Medicine and Health Sciences Commons^™

Measuring Attentional Ability In Older Adults: Development And Psychometric Evaluation Of Driverscan, Lesa Hoffman, Yang Xiangdong, James A. Bovaird, Susan E. Embretson

Department of Psychology: Faculty Publications

Although deficits in visual attention are often postulated as an important component of many declines in cognitive processing and functional outcomes in older adults, surprisingly little emphasis has been placed on evaluating psychometric instruments with which individual differences in visual attention ability can be assessed. This article reports the development and beginning psychometric evaluation of DriverScan, a change detection measure of attentional search for older adults. A constrained graded response model is used to approximate response speed and accuracy with categories of immediate, delayed, or no response. DriverScan items are shown to have excellent reliability over the studied sample, and …

Transfusion-Associated Transmission Of West Nile Virus, United States 2003 Through 2005, Susan P. Montgomery, Jennifer A. Brown, Matthew Kuehnert, Theresa L. Smith, Nicholas Crall, Robert S. Lanciotti, Alexandre Macedo De Oliveira, Thomas Boo, Anthony A. Marfin, 2003 West Nile Virus Transfusion-Associated Transmission Investigation Team

Public Health Resources

BACKGROUND: National blood donation screening for West Nile virus (WNV) started in June 2003, after the documentation of WNV transfusion-associated transmission (TAT) in 2002.
STUDY DESIGN AND METHODS: Blood donations were screened with investigational nucleic acid amplification assays in minipool formats. Blood collection agencies (BCAs) reported screening results to state and local public health authorities. Donor test results and demographic information were forwarded to CDC via ArboNET, the national electronic arbovirus surveillance system. State health departments and BCAs also reported suspect WNV TATs to CDC, which investigated these reports to confirm WNV infection in blood transfusion recipients in the absence …

Antibiotic Susceptibility Of Atopobium Vaginae, Ellen De Backer, Rita Verhelst, Hans Verstraelen, Geert Claeys, Gerda Verschraegen, Marleen Temmerman, Mario Vaneechoutte

Obstetrics and Gynaecology, East Africa

Background: Previous studies have indicated that a recently described anaerobic bacterium, Atopobium vaginae is associated with bacterial vaginosis (BV). Thus far the four isolates of this fastidious micro-organism were found to be highly resistant to metronidazole and susceptible for clindamycin, two antibiotics preferred for the treatment of BV.

Methods: Nine strains of Atopobium vaginae, four strains of Gardnerella vaginalis, two strains of Lactobacillus iners and one strain each of Bifidobacterium breve, B. longum, L. crispatus, L. gasseri and L. jensenii were tested against 15 antimicrobial agents using the Etest.

Results: All nine strains of A. vaginae were highly resistant to …

Sensory Integration: It's Not Just For Children, Renee Watling, Stefanie Bodison, Diana A. Henry, Heather Miller-Kuhaneck

Occupational Therapy Faculty Publications

Sensory integration theory and intervention techniques were originally developed by A. Jean Ayres, PhD, OTR, beginning in the late 1960s. Her pioneering work integrated scientific information from neuroscience, psychology, occupational therapy, and human development in an effort to help explain the relationship among experience, brain development, and function. Ayres's theory of sensory integration provides a solid foundation for understanding the impact of sensation on occupational performance across the life span. Although much of the existing work related to sensory integration addresses occupational performance issues in children, some believe the theory and framework to be important across the life span. However, …

Transfusion-Associated Transmission Of West Nile Virus, United States 2003 Through 2005, Susan P. Montgomery, Jennifer A. Brown, Matthew Kuehnert, Theresa L. Smith, Nicholas Crall, Robert S. Lanciotti, Alexandre Macedo De Oliveira, Thomas Boo, Anthony A. Marfin, 2003 West Nile Virus Transfusion-Associated Transmission Investigation Team

Zoonotics and Wildlife Disease: Publications

BACKGROUND: National blood donation screening for West Nile virus (WNV) started in June 2003, after the documentation of WNV transfusion-associated transmission (TAT) in 2002.

