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Articles 31 - 60 of 100
Full-Text Articles in Medicine and Health Sciences
The Impact Of Free Health Screenings At Community Pharmacies On Diabetes, Jeb Ballentine, Emily M. Laswell, Anna M. Staudt, Jacques N. Allou, Jeniffer George, Jessica E. Amtower, Nicholas C. Daniels
The Impact Of Free Health Screenings At Community Pharmacies On Diabetes, Jeb Ballentine, Emily M. Laswell, Anna M. Staudt, Jacques N. Allou, Jeniffer George, Jessica E. Amtower, Nicholas C. Daniels
Anna Staudt, Pharm.D.
Diabetes is a prevalent issue in the United States, with an estimated 8.1 million people un-diagnosed as of 2012. Health screenings have been proven to identify diseases earlier, thereby resulting in earlier and more satisfactory treatment. Community pharmacies can offer many of the same screenings as those in doctor offices. The objective of this study was to assess the impact of free health screenings in community pharmacies on patient follow-up, perceptions, and knowledge of diabetes through blood glucose screenings and patient education. The study design was a pre-post observational study using surveys, blood sugar screenings, and patient education on diabetes. …
Pursuing Equity In Diabetes Population, Aisha Rawlinson
Pursuing Equity In Diabetes Population, Aisha Rawlinson
Master's Projects and Capstones
Abstract
Background
Poor glycemic control (HbA1c >8) overtime leads to microvascular and macrovascular complications after the first and third years respectively, ultimately resulting in death after five years (Karter, 2016). Current Kaiser Permanente (KP) data stratified by race, ethnicity, age, and gender shows a significant disparity gap between Hispanics/Latino and Caucasian populations. The Pursuing IHI initiative is over a 2-year period completed at a microsystem that is focusing on health equity practices to reduce disparity gaps.
Project aim
KP Riverside, microsystem selected has a large population of Hispanic/Latino KP members, with focus on health equity. The project aim is to …
Dmt For T1d: Using Dance/Movement Therapy To Facilitate Coping, Self-Awareness, And Positive Body Image In Adolescents With Type I Diabetes, Nicole L. Williams-Mulet
Dmt For T1d: Using Dance/Movement Therapy To Facilitate Coping, Self-Awareness, And Positive Body Image In Adolescents With Type I Diabetes, Nicole L. Williams-Mulet
Dance/Movement Therapy Theses
This paper explores type 1 diabetes (T1D) and the risk factors associated from its diagnosis. In particular, this paper addresses the onset of T1D in adolescence, which is a developmental period riddled with its own challenges. T1D is a chronic, autoimmune disease that affects the body’s ability to produce insulin. Unregulated, T1D affects the body in numerous ways and can ultimately lead to death. Research has suggested that children diagnosed with T1D should employ an integrated treatment team to account for the physical and emotional struggles that come from living with the disease. Dance/movement therapy (DMT) is a form of …
Diabetes In Sub-Saharan Africa: From Clinical Care To Health Policy., Rifat Atun, Justine I. Davies, Edwin A.M. Gal, Till Bärnighausen, David Beran, Andre Pascal Kengne, Naomi S. Levitt, Florence Mangugu, Moffat J. Nyirenda, Graham D. Ogle, Kaushik Ramaiya
Diabetes In Sub-Saharan Africa: From Clinical Care To Health Policy., Rifat Atun, Justine I. Davies, Edwin A.M. Gal, Till Bärnighausen, David Beran, Andre Pascal Kengne, Naomi S. Levitt, Florence Mangugu, Moffat J. Nyirenda, Graham D. Ogle, Kaushik Ramaiya
Paediatrics and Child Health, East Africa
Rapid demographic, sociocultural, and economic transitions are driving increases in the risk and prevalence of diabetes and other non-communicable diseases (NCDs) in sub-Saharan Africa. The impacts of these transitions and their health and economic consequences are evident. Whereas, in 1990, the leading causes of death in sub-Saharan Africa were HIV/AIDS, lower respiratory infections, diarrhoeal diseases, malaria, and vaccine-preventable diseases in children, in more recent years, cardiovascular diseases and their risk factors are replacing infectious diseases as the leading causes of death in this region, and rates of increase of cardiovascular risk factors are predicted to be greater in sub-Saharan Africa …
Application Of Support Vector Machine Modeling And Graph Theory Metrics For Disease Classification, Jessica M. Rudd
Application Of Support Vector Machine Modeling And Graph Theory Metrics For Disease Classification, Jessica M. Rudd
Published and Grey Literature from PhD Candidates
