Medicine and Health Sciences Commons^™

Nutrient Intake And Urine And Serum Calcium Response To A Low Calcium Diet And Repletion, Nancy Roberts

Loma Linda University Electronic Theses, Dissertations & Projects

A high percentage of American women do not consume the Recommended Dietary Allowance for calcium. Marginal intake of calcium (Ca) in the years when peak bone mass is being formed may have a detrimental impact on bone later in life. This study looked at the effect of low Ca intake and other dietary components on serum and urine values of Ca as well as the response to repletion.

Seventeen free-living females, age 21 to 30 years, were placed on a low Ca diet (/day) for 22 days after a baseline of intake >800 mg/day for at least 6 weeks. Calcibind …

Update - December 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The euthanasia debate in the Netherlands: Biolegal, bioethical and biotheological considerations

[ In Vito Fertilization and Divorce ]
-- What Can We Learn?
-- A Legal Perspective
-- Some Thoughts Regarding Frozen Embryos and Devorce

Concentration Of Leukotrienes B4 And C4 In Human Periradicular Lesions, Elisabetta Cotti

Loma Linda University Electronic Theses, Dissertations & Projects

The 5-lipoxygenase metabolites of arachidonic acid such as leukotrienes (LT) B₄ and C₄, are potent mediators of inflammation. The purpose of this investigation was to determine the concentrations of LTB₄ and LTC₄ in human periradicular lesions. Specimens from asymptomatic and symptomatic patients were obtained and immediately frozen in liquid nitrogen. Periradicular tissues from unerupted third molars as well as chronically inflamed gingival tissues were also obtained, frozen and were used as negative and positive controls respectively. The concentrations of LTB₄ and LTC₄ were determined by the reverse phase high pressure liquid chromatography. Representative …

Update - November 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Nancy Beth Cruzan and the Death of the Self

[ Can Ethics Be Taught? ]
-- Ethics Courses: Useless
-- Teaching Ethics is Vital
-- A Medical Ethics Course?
-- Is There No Place for Reason?

Update - October 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Richard Lamm highlights Ethics and Aging Project
-- A Personal View

[ The Nazi Doctors ]
-- Where Did They Go Wrong?
-- The Slippery Slide of Medical Ethics
-- From Health to Holocaust: Adventists and the Nazi Doctors

-- LLU's Ethics Center supports campaign against international tobacco trade

Assessment Of Maternal Substance Abuse And Neonatal Exposure, Carol Jean Dauenhauer Giese

Loma Linda University Electronic Theses, Dissertations & Projects

Infants born to adolescent and young adult mothers who abuse substances, are at high risk for chemical dependency and its sequelae. There is a need to identify such infants and their mothers so that intervention will be available to them. The purpose of this study was to develop a systematic approach to evaluate mothers and infants for potential drug use and improve the quality of the nurses decisions.

This research project involves two sub-projects. In Part A, a Substance Abuse Assessment Tool (SAAT) was developed. The hospital nurses used the SAAT March 1, 1990, through April 12, 1990. The incidence …

Commencement Program 1990 (Summer Conferring Of Degrees), Loma Linda University

Commencement Programs

CONTENTS

2 | Biography on Calvin B. Rock

3 | The Academic Procession

4 | Combined Conferring of Degrees

7 | Candidates for Degrees (Riverside Campus)

10 | Candidates for Degrees (Loma Linda Campus)

The Effects Of Moderate Exercise Training On Nutrient Intake In Mildly Obese Women, Leann Onasch

Loma Linda University Electronic Theses, Dissertations & Projects

The relationship between moderate exercise training (five 45 min sessions/week, brisk walking at 62+2% V0_2max for 15 weeks) and changes in nutrient intake was investigated in a group of 36 sedentary, mildly obese women, conducted using a two (exercise, EX and nonexercise, NEX groups) x three (baseline, six-, 15-week testing sessions) factorial design, with data analyzed using repeated measures ANOVA. The pattern of change over time between groups for kilocalorie intake tended to be different between groups [F(2,68)=2.50,p=0.089] with the EX group experiencing a significant decrease versus baseline by 15 weeks. Significant group x time interactions were found for …

Proto-Oncogene Regulation By Growth Factors In Bone Cells, Harold Lyndon Merriman

Loma Linda University Electronic Theses, Dissertations & Projects

Previous studies have shown that bone cells in culture produce a number of growth factors that are important in bone regulation. Chick and mouse primary calvarial cultures consist of a mixture of cell types that make it difficult to interpret the results from these model systems. In contrast, MC3T3-E1 cells are a clonal mouse osteoblast-like cell line. Since MC3T3-E1 cells consist of a single population of calvarial cells, they make an ideal system in which to study the autocrine effects of bone growth factors.

