Medicine and Health Sciences Commons^™

The Effects Of Acute Beetroot Juice Ingestion On Upper And Lower Body Muscular Power During Weightlifting Exercise In Men, Grant Weiderman, Chandler Riley, Joanna Powell, Katie Price, Lauren Wideen, Andrew Fest, Justin Kim, Maya Hammer, Sean Karl, Isabella Lincoln, Noelle Seekamp-Hicks, Joshua Leow, Maddy Espinoza, Adam Pennell, Rachel Tan

Seaver College Research And Scholarly Achievement Symposium

Nitrate-rich beetroot juice (BR) supplementation improves movements with high-velocity and high-power muscle contractions which may be due to enhanced blood flow, oxygenation and contractile function in type II muscle fibers. The literature has focused predominantly on the effects of BR supplementation running and cycling performance, but its efficacy in resistance exercise, a modality that relies on type II muscle fibers, has limited data. Furthermore, it is unknown how supplementation strategies impact the physiological and ergogenic effects of BR during exercise. Therefore, the purpose of this study is to assess whether single or multi-day nitrate ingestion will improve performance and muscle …

Pomegranate Extract Supplementation On Neuromuscular Performance During Resistance Exercise, Katie Price, Joanna Powell, Matthew Joyner, Adam Pennell, Rachel Tan

Seaver College Research And Scholarly Achievement Symposium

Dietary nitrate supplementation has been shown to improve skeletal muscle function during high-velocity and high-power contractions due to its high nitrate levels; however, there is limited data examining its potential in exercise requiring these movements, such as resistance exercise. Nitrate supplementation has been studied extensively as beetroot juice, but its poor taste severely limits its application. Pomegranate extract (POM) may be an alternative nitrate source due to its superior taste, high nitrate content, and additional antioxidants but has yet to be explored. The purpose of the present study is two-fold: 1) to determine the nitrate concentration in POM; and 2) …

Effects Of 6-Week Basketball Training Using The Modified Circuit Weight Method, Jaroslaw Omorczyk, Tadeusz Ambroży, Ewa Puszczalowska-Lizis, Mateusz Nowak, Andrzej Markowski

Baltic Journal of Health and Physical Activity

The study aim was to evaluate the effect of a 6-week modified workout routine using the modified circuit weight method on selected anthropometric measures, components of physical fitness and physiological indices in competitive basketball players. The study involved 30 basketball players (mean age: 23.4 ±1.8 years). Modified circuit weight method sessions were repeated 3 times a week. Each training session was subdivided into 3 circuits: strength conditioning, exercises to enhance functional fitness and a circuit of sport-specific exercises. Statistically significant differences in values of circumferences and skinfolds were found between pre-test and post-test values, with no statistically significant changes in …

Impact Of Menstrual Phases On Stress Markers: A Pilot Study, Bailey C. Weishaar, Hunter S. Waldman, Kyle T. Patek, Matthew J. Mcallister

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Previous research has shown that different phases of the menstrual cycle may impact biometrics such as markers of stress and inflammation [e.g., cortisol (CORT), interleukin-6] as well as body composition. However, there is scarce literature regarding markers of stress and oxidative stress such as salivary a-amylase (sAA), immunoglobin-A (SIgA) and uric acid (UA), in relation to the four different menstrual phases. The purpose of this study was to examine the impact of menstrual phases on sAA, CORT, UA and SIgA. METHODS: 21 pre-menopausal women with regular menstrual cycles (n=9) oral contraceptive users (OC) and ( …

Calpain-Mediated Protein Targets In Cardiac Mitochondria Following Ischemia–Reperfusion, Ling Li, Jeremy Thompson, Ying Hu, Edward J. Lesnefsky, Belinda Willard, Qun Chen