Disease classification is a crucial element of biomedical research. Recent studies have demonstrated that machine learning techniques, such as Support Vector Machine (SVM) modeling, produce similar or improved predictive capabilities in comparison to the traditional method of Logistic Regression. In addition, it has been found that social network metrics can provide useful predictive information for disease modeling. In this study, we combine simulated social network metrics with SVM to predict diabetes in a sample of data from the Behavioral Risk Factor Surveillance System. In this dataset, Logistic Regression outperformed SVM with ROC index of 81.8 and 81.7 for models with …
Interprofessional Collaboration To Support Children With Diabetes, Katie M. Polo, Susan M. Cahill
Interprofessional Collaboration To Support Children With Diabetes, Katie M. Polo, Susan M. Cahill
The Open Journal of Occupational Therapy
Background: The purpose of this study was to investigate school nurses’ perspectives related to interprofessional collaboration to support health promotion and development of self-management skills of students with diabetes.
Method: A link to an on-line survey was sent to 312 school nurses. The survey included 11 items pertaining to the nurses’ perceptions.
Results: The majority of the respondents (91.8%, n = 56) reported that instruction and maintenance of diabetes self-management skills would benefit from an interprofessional team. Few of the respondents (20.8%, n = 11) identified occupational therapy practitioners as possible collaborators. Nearly two-thirds (62.7%, n = 37) of the …
Partnership Between Academic And Public Health To Train Public Health Nurses New Chronic Diseases Protocols, Kathryn Martin, Elena Wood, Stephen Goggans, Anthony Mulloy, Shilpa Brown, Paul Wallach
Partnership Between Academic And Public Health To Train Public Health Nurses New Chronic Diseases Protocols, Kathryn Martin, Elena Wood, Stephen Goggans, Anthony Mulloy, Shilpa Brown, Paul Wallach
Journal of the Georgia Public Health Association
Background: According to the Georgia Department of Public Health (DPH), cardiovascular disease is the leading cause of death in Georgia (29% in 2013). Diabetes (DM) and hypertension (HTN) are known risk factors for cardiovascular disease. In 2013, the prevalence of diabetes was 11% and of hypertension was 35% of the state’s adult population. There are not sufficient healthcare providers to manage these patients. To address this concern, the DPH Chronic Disease Prevention Section contracted with the Medical College of Georgia (MCG) at Augusta University to design and implement an innovative training program for Georgia public health nurses on diabetes and …
The Effect Of Vitamin D3 Supplementation On Kidney Function And Cardiovascular Disease Markers Among Hispanics And African Americans With Type 2 Diabetes, Gustavo G. Zarini
The Effect Of Vitamin D3 Supplementation On Kidney Function And Cardiovascular Disease Markers Among Hispanics And African Americans With Type 2 Diabetes, Gustavo G. Zarini
FIU Electronic Theses and Dissertations
Serum vitamin D deficiency/insufficiency, Chronic Kidney Disease (CKD) and elevated blood pressure are important health concerns especially among minorities with type 2 diabetes. The effect of vitamin D3 supplementation (cholecalciferol) at 6,000 IU/day (d) vs. 4,000 IU/d on kidney function and cardiovascular disease markers among Hispanics and African Americans with type 2 diabetes and hypovitaminosis D (/ml) was evaluated. Subjects (n=63) were recruited from two clinics in Miami-Dade County, FL. Fasting venous blood and fresh, single-voided first morning urine samples were collected from each participant by a certified phlebotomist and analyzed by Solstas Lab Partners, Davie, FL. Linear mixed …
Sex After Gray Hair? Association Between Sexual Activity, Hugging, And Health Among Older Adults?, Chantelle Sharpe
Sex After Gray Hair? Association Between Sexual Activity, Hugging, And Health Among Older Adults?, Chantelle Sharpe
USF Tampa Graduate Theses and Dissertations
Research on sexual behavior in late life is limited but is growing. Despite ageist stereotypes associating old age with asexuality, older adults continue to desire and engage in sexual behavior. Previous studies have examined the relationship between health and the ability to engage in sexual behavior, sexual satisfaction, desire, or interest in sex. Research has yet to examine the potential reverse of this relationship, where sexual behavior may serve as a protective factor against health outcomes.