Based on this work, MC3T3-E1 cells are now known to produce IGF-I, TGF-beta and IGF-II in …

Development Of Catalytic Rnas As Potential Anti-Hiv-1 Agents, Pairoj Sae Chang

Loma Linda University Electronic Theses, Dissertations & Projects

RNA molecules with enzymatic activity (ribozymes) targeted to the genome of HIV-1 were developed and demonstrated to mediate site-specific cleavage of the HIV-1 RNA in vitro and to inhibit viral proliferation intracellularly. Two classes of ribozymes that incorporate a "hammerhead" catalytic center were utilized, eotide elements in the viral sequence to provide half of the The first class used nuclcatalytic center. A complementary strand harboring the remaining active site nucleotides was supplied in trans and directed the site-specific cleavage of the HIV-1 RNA target. A second type of ribozyme incorporated the entire catalytic center, minus the site of cleavage, within …

Standardization Of Oral Cloze As A Language Assessment Device For Bilingual Hispanic Children, Shannon Ventuleth

Loma Linda University Electronic Theses, Dissertations & Projects

This present study was initiated to determine the feasibility of oral cloze procedures as a language screening for bilingual Hispanic students. If such a procedure were normed, and proven to be both reliable and valid, the resultant assessment device would have potential screening tool as a for determining the presence of a language disorder in the bilingual Hispanic child aged 8 through 10 years.

A review of current tests available, and a review of the literature, revealed few language tests designed specifically for and normed on bilingual Hispanic children. Tests available for bilingual Hispanic children over 7 years of age …

Commencement Program 1990, Loma Linda University

Commencement Programs

CONTENTS

2 | 1990 Events of Commencement

3 | Academic Procession

4 | The Speakers

7 | The Honorees

10 | The Zapara Awards

Order of Program

• School of Medicine, 12
• School of Dentistry, 18
• Graduate School, 25
• School of Nursing, 30
• School of Public Health, 34
• School of Allied Health Professions, 41

A Modified Nance Unilateral Molar Distalizer, Tracy J. Reiner

Loma Linda University Electronic Theses, Dissertations & Projects

This clinical study evaluated a modified Nance appliance designed by the author to distalize molars unilaterally for Class II correction. This fixed appliance did not rely upon extraoral traction or intraoral elastics. Twelve unilateral Class II patients aged 13 to 17 were treated nonextraction with the appliance. Pretreatment and posttreatment photographs were taken of the palatal soft tissue and did not reveal any untoward changes as a result of the Nance acrylic button. All molars were corrected to an Angle's Class I relationship. Molar correction was evaluated visually and molar distalization was measured using an acrylic jig fitted to the …

Effect Of Glucose Administration On Hamster Liver S9-Mediated Mutagenesis, Metabolism And Dna-Binding Of Benzo[A]Pyrene And Aflatoxin B1, Daniel C. Rubano

Loma Linda University Electronic Theses, Dissertations & Projects

Hamster liver S9 prepared from control animals and animals given 30% glucose in drinking water 48 h before time of sacrifice was used in studies of benzo[a]pyrene (BaP) and aflatoxin (AFB₁)-induced mutagenesis, metabolism of BaP and AFB₁, and metabolite binding to calf thymus DNA. BaP-induced mutagenesis in Salmonella typhimurium TA100 was reduced 38.5% while AFB₁-induced mutagenesis was increased 36% by S9 from glucose-treated hamsters. The reduction of [³H]BaP metabolite binding to calf thymus DNA in incubations with S9 from glucose-treated hamsters correlated with a decrease in unknown BaP metabolite-deoxyribonucleoside adducts isolated by …

Evaluation Of Headgear Safety : A Comparative Study, William J. Pritchard

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine the relative safety of headgear safety straps. Samples from five different safety headgear straps simulated orthopedic and orthodontic use and data were collected from a series of pulls on an Instron machine. The straps were compared by the distance the face bow traveled before the safety mechanism released, the force built into the face bow at safety release and the force required to remove the inner bow out of the molar tube. The conclusions are as follows: (1) the distance a face bow can travel from the molar tube and still be …

The Long Term Stability Of The Dental Arches Following Rapid Palatal Expansion, Robert C. Stockdale

Loma Linda University Electronic Theses, Dissertations & Projects

The rapid palatal expander is an appliance which has been used to laterally expand the maxillary dental arch, with subsequent mandibular dental arch expansion.