Internal Medicine Publications

Calpain 1 and 2 (CPN1/2) are calcium-dependent cysteine proteases that exist in cytosol and mitochondria. Pharmacologic inhibition of CPN1/2 decreases cardiac injury during ischemia (ISC)–reperfusion (REP) by improving mitochondrial function. However, the protein targets of CPN1/2 activation during ISC–REP are unclear. CPN1/2 include a large subunit and a small regulatory subunit 1 (CPNS1). Genetic deletion of CPNS1 eliminates the activities of both CPN1 and CPN2. Conditional cardiomyocyte specific CPNS1 deletion mice were used in the present study to clarify the role of CPN1/2 activation in mitochondrial damage during ISC–REP with an emphasis on identifying the potential protein targets of CPN1/2. …

Pulmonary Capillary Recruitment And Distention In Mammalian Lungs: Species Similarities, David Langleben, Benjamin D. Fox, Stylianos E. Orfanos, Michele Giovinazzo, John D. Catravas

Bioelectrics Publications

Pulmonary arterial pressure rises minimally during exercise. The pulmonary microcirculation accommodates increasing blood flow via recruitment of pulmonary capillaries and, at higher flows, by distention of already perfused capillaries. The flow transition range between recruitment and distention has not been studied or compared across mammalian species, including humans. We hypothesised that the range would be similar. Functional pulmonary capillary surface area (FCSA) can be estimated using validated metabolic techniques. We reviewed data from previous studies in three mammalian species (perfused rabbit lungs and dog lung lobes, and exercising humans) and generated blood flow-FCSA curves over a range of flows. We …

Pre-Season Body Composition Has Minimal Influence On In-Season Match Availability, And Match Performance In Female Australian Football League (Aflw) Players, Callum J. Mccaskie, Marc Sim, Robert U. Newton, Jarryd Heasman, Brent Rogalski, Nicolas H. Hart

Research outputs 2022 to 2026

This study examined the relationship between pre-season body composition, in-season match performance, and match availability in female players competing in the Australian Football League Women's (AFLW) competition. With the outlawing of body composition assessments as part of pre-draft player evaluations in the AFLW, this study seeks to examine whether this is justified. Twenty-two (n = 22) players had body composition assessed with dual-energy x-ray absorptiometry at the beginning of the 2021 AFLW pre-season (whole-body and regional fat mass and lean soft-tissue mass [LSTM]). In-season match availability and match performance data (Coaches Score [CS], Champion Data Player Rank, average disposals, disposal …

Cardiorespiratory Fitness Level Alters Blood Pressure Responses Induced By Histamine H1- And H2-Receptor Blockade During Dynamic Exercise, Albert A. Lira Jr., Dustin J. Lirazan, Ronaldo U. Meneses, Sung J. Yun, Jong-Kyung Kim

International Journal of Exercise Science: Conference Proceedings

Epidemiological studies have reported that greater cardiorespiratory fitness (CRF) is associated with lower blood pressure (BP). Histamine receptor-mediated peripheral vasodilation contributes to postexercise hypotension and lowing exercising BP responses. Previously, our laboratory found that overactive BP responses to exercise were induced by the inability of histamine receptors in individuals with prehypertension. However, it is still unknown that CRF can impact BP responses elicited by the inability of the receptors. Purpose: This study was to assess whether aerobic fitness is effective in lowering excessive BP responses induced by the blockade of histamine receptors. Methods: In twelve male and female subjects (6 …

Acute Effect Of Dietary Supplementation With Grape Seed Extract Attenuates Blood Pressure Increase During Cold Pressor Test In Prehypertensive Men, Sarah Greenawalt, Albert A. Lira Jr., Kylie J. Morrison, Ronaldo U. Meneses, Christen J. Lutz, Savannah C. Ulhir, Jong-Kyung Kim

International Journal of Exercise Science: Conference Proceedings

It is well documented that prehypertension or hypertension is associated with sympathetic overdrive and loss of parasympathetically mediated cardiac variability. Previous studies demonstrated that increased NO bioavailability reduced central sympathetic output. Despite the fact that grape seed extract (GSE) treatment increases the production of NO and improves endothelial function in prehypertensive males, no studies have assessed the effects of GSE on autonomic balance and autonomic function. PURPOSE: the aim of the study was to investigate the acute effect of dietary GSE supplementation on heart rate variability (HRV) and cold pressor test (CPT). METHODS: Six males were recruited in this study. …