STUDY DESIGN AND METHODS: Blood donations were screened with investigational nucleic acid amplification assays in minipool formats. Blood collection agencies (BCAs) reported screening results to state and local public health authorities. Donor test results and demographic information were forwarded to CDC via ArboNET, the national electronic arbovirus surveillance system. State health departments and BCAs also reported suspect WNV TATs to CDC, which investigated these reports to confirm WNV infection in blood transfusion recipients in the absence …

Differential Effects Of Stimulus Context In Sensory Processing: Effets Différentiels Du Contexte De Présentation Des Stimuli Sur Les Processus Perceptifs, Yoav Arieh, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

Stimulus contexts in which different intensity levels are presented to two sensory–perceptual channels can produce differential effects on perception: Perceived magnitudes are depressed in whichever channel received the stronger stimuli. Context differentially can affect loudness at different sound frequencies or perceived length of lines in different spatial orientations. Reported in the hearing, vision, haptic touch, taste, and olfaction, differential context effects (DCEs) are a general property of perceptual processing. Characterizing their functional properties and determining their underlying mechanisms are essential both to fully understanding sensory and perceptual processes and to properly interpreting sensory measurements obtained in applied as well …

The Qingdao Twin Registry: A Focus On Chronic Disease Research, C. Anderson Johnson, Zengchang Pang, Feng Ning, Jennifer B. Unger, Shaojie Wang, Qian Guo, Weihua Cao, Liming Lee

CGU Faculty Publications and Research

With the changing patterns of morbidity and mortality in China, noncommunicable chronic diseases have become the major threats to the health of the Chinese population. The causes of chronic diseases include genetic factors and behavioral risk factors such as the use of tobacco, alcohol, and other drugs, unhealthy dietary behaviors, and lack of physical activity. Twin studies offer a unique opportunity to disentangle the genetic and environmental risk and protective factors for chronic disease. The Qingdao Twin Registry (QTR) was initiated in 1998 as part of the National Chinese Twin Registry. Over 11,000 pairs of twins and multiples of all …

Clinical Registered Dietitians, Employers, And Educators Are Interested In Advanced Practice Education And Professional Doctorate Degrees In Clinical Nutrition, Annalynn Skipper, Nancy M. Lewis

Department of Nutrition and Health Sciences: Faculty Publications

A subset of registered dietitians (RDs) is known to practice at an advanced level, but a clear educational pathway supporting advanced medical nutrition therapy practice has not been identified. Thus, an electronic survey was designed to investigate interest of clinical RDs, employers, and educators in advanced practice competencies and professional doctorate degree programs in clinical nutrition. Usable responses were obtained from 440 of 978 (45%) RDs, 61 of 107 (57%) employers, and 76 of 114 (67%) educators. Mean interest (5 = very interested, 1 = very uninterested) in obtaining advanced practice education was highest among RDs (3.93 ±1.01) and was …

Clinical Viability Study Of Preattentive Visual Search Glaucoma, James Loughman

Doctoral

Background/Aim: Previous research has shown that several clinical conditions cause increased pre-attentive visual search (PAVS) times, implying reduced parallel search capabilities in glaucoma, DLB dementia and Parkinson’s disease. The purpose of the research reported here was two-fold • To examine for the first time the effect of a number of variables on PAVS performance including optical blur, age, retinal eccentricity and perceptual learning. Such investigations are designed to elucidate the nature of best clinical practise and to determine whether the test remains viable in the presence of such potentially confounding variables. • To analyse the efficiency of PAVS in cases …

Objectively Measured Physical Activity In Sixth-Grade Girls, Russell R. Pate, June Stevens, Charlotte Pratt, James F. Sallis, Kathryn H. Schmitz, Larry S. Webber, Gregory J. Welk, Deborah Rohm Young

Faculty Publications

Objectives - To describe the objectively-measured physical activity (PA) characteristics of a diverse sample of 6^th grade girls to examine influences on PA, and to report compliance with PA guidelines.