This dissertation examined three research questions to test the relationship between sexual activity or hugging and self-reported health outcomes (e.g., arthritis and diabetes) and …
Occupational Stress And Increased Risk For Type 2-Diabetes: A Narrative Review, Harrynauth Persaud, Shawn Williams
Occupational Stress And Increased Risk For Type 2-Diabetes: A Narrative Review, Harrynauth Persaud, Shawn Williams
Publications and Research
Diabetes is a significant health problem in the United States. There is a large body of research that explains the biological and pathoetiological cause(s) of this increasingly prevalent disease. There is also an increasing body of research that explores the psychosocial causes of diabetes mellitus type 2. The association between stressful work organization and diabetes has been established as a significant precursor and causative agent of diabetes mellitus - type 2. The objective of this narrative review is to discuss the impact of work stress as it applies to the rising incidence of diabetes - type 2, and to propose …
Use Of Social Adaptability Index To Explain Self-Care And Diabetes Outcomes, Jennifer A. Campbell, Rebekah J. Walker, Brittany L. Smalls, Leonard E. Egede
Use Of Social Adaptability Index To Explain Self-Care And Diabetes Outcomes, Jennifer A. Campbell, Rebekah J. Walker, Brittany L. Smalls, Leonard E. Egede
Center for Health Services Research Faculty Publications
Background: To examine whether the social adaptability index (SAI) alone or components of the index provide a better explanatory model for self-care and diabetes outcomes.
Methods: Six hundred fifteen patients were recruited from two primary care settings. A series of multiple linear regression models were run to assess (1) associations between the SAI and diabetes self-care/outcomes, and (2) associations between individual SAI indicator variables and diabetes self-care/outcomes. Separate models were run for each self-care behavior and outcome. Two models were run for each dependent variable to compare associations with the SAI and components of the index.
Results: The SAI has …
Diabetes Screening And Prevention In A High-Risk, Medically Isolated Border Community, Ann V. Millard, Margaret A. Graham, Nelda Mier, Jesus Moralez, Maria Perez-Patron, Brian Wickwire, Marlynn L. May, Marcia G. Ory
Diabetes Screening And Prevention In A High-Risk, Medically Isolated Border Community, Ann V. Millard, Margaret A. Graham, Nelda Mier, Jesus Moralez, Maria Perez-Patron, Brian Wickwire, Marlynn L. May, Marcia G. Ory
Anthropology Faculty Publications and Presentations
Introduction: A project in a Texas border community setting, Prevention Organized against Diabetes and Dialysis with Education and Resources (POD2ER), offered diabetes prevention information, screening, and medical referrals. The setting was a large, longstanding flea market that functions as a shopping mall for low-income people. The priority population included medically underserved urban and rural Mexican Americans. Components of the program addressed those with diabetes, prediabetes, and accompanying relatives and friends.
