambrew Research Retreat 2021

Point of Care AI Technology Poised to Improve Diabetic Retinopathy Screening Rate in Rural Primary Care Setting

Multiple Myeloma Cells Graphs And Figures Inhibit Adipogenesis, Increase Senescencerelated And Inflammatory Gene Transcript Expression, And Alter Metabolism In Preadipocytes, Michaela R. Reagan, Heather Fairfield, Samantha Costa, Carolyne Falank, Mariah Farrell, Connor S. Murphy, Anastasia D'Amico, Heather Driscoll

Costas T. Lambrew Research Retreat 2021

Myeloma cells alter metabolism & induce senescence in adipocyte-lineage cells, suggesting that senescence-associated proteins are involved in multiple myeloma.

Naloxone Co-Prescribing Across A Large Health System: A Quality Improvement Project, Marc D. Kimball, Sarah Hemphill, Kristen Silvia

Costas T. Lambrew Research Retreat 2021

Introduction:

• Naloxone availability and administration saves lives

• The CDC recommends naloxone co-prescribing for patients with OUD and other eligibility criteria

• Maine Medical Center’s baseline was found to be 6% in one clinic. This held true across the entire MaineHealth system.

Safe Injection To Prevent Infection: Specific Injection Practices Are Associated With Hepatitis C Exposure, Suggesting Opportunities For Targeted Harm Reduction Intervention For People Who Inject Drugs In Maine, N P. Sankar, K Murray, D Burris, K Thakarar

Costas T. Lambrew Research Retreat 2021

Background

• The U.S. opioid epidemic has contributed to an increase in infections related to IDU, such as HCV

• Transmission of HCV has been linked to unsafe injection practices

• This study aims to characterize risk factors associated with HCV exposure amongst people who inject drugs in Maine Methods

Process Evaluation Of A Smoking Cessation Group For Adults With Serious Mental Illness, David M. Weiss, Thomas Styron

Costas T. Lambrew Research Retreat 2021

Tobacco cessation strategies are needed to improve health outcomes among individuals with serious mental illness

The Maine Lung Cancer Coalition: A Statewide, Multi-Sector Partnership To Improve Evidence-Based Lung Cancer Prevention & Screening, Leo B Waterston, Liz Scharnetzki, Susan Leeds, Jaclyn A. Janis, Lee Lucas, Deborah Deatrick, Rebecca Boulos, Neil Korsen, Paul K.J. Han

Costas T. Lambrew Research Retreat 2021

MLCC has two primary goals:

1. Engage and educate about evidence based lung cancer prevention and screening practices

2. Develop, implement, and evaluate innovative programs to increase access to prevention, screening, and treatment services for all Mainers

The Nci/Nih Cancer Moonshot Biobank (Cmb) And The Maine Cancer Genetics/Genomics Education Core (Me-Cgec) Collaborate To Improve Cancer Care In Maine, Anne C. Breggia, Sue Miesfeldt, Neil Korsen, Jill Prescott, Lisa Lemire, Meghan Searight, Jamie Saunders, Scot Remick

Costas T. Lambrew Research Retreat 2021

Goal: To better understand drug resistance and sensitivity in patients with late stage (Stage III & IV) cancers that are receiving standard of care molecularly targeted therapies through next generation sequencing (NGS) of biopsy and blood samples collected longitudinally (diagnosis-- treatment--progression).

Thyroid Hormone-Clearing Deiodinase 3 Protects From Cranio- Encephalic And Cardiac Congenital Abnormalities, Arturo Hernandez, M Elena Martinez, Ilka Pinz, Marilena Preda, Thomas Gridley

Costas T. Lambrew Research Retreat 2021

Implications: Transient overexposure to TH during development may contribute to idiopathic congenital syndromes in humans (cleft palate, hydrocephalus, cardiac and Chiari malformations, others)

Would Surgeons Opt For Polypropylene Mesh If They Hypothetically Had Stress Urinary Incontinence Or Pelvic Organ Prolapse?, William J. Devan, Sanchita Bose, Dayron Rodriguez, Ricardo Munarriz, Linda Ng

Costas T. Lambrew Research Retreat 2021

Introduction

• Controversy surrounding vaginal mesh kits

• Many patients have negative connotations regarding mesh

• If patients were shown that their surgeons would opt for mesh –maybe this would help lessen the negativity?

Measuring Vastus Medialis Cross-Sectional Area With Panoramic Ultrasound Over Time, Kaitlin Minnehan, Elizabeth Scharnetzki, Kaitlyn Chin, Christina Holt, William Dexter

Costas T. Lambrew Research Retreat 2021

Panoramic ultrasound detected a statistically significant decrease in the VM CSA of participants after 70 days of bedrest without exercise.

Spiritual/Religious Orientation And Moral Distress In Pulmonary Care Nurses: An Exploration Of Ethical Norms, Moral Agency And Moral Resilience, Kristiina Hyrkas, Myrna Koonce

Costas T. Lambrew Research Retreat 2021

Introduction

• Nurses who provide care which they perceive as increasing suffering often experience moral distress (MD).

• Response to MD is a key factor in nurse wellbeing and retention, and is widely studied in nurses.

• Less research exists on foundations of moral belief and practice among nurses.