Design - Cross-sectional study.

Setting - Six locations across the United States.

Participants - 1578 6^th grade girls. Actigraph accelerometers were worn for 7 days, and data for 6 days were included in the analyses.

Main exposure - Race/ethnicity, free-or-reduced price lunch (FRPL), and geographic region.

Main outcome measure - Six operational definitions of adequate activity (60 min or 30 min of daily MVPA at or above 4.6, …

Caesarian Section Rates And Perinatal Outcome At The Aga Khan University Hospital, Nairobi, Sikolia Wanyonyi, Evan Sequeira, Timona Obura

Obstetrics and Gynaecology, East Africa

Background: There has been a persistent rise in the rate of Caesarean sections over the years.Whether this rise is the cause of the decline in infant mortality and improved neonatal outcome still remains debatable.

Objective: To compare the Caesarian section rate and the perinatal outcome at the Aga Khan University Hospital for the years 2001and 2004.

Design: Retrospective study.

Setting: The Aga Khan University Hospital, Nairobi.

Main outcome measures: The total Caesarian section rates, their indication and the perinatal outcome. Results: The overall Caesarian section rate was 20.4% in 1996,25.9% in 2001and 38.1% in 2004.The rate among patients managed by …

A Knowledge, Attitudes, And Practice Survey Among Obstetrician-Gynaecologists On Intimate Partner Violence In Flanders, Belgium, Kristien Roelens, Hans Verstraelen, Kathia Van Egmond, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: Intimate partner violence (IPV) has consistently been found to afflict one in twenty pregnant women and is therefore considered a leading cause of physical injury, mental illness and adverse pregnancy outcome. A general antenatal screening policy has been advocated, though compliance with such guidelines tends to be low. We therefore attempted to identify potential barriers to IPV screening in a context where no guidelines have been instigated yet.

Methods: Questionnaire-based Knowledge, Attitude, and Practice survey among obstetrician-gynaecologists in Flanders, Belgium (n = 478).

Results: The response rate was 52.1% (249/478). Gynaecologists prove rather unfamiliar with IPV and therefore largely …

Immediate Surgical Repositioning Following Intrusive Luxation: A Case Report And Review Of The Literature, H. Cem Güngör, S. Burcak Cengiz, Nil Altay

School of Dentistry Faculty Research and Publications

This report presents a case of severe intrusive luxation of mature maxillary lateral incisor in a 10-year-old boy. The intruded tooth was immediately repositioned (surgical extrusion) and splinted within 2 h following injury. Tetracycline therapy was initiated at the time of repositioning and maintained for 10 days. Pulp removal and calcium hydroxide treatment of the root canal was carried out after repositioning. Splint was removed 1 month later. Definitive root canal treatment with gutta percha was accomplished at the second month recall. Clinical and radiographic examination 28 months after the surgical extrusion revealed satisfactory apical and periodontal healing.

Higher Self-Reported Physical Activity Is Associated With Lower Systolic Blood Pressure: The Dietary Intervention Study In Childhood (Disc) , Samuel S. Gidding, Bruce A. Barton, Joanne A. Dorgan, Sue Y.S. Kimm, Peter O. Kwiterovich, Normal L. Lasser, Alan M. Robson, Victor J. Stevens, Linda Van Horn, Denise G. Simons-Morton

Department of Pediatrics Faculty Papers

Objective: Children participating in a dietary clinical trial were studied to assess physical activity patterns in boys and girls longitudinally from late childhood through puberty; and to determine the association of level of physical activity on systolic blood pressure (SBP), low density lipoprotein (LDL) cholesterol, and body mass index (BMI).