Reinvigorating A Technical Countering Weapons Of Mass Destruction Distance Learning Graduate Certificate Program, James C. Petrosky, Gaiven Varshney, Jeremy Slagley, Sara Shaghaghi

Faculty Publications

Current Countering Weapons of Mass Destruction (CWMD) demands can be divided broadly into policy and science. The science of chemical, biological, and radiological/nuclear weapons informs the limits of development, production, employment, operation, detection, risk characterization, human and material protection, and medical intervention. In short, the science of weapons of mass destruction (WMD) should precede and inform the development of policy. It is to this end that the Air Force Institute of Technology (AFIT) CWMD program was re-established, providing a technical educational option for practitioners to understand the science behind a very technically challenging subject.

Lcd 207: Anatomy And Physiology For Speech And Language, Yael Neumann

Open Educational Resources

This course is an introduction to the anatomy and physiology of the respiratory, phonatory, articulatory, resonatory, and nervous systems as they relate to voice, swallowing, speech production and language systems.

Comparative Analysis Of Longevity And Stress Resiliency Benefits Of Supplementation With High-Antioxidative Capacity Juices In Organisms That Are Representative Of Humans, Meghan Long

Honors Scholar Theses

Neurodegenerative disease presents itself in a complex array of illnesses that is increasingly affecting the geriatric population. There has not been research on a common cause since there are a culmination of reasons that are probable ranging from genetic to environmental factors. Antioxidants have been known to prevent and protect against the damage that is otherwise caused by reactive oxygen species (ROS). Thus, high-capacity antioxidant juices supplemented into the diet of animal models such as Caenorhabditis elegans, Drosophila melanogaster, rats, and humans will allow for the study of the possible benefits.

Although a conclusion and common causation on the usage …

Anatomy And Physiology Preparatory Course Textbook (2nd Edition), Carlos Liachovitzky

Open Educational Resources

The goal of this preparatory textbook is to give students a chance to become familiar with some terms and some basic concepts they will find later on in the Anatomy and Physiology course, especially during the first few weeks of the course.

Organization and functioning of the human organism are generally presented starting from the simplest building blocks, and then moving into levels of increasing complexity. This textbook follows the same presentation. It begins introducing the concept of homeostasis, then covers the chemical level, and later on a basic introduction to cellular level, organ level, and organ system level. This …

Tight Trip Vs. Loose Grip On Russian Kettlebell Swing Work Capacity, Austin Deshner, Abigail Mccarty, Jerrell C. Campbell, Andrew Fields, Will W. Peveler

Masters Theses

The purpose of this study was to examine the effects of a tight grip(TG) and a loose grip(LG) on work capacity while performing Russian kettlebell swings(KBS). It was hypothesized that LG would result in an ability to perform more work. Thirty fit adults (16 male; 14 female) were tested. Two (TG and LG) separate counterbalanced trials for each subject were collected, counting the number of repetitions completed until volitional exhaustion. RPE for forearms and overall exhaustion were collected post-trial. SPSS was used to run a paired samples t-test. There was a significant difference between the two grips (p = 0.013)(TG …

Vitamin D3 Induces Mesenchymal-To-Endothelial Transition And Promotes A Proangiogenic Niche Through Igf-1 Signaling, Lei Chen, Anweshan Samanta, Lin Zhao, Nathaniel R. Dudley, Tanner Buehler, Robert J. Vincent, Jeryl Hauptman, Magdy Girgis, Buddhadeb Dawn

School of Medicine Faculty Publications

Biological Sciences; Physiology; Molecular Biology; Cell Biology

Characteristics Of Physiology And Physiology-Related Pre-Health Degree Programs In The Physiology Majors Interest Group, Yvonne Ogrodzinski, Erica A. Wehrwein, Kevin Kelly, James M. Poteracki, Valerie Vanryn, Anne R. Crecelius