Improving Safety Using Hfmea And Insitu Simulation Prior To Initiating Contrast Mri Studies In An Ambulatory Setting, Micheline Chipman, Todd Dadaleares, Heather Beaulieu, Leah Mallory

Costas T. Lambrew Research Retreat 2021

The objective of this event was to test a new system for emergency response to MRI contrast reactions by ensuring staff familiarity with emergency equipment and a newly drafted emergency response protocols, and to mitigate any LST identified.

Dietary Patterns And Pfas Plasma Concentrations In Childhood: Project Viva, Usa, Shravanthi M. Seshasayee, Sheryl L. Rifas-Shiman, Jorge E. Chavarro, Jenny L. Carwile, Antonia M. Calafat, Sharon K. Sagiv, Emily Oken, Abby F. Fleisch

Costas T. Lambrew Research Retreat 2021

Children who adhered to a dietary pattern of primarily packaged foods and fish had higher plasma concentrations of select PFAS, reflective of food intake and/or correlated lifestyle factors.

Studying Emotions In Tele-Palliative Care, A Small Formative Study, Eric Anderson, Rebecca Hutchinson, Mollie Ruben, Noah Manning, Kathleen Walsh, Robert Gramling, Paul Han

Costas T. Lambrew Research Retreat 2021

Can emotional connection be formed in virtual consults?

A Simulation-Based Outreach Program Improves Delivery Room Team Confidence In Neonatal Resuscitation At Rural Community Hospitals, Allison Zanno, Misty Melendi, Micheline Chipman, Jeffrey Holmes, Alexa Craig, Samantha Piro, Anna Gilbert, Sarah Gabrielson, Leah Mallory, Anya Culter, Mary Ottolini

Costas T. Lambrew Research Retreat 2021

Objective- Our goal is to pilot the use of an onsite Neonatal Community Outreach Education Program to improve provider confidence with procedural skills and neonatal resuscitation in the delivery room.

The Mmc Biobank Is A Resource That Supports Biomedical Research, Anne C. Breggia, Sue Lapierre, Christopher Keister, Dawn Charnetzky, Hannah Brown, Joseph Nano, Sydney Robinson, Howard Feller, Susan Nester, Elizabeth Hamir, Heidi Ingersoll, Anthony Sellner, Trevor Jorgensen, Mike Jones

Costas T. Lambrew Research Retreat 2021

Mission: To provide normal and diseased annotated human biospecimens to the research community that supports discoveries leading to improved patient therapies and advances in personalized medicine.

Exploration Of Telemedicine For The Delivery Of Substance Use Disorder Treatment During The Covid-19 Pandemic, Rebecca Bell, Hannah Loeb, Michael Kohut, Eric Anderson, Kinna Thakarar, Rebecca Hutchinson

Costas T. Lambrew Research Retreat 2021

No abstract provided.

Telemedicine Consultation To Assess Neonatal Encephalopathy In Rural Community Hospitals, Rachel Coffey, Misty Melendi, Anya J. Cutler, Alexa K. Craig

Costas T. Lambrew Research Retreat 2021

We studied the feasibility of tele consults in community hospitals for neonatal encephalopathy evaluation.

Family Planning Outpatient Provider Survey; Evaluating Resident Confidence In Knowledge Of Family Planning Topics And Barriers To Providing Effective Care, Hannah Rosenfield, Kohar Der Simonian

Costas T. Lambrew Research Retreat 2021

The Question-

How do residents feel about their knowledge and skills in applying evidence- based care around contraception, miscarriage management and options counseling?

Mainehealth As A Partner In The National Covid Cohort Collaborative (N3c), Susan Santangelo, Ivette Emery, Kim Murray, John Dipalazzo, David Denton, Cliff Rosen

Costas T. Lambrew Research Retreat 2021

No abstract provided.

Resident Instruction In Social Emergency Medicine, Heidi Roche, Christine Knettel, Brandon Knettel, Justin Myers, Jessica Dunn, Timothy S. Fallon

Costas T. Lambrew Research Retreat 2021

Understanding social determinants of health (SDH) and their intersection with emergency medicine, also known as social emergency medicine (SEM), is an important area of EM training.

Prolonged Thunder Before The Storm – Diagnosis Of Aortobronchial Fistula After 28 Months Of Recurrent Hemoptysis, Hilamber Subba, Truc Ta, Edmund Sears

Costas T. Lambrew Research Retreat 2021

Aortobronchial fistula (ABF) should always be considered in patients with hemoptysis and previous thoracic surgery, however the diagnosis is known to be difficult both clinically and radiographically1. We present a case with the longest indolent course of hemoptysis reported to date .

Did Racial Representation Change At Our Outpatient Sports Medicine Clinic During The Covid-19 Pandemic?, William Douglas, William Dexter, Amy Haskins, Christina Holt

Costas T. Lambrew Research Retreat 2021

Introduction/Objective

• COVID-19 pandemic has disproportionately affected Black, Indigenous, and People of Color (BIPOC)

• Increased infection, hospitalization, and death rates1,2

• Black Americans unequal access to outpatient care vs. White Americans 3

• Inequity worsened during the COVID-19 Pandemic 4

• Maine population: 94.25% “White;” 1.42% “Black” 5

• July 2020 COVID cases: 66.8% “White;” 22% “Black” 6

• Did this disparity reflect in in our sports medicine clinic?

A Modified Sir Model Equivalent To A Generalized Logistic Model, With Standard Logistic Approximations, David E Clark, Jordan S Peck, Gavin Welch

Costas T. Lambrew Research Retreat 2021

No abstract provided.