Patients and Methods: In the Dietary Intervention Study in Childhood (DISC), a randomized clinical trial of a reduced saturated fat and cholesterol diet in 8-10 year olds with elevated LDL, a questionnaire that determined time spent in five intensity levels of physical activity was completed at baseline and …

Evaluation Of A Telephone-Based Support Group Intervention For Female Caregivers Of Community-Dwelling Individuals With Dementia, Laraine Winter, Laura N. Gitlin

Center for Applied Research on Aging and Health Research Papers

Family caregivers, the "second victims" or hidden patients in dementia care, are at risk for social isolation, stress, depression, and mortality. Telephone-based support (telesupport groups) represents a practical, low-burden, low-cost source of emotional support. The present study evaluated the feasibility and effectiveness of professionally led telephone-based support groups for female family caregivers of community-dwelling dementia patients. Recruited through various community sources, 103 female caregivers were randomized to the telesupport group treatment or a control condition. Effects on caregiver burden, depression, and personal gains were evaluated at 6 months, the main end point. Older caregivers (≥65) in telesupport reported lower depression …

Set-Based Cascading Approaches For Magnetic Resonance (Mr) Image Segmentation (Scamis), Jiang Liu, Tze-Yun Leong, Kin Ban Chee, Boon Pin Tan, Borys Shuter, Shih Chang Wang

Research Collection School Of Computing and Information Systems

This paper introduces Set-based Cascading Approach for Medical Image Segmentation (SCAMIS), a new methodology for segmentation of medical imaging by integrating a number of algorithms. Existing approaches typically adopt the pipeline methodology. Although these methods provide promising results, the results generated are still susceptible to over-segmentation and leaking. In our methodology, we describe how set operations can be utilized to better overcome these problems. To evaluate the effectiveness of this approach, Magnetic Resonance Images taken from a teaching hospital research programme have been utilised, to reflect the real world quality needed for testing in patient datasets. A comparison between the …

A Dyadic Examination Of Daily Health Symptoms And Emotional Well-Being In Late-Life Couples, Jeremy B. Yorgason, David Almeida, Shevaun D. Neupert, Avron Spiro Iii, Lesa Hoffman

Department of Psychology: Faculty Publications

This study investigated the link between daily health symptoms and spousal emotional well-being in a sample of 96 older dyads. Higher negative mood and lower positive mood were associated with spousal symptoms in couples wherein husbands or wives reported higher average levels of symptoms. For wives, partner effects were moderated by husbands’ marital satisfaction and illness severity. Specifically, higher husband marital satisfaction and illness severity were associated with higher negative mood and lower positive mood for wives on days where husbands reported higher symptom levels. In their work with later-life families, practitioners and educators should address long-term and daily health-related …

Bovine Immune Response To Shiga-Toxigenic Escherichia Coli O157:H7., Mark A Hoffman, Christian Menge, Thomas A Casey, William Laegreid, Brad T Bosworth, Evelyn A Dean-Nystrom

Manuscripts, Articles, Book Chapters and Other Papers

Although cattle develop humoral immune responses to Shiga-toxigenic (Stx+) Escherichia coli O157:H7, infections often result in long-term shedding of these human pathogenic bacteria. The objective of this study was to compare humoral and cellular immune responses to Stx+ and Stx- E. coli O157:H7. Three groups of calves were inoculated intrarumenally, twice in a 3-week interval, with different strains of E. coli: a Stx2-producing E. coli O157:H7 strain (Stx2+ O157), a Shiga toxin-negative E. coli O157:H7 strain (Stx- O157), or a nonpathogenic E. coli strain (control). Fecal shedding of Stx2+ O157 was significantly higher than that of Stx- O157 or the …