Background: People living in the Lower Rio Grande Valley (LRGV) face challenges of high rates of type 2 diabetes, lack of knowledge about prevention, and inadequate access to medical care. …
Transitional Healthcare Coordination In New York City Jails Among People With Chronic Health Conditions: Contributions To Reduced Reincarceration And Improved Health, Janet J. Wiersema
Transitional Healthcare Coordination In New York City Jails Among People With Chronic Health Conditions: Contributions To Reduced Reincarceration And Improved Health, Janet J. Wiersema
Dissertations and Theses
People in correctional settings often have poorer health than the general US population. For example, it is estimated that 27.9% of persons in jail have hypertension, 8.1% have diabetes, and 1.6% have HIV, compared to 25.6%, 6.5%, and 0.5%, respectively, in the general population. Jail and other correctional settings are also increasingly recognized as viable places to engage poor and underserved communities into the healthcare system by offering transitional care coordination services to connect people to healthcare and other services to meet priorities after incarceration. At the same time, recidivism is an issue—over 50% of persons in New York City …
Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi
Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and non-ketotic hyperosmolar coma. In addition, possible long-term complications include impotence, nerve damage, stroke, chronic kidney failure, cardiovascular disease, foot ulcers, and retinopathy. Historically, universal methods to measure glycemic control for the diagnosis of diabetes included fasting plasma glucose level (FPG), 2-h plasma glucose (2HP), and random plasma glucose. However, these measurements did not provide information about glycemic control over a long period of time. To …
Implementing An Emr Change For The Diabetic Foot Assessment, Nicole O'Neil, Karen Sue Hoyt
Implementing An Emr Change For The Diabetic Foot Assessment, Nicole O'Neil, Karen Sue Hoyt
Doctor of Nursing Practice Final Manuscripts
The purpose of this project was to implement the American Diabetes Association (ADA) foot assessment guidelines utilizing an electronic medical record (EMR) template. Aims of this evidence based practice (EBP) project were to improve documentation of the comprehensive diabetic foot exam, increase identification of loss of protective sensation (LOPS), and increase podiatry and vascular surgery referrals. Diabetes Mellitus (DM) causes many health complications. The lifetime risk of foot ulceration in diabetic patients is 25%. The goal of Healthy People 2020 is to increase this number by 10% to a total of 21,617,200 individuals. The ADA recommends annual comprehensive foot exam …
Activity Trackers: Are They The Answer, Connor Ogden, Neil Peterson
Activity Trackers: Are They The Answer, Connor Ogden, Neil Peterson
Journal of Undergraduate Research
Physical inactivity in young adults leads to a 40% greater chance of cancer mortality, 50% greater risk of dementia, 60% greater risk of stroke, type 2 diabetes, obesity, and a number of other health related issues1. In our country in which sedentary jobs have increased by 83% since 1950, and 69%2 of all adults are obese or overweight, these health related factors due to inactivity become a real concern. Many companies have created these activity trackers as a solution to solving physical inactivity. The purpose of this project was to evaluate what aspects of the Microsoft Band that young adults …
Vitamin D Status And Demographic And Lifestyle Determinants Among Adults In The United States (Nhanes 2001-2006), Yan Cao, Katie L. Callahan, Sreenivas P. Veeranki, Yang Chen, Ying Liu, Shimin Zheng
Vitamin D Status And Demographic And Lifestyle Determinants Among Adults In The United States (Nhanes 2001-2006), Yan Cao, Katie L. Callahan, Sreenivas P. Veeranki, Yang Chen, Ying Liu, Shimin Zheng
Shimin Zheng
