Medicine and Health Sciences Commons^™

Imitation In Fragile X Syndrome: Implications For Autism, Marta Macedoni-Luksic, Laura Greiss Hess, Sally J. Rogers, David Gosar, Kerrie Lemons-Chitwood, Randi Hagerman

Occupational Therapy | Faculty Scholarship

To address the specific impairment of imitation in autism, the imitation abilities of 22 children with fragile X syndrome (FXS) with and without autism were compared. Based on previous research, we predicted that children with FXS and autism would have significantly more difficulty with non-meaningful imitation tasks. After controlling for full-scale IQ and age, the groups did not differ in their overall imitation accuracy scores, but analysis of error patterns revealed that children with FXS and autism made more groping errors and additional movements than the comparison group. These error patterns are consistent with the hypothesis that an action production …

Making The Connection: Creating Leaders In Research, Education, And Practice Through Doctoral Study In Occupational Science & Occupational Therapy, Carlin Lorena Daley, Courtney E. Daniels, Camille Marie Dieterle, Lisa D. Hickey, Karen Mccarthy, Elizabeth Pyatak, Tina C. Yang

Collected Faculty and Staff Scholarship

Current students and recent graduates of USC's OTD and PhD programs share innovative projects that address the Centennial Vision priority areas of practice. They share practical and creative strategies for bridging the gaps between research, education, and practice, and developing and implementing changes in a variety of practice settings.

Accumulation Of Artemisinin Trioxane Derivatives Within Neutral Lipids Of Plasmodium Falciparum Malaria Parasites Is Endoperoxide-Dependent, Carmony L. Hartwig, Andrew S. Rosenthal, John D'Angelo, Carol E. Griffin, Gary H. Posner, Roland A. Cooper

Collected Faculty and Staff Scholarship

The antimalarial trioxanes, exemplified by the naturally occurring sesquiterpene lactone artemisinin and its semi-synthetic derivatives, contain an endoperoxide pharmacophore that lends tremendous potency against Plasmodium parasites. Despite decades of research, their mechanism of action remains unresolved. A leading model of anti-plasmodial activity hypothesizes that iron-mediated cleavage of the endoperoxide bridge generates cytotoxic drug metabolites capable of damaging cellular macromolecules. To probe the malarial targets of the endoperoxide drugs, we studied the distribution of fluorescent dansyl trioxane derivatives in living, intraerythrocytic-stage Plasmodium falciparum parasites using microscopic imaging. The fluorescent trioxanes rapidly accumulated in parasitized erythrocytes, localizing within digestive vacuole-associated neutral lipid …

Motor Abilities Of Children Diagnosed With Fragile X Syndrome With And Without Autism, C. Zingerevich, L. G. Hess, K. Lemons Chitwood, S. W. Harris, D. Hessl, K. Cook, R. J. Hagerman

Collected Faculty and Staff Scholarship

Background—Previous studies suggested that children diagnosed with Fragile X Syndrome (FXS) often meet criteria for autism or PDD. This study describes the fine motor abilities of children diagnosed with FXS with and without autism spectrum disorder, and compares the motor scores of those groups controlling for cognitive level.

Method—Forty-eight children, ages 12-76 months (SD=16) diagnosed with FXS were assessed with the Mullen Scales of Early Learning, and the Autism Diagnostic Observation Schedule (ADOS). Their parents were interviewed with the Autism Diagnostic Interview-Revised (ADI-R). We used a one-way analysis of variance (ANOVA) to determine if the fine motor scale …

Promoting Mental Health Occupational Therapy In Higher Education: Lifestyle Redesign® For The College Student, Karen Mccarthy

Collected Faculty and Staff Scholarship

No abstract available

Mass Stranding Of Marine Birds Caused By A Surfactant-Producing Red Tide., David A. Jessup, Melissa A. Miller, John P. Ryan, Hannah M. Nevins, Heather A. Kerkering, Abdou Mekebri, David B. Crane, Tyler A. Johnson, Raphael M. Kudela

Natural Sciences and Mathematics | Faculty Scholarship

In November-December 2007 a widespread seabird mortality event occurred in Monterey Bay, California, USA, coincident with a massive red tide caused by the dinoflagellate Akashiwo sanguinea. Affected birds had a slimy yellow-green material on their feathers, which were saturated with water, and they were severely hypothermic. We determined that foam containing surfactant-like proteins, derived from organic matter of the red tide, coated their feathers and neutralized natural water repellency and insulation. No evidence of exposure to petroleum or other oils or biotoxins were found. This is the first documented case of its kind, but previous similar events may have gone …

Reflective Materials And The Use Of Glitter In Art Therapy, Amber Dee Mazza

Art Therapy | Master's Theses in Print

This paper hypothesizes that glitter is an important media in art therapy. This research asked the question, what is the significance and clinical application of glitter in art therapy? Glitter is a commonly used art material and research on the subject matter is absent. The method used was survey research with quantitative and qualitative questions. Seven hundred and fifty eight members of the American Art Therapy Association completed the survey. Glitter has significant meaning in reference to Cathy Moon’s theory of materiality, and can be used to bring light to client art work.