Women’S Health In Developing Countries, Javed Rizvi, Nadeem F. Zuberi

Department of Obstetrics & Gynaecology

Healthcare priorities are different in developing and developed countries. A more effective resource allocation, complemented by efforts to implement only those practices that are effective, should be a priority for improving reproductive health services in developing countries. A large burden of gynaecological disease exists in developing countries and it is difficult to envisage serious reforms and improvements without an increase in public-sector spending. However, communities themselves could assume some responsibility for women's health in ways that prioritize women's own perceptions and primary needs. In this chapter we have compiled existing evidence regarding various gynaecological problems faced by women in developing …

Guidelines And Standards For Performance Of A Pediatric Echocardiogram: A Report From The Task Force Of The Pediatric Council Of The American Society Of Echocardiography., Wyman W. Lai, Tal Geva, Girish S. Shirali, Peter C. Frommelt, Richard A. Humes, Michael M. Brook, Ricardo H. Pignatelli, Jack Rychik, Pediatric Council Of The American Society Of Echocardiography

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

A Multilevel Analysis Of Socioeconomic Status And Prostate Cancer Risk, Maureen Sanderson, Ann L. Coker, Adriana Perez, Xianglin L. Du, Gerson Peltz, Mary K. Fadden

Health & Biomedical Sciences Faculty Publications and Presentations

PURPOSE

We investigated whether prostate cancer was associated with socioeconomic status (SES) at the individual level, area level, or a combination of both levels.

METHODS

This population-based case–control study of prostate cancer in men aged 65 to 79 years was conducted between 2000 and 2002 in South Carolina. Complete interviews were available for 407 incident prostate cancer cases and 393 controls (with respective response rates of 61% and 64%). We used educational level to measure individual-level SES and a composite variable capturing income and education from 2000 Census data to measure area-level SES.

RESULTS

After adjustment for race, age, geographic …

Hormone Effects On Fmri And Cognitive Measures Of Encoding: Importance Of Hormone Preparation, C. E. Gleason, T. W. Schmitz, T. Hess, R. L. Koscik, M. A. Trivedi, M. L. Ries, C. M. Carlsson, M. A. Sager, S. Asthana, S. C. Johnson

Brain and Mind Institute Researchers' Publications

We compared fMRI and cognitive data from nine hormone therapy (HT)-naive women with data from women exposed to either opposed conjugated equine estrogens (CEE) (n = 10) or opposed estradiol (n = 4). Exposure to either form of HT was associated with healthier fMRI response; however, CEE-exposed women exhibited poorer memory performance than either HT-naive or estradiol-exposed subjects. These preliminary findings emphasize the need to characterize differential neural effects of various HTs. ©2006AAN Enterprises, Inc.

Clarification Of Basal Relationships In Rubus (Rosaceae) And The Origin Of Rubus Chamaemorus, Karen Michael

Masters Theses & Specialist Projects

Determination of phylogenetic relationships among ancestral species of Rubus has been elusive. Most Rubus species (including blackberries and raspberries), representing nine of the 12 subgenera, occur in a large, well supported clade named 'A' for reference). The remaining nine species are excluded from this group and represent three subgenera: subg. Anoplobatus (R. bartonianus, R. deliciosus, R. neomexicanus, R. odoratus, R. parviflorus, R. trilobus), subg. Chamaemorus (R. chamaemorus), and subg. Dalibarda (R. lasiococcus, R.pedatus). In addition, Rubus dalibarda L. is often treated in its own monotypic genus as Dalibarda repens L. Phylogenetic analyses of DNA sequence data from chloroplast regions and …

The Power Of Collaboration With Patient Safety Programs: Building Safe Passage For Patients, Nurses, And Clinical Staff, Karlene M. Kerfoot, Kathryn Rapala, Patricia R. Ebright, Suzanne M. Rogers

College of Nursing Faculty Research and Publications

Patient safety is a relatively new field, with many opinions and few effectively proven approaches. One factor is clear: optimal patient safety outcomes cannot be achieved in isolation. Although it is well recognized that multidisciplinary collaboration in the healthcare setting is necessary to effect patient safety, collaboration with resources external to healthcare-academia and industry in particular-will not only aid but also quicken the patient safety efforts. The authors outline a healthcare system's use of all available resources to build a patient safety program.