This study looked at risk factors associated with vitamin D levels in the body among a representative sample of adults in the U.S., NHANES III (2001-2006) data were used to assess the relationship between several demographic and health risk factors and vitamin D levels in the body. The Baseline-Category Logit Model was used to test the association between vitamin D level and the potential risk factors age, education, ethnicity, poverty status, physical activity, smoking, alcohol, obesity, diabetes and total cholesterol with both genders. Vitamin D insufficiency and deficiency were significantly associated with age, race, education, physical activity, obesity, diabetes and …
The Turnover Of Succinated Proteins In The Adipocyte For The Treatment Of Diabetes, Dominique Jacobs
The Turnover Of Succinated Proteins In The Adipocyte For The Treatment Of Diabetes, Dominique Jacobs
Senior Theses
In the United States 29.1 million people have diabetes, or 1 out of every 11 people. The rate of new cases of diagnosed diabetes has begun to fall, but the numbers are still very high. 86 million people are living with prediabetes, a serious health condition that increases a person’s risk of developing type 2 diabetes mellitus (T2DM) and other chronic diseases (1). Unfortunately, 90% of those 86 million people are unaware that they are at risk. The health and economic costs for both types of diabetes are enormous: more than 20% of health care spending is committed to people …
Effects Of Individualized Health Coaching In Patients With Type 2 Diabetes, Stephanie Gill, Emily Nilson
Effects Of Individualized Health Coaching In Patients With Type 2 Diabetes, Stephanie Gill, Emily Nilson
Physician Assistant Capstones, 2016 to 2019
Objective: To conduct an analysis of literature that examined the effects of individualized health coaching on hemoglobin A1c in adults with type 2 diabetes. Methods: A literature search of the PubMed database using the terms “goal setting” AND type 2 diabetes OR “individual counseling” was performed. Only randomized controlled trials and meta-analysis were included. Results: All three studies reported a statistically significant difference in lowering hemoglobin A1c levels with individualized health coaching interventions compared to the standard diabetes interventions. Conclusion: Health coaching should be further studied for longer amounts of time to determine the true clinical significance of lowering …
An Assessment Of The Associate Degree Nursing Students’ Understanding Of Health Literacy Concepts When Providing Health Promotion For The Diabetic Patient, Donna L. Lebaron
An Assessment Of The Associate Degree Nursing Students’ Understanding Of Health Literacy Concepts When Providing Health Promotion For The Diabetic Patient, Donna L. Lebaron
Doctoral Projects
Health literacy (HL) concept deficiencies exist in undergraduate nursing curricula (Smith and Zsohar, 2011; Cornett, 2009; Jukkala, Deupree, Graham, 2009). As future nurses who will have a significant impact on client health literacy assessment, it is essential that health literacy-related content be integrated into undergraduate nursing educational curricula (Sand-Jecklin, Murray, Summers, Watson, 2010; McCleary-Jones, 2012). The prevalence of Type 2 diabetes (T2D) has significantly increased resulting in greater morbidity and mortality risks to the general public; therefore, programs for diabetes prevention, education, and health literacy assessments have become a national priority (Whittemore, Rosenberg, Gilmore, Withey, and Breault, 2013; Hemingway, Stephenson, …
The Effects Of An Acute Bout Of Exercise On Hunger Hormones In Individuals At Risk For Type 2 Diabetes, Sydney Spoon
The Effects Of An Acute Bout Of Exercise On Hunger Hormones In Individuals At Risk For Type 2 Diabetes, Sydney Spoon
UNLV Theses, Dissertations, Professional Papers, and Capstones
Background: Hunger hormone levels are typically dysregulated in obese and diabetic
populations, however; postprandial exercise has been shown to influence hunger hormone levels. Purpose: To determine if hunger hormones including acylated ghrelin and GLP-1 levels are altered in response to an acute bout (15 minutes) of walking in individuals at risk for type 2 diabetes mellitus (T2DM).