Health and Sport Science Faculty Publications

The Physiology Majors Interest Group (P-MIG), a grassroots organization of educators, has collected data on the history and characteristics of Physiology and highly related undergraduate programs (ex: Human Biology, Pre-Medicine, Biomedical Sciences, etc.) that serve a common population of prehealth students. Data was obtained as part of an online survey sent out to P-MIG conference attendees at the 2017-2019 annual meetings (n=30). Participating institutions indicate that 25.9% have degrees called Physiology aligned with 28% being housed in a department of physiology, 75.9% are a Bachelor of Science program, 34.9% are affiliated with a College of Arts and Sciences, and 80% …

Track And Field Athlete's Barriers Evolving With The Postponement Of The Olympics, Jessica Rabius, Marycatherine Harmon

International Journal of Exercise Science: Conference Proceedings

Due to the global Coronavirus pandemic the International Olympic Committee, IOC, rescheduled the Summer Olympics to a date beyond 2020, but not later than summer 2021, to safeguard the health of everyone involved in the Games. As the Olympics have been postponed, this could consequently affect track and field athletes. The only other time in the history of the Olympics that there has been a postponing or canceling has been in the case of a war. PURPOSE: The purpose of this study was to study Olympic athlete’s psychological, physiological, and physical barriers encountered due to the pandemic and subsequently …

Ulcerative Colitis, Randy Kinietz

Nursing Student Class Projects (Formerly MSN)

This poster briefly covers the most important concepts of ulcerative colitis (UC). UC is a complex disease process and the exact etiology is not yet known. Many researchers are currently looking to find the cause of the disease and treatment options that can target the exact pathophysiological process. Nurses are instrumental in the care of UC, especially in an outpatient setting. Education on medications and proper follow-up appointments are the key to maintaining remission, reducing flare-ups, and cancer screening. Although UC is a complex disease, a multidisciplinary approach will reduce complications and prolong remission.

Physiological Stability During Oral Feeding In Preterm Infants: Associations With Feeding Behaviors And Cues, Cindy M. Lund

Graduate Research Theses & Dissertations

The purpose of this study was to examine the relationship between measures of physiological stability/instability during feeding. An additional aim was to determine if behaviors associated with physiological stability were also perceived as readiness or stress cues. Participants included 5 preterm infants (<37 weeks gestation) with no craniofacial anomalies. Infants were videotaped when they were taking at least 90% of prescribed volume. This study analyzed the common behaviors seen in preterm infants during bottle feeding to determine if there were associations with measures of physiological stability. Behaviors were also analyzed to determine which were perceived as indicating stress or readiness to feed by novice observers. Coding was conducted offline using Noldus Observer software.

Results revealed a statistically significant relationship between behaviors classified as stress cues and HR instability. There was not a significant association between stress cues and RR or SPO2. Binomial testing identified specific preterm infant feeding behaviors that were more often classified as stress cues, with significance noted in audible swallow and vocalization. Several of the specific preterm …

The Effects Of Nutritional Aids On Exercise Performance In A Fed State, Simon Devenney

Masters

Previous research has shown that mouth rinsing with a carbohydrate solution (CMR) can improve cycling performance while caffeine supplementation (CAFF) can improve power output in bouts of repeated sprints in a low carbohydrate availability state. The aim of the current thesis was to identify the effects of nutritional, in the form of CMR, CAFF supplementation & CAFF rinse, on exercise performance while athletes were in a fed state. A total of 32 recreationally active males (aged 22 ± 3yrs, body mass 71.5 ± 10.1kg, stature 173.5 ± 7.6cm, skinfolds 75.6 ± 19.3mm) participated across three studies, looking at time trial …

Impact Of 17-Beta Estradiol And Moderate-Intensity Exercise On Mesenteric Arterial Function Of Uc Davis Type-2 Diabetes Mellitus Rats, Md Rahatullah Razan

