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Selected Works

1997

Articles 1 - 9 of 9

Full-Text Articles in Medicine and Health Sciences

Sequential Expression Of Egr-1 And Egr-3 In Hippocampal Granule Cells Following Electroconvulsive Stimulation, Kevin O'Donovan Oct 1997

Sequential Expression Of Egr-1 And Egr-3 In Hippocampal Granule Cells Following Electroconvulsive Stimulation, Kevin O'Donovan

Kevin O'Donovan

No abstract provided.

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Spiroplasma Lineolae Sp. Nov., From The Horsefly Tabanus Lineola (Diptera : Tabanidae), Frank E. French, Robert F. Whitcomb, Joseph G. Tully, Patricia Carle, Joseph M. Bové, Roberta B. Henegar, Jean R. Adams, Gail E. Gasparich, David L. Williamson Sep 1997

Spiroplasma Lineolae Sp. Nov., From The Horsefly Tabanus Lineola (Diptera : Tabanidae), Frank E. French, Robert F. Whitcomb, Joseph G. Tully, Patricia Carle, Joseph M. Bové, Roberta B. Henegar, Jean R. Adams, Gail E. Gasparich, David L. Williamson

Gail Gasparich

Spiroplasma strain TALS-2T from the viscera of the striped horsefly, Tabanus lineola, collected in Georgia was serologically distinct from other Spiroplasma species, groups, putative groups, and subgroups. Light and electron microscopy of cells of strain TALS-2T revealed helical motile cells surrounded only by a single cytoplasmic membrane. The organism grew in M1D and SP-4 liquid media. Growth also occurred in 1% serum fraction medium and in conventional horse serum medium. Growth in liquid media was serum dependent. The strain passed through 220-nm filter pores, but was retained in filters with 100-nm pores. The optimum temperature for growth was 30°C. Multiplication …

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Collaborative Roles For C-Jun N-Terminal Kinase, C-Jun, Serum Response Factor, And Sp1 In Calcium-Regulated Myocardial Gene Expression, Patrick M. Mcdonough, Deanna S. Hanford, Amy B. Sprenkle, Noel R. Mellon, Christopher C. Glembotski Sep 1997

Collaborative Roles For C-Jun N-Terminal Kinase, C-Jun, Serum Response Factor, And Sp1 In Calcium-Regulated Myocardial Gene Expression, Patrick M. Mcdonough, Deanna S. Hanford, Amy B. Sprenkle, Noel R. Mellon, Christopher C. Glembotski

Amy Sprenkle

Electrical stimulation of contractions (pacing) of primary neonatal rat ventricular myocytes increases intracellular calcium and activates a hypertrophic growth program that includes expression of the cardiac-specific gene, atrial natriuretic factor (ANF). To investigate the mechanism whereby pacing increases ANF, pacing was tested for its ability to regulate mitogen-activated protein kinase family members, ANF promoter activity, and the trans-activation domain of the transcription factor, Sp1. Pacing and the calcium channel agonist BAYK 8644 activated c-Jun N-terminal kinase (JNK) but not extracellular signal-regulated kinase. Pacing stimulated ANF-promoter activity approximately 10-fold. Furthermore, transfection with an expression vector for c-Jun, a substrate for JNK, …

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Attitudes And Perceptions Of Nurses Regarding Early Communication Intervention, Brenda Louw, Ingrid Weber Feb 1997

Attitudes And Perceptions Of Nurses Regarding Early Communication Intervention, Brenda Louw, Ingrid Weber

Brenda Louw

Although nurses play a vital role during Early Communication Intervention with infants and toddlers 0-2 years, limited research has been conducted regarding this role.

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A National Epidemiological Survey Of Oral Mucosal Lesions In Malaysia, Rosnah Binti Zain, Ikeda N., Razak I. A., Axéll T., Majid Z. A., Gupta P. C., Yaacob M. Dec 1996

A National Epidemiological Survey Of Oral Mucosal Lesions In Malaysia, Rosnah Binti Zain, Ikeda N., Razak I. A., Axéll T., Majid Z. A., Gupta P. C., Yaacob M.