Methods: Ten subjects at risk for prediabetes (fasting blood glucose 100–125mg/dL) participated in this randomized crossover design trial. Subjects arrived at the laboratory following an overnight fast and underwent one of two conditions: 1) Test meal with no walking (CON) or 2) Test …
An Evaluation Of Gabab Receptors On Modulating Neuroinflammation In A Non-Transgenic Animal Model Of Alzheimer's Disease, Monica Bolton
An Evaluation Of Gabab Receptors On Modulating Neuroinflammation In A Non-Transgenic Animal Model Of Alzheimer's Disease, Monica Bolton
UNLV Theses, Dissertations, Professional Papers, and Capstones
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and distinct neuropathological hallmarks, including amyloid beta plaques and neurofibrillary tau tangles (NFT). Although the etiology remains to be discovered, several risk factors exist that significantly contribute to developing AD. Diabetes is one of the major risk factors associated with AD and is characterized by disrupted insulin signaling that may contribute to or exacerbate AD pathologies. Furthermore, both disorders result in increased neuroinflammation. Considerable evidence has demonstrated that a chronic inflammatory response, in particular chronic microglia activation, promotes A production as well as the hyperphosphorylation of tau through …
The Correlation Of Free Health Screenings At Community Pharmacies On Diabetes, Anna M. Staudt, Jessica E. Amtower, Jeniffer George, Nicholas C. Daniels, Jacques N. Allou, Emily M. Laswell, Jeb Ballentine
The Correlation Of Free Health Screenings At Community Pharmacies On Diabetes, Anna M. Staudt, Jessica E. Amtower, Jeniffer George, Nicholas C. Daniels, Jacques N. Allou, Emily M. Laswell, Jeb Ballentine
Pharmacy Practice Faculty Publications
No abstract provided.
A1c Reduction And Weight Loss In A Veteran Population Using Glp-1-Ras, Shelby L. Beutel Darrow
A1c Reduction And Weight Loss In A Veteran Population Using Glp-1-Ras, Shelby L. Beutel Darrow
Undergraduate Honors Thesis Collection
Background: Diabetes mellitus is a metabolic disorder defined by high blood glucose. Glucagon-like peptide-1 receptor agonists (GLP-1-RAs) are a newer class of medications that offer potential 2 to 3 kg weight loss and a 1% to 1.5% decrease in A1c. At the Indianapolis Veterans Affairs Medical Center (VAMC), GLP-1-RAs are non-formulary.
Objectives: Primary outcomes included mean change in weight, body mass index (BMI) and A1c in VAMC patients. Secondary outcomes included the comparison to published values, analysis of insulin needs, and analysis of GLP-1-RA discontinuation reasons.
Methods: Indianapolis VAMC patients ages 18-80 with type 2 diabetes who started a GLP-1-RA …
Health & Kinesiology News, Georgia Southern University
Health & Kinesiology News, Georgia Southern University
Health and Kinesiology, Department of - News (2015-2023)
- Students provide Healthy and Diabetes Friendly Food Demonstrations
Diabetes, Cardiovascular Disease, And Chronic Kidney Disease In South Asia: Current Status And Future Directions, Anoop Misra, Nikhil Tandon, Shah Ebrahim, Naveed Sattar, Dewan Alam, Usha Shrivastava, K M Venkat Narayan, Tazeen H. Jafar
Diabetes, Cardiovascular Disease, And Chronic Kidney Disease In South Asia: Current Status And Future Directions, Anoop Misra, Nikhil Tandon, Shah Ebrahim, Naveed Sattar, Dewan Alam, Usha Shrivastava, K M Venkat Narayan, Tazeen H. Jafar
Section of Pulmonary & Critical Care
No abstract provided.