University of the Pacific Theses and Dissertations

The studies in this dissertation were designed to investigate the impacts of estrogen (17-β estradiol/E2) and moderate-intensity exercise (MIE) on the mesenteric arterial (MA) function of the University of California Davis type-2 diabetes mellitus (UCD-T2DM) Rat model. Our recent report suggests that diabetes impairs MA vasorelaxation in both sexes of the UCD-T2DM model. Particularly, we reported that MA from prediabetic male rats showed a greater impairment compared to that in prediabetic females. However, when females become diabetic, they exhibit a greater vascular dysfunction than males. Therefore, the aim of the first study was to investigate whether female sex hormone, specifically …

The Role Of Psychological Distress In Maintaining Exercise After Cancer Diagnosis, Patrick Tertulien

Walden Dissertations and Doctoral Studies

AbstractCancer affects the lives of thousands of people every day and is a leading cause of death. Exercise has been shown to yield mental and physical benefits for patients and survivors, but the experiences of cancer patients who face a multiplicity of psychological stressors have not been clearly described. The purpose of this qualitative study was to understand the psychological factors that are associated with continuing to exercise after cancer diagnosis, during and/or following their treatment. The focus was on how cancer survivors maintained a regular routine of exercise while experiencing psychological distress associated with cancer diagnosis, treatment, and concerns …

Physiological Measurements For Real-Time Fatigue Monitoring In Train Drivers: Review Of The State Of The Art And Reframing The Problem, Bojana Bjegojevic, Maria Chiara Leva, Nora Balfe, Sam D. Cromie, Luca Longo

Conference papers

The impact of fatigue on train drivers is one of the most important safety-critical issues in rail. It affects drivers’ performance, significantly contributing to railway incidents and accidents. To address the issue of real-time fatigue detection in drivers, most reliable and applicable psychophysiological indicators of fatigue need to be identified. Hence, this paper aims to examine and present the current state of the art in physiological measures for real-time fatigue monitoring that could be applied in the train driving context. Three groups of such measures are identified: EEG, eye-tracking and heart-rate measures. This is the first paper to provide the …

Viability Of Physiologically Timed Relaxation Interventions In Children With Asd, Nicholas Mendez

CMC Senior Theses

Autism Spectrum Disorder (ASD) is an increasingly common developmental disorder that changes how people experience the world and affects individuals’ social interactions and often leads to many adverse behaviors. Current literature dictates that a primary contributor to these adverse behaviors is that those with ASD have difficulty determining their own emotional states and determining the physiological signals that their body sends them. A study by Dr. Sarabadani et al. determined that it was possible to monitor the physiology of an individual with ASD and correlate certain signals to emotions, such as stress. These findings indicate the feasibility of establishing a …

Biological System Energy Algorithm Reflected In Sub-System Joint Work Distribution Movement Strategies: Influence Of Strength And Eccentric Loading, Jeffrey M. Mcbride, Sophia Nimphius

Research outputs 2014 to 2021

© 2020, The Author(s). To better understand and define energy algorithms during physical activity as it relates to strength and movement strategy of the hip, knee and ankle, a model of increasing eccentric load was implemented in the current investigation utilizing a countermovement jump and a series of drop jumps from different heights (15, 30, 45, 60, 75 cm). Twenty-one participants were grouped by sex (men, n = 9; women, n = 12) and muscle strength (higher strength, n = 7; moderate strength, n = 7; lower strength, n = 7) as determined by a maximal squat test. Force plates …

Plasma Resuscitation Attenuates Intestinal Barrier Disturbance Following Hemorrhagic Shock., Jessica E. Schucht

Electronic Theses and Dissertations

Background: Intestinal ischemia-reperfusion injury (IIRI) following resuscitated hemorrhagic shock (HS/RES) leads to endothelial damage, microcirculatory dysfunction and intestinal barrier breakdown, increasing intestinal permeability. This pathologic process contributes pathophysiology of multiple organ dysfunction syndrome (MODS) in some trauma patients. Although vascular smooth muscle machinery remains intact, microvascular vasoconstriction occurs secondary to endothelial cell damage, resulting in further ischemia and organ injury. Used separately, resuscitation with Fresh Frozen Plasma (FFP) or Direct Peritoneal Resuscitation (DPR) improves the intestinal microcirculation and alleviates organ injury. Further examination of these effects individually or combined could aid in the resuscitation of hemorrhagic shock. Methods: Sprague Dawley …