Combined Effects Of Aldehyde Dehydrogenase Variants And Maternal Mitochondrial Genes On Alcohol Consumption, Yedy Israel, Maria E. Quintanilla, Amalia Sapag, Lutske Tampier

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Two lines of rats bred to differ in their voluntary alcohol consumption — the alcohol-abstaining UChA rats and the alcohol-drinking UChB rats — differ in how effectively toxic acetaldehyde is removed during alcohol metabolism. UChB animals carry efficient variants of the aldehyde dehydrogenase 2 (ALDH2) genes and have active mitochondria, resulting in fast removal of acetaldehyde. UChA animals, in contrast, carry less efficient ALDH2 variants and less active mitochondria, which result in transient elevations of acetaldehyde levels after alcohol ingestion. Cross-breeding studies have demonstrated that the presence of active mitochondria inherited from UChB females can fully abolish the reduction of …

Biomolecular Tuning Of Electronic Transport Properties Of Carbon Nanotubes Via Antibody Functionalization, Kasif Teker, Dr. Eric Wickstrom, Balaji Panchapakesan

Department of Biochemistry and Molecular Biology Faculty Papers

Carbon nanotubes (CNTs) are remarkable solidstate nanomaterials due to their unique electrical and mechanical properties. The electronic properties of nanotubes combined with biological molecules such as proteins could make miniature devices for biological sensing applications. In this paper, the noncovalent interaction of single-wall CNTs with antibodies is presented for its potential applications for detecting overexpressed cell surface receptors in breast cancer cells. The degree of binding of antibodies on CNTs was found to be more than 80% for an extended sampling area by confocal microscopy. The key to achieve such high degree of functionalization is due to the separation of …

Cognitive Impairment And Substance Abuse: Implications For Treatment Planning, Hunter Downing Alessi, Mary Ballard, Alan Kirk, Nicholas Montalbano

Faculty Articles

The cognitive abilities of 24 males at an in-patient substance abuse facility were assessed using the Neurobehavioral Cognitive Status Examination (Cognistat). Findings suggested that there were significant changes in cognitive functioning during the 21-day in-patient treatment as measured by the Cognistat. Implications for mental health professionals working with this population are discussed.

Arkansas Animal Science Department Report 2006, Zelpha B. Johnson, D. Wayne Kellogg

Arkansas Agricultural Experiment Station Research Series

No abstract provided.

Chemoprevention Of Breast Cancer For Women At Hgh Risk, Kathryn Chan, Gloria J. Morris

Department of Medicine Faculty Papers

Breast cancer remains the second most common cause of cancer death in the United States. Several studies have identified cohorts of women at higher than average risk to develop this disease. These are women who are exposed to high levels of endogenous or exogenous estrogens, those with a family history of breast cancer, and those who harbor benign breast disease or genetic mutations that predispose to breast cancer. In this population group, adapting a chemoprevention strategy to decrease the risk of developing overt disease is a strong consideration. To this end, tamoxifen is the most accepted agent to date. This …

Psychometric Properties Of The Readiness For Hospital Discharge Scale, Marianne Weiss, Linda Piacentine

College of Nursing Faculty Research and Publications

The purpose of the study was to assess the psychometrics properties of the Readiness for Hospital Discharge Scale (RHDS), a 23-item instrument that measures patients' perception of readiness for discharge. Data were obtained from 356 respondents from two urban tertiary medical centers (adult and children's) in the midwestern United States who were participants in a larger study of predictors and outcomes of readiness for hospital discharge. Confirmatory factor analysis, contrasted group comparisons, and predictive validity testing supported the 4-factor structure and construct validity of the instrument. Following deletion of two poorly performing items, Cronbach's alpha for the revised 21item scale …