The purpose of this study was to evaluate and quantify long term post treatment changes in the length and width of both dental arches following rapid palatal expansion.

Plaster models from eleven patients treated with rapid palatal expansion were obtained seven or more years after treatment. The dental arches were intact anterior to the first molars and no retreatment had taken place.

Maxillary and mandibular canine, premolar and molar arch width, arch length, arch circumference, and …

Characterization Of Hsd::Mudx128 Operon Fusion Mutant Of Escherichia Coli K-12, Marjorie Ann T. Reyno

Loma Linda University Electronic Theses, Dissertations & Projects

The study of the regulation of gene expression in complex genes can be facilitated by the use of operon fusions which place a well characterized lacZ gene under the control of a promoter of interest. An hsd::MudX128 operon fusion mutant of E. coli K-12 isolated by Prakash (1986) was observed to have a high β-galactosidase activity (1000 units), ten to twenty times higher than other hsd::MudX mutants. This β-galactosidase activity was suppressed to a very low level (25 units) by the introduction of an F’ plasmid, F'101, which carries the 98 min to 2 min region of the …

Maternal Immunomodulation Of Neonatal Alloantigen Response, Leh Chang

Loma Linda University Electronic Theses, Dissertations & Projects

Remarkable success has been achieved in the transplantation of allogeneic cardiac grafts into newborn infants at Loma Linda University Medical Center. The superior graft survival rate documented in these patients has not correlated with the degree of immunosuppression rendered, or the selection of genetically matched donors. However, the clinical success has correlated with the age of the recipient at the time of receiving a transplant. Patients receiving an allograft within the first few weeks of life are unique in that they seem to accept the alloantigens of their cardiac graft while responding aggressively to antigens in their environment. These observations …

Molar And Incisor Changes With Wilson "Rapid Molar Distalization", D. Dween Muse

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

Correlation Of Condylar Angulation To Occlusion, Facial Type, Age, And Sex, Perry A. Stevenson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine the correlation between the condylar angulation and the following variables: occlusion, facial type, depth of cut, overbite, overjet, interincisal angle, age, and sex. Pretreatment lateral cephalograms, submental vertex radiographs and study models were obtained for 114 patients (66 females, 48 males) with a mean age of 16 who were considered to have normal, asymptomatic temporomandibular joints. The results indicated that no significant correlation existed between the condylar angulation and the variables measured. Therefore, there is no method of predicting the condylar angulation by occlusion characteristics, facial type, age, or sex.

Active Treatment Time And Incisor Root Resorption Of Malocclusions Treated With Corticotomy Facilitated Orthodontics Vs. Non-Corticotomy Treatment, Douglas F. Tetz

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate the variables of treatment time and root resorption comparing subjects treated with corticotomy-facilitated orthodontics and controls treated by conventional methods. Twelve adult corticotomy subjects were utilized for the treatment time variable and seven of these subjects were utilized for the root resorption variable. These subjects were matched with non-corticotomized adult controls with regards to malocclusion, facial type, overbite, overjet and arch length deficiency. Average treatment time was found to be decreased by an average of 50% for those treated by corticotomy-facilitated orthodontics compared to non-corticotomy facilitated orthodontic care. Root resorption was significantly …

Update - May 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- James Walters wins NEH Grant
-- Fraud in Modern Medicine
-- Roy Branson serves as guest professor of medical ethics
-- Cambridge publishes Michael Pearson's study of Adventist ethics

[ RU486: Blessing or Curse? ]
-- Medical Aspects of RU486
-- The Curse of RU486: The Death Pill
-- RU486: A Very Mixed Blessing

-- Robert Wirth sparks aging project