Prof. Dr. Rosnah Binti Zain

The prevalence of oral mucosal lesions in Malaysia was determined by examining a representative sample of 11707 subjects aged 25 years and above throughout the 14 states over a period of 5 months during 1993/1994. A two-stage stratified random sampling was undertaken. A predetermined number of enumeration blocks, the smallest population unit in the census publication, was selected from each state. With the selected enumeration block, a systematic sample of living quarters was chosen with a random start. The survey instrument included a questionnaire on sociodemographic characteristics and a clinical examination. The clinical examination was carried out by 16 specially …

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The Effect Of Silica Inhibition Of Macrophage On Renal Allograft Rejection, Carman A. Giacomantonio Dec 1996

The Effect Of Silica Inhibition Of Macrophage On Renal Allograft Rejection, Carman A. Giacomantonio

Vivian C. McAlister

Kidney failure, one of the most serious complications of diabetes is routinely managed by kidney allograft transplantation. Research into the etiology of diabetes has revealed that macrophages are primarily responsible for the β-islet cell destruction in diabetes and that depletion of macrophages using intraperitoneal (i.p.) silica, which is selectively toxic to macrophages, prevents this. Macrophages accounts for approximately 50% of the graft infiltrating cells (GIC) observed in an acutely rejecting kidney, a process phenotypically very similar to a delayed type hypersensitivity (DTH) reaction. Macrophages are known to be essential for DTH reactions. Their exact role has never been elucidated in …

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Spinal Cord Injury - Special Interest Group Combined Sections Meeting: Thursday, Feb. 13, 1997 Business Meeting Minutes, Sarah A. Morrison Dec 1996

Spinal Cord Injury - Special Interest Group Combined Sections Meeting: Thursday, Feb. 13, 1997 Business Meeting Minutes, Sarah A. Morrison

Sarah Morrison, PT, MBA, MHA

No abstract provided.

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The Role Of Rejection In Aortic Valve Allograft Failure, Ahmad Moustapha Dec 1996

The Role Of Rejection In Aortic Valve Allograft Failure, Ahmad Moustapha

Vivian C. McAlister

At present the main question is whether homograft failure is due to rejection or mechanical degeneration. The use of cardiac valve transplants between syngeneic and allogeneic strains of rats permits investigations into the role of immune mediated rejection of these grafts. We expanded an already developed microsurgical rat model for aortic interposition allografts to include the aortic valve. Aortic valves were harvested from donor rats and then heterotopically transplanted into the abdominal aorta of a recipient rat using inbred strains. All recipient rats were Lewis and donor rats were either Lewis (syngeneic) or Brown Norway (allogeneic). Grafts were transplanted either …

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Aortic Valve Grafts In The Rat: Evidence For Rejection., Ahmad Moustapha, David Ross, B Bittira, D Vanvelzen, C L. Lannon, Vivian C. Mcalister, Tim D. Lee Dec 1996

Aortic Valve Grafts In The Rat: Evidence For Rejection., Ahmad Moustapha, David Ross, B Bittira, D Vanvelzen, C L. Lannon, Vivian C. Mcalister, Tim D. Lee

Vivian C. McAlister

OBJECTIVE:
The histopathologic changes of fresh rat aortic valve allografts over time and the effect of cryopreservation were examined.
METHODS:
Fifty-six syngeneic and allogeneic rat aortic valves were transplanted, either fresh or after cryopreservation, and then at different time points they were explanted and histologically examined in a blinded fashion.
RESULTS:
Histopathologic changes in the first week are similar in syngeneic and allogeneic grafts. Fresh syngeneic grafts and leaflets retained normal structure up to 56 days. Allogeneic grafts showed retrovalvular thrombus formation with leaflet ghosts and neointimal proliferation. Cryopreservation did not alter this process.
CONCLUSIONS:
Cardiac allograft valves in the …

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