Clinical Significance Of A False Positive Glucose Challenge Test In Patients With A High Body Mass Index, A Borja, M Moretti, Nisha Lakhi
Clinical Significance Of A False Positive Glucose Challenge Test In Patients With A High Body Mass Index, A Borja, M Moretti, Nisha Lakhi
NYMC Faculty Publications
OBJECTIVE: To determine if there is an increased maternal or neonatal morbidity in overweight and obese patients with a false positive glucose challenge test (GCT). METHODS: Patients with a body mass index (BMI) >/=25.0 at registration were included in this prospective 36-month study. The study cohort consisted of patients with a false positive (FP) GCT, with two comparison cohorts: those with a (1) screen negative (SN) GCT result and (2) true positive (TP) GCT result. Risks were reported as odd ratios with 95% confidence intervals, with a P/=4000 g in the FP cohort, but this fell short of reaching statistical …
Comparison Of Multiple Obesity Indices For Cardiovascular Disease Risk Classification In South Asian Adults: The Carrs Study., Shivani A. Patel, Mohan Deepa, Roopa Shivashankar, Mohammed K. Ali, Deksha Kapoor, Ruby Gupta, Dorothy Lall, Nikhil Tandon, Viswanathan Mohan, Muhammad Masood Kadir, Zafar Fatmi, Dorairaj Prabhakaran, K. M. Venkat Narayan
Comparison Of Multiple Obesity Indices For Cardiovascular Disease Risk Classification In South Asian Adults: The Carrs Study., Shivani A. Patel, Mohan Deepa, Roopa Shivashankar, Mohammed K. Ali, Deksha Kapoor, Ruby Gupta, Dorothy Lall, Nikhil Tandon, Viswanathan Mohan, Muhammad Masood Kadir, Zafar Fatmi, Dorairaj Prabhakaran, K. M. Venkat Narayan
Community Health Sciences
BACKGROUND:
We comparatively assessed the performance of six simple obesity indices to identify adults with cardiovascular disease (CVD) risk factors in a diverse and contemporary South Asian population.
METHODS:
8,892 participants aged 20-60 years in 2010-2011 were analyzed. Six obesity indices were examined: body mass index (BMI), waist circumference (WC), waist-height ratio (WHtR), waist-hip ratio (WHR), log of the sum of triceps and subscapular skin fold thickness (LTS), and percent body fat derived from bioelectric impedance analysis (BIA). We estimated models with obesity indices specified as deciles and as continuous linear variables to predict prevalent hypertension, diabetes, and high cholesterol …
Use Of Grounded Theory In Cardiovascular Research, Patrick J. Dunn, Vasileios Margaritis, Cheryl Anderson
Use Of Grounded Theory In Cardiovascular Research, Patrick J. Dunn, Vasileios Margaritis, Cheryl Anderson
The Qualitative Report
While grounded theory is often cited in the qualitative literature as the methodology, there are few good examples of publications that follow the principles of grounded theory and result in an actual theory. The purpose of this paper is to demonstrate how the Corbin and Strauss (2015) method of grounded theory was used in a study looking at how patients with cardiovascular disease and diabetes develop health literacy skills that are used to manage their condition. The key principles of grounded theory include theoretical sampling, constant comparison, open, axial, and selective coding, the use of memoing, and theoretical saturation. Data …
Structure-Activity And In Vivo Evaluation Of A Novel Lipoprotein Lipase (Lpl) Activator, Werner J. Geldenhuys, Joel Caporoso, Thomas C. Leeper, Yoon-Kwang Lee, Li Lin, Altaf S. Darvesh, Prabodh Sadana
Structure-Activity And In Vivo Evaluation Of A Novel Lipoprotein Lipase (Lpl) Activator, Werner J. Geldenhuys, Joel Caporoso, Thomas C. Leeper, Yoon-Kwang Lee, Li Lin, Altaf S. Darvesh, Prabodh Sadana
Clinical and Translational Science Institute
Elevated triglycerides (TG) contribute towards increased risk for cardiovascular disease. Lipoprotein lipase (LPL) is an enzyme that is responsible for the metabolism of core triglycerides of very-low density lipoproteins (VLDL) and chylomicrons in the vasculature. In this study, we explored the structure-activity relationships of our lead compound (C10d) that we have previously identified as an LPL agonist. We found that the cyclopropyl moiety of C10d is not absolutely necessary for LPL activity. Several substitutions were found to result in loss of LPL activity. The compound C10d was also tested in vivo for its lipid lowering activity. Mice were fed a …