Commentary: Physiological And Psychological Impact Of Face Mask Usage During The Covid-19 Pandemic, Jennifer Scheid, Shannon Lupien, Gregory Scott Ford, Sarah West

Articles & Book Chapters

In this commentary, we discuss the physiological effects of wearing masks for prolonged periods of time, including special considerations, such as mask wearing among those who engage in exercise training, and concerns for individuals with pre-existing chronic diseases. In healthy populations, wearing a mask does not appear to cause any harmful physiological alterations, and the potentially life-saving benefits of wearing face masks seem to outweigh the documented discomforts (e.g. headaches). However, there continues to be controversy over mask wearing in the United States, even though wearing a mask appears to have only minor physiological drawbacks. While there are minimal physiological …

Encoding The Odor Of Cigarette Smoke, Timothy S. Mcclintock, Naazneen Khan, Yelena Alimova, Madeline Aulisio, Dong Y. Han, Patrick Breheny

Physiology Faculty Publications

The encoding of odors is believed to begin as a combinatorial code consisting of distinct patterns of responses from odorant receptors (ORs), trace-amine associated receptors (TAARs), or both. To determine how specific response patterns arise requires detecting patterns in vivo and understanding how the components of an odor, which are nearly always mixtures of odorants, give rise to parts of the pattern. Cigarette smoke, a common and clinically relevant odor consisting of > 400 odorants, evokes responses from 144 ORs and 3 TAARs in freely behaving male and female mice, the first example of in vivo responses of both ORs and …

Advancing Human Health In The Decade Ahead: Pregnancy As A Key Window For Discovery: A Burroughs Wellcome Fund Pregnancy Think Tank., Yoel Sadovsky, Sam Mesiano, Graham J Burton, Michelle Lampl, Jeffrey C Murray, Rachel M Freathy, Anita Mahadevan-Jansen, Ashley Moffett, Nathan D Price, Paul H Wise, Derek E Wildman, Ralph Snyderman, Nigel Paneth, John Anthony Capra, Marcelo A Nobrega, Yaacov Barak, Louis J Muglia

Articles, Abstracts, and Reports

Recent revolutionary advances at the intersection of medicine, omics, data sciences, computing, epidemiology, and related technologies inspire us to ponder their impact on health. Their potential impact is particularly germane to the biology of pregnancy and perinatal medicine, where limited improvement in health outcomes for women and children has remained a global challenge. We assembled a group of experts to establish a Pregnancy Think Tank to discuss a broad spectrum of major gestational disorders and adverse pregnancy outcomes that affect maternal-infant lifelong health and should serve as targets for leveraging the many recent advances. This report reflects avenues for future …

Genome Diversity And The Origin Of The Arabian Horse, Elissa J. Cosgrove, Raheleh Sadeghi, Florencia Schlamp, Heather M. Holl, Mohammad Moradi-Shahrbabak, Seyed Reza Miraei-Ashtiani, Salma Abdalla, Ben Shykind, Mats H. T. Troedsson, Monika Stefaniuk-Szmukier, Anil Prabhu, Stefania Bucca, Monika Bugno-Poniewierska, Barbara Wallner, Joel Malek, Donald C. Miller, Andrew G. Clark, Douglas F. Antczak, Samantha A. Brooks

Veterinary Science Faculty Publications

The Arabian horse, one of the world's oldest breeds of any domesticated animal, is characterized by natural beauty, graceful movement, athletic endurance, and, as a result of its development in the arid Middle East, the ability to thrive in a hot, dry environment. Here we studied 378 Arabian horses from 12 countries using equine single nucleotide polymorphism (SNP) arrays and whole-genome re-sequencing to examine hypotheses about genomic diversity, population structure, and the relationship of the Arabian to other horse breeds. We identified a high degree of genetic variation and complex ancestry in Arabian horses from the Middle East region. Also, …